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    Jan Cerny MD, PhD

    TitleAssistant Professor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentMedicine
    AddressUniversity of Massachusetts Medical School
    55 Lake Avenue North
    Worcester MA 01655
    Phone774-442-3903
        Bibliographic 
        selected publications
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        1. Devitt K, Cerny J, Switzer B, Ramanathan M, Nath R, Yu H, Woda BA, Chen BJ. Hemophagocytic lymphohistiocytosis secondary to T-cell/histiocyte-rich large B-cell lymphoma. Leuk Res Rep. 2014; 3(2):42-5.
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        2. Xiao R, Cerny J, Devitt K, Dresser K, Nath R, Ramanathan M, Rodig SJ, Chen BJ, Woda BA, Yu H. MYC Protein Expression Is Detected in Plasma Cell Myeloma but Not in Monoclonal Gammopathy of Undetermined Significance (MGUS). Am J Surg Pathol. 2014 Jun; 38(6):776-83.
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        3. Cerny J, Yu H, Miron PM. Novel FGFR3 rearrangement t(4;22)(p16;q11.2) in a patient with chronic lymphocytic leukemia/small lymphocytic lymphoma. Ann Hematol. 2013 Oct; 92(10):1433-5.
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        4. Ramanathan M, Cerny J, Yu H, Woda BA, Nath R. A combination treatment approach and cord blood stem cell transplant for blastic plasmacytoid dendritic cell neoplasm. Haematologica. 2013 Mar; 98(3):e36.
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        5. Cerny J, Yu H, Ramanathan M, Raffel GD, Walsh WV, Fortier N, Shanahan L, O'Rourke E, Bednarik J, Barton B, Kroll-Desrosiers A, Hao S, Woda B, Hutchinson L, Evens AM, Rosmarin AG, Nath R. Expression of CD25 independently predicts early treatment failure of acute myeloid leukaemia (AML). Br J Haematol. 2013 Jan; 160(2):262-6.
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        6. Zhang H, Peng C, Hu Y, Li H, Sheng Z, Chen Y, Sullivan C, Cerny J, Hutchinson L, Higgins A, Miron P, Zhang X, Brehm MA, Li D, Green MR, Li S. The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells. Nat Genet. 2012 Aug; 44(8):861-71.
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        7. Cerny J, Rosmarin AG. Why does my patient have leukocytosis? Hematol Oncol Clin North Am. 2012 Apr; 26(2):303-19, viii.
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        8. Shi M, Miron PM, Hutchinson L, Woda BA, Nath R, Cerny J, Yu H. Anaplastic lymphoma kinase-positive large B-cell lymphoma with complex karyotype and novel ALK gene rearrangements. Hum Pathol. 2011 Oct; 42(10):1562-7.
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        9. Ramanthan M, Cerny J, Nath R. Sorafenib skin toxicity post transplant. Blood. 2011.
        10. Houghton J, Li H, Fan X, Liu Y, Liu JH, Rao VP, Poutahidis T, Taylor CL, Jackson EA, Hewes C, Lyle S, Cerny A, Bowen G, Cerny J, Moore N, Kurt-Jones EA, Erdman SE. Mutations in bone marrow-derived stromal stem cells unmask latent malignancy. Stem Cells Dev. 2010 Aug; 19(8):1153-66.
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        11. Cerny J, Trneny M, Slavickova A, Pytlik R, Salkova J, Valkova V, Liu Q, Houghton J, Klener P. Rituximab based therapy followed by autologous stem cell transplantation leads to superior outcome and high rates of PCR negativity in patients with indolent B-cell lymphoproliferative disorders. Hematology. 2009 Aug; 14(4):187-97.
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        12. Truong F, Smith BR, Stachurski D, Cerny J, Medeiros LJ, Woda BA, Wang SA. The utility of flow cytometric immunophenotyping in cytopenic patients with a non-diagnostic bone marrow: a prospective study. Leuk Res. 2009 Aug; 33(8):1039-46.
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        13. Cerny J, Hassan A, Smith C, Piperdi B. Coronary vasospasm with myocardial stunning in a patient with colon cancer receiving adjuvant chemotherapy with FOLFOX regimen. Clin Colorectal Cancer. 2009 Jan; 8(1):55-8.
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        14. Cerny J, Wang S, Miron P, Hutchinson L, Brettler D. EBV-negative Hodgkin lymphoma in ZAP-70-positive B-cell lymphocytic leukemia patient. Ann Hematol. 2009 May; 88(5):495-7.
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        15. Cerny J, Licho R, Simkin P, Walsh WV. Hypertrophic pulmonary osteoarthropathy disappearance despite lung cancer relapse. South Med J. 2008 Sep; 101(9):970-1.
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        16. Cerny J, Fadare O, Hutchinson L, Wang SA. Clinicopathological features of extramedullary recurrence/relapse of multiple myeloma. Eur J Haematol. 2008 Jul; 81(1):65-9.
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        17. Colvin GA, Lambert JF, Dooner MS, Cerny J, Quesenberry PJ. Murine allogeneic in vivo stem cell homing(,). J Cell Physiol. 2007 May; 211(2):386-91.
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        18. Galili N, Cerny J, Raza A. Current treatment options: impact of cytogenetics on the course of myelodysplasia. Curr Treat Options Oncol. 2007 Apr; 8(2):117-28.
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        19. Wang SA, Galili N, Cerny J, Sechman E, Chen SS, Loew J, Liu Q, Fadare O, Hasserjian R, Jones D, Qawi H, Woda B, Raza A. Chronic myelomonocytic leukemia evolving from preexisting myelodysplasia shares many features with de novo disease. Am J Clin Pathol. 2006 Nov; 126(5):789-97.
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        20. Galili N, Sechman EV, Cerny J, Mehdi M, Mumtaz M, Westervelt P, Maguire J, Raza A. Clinical response of myelodysplastic syndromes patients to treatment with coenzyme Q10. Leuk Res. 2007 Jan; 31(1):19-26.
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        21. Chang H, Cerny J. Molecular characterization of chronic lymphocytic leukemia with two distinct cell populations: Evidence for separate clonal origins. Am J Clin Pathol. 2006 Jul; 126(1):23-8.
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        22. Slavícková A, Forsterová K, Ivánek R, Cerný J, Klener P. The use of comparative duplex PCR in monitoring of patients with non-Hodgkin's lymphoma and chronic lymphocytic leukaemia. Folia Biol (Praha). 2005; 51(6):177-9.
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        23. Cerny J, Quesenberry PJ. Chromatin remodeling and stem cell theory of relativity. J Cell Physiol. 2004 Oct; 201(1):1-16.
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        24. Cerny J, Slavickova A, Krepelova A, Trneny M, Karban J, Klener P. Biallelic IgH rearrangements in patients with indolent lymphoproliferative disorders: molecular and practical implications. J Cell Physiol. 2004 May; 199(2):217-26.
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        25. Colvin GA, Lambert JF, Moore BE, Carlson JE, Dooner MS, Abedi M, Cerny J, Quesenberry PJ. Intrinsic hematopoietic stem cell/progenitor plasticity: Inversions. J Cell Physiol. 2004 Apr; 199(1):20-31.
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        26. Colvin GA, Lambert JF, Abedi M, Dooner MS, Demers D, Moore BE, Greer D, Aliotta JM, Pimentel J, Cerny J, Lum LG, Quesenberry PJ. Differentiation hotspots: the deterioration of hierarchy and stochasm. Blood Cells Mol Dis. 2004 Jan-Feb; 32(1):34-41.
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        27. Dooner M, Cerny J, Colvin G, Demers D, Pimentel J, Greer D, Abedi M, McAuliffe C, Quesenberry P. Homing and conversion of murine hematopoietic stem cells to lung. Blood Cells Mol Dis. 2004 Jan-Feb; 32(1):47-51.
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        28. Bertho N, Cerny J, Kim YM, Fiebiger E, Ploegh H, Boes M. Requirements for T cell-polarized tubulation of class II+ compartments in dendritic cells. J Immunol. 2003 Dec 1; 171(11):5689-96.
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        29. Cerny J, Slavickova A, Krepelova A, Trneny M, Karban J, Klener P. Familial chronic lymphocytic leukemia. Haematologica. 2003 Oct; 88(10):1190-1.
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        30. Song E, Lee SK, Dykxhoorn DM, Novina C, Zhang D, Crawford K, Cerny J, Sharp PA, Lieberman J, Manjunath N, Shankar P. Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J Virol. 2003 Jul; 77(13):7174-81.
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        31. Cerny J, Slavickova A, Krepelova A, Trneny M, Karban J, Klener P. Unusual sequence of VDJ rearrangement revealed by molecular analysis in a patient with indolent lymphoma. Haematologica. 2003 May; 88(5):ECR15.
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        32. Cerny J, Slavickova A, Krepelova A, Trneny M, Klener P. Chemotherapy alone may lead to a PCR negative stem cell harvest in transformed lymphoma refractory to rituximab. Haematologica. 2003 Mar; 88(3):ECR06.
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        33. Cerny J, Dooner M, McAuliffe C, Habibian H, Stencil K, Berrios V, Reilly J, Carlson J, Cerny AM, d'Hondt L, Benoit B, Lambert JF, Colvin G, Nilsson S, Becker P, Quesenberry P. Homing of purified murine lymphohematopoietic stem cells: a cytokine-induced defect. J Hematother Stem Cell Res. 2002 Dec; 11(6):913-22.
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        34. D'Hondt L, Lambert JF, Damon J, Benoit BO, Cerny J, Carlson JE, Reilly J, Wuu J, Colvin GA, Dooner MS, Quesenberry PJ. Engraftment of post 5-fluorouracil murine marrow into minimally myeloablated (100 cGy) murine hosts. J Hematother Stem Cell Res. 2002 Jun; 11(3):483-90.
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        35. Ballen K, Becker PS, Greiner D, Valinski H, Shearin D, Berrios V, Dooner G, Hsieh CC, Wuu J, Shultz L, Cerny J, Leif J, Stewart FM, Quesenberry P. Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD-scid mice. Br J Haematol. 2000 Mar; 108(3):629-40.
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