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    Last Name

    Ali Akalin MD, PhD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    AddressUniversity of Massachusetts Medical School
    One Innovation Drive, Biotech Three
    Worcester MA 01605

        Board Certification

        - American Board of Pathology

        - Anatomic and Clinical Pathology, 2005

        - Cytopathology, 2007


        1992 M.D.

        Ankara University, School of Medicine, Ankara, Turkey

        2000 Ph.D.

        Virginia Commonwealth University, School of Medicine, Richmond, VA



        Resident in Anatomic and Clinical Pathology, University of Colorado, School of Medicine, Denver, Colorado


        Fellow in Surgical Pathology, University of Colorado, School of Medicine, Denver, Colorado


        Fellow in Cytopathology, University of Massachusetts, School of Medicine, Worcester, MA

        Academic Appointments

        2007 – present

        Assistant Professor, Department of Pathology, University ofMassachusetts, Worcester, MA

        Clinical Appointments

        2007- present

        Staff Pathologist, Department of Pathology, University of Massachusetts, Worcester, MA

        2010- present

        Director of Head & NeckPathology, Department ofPathology, University of Massachusetts, Worcester, MA

        Honors Awards and Grants


        Association of Molecular Pathology Trainee Award, Missouri

        Research Interests :Dr. Akalin's Picture

        Dr. Akalin has broad diagnostic expertise, with interests in head & neck pathology, cytopathology, and pulmonary pathology. He participates in teaching fellows and residents in our department.

        His research interests include:

        - Study of new techniques to improve the diagnostic yield in fine needle aspirations.

        - Specific detection of cervical cancers using cytometry-based molecular diagnostics.

        - Development of radiolabeled biomarkers for the localization of neoplasms.

        - Exploration of new diagnostic and prognostic markers in pulmonary disorders with a focus on lung neoplasms.

        selected publications
        List All   |   Timeline
        1. Mu X, Kon M, Ergin A, Remiszewski S, Akalin A, Thompson CM, Diem M. Statistical analysis of a lung cancer spectral histopathology (SHP) data set. Analyst. 2015 Mar 16; 140(7):2449-64.
          View in: PubMed
        2. Akalin A, Mu X, Kon MA, Ergin A, Remiszewski SH, Thompson CM, Raz DJ, Diem M. Classification of malignant and benign tumors of the lung by infrared spectral histopathology (SHP). Lab Invest. 2015 Apr; 95(4):406-21.
          View in: PubMed
        3. Tsyrkunou AV, Ellison RT, Akalin A, Wiederhold N, Sutton DA, Lindner J, Fan H, Levitz SM, Zivna I. Multifocal Rhizopus microsporus lung infection following brush clearing. Med Mycol Case Rep. 2014 Oct; 6:14-7.
          View in: PubMed
        4. Parnes AN, Akalin A, Quinlan RM, Vijayaraghavan GR. AIRP best cases in radiologic-pathologic correlation: lactating adenoma. Radiographics. 2013 Mar-Apr; 33(2):455-9.
          View in: PubMed
        5. Cornejo KM, Shi M, Akalin A, Uy K, Cagle PT, Fraire AE. Pulmonary papillary adenoma: a case report and review of the literature. J Bronchology Interv Pulmonol. 2013 Jan; 20(1):52-7.
          View in: PubMed
        6. Bird B, Miljkovic MS, Remiszewski S, Akalin A, Kon M, Diem M. Infrared spectral histopathology (SHP): a novel diagnostic tool for the accurate classification of lung cancer. Lab Invest. 2012 Sep; 92(9):1358-73.
          View in: PubMed
        7. Liu X, Cheng D, Gray BD, Wang Y, Akalin A, Rusckowski M, Pak KY, Hnatowich DJ. Radiolabeled Zn-DPA as a potential infection imaging agent. Nucl Med Biol. 2012 Jul; 39(5):709-14.
          View in: PubMed
        8. Liu G, Dou S, Akalin A, Rusckowski M, Streeter PR, Shultz LD, Greiner DL. Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody. Nucl Med Biol. 2012 Jul; 39(5):645-51.
          View in: PubMed
        9. Wang JP, Lee CK, Akalin A, Finberg RW, Levitz SM. Contributions of the MyD88-dependent receptors IL-18R, IL-1R, and TLR9 to host defenses following pulmonary challenge with Cryptococcus neoformans. PLoS One. 2011; 6(10):e26232.
          View in: PubMed
        10. Liu G, Dou S, Baker S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. A preclinical 188Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49. Cancer Biol Ther. 2010 Oct 15; 10(8):767-74.
          View in: PubMed
        11. Liu X, Wang Y, Nakamura K, Kawauchi S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. Auger radiation-induced, antisense-mediated cytotoxicity of tumor cells using a 3-component streptavidin-delivery nanoparticle with 111In. J Nucl Med. 2009 Apr; 50(4):582-90.
          View in: PubMed
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