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    John L Sullivan MD

    TitleProfessor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentPediatrics
    AddressUniversity of Massachusetts Medical School
    373 Plantation Street
    Worcester MA 01605
    Phone508-856-1638
      Other Positions
      InstitutionUMMS - School of Medicine
      DepartmentMicrobiology and Physiological Systems

      InstitutionUMMS - School of Medicine
      DepartmentPathology

      InstitutionUMMS - School of Medicine
      DepartmentProgram in Molecular Medicine

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentClinical Population Health Research

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentImmunology and Virology

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentInterdisciplinary Graduate Program

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentMasters in Clinical Investigation

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentMolecular Genetics and Microbiology

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentTranslational Science

      InstitutionUMMS - Programs, Centers and Institutes
      DepartmentCenter for AIDS Research

        Overview 
        Narrative

        Academic Background

        John L. Sullivan received his BS from LeMoyne College in 1968 and his MD from SUNY Upstate Medical School, Syracuse, in 1972. From 1973 to 1975, he served as a staff associate in the Division of Virology at the NIH Bureau of Biologics in Bethesda, Maryland. He completed his pediatric training and clinical immunology at the University of Washington. In 1978, he joined the Department of Pediatrics at the University of Massachusetts Medical School. In 1984 the American Heart Association awarded him an Established Investigatorship. Dr. Sullivan served on the Immunological Sciences Study Section 1982-1986 and was a Charter Member of AIDS and Related Research Study Section (1990-92) of the NIH.

        Epstein-Barr Virus [EBV] and Human Immunodeficiency Virus [HIV]

        John L. Sullivan, MDResearch in this laboratory is aimed at understandingthe pathogenesis of chronic infection with Epstein-Barr Virus [EBV] and Human Immunodeficiency Virus [HIV]. Studies of EBV are focused on the nature of the immune response which controls but does not eradicate viral replication and the nature of the immune defect which results in the X-linked lymphoproliferative syndrome. Studies of HIV are focused on the elucidation and characterization of HIV gene mutations which result in infections associated with long term control of viral replication and/or lack of disease progression.

        Experimental therapeutic and preventative vaccine approaches are also being studied. These include combination antiretroviral agents to interrupt viral replication and recombinant vector or live attenuated vaccines to prevent HIV-1 infection. Of particular interest is the development of therapeutics and vaccine regimens which can be used in the developing world to interrupt maternal to child transmission.



        Rotation Projects

        Potential Rotation Projects

        Contact Dr. Sullivan for more project details.



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