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    Daniel A Pollen MD

    TitleProfessor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentNeurology
    AddressUniversity of Massachusetts Medical School
    55 Lake Avenue North
    Worcester MA 01655
    Phone508-856-3081
      Other Positions
      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentNeuroscience

        Bibliographic 
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        1. Evans BA, Evans JE, Baker SP, Kane K, Swearer J, Hinerfeld D, Caselli R, Rogaeva E, St George-Hyslop P, Moonis M, Pollen DA. Long-term statin therapy and CSF cholesterol levels: implications for Alzheimer's disease. Dement Geriatr Cogn Disord. 2009; 27(6):519-24.
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        2. Hinerfeld DA, Moonis M, Swearer JM, Baker SP, Caselli RJ, Rogaeva E, St George-Hyslop P, Pollen DA. Statins differentially affect amyloid precursor protein metabolism in presymptomatic PS1 and non-PS1 subjects. Arch Neurol. 2007 Nov; 64(11):1672-3.
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        3. Klunk WE, Price JC, Mathis CA, Tsopelas ND, Lopresti BJ, Ziolko SK, Bi W, Hoge JA, Cohen AD, Ikonomovic MD, Saxton JA, Snitz BE, Pollen DA, Moonis M, Lippa CF, Swearer JM, Johnson KA, Rentz DM, Fischman AJ, Aizenstein HJ, DeKosky ST. Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees. J Neurosci. 2007 Jun 6; 27(23):6174-84.
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        4. Moonis M, Swearer JM, Dayaw MP, St George-Hyslop P, Rogaeva E, Kawarai T, Pollen DA. Familial Alzheimer disease: decreases in CSF Abeta42 levels precede cognitive decline. Neurology. 2005 Jul 26; 65(2):323-5.
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        5. Pollen DA. Brain stimulation and conscious experience: electrical stimulation of the cortical surface at a threshold current evokes sustained neuronal activity only after a prolonged latency. Conscious Cogn. 2006 Sep; 15(3):560-5.
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        6. Pollen DA. Brain stimulation and conscious experience. Conscious Cogn. 2004 Sep; 13(3):626-45.
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        7. Pollen DA. Explicit neural representations, recursive neural networks and conscious visual perception. Cereb Cortex. 2003 Aug; 13(8):807-14.
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        8. Pollen DA, Przybyszewski AW, Rubin MA, Foote W. Spatial receptive field organization of macaque V4 neurons. Cereb Cortex. 2002 Jun; 12(6):601-16.
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        9. Ishii K, Lippa C, Tomiyama T, Miyatake F, Ozawa K, Tamaoka A, Hasegawa T, Fraser PE, Shoji S, Nee LE, Pollen DA, St George-Hyslop PH, Ii K, Ohtake T, Kalaria RN, Rossor MN, Lantos PL, Cairns NJ, Farrer LA, Mori H. Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition. Neurobiol Aging. 2001 May-Jun; 22(3):367-76.
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        10. Lippa CF, Swearer JM, Kane KJ, Nochlin D, Bird TD, Ghetti B, Nee LE, St George-Hyslop P, Pollen DA, Drachman DA. Familial Alzheimer's disease: site of mutation influences clinical phenotype. Ann Neurol. 2000 Sep; 48(3):376-9.
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        11. Przybyszewski AW, Gaska JP, Foote W, Pollen DA. Striate cortex increases contrast gain of macaque LGN neurons. Vis Neurosci. 2000 Jul-Aug; 17(4):485-94.
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        12. Grodstein F, Chen J, Pollen DA, Albert MS, Wilson RS, Folstein MF, Evans DA, Stampfer MJ. Postmenopausal hormone therapy and cognitive function in healthy older women. J Am Geriatr Soc. 2000 Jul; 48(7):746-52.
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        13. Pollen DA. On the neural correlates of visual perception. Cereb Cortex. 1999 Jan-Feb; 9(1):4-19.
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        14. Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, Iwatsubo T, Trojanowski JQ. Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol. 1998 Nov; 153(5):1365-70.
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        15. Tamaoka A, Fraser PE, Ishii K, Sahara N, Ozawa K, Ikeda M, Saunders AM, Komatsuzaki Y, Sherrington R, Levesque G, Yu G, Rogaeva E, Shoji S, Nee LE, Pollen DA, Hendriks L, Martin JJ, Van Broeckhoven C, Roses AD, Farrer LA, St George-Hyslop PH, Mori H. Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease. Brain Res Mol Brain Res. 1998 May; 56(1-2):178-85.
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        16. Lippa CF, Saunders AM, Smith TW, Swearer JM, Drachman DA, Ghetti B, Nee L, Pulaski-Salo D, Dickson D, Robitaille Y, Bergeron C, Crain B, Benson MD, Farlow M, Hyman BT, George-Hyslop SP, Roses AD, Pollen DA. Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. Neurology. 1996 Feb; 46(2):406-12.
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        17. Pollen DA. Cortical areas in visual awareness. Nature. 1995 Sep 28; 377(6547):293-5.
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        18. Lippa CF, Smith TW, Nee L, Robitaille Y, Crain B, Dickson D, Pulaski-Salo D, Pollen DA. Familial Alzheimer's disease and cortical Lewy bodies: is there a genetic susceptibility factor? Dementia. 1995 Jul-Aug; 6(4):191-4.
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        19. Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HA, Haines JL, Perkicak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St George-Hyslop PH. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 1995 Jun 29; 375(6534):754-60.
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        20. Gaska JP, Jacobson LD, Chen HW, Pollen DA. Space-time spectra of complex cell filters in the macaque monkey: a comparison of results obtained with pseudowhite noise and grating stimuli. Vis Neurosci. 1994 Jul-Aug; 11(4):805-21.
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        21. St George-Hyslop P, McLachlan DC, Tsuda T, Rogaev E, Karlinsky H, Lippa CF, Pollen D, Tuda T. Alzheimer's disease and possible gene interaction. Science. 1994 Jan 28; 263(5146):537.
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        22. Chen HW, Jacobson LD, Gaska JP, Pollen DA. Cross-correlation analyses of nonlinear systems with spatiotemporal inputs. IEEE Trans Biomed Eng. 1993 Nov; 40(11):1102-13.
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        23. St George-Hyslop P, Haines J, Rogaev E, Mortilla M, Vaula G, Pericak-Vance M, Foncin JF, Montesi M, Bruni A, Sorbi S, Rainero I, Pinessi L, Pollen D, Polinsky R, Nee L, Kennedy J, Macciardi F, Rogaeva E, Liang Y, Alexandrova N, Lukiw W, Schlumpf K, Tanzi R, Tsuda T, Farrer L, Cantu JM, Duara R, Amaducci L, Bergamini L, Gusella J, Roses A, Crapper McLachlan D, et al. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nat Genet. 1992 Dec; 2(4):330-4.
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        24. Liu Z, Gaska JP, Jacobson LD, Pollen DA. Interneuronal interaction between members of quadrature phase and anti-phase pairs in the cat's visual cortex. Vision Res. 1992 Jul; 32(7):1193-8.
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        25. St George-Hyslop PH, Haines JL, Farrer LA, Polinsky R, Van Broeckhoven C, Goate A, McLachlan DR, Orr H, Bruni AC, Sorbi S, Rainero I, Foncin JF, Pollen D, Cantu JM, Tupler R, Voskresenskaya N, Mayeux R, Growden J, Fried VA, Myers RH, Nee L, Backhovens H, Martin JJ, Rossor M, Owen MJ, Mullan M, Percy ME, Karlinsky H, Rich S, Heston L, Montesi M, Mortilla M, Nacmias N, Gusella JF, Hardy JA, et al. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature. 1990 Sep 13; 347(6289):194-7.
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        26. Gaska JP, Jacobson LD, Pollen DA. Spatial and temporal frequency selectivity of neurons in visual cortical area V3A of the macaque monkey. Vision Res. 1988; 28(11):1179-91.
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        27. Pollen DA, Gaska JP, Jacobson LD. Responses of simple and complex cells to compound sine-wave gratings. Vision Res. 1988; 28(1):25-39.
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        28. St George-Hyslop PH, Tanzi RE, Polinsky RJ, Haines JL, Nee L, Watkins PC, Myers RH, Feldman RG, Pollen D, Drachman D, et al. The genetic defect causing familial Alzheimer's disease maps on chromosome 21. Science. 1987 Feb 20; 235(4791):885-90.
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        29. St George-Hyslop P, Polinsky R, Haines J, Nee L, Tanzi R, Conneally P, Growdon J, Myers R, Pollen D, Drachman D, et al. Search for the familial Alzheimer's disease gene. J Neural Transm Suppl. 1987; 24:13-21.
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        30. Gaska JP, Jacobson LD, Pollen DA. Response suppression by extending sine-wave gratings within the receptive fields of neurons in visual cortical area V3A of the macaque monkey. Vision Res. 1987; 27(10):1687-92.
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        31. Gaska JP, Pollen DA, Cavanagh P. Diversity of complex cell responses to even- and odd-symmetric luminance profiles in the visual cortex of the cat. Exp Brain Res. 1987; 68(2):249-59.
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        32. Foster KH, Gaska JP, Nagler M, Pollen DA. Spatial and temporal frequency selectivity of neurones in visual cortical areas V1 and V2 of the macaque monkey. J Physiol. 1985 Aug; 365:331-63.
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        33. Pollen DA, Nagler M, Daugman J, Kronauer R, Cavanagh P. Use of Gabor elementary functions to probe receptive field substructure of posterior inferotemporal neurons in the owl monkey. Vision Res. 1984; 24(3):233-41.
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        34. Ronner SF, Foote WE, Pollen DA. Intracortical microstimulation of neurons in the visual cortex of the cat. Electroencephalogr Clin Neurophysiol. 1981 Oct; 52(4):375-7.
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        35. Pollen DA, Ronner SF. Phase relationships between adjacent simple cells in the visual cortex. Science. 1981 Jun 19; 212(4501):1409-11.
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        36. Pollen DA, Feldon SE. Spatial periodicities of periodic complex cells in the visual cortex cluster at one-half octave intervals. Invest Ophthalmol Vis Sci. 1979 Apr; 18(4):429-34.
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        37. Andrews BW, Pollen DA. Relationship between spatial frequency selectivity and receptive field profile of simple cells. J Physiol. 1979 Feb; 287:163-76.
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        38. Pollen DA, Andrews BW, Feldon SE. Spatial frequency selectivity of periodic complex cells in the visual cortex of the cat. Vision Res. 1978; 18(6):665-82.
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        39. Feldon SE, Andrews BW, Pollen DA. Periodic complex cells in cortical area 19 of the cat. Vision Res. 1978; 18(3):347-50.
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        40. Pollen DA. Responses of single neurons to electrical stimulation of the surface of the visual cortex. Brain Behav Evol. 1977 Feb; 14(1-2):67-86.
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        41. Bodis-Wollner IG, Pollen DA, Ronner SF. Responses of complex cells in the visual cortex of the cat as a function of the length of moving slits. Brain Res. 1976 Nov 5; 116(2):205-16.
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        42. Pollen DA, Ronner SF. Periodic excitability changes across the receptive fields of complex cells in the striate and parastriate cortex of the cat. J Physiol. 1975 Mar; 245(3):667-97.
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        43. Rybicki GB, Tracy DM, Pollen DA. Complex cell response depends on interslit spacing. Nat New Biol. 1972 Nov 15; 240(98):77-8.
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        44. Pollen DA, Trachtenberg MC. Some problems of occipital alpha block in man. Brain Res. 1972 Jun 22; 41(2):303-14.
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        45. Pollen DA, Trachtenberg MC. Alpha rhythm and eye movements in eidetic imagery. Nature. 1972 May 12; 237(5350):109-12.
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        46. Mittenthal JE, Kristan WB, Tatton WG, Kripke B, Pollen DA, Taylor JH, Lee JR. Does the striate cortex begin reconstruction of the visual world? Science. 1972 Apr 21; 176(4032):316-9.
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        47. Pollen DA, Lee JR, Taylor JH. How does the striate cortex begin the reconstruction of the visual world? Science. 1971 Jul 2; 173(3991):74-7.
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        48. Trachtenberg MC, Pollen DA. Neuroglia: biophysical properties and physiologic function. Science. 1970 Feb 27; 167(3922):1248-52.
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        49. Pollen DA, Trachtenberg MC. Neuroglia: gliosis and focal epilepsy. Science. 1970 Feb 27; 167(3922):1252-3.
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        50. Jacobson S, Pollen DA. Electrotonic spread of dendritic potentials in feline pyramidal cells. Science. 1968 Sep 27; 161(3848):1351-3.
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        51. Pollen DA. Experimental spike and wave responses and petit mal epilepsy. Epilepsia. 1968 Sep; 9(3):221-32.
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        52. Pollen DA, Lux HD. Conductance changes during inhibitory postsynaptic potentials in normal and strychninized cortical neurons. J Neurophysiol. 1966 May; 29(3):369-81.
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        53. Pollen DA, Lux HD. Intrinsic triggering mechanisms in focal paroxysmal discharges. Epilepsia. 1966 Mar; 7(1):16-22.
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        54. Lux HD, Pollen DA. Electrical constants of neurons in the motor cortex of the cat. J Neurophysiol. 1966 Mar; 29(2):207-20.
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        55. POLLEN DA. INTRACELLULAR STUDIES OF CORTICAL NEURONS DURING THALAMIC INDUCED WAVE AND SPIKE. Electroencephalogr Clin Neurophysiol. 1964 Oct; 17:398-404.
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        56. POLLEN DA, REID KH, PEROT P. MICRO-ELECTRODE STUDIES OF EXPERIMENTAL 3/SEC WAVE AND SPIKE IN THE CAT. Electroencephalogr Clin Neurophysiol. 1964 Jul; 17:57-67.
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        57. SOLOMON AK, LOUCKS J, POLLEN DA, GILL TJ, WOLF E. Search for a potassium compartment in the human red cell membrane. Nature. 1957 Nov 9; 180(4593):993-4.
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