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    Kristina M Deligiannidis MD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentPsychiatry
    AddressUniversity of Massachusetts Medical School
    328 Shrewsbury Street
    Worcester MA 01604
    Phone508-334-7262
      Other Positions
      InstitutionUMMS - School of Medicine
      DepartmentObstetrics and Gynecology

        Biography 
        awards and honors
        NIH/NICHD1996Summer Intramural Research Training Award;Developmental Endocrinology/Genetics/Neuroendocrinology
        1997Commonwealth Scholar; Univ. of Massachusetts at Amherst
        NIH/NICHD1998 - 2000Predoctoral Intramural Research Training Award;Developmental Endocrinology/Genetics/Neuroendocrine
        NIH/NICHD2003Medical Student Clinical Research Electives Program:Pediatrics & Developmental Neuropsychiatry
        2003 - 2004Charles J. Hoff Scholar; UMass Medical School
        2004T. Byram Karasu Award in Psychotherapy for Medical Students
        2007 - 2008ASCP/NIMH Clinical Trials in Psychopharmacology Award
        2008 - 2009APA/APIRE Junior Investigator Awards
        2009Paul F. Briscoli Award for Resident-Faculty Academic Collaboration; UMass Medical School
        2009Resident Educator Award; UMass Medical School
        NIH/NIMH2009Resident Elective Program in Clinical Research; Experimental Therapeutics/Pathophysiology Branch
        NIH/NIMH2009Resident Elective Program in Clinical Research; Behavioral Endocrinology Branch
        2009ASCP/NCDEU/NIMH New Investigator Award
        2010Worcester Foundation for Biomedical Research Grant
        2011Society for Biological Psychiatry (SOBP) Travel Scholarship Award
        2011Career Development Research Fellowship Award; UMass Medical Dept. Psychiatry
        2011Faculty Scholar Award; UMass Medical School
        NIH/NCATS2011 - 2013NIH/UMass Medical CTSA Pilot Project Program Grant
        2012Faculty Teaching Award for Outstanding Resident Teaching; UMass Medical School Dept. Psychiatry
        NIH/NIMH2012 - 2014Career Development Institute (CDI) for Psychiatry Award (NIMH R25) Univ. Pittsburgh/Stanford Univ.
        NIH/NIMH2013 - 2018NIH/NIMH K23 Career Development Award
        2013Early Career Achievement in Science and Health Award; UMass Medical School
        2013Best Doctors in America
        2013National Network of Depression Centers (NNDC) Annual Scientific Conference Travel Award
        2014ACNP (American College of Neuropsychopharmacology) Travel Award
        NIH/NIMH2014 - 2016NIH/NIMH Clinical Research Loan Repayment Program Award
        NIH/CSR2014NIH Early Career Reviewer, Center for Scientific Review
        Overview 
        Narrative

         

        Dr. Deligiannidis completed her undergraduate degrees and an Honors Scholars Research Program in Neuroscience and Behavior at the University of Massachusetts at Amherst.  As a recipient of NIH pre-doctoral Intramural Research Training Awards, she trained in molecular neuroendocrinology research at the NIH/National Institutes of Child Health and Human Development (NIH/NICHD). 

        Dr. Deligiannidis completed additional research training at the National Institute of Mental Health (NIMH) and NICHD during medical school and residency.  She received her medical degree from the University of Massachusetts Medical School and completed her psychiatry residency and chief residency in psychopharmacology research at UMass Medical School (UMMS)/UMass Memorial Health Care (UMMHC).  Dr. Deligiannidis joined faculty at UMMS in October 2009 as an Assistant Professor of Psychiatry and is Board Certified by the American Board of Psychiatry and Neurology.

        Dr. Deligiannidis is the Director of the Depression Specialty Clinic, a regional referral center at UMMHC that specializes in the evaluation and treatment of adult patients suffering from major depression, psychotic depression, treatment-resistant depression and bipolar depression.

        Dr. Deligiannidis also evaluates and treats women in the Women’s Mental Health Specialty Clinic at UMMHC.  She provides consultation and short-term treatment of women suffering from depression and anxiety during pregnancy or the post-partum period. Her expertise is focused on psychopharmacologic and complementary/alternative treatments for depression/anxiety during the perinatal period.

        Dr. Deligiannidis conducts translational research in the causes of perinatal depression.  She also conducts depression research on novel therapeutics.  Research areas of expertise include:

        • Psychoneuroendocrinology
        • Neuroimaging and neuroendocrine biomarkers of depression in women during perinatal period
        • Gender differences in depression and treatment response
        • Neuroimaging  (MRS, fMRI, fcMRI, DTI)
        • Psychopharmacology clinical trials/novel therapeutics
        • Complementary and alternative/integrative treatments

        Dr. Deligiannidis's research efforts have been nationally recognized.  She is the recipient of: a 2014 ACNP (American College of Neuropsychopharmacology) Travel Award; 2013-2018 NIH K23 Career Development Award, 2014-2016 NIH LRP Award, 2012 Research Career Development Institute (CDI) for Psychiatry Award (University of Pittsburgh/Stanford University), 2011 UMass Medical School Center for Clinical & Translational Science (CTSA) Pilot Grant, a UMMS Faculty Scholar Award, a 2011 Society for Biological Psychiatry Travel Scholarship Award, a 2010 Worcester Foundation for Biomedical Research Grant; a 2009 NIMH/NCDEU New Investigator Award, APA/APIRE Junior Investigator Awards (2008, 2009) and American Society of Clinical Psychopharmacology/NIMH Clinical Trials in Psychopharmacology Awards (2007, 2008).  At UMass, she has received the Early Career Achievement Award in Science and Health (2013) and several teaching awards.

        Dr. Deligiannidis actively participates in national scientific committees and gives scientific presentations locally, regionally and nationally.  She is an appointed Young Investigator Member of the International Society of Psychoneuroendocrinology (ISPNE) and a member of the Society of Biological Psychiatry (SOBP), the Society of Behavioral Neuroendocrinology (SBE), the Organization for Human Brain Mapping (OHBM), and the American Society of Clinical Psychopharmacology (ASCP). 

        She serves on the Board of Directors of ASCP and on the Editorial Board for Acta Psychiatrica Scandinavica, is Co-Chair of the Education Committees for both the ASCP and SOBP and is an Early Career Reviewer at NIH.



        Rotation Projects

        University of Massachusetts Medical School Summer Research Program for Medical Students

        If interested, please contact Dr. Kristina Deligiannidis and read description below.



        University of Massachusetts Medical School Senior Scholars Project

        If interested, please contact Dr. Kristina Deligiannidis to discuss research project ideas.



        University of Massachusetts Medical School Volunteer Research Opportunity

        My research lab actively investigates biological markers (endocrine and brain imaging) which may predict which women are at risk or who are "protected" from developing perinatal depression or anxiety. 

        I have worked with and trained several undergraduate, graduate and medical students in these research studies.

        The student's role, once CITI trained, is hands on with research participants under supervision.  Students learn about informed consent and perform depression screening in pregnant women and conduct visits on labor/delivery;  learn how research interviews are conducted which assess not only psychiatric symptoms but obstetric information; evaluate participants longitudinally from late pregnancy to the postpartum; learn about neuroendocrine biomarkers and their significance towards understanding the pathophysiology of perinatal depression; attend neuroimaging sessions at UMass Medical School, obtain collaborative skills with principal investigator (PI) and research coordinator involved in the study, perform minimal research database entry to be shared with PI and research coordinator, etc.  He/she will be able to learn about clinical trial design, recruitment strategies, research ethics, IRB procedures, etc. as they pertain to the study.  There are numerous facets in which to be involved, and the student would have a desk adjacent to the research coordinators in our research suite where the PI's office is within the CPRT research group.  The student would attend all research group meetings so that he/she would have exposure to the other studies ongoing in the CPRT research group.  Direct supervision would be by the PI for the entire research fellowship program.

        If you are interested in learning more, please contact Dr. Kristina Deligiannidis.



        Bibliographic 
        selected publications
        List All   |   Timeline
        1. Ostergaard SD, Fava M, Rothschild AJ, Deligiannidis KM. The implications of the National Institute of Mental Health Research Domain Criteria for researchers and clinicians. Acta Psychiatr Scand. 2014 Sep 9.
          View in: PubMed
        2. Wilkie GL, Deligiannidis KM. Effects of perinatal depression and anxiety on labor and delivery outcomes. Obstet Gynecol. 2014 May; 123 Suppl 1:82S-3S.
          View in: PubMed
        3. Babb JA, Deligiannidis KM, Murgatroyd CA, Nephew BC. Peripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures. Behav Brain Res. 2014 Apr 4.
          View in: PubMed
        4. Deligiannidis KM, Byatt N, Freeman MP. Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring. J Clin Psychopharmacol. 2014 Apr; 34(2):244-55.
          View in: PubMed
        5. Deligiannidis KM, Rothschild AJ, Barton BA, Kroll-Desrosiers AR, Meyers BS, Flint AJ, Whyte EM, Mulsant BH. A Gender Analysis of the Study of Pharmacotherapy of Psychotic Depression (STOP-PD): Gender and Age as Predictors of Response and Treatment-Associated Changes in Body Mass Index and Metabolic Measures. J Clin Psychiatry. 2013 Oct; 74(10):1003-9.
          View in: PubMed
        6. Smith EG, Deligiannidis KM, Ulbricht CM, Landolin CS, Patel JK, Rothschild AJ. Antidepressant Augmentation Using the N-Methyl-d-Aspartate Antagonist Memantine: A Randomized, Double-Blind, Placebo-Controlled Trial. J Clin Psychiatry. 2013 Oct; 74(10):966-73.
          View in: PubMed
        7. Deligiannidis KM, Freeman MP. Complementary and alternative medicine therapies for perinatal depression. Best Pract Res Clin Obstet Gynaecol. 2014 Jan; 28(1):85-95.
          View in: PubMed
        8. Deligiannidis KM, Sikoglu EM, Shaffer SA, Frederick B, Svenson AE, Kopoyan A, Kosma CA, Rothschild AJ, Moore CM. GABAergic neuroactive steroids and resting-state functional connectivity in postpartum depression: a preliminary study. J Psychiatr Res. 2013 Jun; 47(6):816-28.
          View in: PubMed
        9. Byatt N, Deligiannidis KM, Freeman MP. Antidepressant use in pregnancy: a critical review focused on risks and controversies. Acta Psychiatr Scand. 2013 Feb; 127(2):94-114.
          View in: PubMed
        10. Deligiannidis KM, Girgis RR, Lau A, Balon R, Zisook S. Psychiatry resident/fellow-initiated and -designed multi-modal psychopharmacology curriculum for major depression. Acad Psychiatry. 2012 Sep 1; 36(5):414-8.
          View in: PubMed
        11. Prabhakar D, Balon R, Deligiannidis, KM, Zisook S. . Revista de Trastornos del Ánimo. The American Society for Clinical Psychopharmacology’s Modules in Depression and Bipolar Disorder: Answering the Call for a Model Curriculum. 2011; 1(7):8-13.
        12. Moore Simas T, Byatt N, Deligiannidis KM. Alternative and Complementary Therapies. Clinical Roundup: How do you treat premenstrual syndrome in your practice?. 2011; 17(4):237.
        13. Deligiannidis KM. Psychiatry Issue Briefs. Depression in women during childbearing years: causes, symptoms, challenges and treatment. 2011; 8(1).
        14. Deligiannidis KM, Freeman MP. Complementary and alternative medicine for the treatment of depressive disorders in women. Psychiatr Clin North Am. 2010 Jun; 33(2):441-63.
          View in: PubMed
        15. Deligiannidis KM. Therapeutic drug monitoring in pregnant and postpartum women: recommendations for SSRIs, lamotrigine, and lithium. J Clin Psychiatry. 2010 May; 71(5):649-50.
          View in: PubMed
        16. Marsh WK, Deligiannidis KM. Current Psychiatry. Sex-related differences in antidepressant response: When to adjust treatment. 2010; 9(5):25-30.
        17. Meyers BS, Flint AJ, Rothschild AJ, Mulsant BH, Whyte EM, Peasley-Miklus C, Papademetriou E, Leon AC, Heo M. A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD). Arch Gen Psychiatry. 2009 Aug; 66(8):838-47.
          View in: PubMed
        18. Falcón J, Galarneau KM, Weller JL, Ron B, Chen G, Coon SL, Klein DC. Regulation of arylalkylamine N-acetyltransferase-2 (AANAT2, EC 2.3.1.87) in the fish pineal organ: evidence for a role of proteasomal proteolysis. Endocrinology. 2001 May; 142(5):1804-13.
          View in: PubMed
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