Sign in to edit your profile (add interests, mentoring, photo, etc.)
    Keywords
    Last Name
    Institution

    Lisa A Lewis PhD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentMedicine
    AddressUniversity of Massachusetts Medical School
    364 Plantation Street, LRB
    Worcester MA 01605
    Phone508-856-8587
        Bibliographic 
        selected publications
        List All   |   Timeline
        1. Gulati S, Zheng B, Reed GW, Su X, Cox AD, St Michael F, Stupak J, Lewis LA, Ram S, Rice PA. Immunization against a Saccharide Epitope Accelerates Clearance of Experimental Gonococcal Infection. PLoS Pathog. 2013 Aug; 9(8):e1003559.
          View in: PubMed
        2. Lewis LA, Shafer WM, Dutta Ray T, Ram S, Rice PA. Phosphoethanolamine Residues on the Lipid A Moiety of Neisseria gonorrhoeae Lipooligosaccharide Modulate Binding of Complement Inhibitors and Resistance to Complement-Killing. Infect Immun. 2012 Oct 15.
          View in: PubMed
        3. Toussi DN, Carraway M, Wetzler LM, Lewis LA, Liu X, Massari P. The Amino Acid Sequence of Neisseria lactamica PorB Surface-Exposed Loops Influences Toll-Like Receptor 2-Dependent Cell Activation. Infect Immun. 2012 Oct; 80(10):3417-28.
          View in: PubMed
        4. Lewis LA, Carter M, Ram S. The relative roles of factor h binding protein, neisserial surface protein a, and lipooligosaccharide sialylation in regulation of the alternative pathway of complement on meningococci. J Immunol. 2012 May 15; 188(10):5063-72.
          View in: PubMed
        5. Vu DM, Shaughnessy J, Lewis LA, Ram S, Rice PA, Granoff DM. Enhanced Bacteremia in Human Factor H Transgenic Rats Infected by Neisseria meningitidis. Infect Immun. 2011 Nov 21.
          View in: PubMed
        6. Dutta Ray T, Lewis LA, Gulati S, Rice PA, Ram S. Novel Blocking Human IgG Directed against the Pentapeptide Repeat Motifs of Neisseria meningitidis Lip/H.8 and Laz Lipoproteins. J Immunol. 2011 Apr 15; 186(8):4881-94.
          View in: PubMed
        7. Ram S, Lewis LA, Agarwal S. Meningococcal group w-135 and y capsular polysaccharides paradoxically enhance activation of the alternative pathway of complement. J Biol Chem. 2011 Mar 11; 286(10):8297-307.
          View in: PubMed
        8. Ram S, Lewis LA, Rice PA. Infections of people with complement deficiencies and patients who have undergone splenectomy. Clin Microbiol Rev. 2010 Oct; 23(4):740-80.
          View in: PubMed
        9. Lewis LA, Ngampasutadol J, Wallace R, Reid JE, Vogel U, Ram S. The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement. PLoS Pathog. 2010; 6(7):e1001027.
          View in: PubMed
        10. Serruto D, Spadafina T, Ciucchi L, Lewis LA, Ram S, Tontini M, Santini L, Biolchi A, Seib KL, Giuliani MM, Donnelly JJ, Berti F, Savino S, Scarselli M, Costantino P, Kroll JS, O'Dwyer C, Qiu J, Plaut AG, Moxon R, Rappuoli R, Pizza M, Aricò B. Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3770-5.
          View in: PubMed
        11. Shaughnessy J, Lewis LA, Jarva H, Ram S. Functional comparison of the binding of factor H short consensus repeat 6 (SCR 6) to factor H binding protein from Neisseria meningitidis and the binding of factor H SCR 18 to 20 to Neisseria gonorrhoeae porin. Infect Immun. 2009 May; 77(5):2094-103.
          View in: PubMed
        12. Lewis LA, Choudhury B, Balthazar JT, Martin LE, Ram S, Rice PA, Stephens DS, Carlson R, Shafer WM. Phosphoethanolamine substitution of lipid A and resistance of Neisseria gonorrhoeae to cationic antimicrobial peptides and complement-mediated killing by normal human serum. Infect Immun. 2009 Mar; 77(3):1112-20.
          View in: PubMed
        13. Lewis LA, Ram S, Prasad A, Gulati S, Getzlaff S, Blom AM, Vogel U, Rice PA. Defining targets for complement components C4b and C3b on the pathogenic neisseriae. Infect Immun. 2008 Jan; 76(1):339-50.
          View in: PubMed
        14. Ram S, Ngampasutadol J, Cox AD, Blom AM, Lewis LA, St Michael F, Stupak J, Gulati S, Rice PA. Heptose I glycan substitutions on Neisseria gonorrhoeae lipooligosaccharide influence C4b-binding protein binding and serum resistance. Infect Immun. 2007 Aug; 75(8):4071-81.
          View in: PubMed
        15. Madico G, Welsch JA, Lewis LA, McNaughton A, Perlman DH, Costello CE, Ngampasutadol J, Vogel U, Granoff DM, Ram S. The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance. J Immunol. 2006 Jul 1; 177(1):501-10.
          View in: PubMed
        16. Gulati S, Cox A, Lewis LA, Michael FS, Li J, Boden R, Ram S, Rice PA. Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci. Infect Immun. 2005 Nov; 73(11):7390-7.
          View in: PubMed
        17. Rendl M, Lewis L, Fuchs E. Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol. 2005 Nov; 3(11):e331.
          View in: PubMed
        18. Harrison A, Dyer DW, Gillaspy A, Ray WC, Mungur R, Carson MB, Zhong H, Gipson J, Gipson M, Johnson LS, Lewis L, Bakaletz LO, Munson RS. Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20. J Bacteriol. 2005 Jul; 187(13):4627-36.
          View in: PubMed
        19. Munson RS, Harrison A, Gillaspy A, Ray WC, Carson M, Armbruster D, Gipson J, Gipson M, Johnson L, Lewis L, Dyer DW, Bakaletz LO. Partial analysis of the genomes of two nontypeable Haemophilus influenzae otitis media isolates. Infect Immun. 2004 May; 72(5):3002-10.
          View in: PubMed
        20. Williams WA, Hendrickson A, Gillaspy AF, Dyer DW, Lewis LA. Oligonucleotide analysis by sequential injection before analysis (SIBA) capillary electrophoresis. Anal Biochem. 2003 Feb 1; 313(1):183-5.
          View in: PubMed
        21. Rohde KH, Gillaspy AF, Hatfield MD, Lewis LA, Dyer DW. Interactions of haemoglobin with the Neisseria meningitidis receptor HpuAB: the role of TonB and an intact proton motive force. Mol Microbiol. 2002 Jan; 43(2):335-54.
          View in: PubMed
        22. Lewis LA, Gipson M, Hartman K, Ownbey T, Vaughn J, Dyer DW. Phase variation of HpuAB and HmbR, two distinct haemoglobin receptors of Neisseria meningitidis DNM2. Mol Microbiol. 1999 Jun; 32(5):977-89.
          View in: PubMed
        23. Lewis LA, Sung MH, Gipson M, Hartman K, Dyer DW. Transport of intact porphyrin by HpuAB, the hemoglobin-haptoglobin utilization system of Neisseria meningitidis. J Bacteriol. 1998 Nov; 180(22):6043-7.
          View in: PubMed
        24. Lewis LA, Rohde K, Gipson M, Behrens B, Gray E, Toth SI, Roe BA, Dyer DW. Identification and molecular analysis of lbpBA, which encodes the two-component meningococcal lactoferrin receptor. Infect Immun. 1998 Jun; 66(6):3017-23.
          View in: PubMed
        25. Lewis LA, Gray E, Wang YP, Roe BA, Dyer DW. Molecular characterization of hpuAB, the haemoglobin-haptoglobin-utilization operon of Neisseria meningitidis. Mol Microbiol. 1997 Feb; 23(4):737-49.
          View in: PubMed
        26. Chen CJ, Sparling PF, Lewis LA, Dyer DW, Elkins C. Identification and purification of a hemoglobin-binding outer membrane protein from Neisseria gonorrhoeae. Infect Immun. 1996 Dec; 64(12):5008-14.
          View in: PubMed
        27. Lewis LA, Dyer DW. Identification of an iron-regulated outer membrane protein of Neisseria meningitidis involved in the utilization of hemoglobin complexed to haptoglobin. J Bacteriol. 1995 Mar; 177(5):1299-306.
          View in: PubMed
        28. Quinn ML, Weyer SJ, Lewis LA, Dyer DW, Wagner PM. Insertional inactivation of the gene for the meningococcal lactoferrin binding protein. Microb Pathog. 1994 Oct; 17(4):227-37.
          View in: PubMed
        For assistance with using Profiles, please refer to the online tutorials or contact UMMS Help Desk or call 508-856-8643.
        Lisa's Networks
        Click the "See All" links for more information and interactive visualizations!
        Concepts
        _
        Co-Authors
        _
        Similar People
        _
        Same Department
        Physical Neighbors
        _

        This is an official Page/Publication of the University of Massachusetts Worcester Campus
        Office of the Vice Provost for Research, 55 Lake Ave North, Worcester, Massachusetts 01655
        Questions or Comments? Email: publicaffairs@umassmed.edu Phone: 508-856-1572