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    Last Name

    Susanne Muehlschlegel MD, MPH

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    AddressUniversity of Massachusetts Medical School
    55 Lake Avenue North
    Worcester MA 01655
      Other Positions
      InstitutionUMMS - School of Medicine

      InstitutionUMMS - School of Medicine

        awards and honors
        Germany1995German Chemical Industry Award (Outstanding Achievement, Chemistry Major), German Chemical Industry
        Studienstiftung des Deutschen Volkes1995 - 2002Studienstiftung des Deutschen Volkes (German National Merit) Scholarship
        University of Florida2004Neuroscience Resident Teacher of the Year
        University of Florida2005Neurology Resident Teacher of the Year
        University of Florida2006Neurology Resident Teacher of the Year
        University of Florida College of Medicine2006Alpha Omega Alpha (Staff Member)
        American Academy of Neurology2006American Academy of Neurology Neurobowl® Resident team player
        University of Massachusetts2009Clinical Excellence Award “Organ Donation”
        University of Massachusetts 2010Clinical Excellence Award “Acute Stroke Team Member”
        UMASS Medical School2010WFBR Grant,
        University of Massachusetts 2011Clinical Excellence Award “Organ Donation”
        University of Massachusetts Medical School2011 - 2012Faculty Scholar Award (awarded to women faculty at UMASS Medical School for outstanding research)
        American Academy of Neurology2012 - 2014Councilor, Executive Committee of the Critical Care and Emergency Neurology Section
        Neurocritical Care Society2013Presidential Citation for Outstanding Contributions to Neurocritical Care
        Neurocritical Care Society2013 - 2017Board of Directors

        Dr. Muehlschlegel completed clinical training in neurology, vascular neurology and neurocritical care, and is triple board certified in these subspecialties. She has obtained additional research training through the completion of the Harvard School of Public Health Summer Program for Clinical Effectiveness and Masters of Public Health Program, with a focus in Clinical Effectiveness. During fellowship, under the mentorship of neurointensivist, translational scientist and director of neurocritical care at Massachusetts General Hospital (MGH), John R. Sims, MD, she became initially engaged in cerebral vasoconstriction syndromes and studying dantrolene as a novel means for prevention and treatment of cerebral vasospasm after subarachnoid hemorrhage, as well as in the reversible vasoconstriction syndrome “Call-Fleming-Syndrome”. Her work was funded by the American Heart Association Scientist Development Grant, and the 2010 Worcester Research Foundation, and results of her investigator initiated feasibility trial of Dantrolene after subarachnoid hemorrhage is in prepartion for publication. Supported by the University of Massachussetts Medical School (UMASS) Faculty Scholar award (to support women in research during times of increased family responsibilities), she turned to her passion: improving the outcome prognostication of moderate-severe traumatic brain injury admitted to the neurointensive care unit. Mentored by senior epidemiologist Robert Goldberg, PhD, she is studying the longitudinal course of critically ill TBI patients, creating new prediction tools, and demonstrating the variability of outcome prognostication by clinicians. She is currently interested in developing shared decision making tools, which may ultimately limit uninformed withdrawal of care or futile prolongation of life decisions by families and physician biases ( This work is in line with the Patient Protection and Affordable Care Act of 2010 which supports a national shared decision making program

        Dr. Muehlschlegel and her colleague Dr. Carandang are the co-founders of the New England Neurocritical Care Research Consortium (NENCC), a regional consortium consisting of MGH, UMASS, BWH, Boston Medical Center, Yale, Baystate Medical Center and Rhode Island Hospital, with the goal of facilitating collaborative multi-center research in neurocritical care.

        Dr. Muehlschlegel is the co-chair of the Neurocritical Care Society Website Committee (, and member of the newsletter editorial board. Since 2013, she has been an elected member of the Board of Directors of the Neurocritical Care Society, and is currently serving a 4-year term. The Neurocritical Care Society is the largest international multidisciplinary neurocritical care professional society dedicated to improve the health care and outcomes of patients with life-threatening neurological illnesses by promoting quality patient care, professional collaboration, research, training and advocacy.

        Dr. Muehlschlegel is a well-recognized teacher. She has been was actively involved in daily teaching of medical students and residents in neurology and other disciplines since residency. As a chief resident she organized bi-weekly neurology board review sessions, as well as other regular teaching conferences and journal clubs. As a fellow, her teaching efforts continued, and involved daily resident education sessions during or after rounds on acute stroke and neurointensive care issues. She initiated a combined lecture series of surgical ICU and neuro-ICU fellows. She was actively involved as a lecturer at the ACLS course for health care providers at MGH. As a UMASS faculty member, Dr. Muehlschlegel is currently responsible for the supervision of surgical critical care fellows, residents, medical students and mid-level providers (PA/ARNP) in the trauma and neuro-ICU. She established a regular bi-weekly teaching lecture series for the mid-level providers specialized in neuro-ICU. She gives lectures regularly to neurology, emergency medicine, anesthesia and surgery residents. When on service in the ICU, she provides teaching to the ICU team with all its members during the daily SICU morning lectures. She teaches all ICU procedures as well as all clinical aspects of neurocritical care. She has been co-director of the UMASS Department of Neurology/Neuroscience Journal Club since 2008.

        As a neurointensivist, Dr. Muehlschlegel is one of only approximately 500 U.S. board certified subspecialists in this field. She is involved in the direct care of critically ill neurology, neurosurgery and trauma patients. She managed all neuroICU and general surgical ICU problems, including but not limited to ventilators, hemodynamics, sepsis, nutrition, electrolyte imbalances, acid-base disorders, infections, and ventriculostomies. She is known to communicate very effectively and empathetically with family members and establishes great rapport with patients and affected families.


        Post-Graduate Medical and Research Training:

        2002-2006 -- Neurology Residency, University of Florida

        2005-2006 -- Chief Resident (Neurology), University of Florida

        2006-2008 -- Neurocritical Care and Vascular Neurology Fellowship, Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School

        2007-2010 -- Masters of Public Health (Clinical Effectiveness), Harvard School of Public Health


        Rotation Projects
        Lab rotations are available for undergraduate and medical students, residents and fellows. Visiting students from abroad should inquire about visa requirements first before applying.

        selected publications
        List All   |   Timeline
        1. Henninger N, Izzy S, Carandang R, Hall W, Muehlschlegel S. Severe Leukoaraiosis Portends a Poor Outcome After Traumatic Brain Injury. Neurocrit Care. 2014 Apr 22.
          View in: PubMed
        2. Muehlschlegel, S; Carandang, R; Hall, W; Kini, N; Izzy, S; Garland, B; Ouillette, C; VanDerBom, IM; Flood, TF; Gounis, MJ; Weaver, JP; Barton, B; Wakhloo, AK. Dantrolene for Cerebral Vasospasm after Subarachnoid Hemorrhage: Randomized, double blind, placebo-controlled safety trial (Under Review). 2014.
        3. Osgood, M.; Carandang, C; Compton, R; Hall, W; Kershaw, G; Muehlschlegel, S. Rapid Unexpected Brain Herniation in Association with Modern Renal Replacement Therapy in Acute Brain Injury (Under Review). 2014.
        4. Izzy S, Muehlschlegel S. Cerebral vasospasm after aneurysmal subarachnoid hemorrhage and traumatic brain injury. Curr Treat Options Neurol. 2014 Jan; 16(1):278.
          View in: PubMed
        5. Izzy S, Compton R, Carandang R, Hall W, Muehlschlegel S. Self-fulfilling prophecies through withdrawal of care: do they exist in traumatic brain injury, too? Neurocrit Care. 2013 Dec; 19(3):347-63.
          View in: PubMed
        6. Muehlschlegel S, Kursun O, Topcuoglu MA, Fok J, Singhal AB. Differentiating reversible cerebral vasoconstriction syndrome with subarachnoid hemorrhage from other causes of subarachnoid hemorrhage. JAMA Neurol. 2013 Oct; 70(10):1254-60.
          View in: PubMed
        7. Muehlschlegel S, Carandang R, Ouillette C, Hall W, Anderson F, Goldberg R. Frequency and impact of intensive care unit complications on moderate-severe traumatic brain injury: early results of the Outcome Prognostication in Traumatic Brain Injury (OPTIMISM) Study. Neurocrit Care. 2013 Jun; 18(3):318-31.
          View in: PubMed
        8. Tisdell J, Smith TW, Muehlschlegel S. Multiple septic brain emboli in infectious endocarditis. Arch Neurol. 2012 Sep; 69(9):1206-7.
          View in: PubMed
        9. Rivera-Lara L, Zhang J, Muehlschlegel S. Therapeutic hypothermia for acute neurological injuries. Neurotherapeutics. 2012 Jan; 9(1):73-86.
          View in: PubMed
        10. Muehlschlegel S, Rordorf G, Sims J. Effects of a single dose of dantrolene in patients with cerebral vasospasm after subarachnoid hemorrhage: a prospective pilot study. Stroke. 2011 May; 42(5):1301-6.
          View in: PubMed
        11. Muehlschlegel S, Selb J, Patel M, Diamond SG, Franceschini MA, Sorensen AG, Boas DA, Schwamm LH. Feasibility of NIRS in the neurointensive care unit: a pilot study in stroke using physiological oscillations. Neurocrit Care. 2009; 11(2):288-95.
          View in: PubMed
        12. Muehlschlegel S, Voetsch B, Sorond FA. Emergent epidural blood patch: lifesaving treatment of paradoxical herniation. Arch Neurol. 2009 May; 66(5):670-1.
          View in: PubMed
        13. Muehlschlegel S, Sims JR. Dantrolene: mechanisms of neuroprotection and possible clinical applications in the neurointensive care unit. Neurocrit Care. 2009; 10(1):103-15.
          View in: PubMed
        14. Muehlschlegel S, Rordorf G, Bodock M, Sims JR. Dantrolene mediates vasorelaxation in cerebral vasoconstriction: a case series. Neurocrit Care. 2009; 10(1):116-21.
          View in: PubMed
        15. Muehlschlegel S, Goddeau RP, Sims JR. Teaching NeuroImage: Cerebral T-waves from an aneurysmal cardunculus compression. Neurology. 2008 Feb 12; 70(7):e28-9.
          View in: PubMed
        16. Muehlschlegel S, Voetsch B, Singhal AB. CT angiography and CT perfusion in post-CEA hyperperfusion syndrome. Neurology. 2007 Apr 24; 68(17):1437.
          View in: PubMed
        17. Muehlschlegel S, Dunser MW, Gabrielli A, Wenzel V, Layon AJ. Arginine vasopressin as a supplementary vasopressor in refractory hypertensive, hypervolemic, hemodilutional therapy in subarachnoid hemorrhage. Neurocrit Care. 2007; 6(1):3-10.
          View in: PubMed
        18. Muehlschlegel S, Lobato EB. Con: all cardiac surgical patients should not have intraoperative cerebral oxygenation monitoring. J Cardiothorac Vasc Anesth. 2006 Aug; 20(4):613-5.
          View in: PubMed
        19. Muehlschlegel S, Okun MS, Foote KD, Coco D, Yachnis AT, Fernandez HH. Paraneoplastic chorea with leukoencephalopathy presenting with obsessive-compulsive and behavioral disorder. Mov Disord. 2005 Nov; 20(11):1523-7.
          View in: PubMed
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