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    J P Flatt PhD

    TitleProfessor Emeritus
    InstitutionUniversity of Massachusetts Medical School
    DepartmentBiochemistry and Molecular Pharmacology
    AddressUniversity of Massachusetts Medical School
    364 Plantation Street, LRB
    Worcester MA 01605
    Phone508-856-2353
        Bibliographic 
        selected publications
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        1. Flatt JP. Misconceptions in body weight regulation: Implications for the obesity pandemic. Crit Rev Clin Lab Sci. 2012 Jul; 49(4):150-65.
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        2. Flatt JP. Issues and misconceptions about obesity. Obesity (Silver Spring). 2011 Apr; 19(4):676-86.
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        3. Bray GA, Flatt JP, Volaufova J, Delany JP, Champagne CM. Corrective responses in human food intake identified from an analysis of 7-d food-intake records. Am J Clin Nutr. 2008 Dec; 88(6):1504-10.
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        4. Flatt JP. Differences in basal energy expenditure and obesity. Obesity (Silver Spring). 2007 Nov; 15(11):2546-8.
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        5. Flatt JP. Carbohydrate-fat interactions and obesity examined by a two-compartment computer model. Obes Res. 2004 Dec; 12(12):2013-22.
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        6. Brooks GA, Butte NF, Rand WM, Flatt JP, Caballero B. Chronicle of the Institute of Medicine physical activity recommendation: how a physical activity recommendation came to be among dietary recommendations. Am J Clin Nutr. 2004 May; 79(5):921S-930S.
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        7. Flatt JP. Macronutrient composition and food selection. Obes Res. 2001 Nov; 9 Suppl 4:256S-262S.
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        8. Chien D, Dean D, Saha AK, Flatt JP, Ruderman NB. Malonyl-CoA content and fatty acid oxidation in rat muscle and liver in vivo. Am J Physiol Endocrinol Metab. 2000 Aug; 279(2):E259-65.
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        9. Bier DM, Brosnan JT, Flatt JP, Hanson RW, Heird W, Hellerstein MK, Jéquier E, Kalhan S, Koletzko B, Macdonald I, Owen O, Uauy R. Report of the IDECG Working Group on lower and upper limits of carbohydrate and fat intake. International Dietary Energy Consultative Group. Eur J Clin Nutr. 1999 Apr; 53 Suppl 1:S177-8.
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        10. Flatt JP. What do we most need to learn about food intake regulation? Obes Res. 1998 Jul; 6(4):307-10.
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        11. Flatt JP. How NOT to approach the obesity problem. Obes Res. 1997 Nov; 5(6):632-3.
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        12. Tataranni PA, Larson DE, Snitker S, Young JB, Flatt JP, Ravussin E. Effects of glucocorticoids on energy metabolism and food intake in humans. Am J Physiol. 1996 Aug; 271(2 Pt 1):E317-25.
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        13. Flatt JP. Carbohydrate balance and body-weight regulation. Proc Nutr Soc. 1996 Mar; 55(1B):449-65.
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        14. Flatt JP. Glycogen levels and obesity. Int J Obes Relat Metab Disord. 1996 Mar; 20 Suppl 2:S1-11.
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        15. Flatt JP. Body composition, respiratory quotient, and weight maintenance. Am J Clin Nutr. 1995 Nov; 62(5 Suppl):1107S-1117S.
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        16. Flatt JP. Integration of the overall response to exercise. Int J Obes Relat Metab Disord. 1995 Oct; 19 Suppl 4:S31-40.
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        17. Flatt JP. McCollum Award Lecture, 1995: diet, lifestyle, and weight maintenance. Am J Clin Nutr. 1995 Oct; 62(4):820-36.
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        18. Flatt JP. Carbohydrate balance and food intake regulation. Am J Clin Nutr. 1995 Jul; 62(1):155-7.
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        19. Flatt JP. Use and storage of carbohydrate and fat. Am J Clin Nutr. 1995 Apr; 61(4 Suppl):952S-959S.
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        20. Flatt JP. Influence of body composition on food intake. Adv Exp Med Biol. 1994; 352:27-44.
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        21. Flatt JP. Dietary fat, carbohydrate balance, and weight maintenance. Ann N Y Acad Sci. 1993 Jun 14; 683:122-40.
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        22. Flatt JP. Body weight, fat storage, and alcohol metabolism. Nutr Rev. 1992 Sep; 50(9):267-70.
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        23. Schutz Y, Flatt JP, Jéquier E. Failure of dietary fat intake to promote fat oxidation: a factor favoring the development of obesity. Am J Clin Nutr. 1989 Aug; 50(2):307-14.
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        24. Flatt JP. Importance of nutrient balance in body weight regulation. Diabetes Metab Rev. 1988 Sep; 4(6):571-81.
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        25. Acheson KJ, Schutz Y, Bessard T, Anantharaman K, Flatt JP, Jéquier E. Glycogen storage capacity and de novo lipogenesis during massive carbohydrate overfeeding in man. Am J Clin Nutr. 1988 Aug; 48(2):240-7.
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        26. Flatt JP. Dietary fat, carbohydrate balance, and weight maintenance: effects of exercise. Am J Clin Nutr. 1987 Jan; 45(1 Suppl):296-306.
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        27. Acheson KJ, Schutz Y, Bessard T, Flatt JP, Jéquier E. Carbohydrate metabolism and de novo lipogenesis in human obesity. Am J Clin Nutr. 1987 Jan; 45(1):78-85.
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        28. Flatt JP. The difference in the storage capacities for carbohydrate and for fat, and its implications in the regulation of body weight. Ann N Y Acad Sci. 1987; 499:104-23.
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        29. Flatt JP, Ravussin E, Acheson KJ, Jéquier E. Effects of dietary fat on postprandial substrate oxidation and on carbohydrate and fat balances. J Clin Invest. 1985 Sep; 76(3):1019-24.
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        30. Salmon DM, Flatt JP. Effect of dietary fat content on the incidence of obesity among ad libitum fed mice. Int J Obes. 1985; 9(6):443-9.
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        31. Acheson KJ, Schutz Y, Bessard T, Ravussin E, Jéquier E, Flatt JP. Nutritional influences on lipogenesis and thermogenesis after a carbohydrate meal. Am J Physiol. 1984 Jan; 246(1 Pt 1):E62-70.
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        32. Acheson KJ, Flatt JP, Jéquier E. Glycogen synthesis versus lipogenesis after a 500 gram carbohydrate meal in man. Metabolism. 1982 Dec; 31(12):1234-40.
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        33. Moldawer LL, Trerice MS, Flatt JP, Bistrian BR, Blackburn GL. A protein sparing model in the rat during hypocaloric feeding: factors determining preservation of visceral protein function. J Surg Res. 1978 Nov; 25(5):424-32.
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        34. Miller JD, Bistrian BR, Blackburn GL, Flatt JP, Rienhoff H, Trerice M. Failure of postoperative infection to increase nitrogen excretion in patients maintained on peripheral amono acids. Am J Clin Nutr. 1977 Sep; 30(9):1523-7.
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        35. Moldawer LL, Nakano Y, Trerice MS, Etter GP, Bistrian BR, Flatt JP, Blackburn GL. Ability of fat to preserve cell-mediated immunity in rats. Surg Forum. 1977; 28:67-9.
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        36. Bistrian BR, Blackburn GL, Flatt JP, Sizer J, Scrimshaw NS, Sherman M. Nitrogen metabolism and insulin requirements in obese diabetic adults on a protein-sparing modified fast. Diabetes. 1976 Jun; 25(6):494-504.
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        37. Maini B, Blackburn GL, Bistrian BR, Flatt JP, Page JG, Bothe A, Benotti P, Rienhoff HY. Cyclic hyperalimentation: an optimal technique for preservation of visceral protein. J Surg Res. 1976 Jun; 20(6):515-25.
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        38. Blackburn GL, Maini B, Bistrian BR, Flatt JP, Page G, Gibbons G, Sigman D, Cochran D. "Cyclic hyperalimentation" - an optimal technique for preservation of visceral protein mass. Acta Chir Scand Suppl. 1976; 466:50-1.
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        39. Bistrian BR, Blackburn GL, Scrimshaw NS, Flatt JP. Cellular immunity in semistarved states in hospitalized adults. Am J Clin Nutr. 1975 Oct; 28(10):1148-55.
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        40. Rutten P, Blackburn GL, Flatt JP, Hallowell E, Cochran D. Determination of optimal hyperalimentation infusion rate. J Surg Res. 1975 May; 18(5):477-83.
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        41. Flatt JP, Blackburn GL. The matabolic fuel regulatory system: implications for protein-sparing therapies during caloric deprivation and disease. Am J Clin Nutr. 1974 Feb; 27(2):175-87.
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        42. Flatt JP. Role of the increased adipose tissue mass in the apparent insulin insensitivity of obesity. Am J Clin Nutr. 1972 Nov; 25(11):1189-92.
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        43. Flatt JP. Conversion of carbohydrate to fat in adipose tissue: an energy-yielding and, therefore, self-limiting process. J Lipid Res. 1970 Mar; 11(2):131-43.
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        44. FLATT JP, BALL EG. STUDIES ON THE METABOLISM OF ADIPOSE TISSUE. XV. AN EVALUATION OF THE MAJOR PATHWAYS OF GLUCOSE CATABOLISM AS INFLUENCED BY INSULIN AND EPINEPHRINE. J Biol Chem. 1964 Mar; 239:675-85.
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