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    Alexander Sloutsky PhD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentMedicine
    Address305 South Street
    Jamaica Plain MA 02130
    Phone617-983-6370
        Bibliographic 
        selected publications
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        1. Mitnick CD, Franke MF, Rich ML, Alcantara Viru FA, Appleton SC, Atwood SS, Bayona JN, Bonilla CA, Chalco K, Fraser HS, Furin JJ, Guerra D, Hurtado RM, Joseph K, Llaro K, Mestanza L, Mukherjee JS, Muñoz M, Palacios E, Sanchez E, Seung KJ, Shin SS, Sloutsky A, Tolman AW, Becerra MC. Aggressive regimens for multidrug-resistant tuberculosis decrease all-cause mortality. PLoS One. 2013; 8(3):e58664.
          View in: PubMed
        2. Barczak AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L, Borowsky ML, Onderdonk AB, Stanley SA, Kaur D, Bryant KF, Knipe DM, Sloutsky A, Hung DT. RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities. Proc Natl Acad Sci U S A. 2012 Apr 17; 109(16):6217-22.
          View in: PubMed
        3. Weiner B, Gomez J, Victor TC, Warren RM, Sloutsky A, Plikaytis BB, Posey JE, van Helden PD, Gey van Pittius NC, Koehrsen M, Sisk P, Stolte C, White J, Gagneux S, Birren B, Hung D, Murray M, Galagan J. Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region. PLoS One. 2012; 7(2):e26038.
          View in: PubMed
        4. Shiryaev SA, Cieplak P, Aleshin AE, Sun Q, Zhu W, Motamedchaboki K, Sloutsky A, Strongin AY. Matrix metalloproteinase proteolysis of the mycobacterial HSP65 protein as a potential source of immunogenic peptides in human tuberculosis. FEBS J. 2011 Sep; 278(18):3277-86.
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        5. Cohen T, Murray M, Abubakar I, Zhang Z, Sloutsky A, Arteaga F, Chalco K, Franke MF, Becerra MC. Multiple introductions of multidrug-resistant tuberculosis into households, lima, peru. Emerg Infect Dis. 2011 Jun; 17(6):969-75.
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        6. Kam KM, Sloutsky A, Yip CW, Bulled N, Seung KJ, Zignol M, Espinal M, Kim SJ. Determination of critical concentrations of second-line anti-tuberculosis drugs with clinical and microbiological relevance. Int J Tuberc Lung Dis. 2010 Mar; 14(3):282-8.
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        7. Cho B, Poulsen PR, Sloutsky A, Sawant A, Keall PJ. First demonstration of combined kV/MV image-guided real-time dynamic multileaf-collimator target tracking. Int J Radiat Oncol Biol Phys. 2009 Jul 1; 74(3):859-67.
          View in: PubMed
        8. Pichugin AV, Yan BS, Sloutsky A, Kobzik L, Kramnik I. Dominant role of the sst1 locus in pathogenesis of necrotizing lung granulomas during chronic tuberculosis infection and reactivation in genetically resistant hosts. Am J Pathol. 2009 Jun; 174(6):2190-201.
          View in: PubMed
        9. Pollock NR, Kashino SS, Napolitano DR, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E, Campos-Neto A. Evaluation of the effect of treatment of latent tuberculosis infection on QuantiFERON-TB gold assay results. Infect Control Hosp Epidemiol. 2009 Apr; 30(4):392-5.
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        10. Pollock NR, Campos-Neto A, Kashino S, Napolitano D, Behar SM, Shin D, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E. Discordant QuantiFERON-TB Gold test results among US healthcare workers with increased risk of latent tuberculosis infection: a problem or solution? Infect Control Hosp Epidemiol. 2008 Sep; 29(9):878-86.
          View in: PubMed
        11. Mitnick CD, Shin SS, Seung KJ, Rich ML, Atwood SS, Furin JJ, Fitzmaurice GM, Alcantara Viru FA, Appleton SC, Bayona JN, Bonilla CA, Chalco K, Choi S, Franke MF, Fraser HS, Guerra D, Hurtado RM, Jazayeri D, Joseph K, Llaro K, Mestanza L, Mukherjee JS, Muñoz M, Palacios E, Sanchez E, Sloutsky A, Becerra MC. Comprehensive treatment of extensively drug-resistant tuberculosis. N Engl J Med. 2008 Aug 7; 359(6):563-74.
          View in: PubMed
        12. Pollock N, Westerling J, Sloutsky A. Specimen dilution increases the diagnostic utility of the gen-probe mycobacterium tuberculosis direct test. Am J Clin Pathol. 2006 Jul; 126(1):142-7.
          View in: PubMed
        13. Han LL, Sloutsky A, Canales R, Naroditskaya V, Shin SS, Seung KJ, Timperi R, Becerra MC. Acquisition of drug resistance in multidrug-resistant Mycobacterium tuberculosis during directly observed empiric retreatment with standardized regimens. Int J Tuberc Lung Dis. 2005 Jul; 9(7):818-21.
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        14. Solis LA, Shin SS, Han LL, Llanos F, Stowell M, Sloutsky A. Validation of a rapid method for detection of M. tuberculosis resistance to isoniazid and rifampin in Lima, Peru. Int J Tuberc Lung Dis. 2005 Jul; 9(7):760-4.
          View in: PubMed
        15. Timperi R, Han LL, Sloutsky A, Becerra MC, Nardell EA, Salazar JJ, Smith-Fawzi MC. Drug resistance profiles of Mycobacterium tuberculosis isolates: five years' experience and insight into treatment strategies for MDR-TB in Lima, Peru. Int J Tuberc Lung Dis. 2005 Feb; 9(2):175-80.
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        16. Shin SS, Naroditskaya V, Sloutsky A, Werner B, Timperi R, Bayona J, Farmer PE, Becerra MC. rpoB gene mutations in clinical isolates of multidrug-resistant Mycobacterium tuberculosis in northern Lima, Peru. Microb Drug Resist. 2005; 11(1):26-30.
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        17. Sloutsky A, Han LL, Werner BG. New method for detection of Mycobacterium tuberculosis Direct Test inhibitors in clinical specimens. Diagn Microbiol Infect Dis. 2004 Oct; 50(2):109-11.
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        18. Rengarajan J, Sassetti CM, Naroditskaya V, Sloutsky A, Bloom BR, Rubin EJ. The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria. Mol Microbiol. 2004 Jul; 53(1):275-82.
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        19. Sloutsky A, Han LL, Werner BG. Practical strategies for performance optimization of the enhanced gen-probe amplified mycobacterium tuberculosis direct test. J Clin Microbiol. 2004 Apr; 42(4):1547-51.
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        20. Mukherjee JS, Joseph JK, Rich ML, Shin SS, Furin JJ, Seung KJ, Sloutsky A, Socci AR, Vanderwarker C, Vasquez L, Palacios E, Guerra D, Viru FA, Farmer P, Del Castillo HE. Clinical and programmatic considerations in the treatment of MDR-TB in children: a series of 16 patients from Lima, Peru. Int J Tuberc Lung Dis. 2003 Jul; 7(7):637-44.
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        21. Hazra R, Floyd MM, Sloutsky A, Husson RN. Novel mycobacterium related to Mycobacterium triplex as a cause of cervical lymphadenitis. J Clin Microbiol. 2001 Apr; 39(4):1227-30.
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        22. Becerra MC, Freeman J, Bayona J, Shin SS, Kim JY, Furin JJ, Werner B, Sloutsky A, Timperi R, Wilson ME, Pagano M, Farmer PE. Using treatment failure under effective directly observed short-course chemotherapy programs to identify patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis. 2000 Feb; 4(2):108-14.
          View in: PubMed
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