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    Last Name

    Kristina M Deligiannidis MD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    AddressUniversity of Massachusetts Medical School
    328 Shrewsbury Street
    Worcester MA 01604
      Other Positions
      InstitutionUMMS - School of Medicine
      DepartmentObstetrics and Gynecology

        awards and honors
        NIH, NICHD, Program in Developmental Endocrinology and Genetics/Section on Neuroendocrinology1996Summer Intramural Research Training Award
        University of Massachusetts -Amherst1997Commonwealth Scholar
        NIH, NICHD, Program in Developmental Endocrinology and Genetics/Section on Neuroendocrinology1998 - 2000Predoctoral Intramural Research Training Award
        University of Massachusetts Medical School2003 - 2004Charles J. Hoff Scholar
        2004T. Byram Karasu Award in Psychotherapy for Medical Students
        2007 - 2008American Society of Clinical Psychopharmacology/NIMH Clinical Trials in Psychopharmacology Awards
        American Psychiatric Association & APIRE2008 - 2009APA/APIRE Junior Investigator Awards
        University of Massachusetts Medical School2009Paul F. Briscoli Award for Resident-Faculty Academic Collaboration
        University of Massachusetts Medical School2009Resident Educator Award
        NIH, NIMH, Experimental Therapeutics & Pathophysiology Branch and Behavioral Endocrinology Branc2009Residents Elective Program in Clinical Research
        American Society for Clinical Psychopharmacology2009NIMH/NCDEU New Investigator Award
        2010Worcester Foundation for Biomedical Research Grant
        2011Society for Biological Psychiatry (SOBP) Travel Scholarship Award
        UMass Medical School, Dept of Psychiatry2011Career Development and Research Office Research Fellowship Award
        UMass Medical School, Office of Faculty Affairs2011Faculty Scholar Award
        UMass Medical School- CCTS- CTSA2011 - 2013Center for Clinical and Translational Science Pilot Project Program Grant
        University of Massachusetts Medical School; Dept of Psychiatry2012Faculty Teaching Award for Outstanding Resident Teaching
        University of Pittsburgh/Stanford University2012 - 2014Career Development Institute (CDI) for Psychiatry Award (NIMH R25MH090947)
        NIH, NIMH2013 - 2018NIH K23 Career Development Award
        University of Massachusetts Medical School2013Early Career Achievement in Science and Health Award
        2013Best Doctors in America
        2013National Network of Depression Centers Annual Scientific Conference Travel Award
        American College of Neuropsychopharmacology2014ACNP Travel Award
        NIH, NIMH2014 - 2016NIH Clinical Research Loan Repayment Program Award
        NIH, Center for Scientific Review2014NIH Early Career Reviewer


        Dr. Deligiannidis completed her undergraduate degrees and an Honors Scholars Research Program in Neuroscience and Behavior at the University of Massachusetts at Amherst.  As a recipient of NIH pre-doctoral Intramural Research Training Awards, she trained in molecular neuroendocrinology research at the NIH/National Institutes of Child Health and Human Development (NIH/NICHD). 

        Dr. Deligiannidis completed additional research training at the National Institute of Mental Health (NIMH) and NICHD during medical school and residency.  She received her medical degree from the University of Massachusetts Medical School and completed her psychiatry residency and chief residency in psychopharmacology research at UMass Medical School (UMMS)/UMass Memorial Health Care (UMMHC).  Dr. Deligiannidis joined faculty at UMMS in October 2009 as an Assistant Professor of Psychiatry and is Board Certified by the American Board of Psychiatry and Neurology.

        Dr. Deligiannidis is the Director of the Depression Specialty Clinic, a regional referral center at UMMHC that specializes in the evaluation and treatment of adult patients suffering from major depression, psychotic depression, treatment-resistant depression and bipolar depression.

        Dr. Deligiannidis also evaluates and treats women in the Women’s Mental Health Specialty Clinic at UMMHC.  She provides consultation and short-term treatment of women suffering from depression and anxiety during pregnancy or the post-partum period. Her expertise is focused on psychopharmacologic complementary/alternative treatments for depression/anxiety/stress during the perinatal period.

        Dr. Deligiannidis conducts translational research in the causes of perinatal depression.  She also conducts depression research on novel therapeutics.  Her research interests include:

        • Psychoneuroendocrinology (hypothalamic-pituitary-adrenal and gonadal axes, gonadal hormones and neuroactive steroids)
        • Neuroimaging and neuroendocrine biomarkers of depression in women during perinatal period
        • Gender differences in depression and treatment response
        • Neuroimaging  (MRS, fMRI, PET)
        • Complementary and alternative/integrative treatments

        Dr. Deligiannidis's research efforts have been nationally recognized.  She is the recipient of: a 2014 ACNP (American College of Neuropsychopharmacology) Travel Award; 2013-2018 NIH K23 Career Development Award, 2014-2016 NIH LRP Award, 2012 Research Career Development Institute (CDI) for Psychiatry Award (University of Pittsburgh/Stanford University), 2011 UMass Medical School Center for Clinical & Translational Science (CTSA) Pilot Grant, a UMMS Faculty Scholar Award, a 2011 Society for Biological Psychiatry Travel Scholarship Award, a 2010 Worcester Foundation for Biomedical Research Grant; a 2009 NIMH/NCDEU New Investigator Award, APA/APIRE Junior Investigator Awards (2008, 2009) and American Society of Clinical Psychopharmacology/NIMH Clinical Trials in Psychopharmacology Awards (2007, 2008).  At UMass, she has received the Early Career Achievement Award in Science and Health (2013) and several teaching awards.

        Dr. Deligiannidis actively participates in national scientific committees and gives scientific presentations locally, regionally and nationally.  She is an appointed Young Investigator Member of the International Society of Psychoneuroendocrinology (ISPNE) and a member of the Society of Biological Psychiatry (SOBP), the Society of Behavioral Neuroendocrinology (SBE), the Organization for Human Brain Mapping (OHBM), and the American Society of Clinical Psychopharmacology (ASCP).  She serves on the Board of Directors of ASCP and on the Editorial Board for the international journal, Acta Psychiatrica Scandinavica, Co-Chair of the Education Committees for both the ASCP and SOBP and is an Early Career Reviewer at NIH.

        Rotation Projects

        University of Massachusetts Medical School Summer Research Program for Medical Students

        If interested, please contact Dr. Kristina Deligiannidis and read description below.

        University of Massachusetts Medical School Senior Scholars Project

        If interested, please contact Dr. Kristina Deligiannidis to discuss research project ideas.

        University of Massachusetts Medical School Volunteer Research Opportunity

        My research lab actively investigates biological markers (endocrine and brain imaging) which may predict which women are at risk or who are "protected" from developing perinatal depression or anxiety. 

        I have worked with and trained several undergraduate, graduate and medical students in these research studies.

        The student's role, once CITI trained, is hands on with research participants under supervision.  Students learn about informed consent and perform depression screening in pregnant women and conduct visits on labor/delivery;  learn how research interviews are conducted which assess not only psychiatric symptoms but obstetric information; evaluate participants longitudinally from late pregnancy to the postpartum; learn about neuroendocrine biomarkers and their significance towards understanding the pathophysiology of perinatal depression; attend neuroimaging sessions at UMass Medical School, obtain collaborative skills with principal investigator (PI) and research coordinator involved in the study, perform minimal research database entry to be shared with PI and research coordinator, etc.  He/she will be able to learn about clinical trial design, recruitment strategies, research ethics, IRB procedures, etc. as they pertain to the study.  There are numerous facets in which to be involved, and the student would have a desk adjacent to the research coordinators in our research suite where the PI's office is within the CPRT research group.  The student would attend all research group meetings so that he/she would have exposure to the other studies ongoing in the CPRT research group.  Direct supervision would be by the PI for the entire research fellowship program.

        If you are interested in learning more, please contact Dr. Kristina Deligiannidis.

        selected publications
        List All   |   Timeline
        1. Ostergaard SD, Fava M, Rothschild AJ, Deligiannidis KM. The implications of the National Institute of Mental Health Research Domain Criteria for researchers and clinicians. Acta Psychiatr Scand. 2014 Sep 9.
          View in: PubMed
        2. Wilkie GL, Deligiannidis KM. Effects of perinatal depression and anxiety on labor and delivery outcomes. Obstet Gynecol. 2014 May; 123 Suppl 1:82S-3S.
          View in: PubMed
        3. Babb JA, Deligiannidis KM, Murgatroyd CA, Nephew BC. Peripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures. Behav Brain Res. 2014 Apr 4.
          View in: PubMed
        4. Deligiannidis KM, Byatt N, Freeman MP. Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring. J Clin Psychopharmacol. 2014 Apr; 34(2):244-55.
          View in: PubMed
        5. Deligiannidis KM, Rothschild AJ, Barton BA, Kroll-Desrosiers AR, Meyers BS, Flint AJ, Whyte EM, Mulsant BH. A Gender Analysis of the Study of Pharmacotherapy of Psychotic Depression (STOP-PD): Gender and Age as Predictors of Response and Treatment-Associated Changes in Body Mass Index and Metabolic Measures. J Clin Psychiatry. 2013 Oct; 74(10):1003-9.
          View in: PubMed
        6. Smith EG, Deligiannidis KM, Ulbricht CM, Landolin CS, Patel JK, Rothschild AJ. Antidepressant Augmentation Using the N-Methyl-d-Aspartate Antagonist Memantine: A Randomized, Double-Blind, Placebo-Controlled Trial. J Clin Psychiatry. 2013 Oct; 74(10):966-73.
          View in: PubMed
        7. Deligiannidis KM, Freeman MP. Complementary and alternative medicine therapies for perinatal depression. Best Pract Res Clin Obstet Gynaecol. 2014 Jan; 28(1):85-95.
          View in: PubMed
        8. Deligiannidis KM, Sikoglu EM, Shaffer SA, Frederick B, Svenson AE, Kopoyan A, Kosma CA, Rothschild AJ, Moore CM. GABAergic neuroactive steroids and resting-state functional connectivity in postpartum depression: a preliminary study. J Psychiatr Res. 2013 Jun; 47(6):816-28.
          View in: PubMed
        9. Byatt N, Deligiannidis KM, Freeman MP. Antidepressant use in pregnancy: a critical review focused on risks and controversies. Acta Psychiatr Scand. 2013 Feb; 127(2):94-114.
          View in: PubMed
        10. Deligiannidis KM, Girgis RR, Lau A, Balon R, Zisook S. Psychiatry resident/fellow-initiated and -designed multi-modal psychopharmacology curriculum for major depression. Acad Psychiatry. 2012 Sep 1; 36(5):414-8.
          View in: PubMed
        11. Prabhakar D, Balon R, Deligiannidis, KM, Zisook S. . Revista de Trastornos del Ánimo. The American Society for Clinical Psychopharmacology’s Modules in Depression and Bipolar Disorder: Answering the Call for a Model Curriculum. 2011; 1(7):8-13.
        12. Moore Simas T, Byatt N, Deligiannidis KM. Alternative and Complementary Therapies. Clinical Roundup: How do you treat premenstrual syndrome in your practice?. 2011; 17(4):237.
        13. Deligiannidis KM. Psychiatry Issue Briefs. Depression in women during childbearing years: causes, symptoms, challenges and treatment. 2011; 8(1).
        14. Deligiannidis KM, Freeman MP. Complementary and alternative medicine for the treatment of depressive disorders in women. Psychiatr Clin North Am. 2010 Jun; 33(2):441-63.
          View in: PubMed
        15. Deligiannidis KM. Therapeutic drug monitoring in pregnant and postpartum women: recommendations for SSRIs, lamotrigine, and lithium. J Clin Psychiatry. 2010 May; 71(5):649-50.
          View in: PubMed
        16. Marsh WK, Deligiannidis KM. Current Psychiatry. Sex-related differences in antidepressant response: When to adjust treatment. 2010; 9(5):25-30.
        17. Meyers BS, Flint AJ, Rothschild AJ, Mulsant BH, Whyte EM, Peasley-Miklus C, Papademetriou E, Leon AC, Heo M. A double-blind randomized controlled trial of olanzapine plus sertraline vs olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD). Arch Gen Psychiatry. 2009 Aug; 66(8):838-47.
          View in: PubMed
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