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    Last Name

    Patricia D Franklin MD, MBA, MPH

    InstitutionUniversity of Massachusetts Medical School
    DepartmentOrthopedics and Physical Rehabilitation
    AddressUniversity of Massachusetts Medical School
    55 Lake Avenue North
    Worcester MA 01655
      Other Positions
      InstitutionUMMS - School of Medicine
      DepartmentFamily Medicine and Community Health

      InstitutionUMMS - School of Medicine
      DepartmentQuantitative Health Sciences

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentClinical Population Health Research

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentMD/PhD Program



        College of the Holy Cross, AB, 1979
        University of Rochester School of Medicine, MD, 1983
        MBA University of Rochester, Simon School, 1986
        MPH University of Rochester School of Medicine, 1989
        Residency, General Preventive Medicine
        Fellowship, Health Services Research and Administration

        Research Focus

        • Biopsychosocial predictors of functional outcome, cost, and utilization in chronic musculoskeletal conditions.
        • Role of physical activity and self-care in functional outcome.
        • eHealth interventions to support self-care and tertiary prevention in aging, chronic disease populations.

        Link to Patricia Franklin's research page

        Grant Funding

        "Comparative effectiveness of pulmonary embolism prevention after hip and knee replacement (PEPPER); balancing safery and efficacy" (Subaward)
        Sponsor: PCORI
        Patricia Franklin, Principal Investigator; David Ayers, CO-Investigator 

        "Creating national surveillance infrastructure for prority medical devices" 
        Sponsor: FDA
        Patricia Franklin, Principal Investigator; Hua Zheng, CO-Investigator

        "TJR Guru: mobile app for shared informed decision making in total joint replacement surgery" 
        Sponsor: AHRQ 
        Hua Zheng, Principal Investigator; Patricia Franklin, CO-Principal Investigator

        "Improving Orthopedic Outcomes Through a National TJR Registry" 
        Sponsor: NIH-Agency for Healthcare Research and Quality (AHRQ) 
        Patricia Franklin, Principal Investigator; David Ayers, CO-Investigator; Paul Fanning, CO-Investigator; Wenjun Li, CO-Investigator

        In Fall 2010, the Agency for Healthcare Research and Quality (AHRQ) awarded $12 million to the University of Massachusetts Department of Orthopedics and Physical Rehabilitation to develop and implement FORCE-TJR, a nationwide, comprehensive database of total joint replacement (TJR) surgical and patient-reported outcomes. The FORCE-TJR research effort is collecting data from more than 25,000 TJR patients, using tools with which to record the patients’ assessment of the success and failure of their surgery, and is conducting research to guide both clinical care and health care policy.  Link to FORCE-TJR website

        "Perioperative intervention to improve post-TKR support and function"
        Sponsor: NIAMS
        Patricia Franklin, Principal Investigator; Milagros Rosal, CO-Investigator; David Ayers, CO-Investigator; Wenjun Li, CO-Investigator

        This research develops and tests a patient-centered telephone counselor support intervention to enhance self-efficacy, self-care, and adherence to physical activity in the rehabilitation period. As the population ages, maintenance and improvement of independent physical function will have increased importance to osteoarthritis patients and society. Thus, new health delivery models that integrate behavioral care with rehabilitation are needed.

        "eHealth tools for knee arthritis patients: treatment choice, outcome assessment, and answers: how will I benefit from total knee replacement surgery?"
        Sponsor: Robert Wood Johnson Foundation
        Patricia Franklin, Principal Investigator; Wenjun Li, CO-Investigator; David Ayers, CO-Investigator

        Using an existing national registry of more than 8,300 TKR patients the proposed eHealth tools will translate quality measurement data to individualized, evidence-based outcome predictions to guide patients TKR decisions.

        "A New Technology to Preserve Patient Privacy and Data Quality in Health Research"
        Sponsor: UMass Lowell
        Patricia Franklin, Principal Investigator; Wenjun Li, CO-Investigator

        "Patient Outcomes Registry for Clinical and Translational Research"
        Sponsor: UMMHC
        David Ayers, CO-Principal Investigator; Patricia Franklin, CO-Principal Investigator

        "Define implant-related efficiencies and develop software to estimate hospital benefits and costs for the Zimmer Patient Specific Instruments (PSI)"
        Sponsor: Zimmer, Inc.
        David Ayers, Principal Investigator; Patricia Franklin, CO-Investigator

        "Technology to Assess Physical Activity and Sedentary Behavior in Aging Adults with Osteoarthritis"
        Sponsor: UMass Life Science Moment Fund (LSMF) Awards
        Patricia Franklin, Principal Investigator; Wenjun Li, CO-Investigator

        Rotation Projects

        Research Rotations

        1. Understanding the role of patient attributes and post-operative activity on long-term functional outcome following Total Joint Replacement. The Center for Arthritis and Total Joint Replacement is conducting a series of clinical and outcomes studies evaluating the roles of pre-operative emotional health, co-existing illness, and post-operative rehabilitation exercise adherence on level of post-operative improvement in long-term physical function. For example, a randomized trial of a behaviorally-based, post-surgical exercise and activity program will evaluate patient adherence and long-term physical function.
        2. Predictors of functional outcome in chronic degenerative conditions of the spine and wrist.
          Longitudinal studies are evaluating the contribution of patient attributes, emotional support, and co-existing conditions to predicting pain and function in operative and non-operative care of patients with lumbar stenosis and carpal tunnel syndrome.
        3. Email and web-based health promotion programs for arthritis and primary prevention. Health promotion via sequential emails and interactive web-based tools is currently being evaluated in a worksite randomized trial. The program is designed to enhance adoption of healthy diets and physical activity. Health-related work productivity and health costs will be evaluated. A multi-component web-based arthritis education program will extrapolate the lessons learned to arthritis self-care.

        Additional information about lab rotations within the CPHR program can be found at

        selected publications
        List All   |   Timeline
        1. Rolfson O, Bohm E, Franklin P, Lyman S, Denissen G, Dawson J, Dunn J, Eresian Chenok K, Dunbar M, Overgaard S, Garellick G, Lübbeke A. Patient-reported outcome measures in arthroplasty registries Report of the Patient-Reported Outcome Measures Working Group of the International Society of Arthroplasty Registries Part II. Recommendations for selection, administration, and analysis. Acta Orthop. 2016 Jul; 87 Suppl 1:9-23.
          View in: PubMed
        2. Rolfson O, Eresian Chenok K, Bohm E, Lübbeke A, Denissen G, Dunn J, Lyman S, Franklin P, Dunbar M, Overgaard S, Garellick G, Dawson J. Patient-reported outcome measures in arthroplasty registries. Acta Orthop. 2016 Jul; 87 Suppl 1:3-8.
          View in: PubMed
        3. Lavallee DC, Chenok KE, Love RM, Petersen C, Holve E, Segal CD, Franklin PD. Incorporating Patient-Reported Outcomes Into Health Care To Engage Patients And Enhance Care. Health Aff (Millwood). 2016 Apr; 35(4):575-82.
          View in: PubMed
        4. Lyman S, Lee YY, Franklin PD, Li W, Mayman DJ, Padgett DE. Validation of the HOOS, JR: A Short-form Hip Replacement Survey. Clin Orthop Relat Res. 2016 Jun; 474(6):1472-82.
          View in: PubMed
        5. Lyman S, Lee YY, Franklin PD, Li W, Cross MB, Padgett DE. Validation of the KOOS, JR: A Short-form Knee Arthroplasty Outcomes Survey. Clin Orthop Relat Res. 2016 Jun; 474(6):1461-71.
          View in: PubMed
        6. Chimenti PC, Drinkwater CJ, Li W, Lemay CA, Franklin PD, O'Keefe RJ. Factors Associated With Early Improvement in Low Back Pain After Total Hip Arthroplasty: A Multi-Center Prospective Cohort Analyses. J Arthroplasty. 2016 Jan; 31(1):176-9.
          View in: PubMed
        7. Ayers DC, Fehring TK, Odum SM, Franklin PD. Using joint registry data from FORCE-TJR to improve the accuracy of risk-adjustment prediction models for thirty-day readmission after total hip replacement and total knee replacement. J Bone Joint Surg Am. 2015 Apr 15; 97(8):668-71.
          View in: PubMed
        8. Franklin P, Nguyen U, Ayers D, Weissman N. Improving the criteria for appropriateness of total joint replacement surgery: comment on the article by Riddle et Al. Arthritis Rheumatol. 2015 Feb; 67(2):585.
          View in: PubMed
        9. Ayers DC, Li W, Harrold L, Allison J, Franklin PD. Preoperative pain and function profiles reflect consistent TKA patient selection among US surgeons. Clin Orthop Relat Res. 2015 Jan; 473(1):76-81.
          View in: PubMed
        10. Zheng H, Li W, Harrold L, Ayers DC, Franklin PD. Web-based Comparative Patient-reported Outcome Feedback to Support Quality Improvement and Comparative Effectiveness Research in Total Joint Replacement. EGEMS (Wash DC). 2014; 2(1):1130.
          View in: PubMed
        11. Franklin PD, Lewallen D, Bozic K, Hallstrom B, Jiranek W, Ayers DC. Implementation of patient-reported outcome measures in U.S. Total joint replacement registries: rationale, status, and plans. J Bone Joint Surg Am. 2014 Dec 17; 96 Suppl 1:104-9.
          View in: PubMed
        12. Ayers DC, Li W, Harrold L, Allison J, Franklin PD. Reply to the letter to the editor: preoperative pain and function profiles reflect consistent TKA patient selection among US surgeons. Clin Orthop Relat Res. 2015 Jan; 473(1):395-6.
          View in: PubMed
        13. Harrold L, Pascal S, Lewis C, O'Keefe R, Pellegrini V, Allison J, Ayers D, Franklin P. Patient report improves posthospital discharge event capture in total joint replacement: a novel approach to capturing all posthospital event data. EGEMS (Wash DC). 2014; 2(1):1107.
          View in: PubMed
        14. Ayers DC, Franklin PD. Joint replacement registries in the United States: a new paradigm. J Bone Joint Surg Am. 2014 Sep 17; 96(18):1567-9.
          View in: PubMed
        15. Ayers D, Franklin P. Improve care through outcomes reporting. Mod Healthc. 2013 Dec 2; 43(48):34.
          View in: PubMed
        16. Ayers DC, Franklin PD, Ring DC. The role of emotional health in functional outcomes after orthopaedic surgery: extending the biopsychosocial model to orthopaedics: AOA critical issues. J Bone Joint Surg Am. 2013 Nov 6; 95(21):e165.
          View in: PubMed
        17. Franklin PD, Harrold L, Ayers DC. Incorporating patient-reported outcomes in total joint arthroplasty registries: challenges and opportunities. Clin Orthop Relat Res. 2013 Nov; 471(11):3482-8.
          View in: PubMed
        18. Ayers DC, Zheng H, Franklin PD. Integrating patient-reported outcomes into orthopaedic clinical practice: proof of concept from FORCE-TJR. Clin Orthop Relat Res. 2013 Nov; 471(11):3419-25.
          View in: PubMed
        19. Ayers DC, Li W, Oatis C, Rosal MC, Franklin PD. Patient-reported outcomes after total knee replacement vary on the basis of preoperative coexisting disease in the lumbar spine and other nonoperatively treated joints: the need for a musculoskeletal comorbidity index. J Bone Joint Surg Am. 2013 Oct 16; 95(20):1833-7.
          View in: PubMed
        20. Franklin PD, Rosal MC. Can knee arthroplasty play a role in weight management in knee osteoarthritis? Arthritis Care Res (Hoboken). 2013 May; 65(5):667-8.
          View in: PubMed
        21. Zheng H, Rosal MC, Oatis CA, Li W, Franklin PD. Tailored system to deliver behavioral intervention and manage data in randomized trials. J Med Internet Res. 2013; 15(4):e58.
          View in: PubMed
        22. Ibrahim SA, Franklin PD. Race and elective joint replacement: where a disparity meets patient preference. Am J Public Health. 2013 Apr; 103(4):583-4.
          View in: PubMed
        23. Franklin PD, Allison JJ, Ayers DC. Beyond joint implant registries: a patient-centered research consortium for comparative effectiveness in total joint replacement. JAMA. 2012 Sep 26; 308(12):1217-8.
          View in: PubMed
        24. Briggs VG, Li W, Kaplan MS, Eskander MS, Franklin PD. Injection treatment and back pain associated with degenerative lumbar spinal stenosis in older adults. Pain Physician. 2010 Nov-Dec; 13(6):E347-55.
          View in: PubMed
        25. Eskander MS, Drew JM, Aubin ME, Marvin J, Franklin PD, Eck JC, Patel N, Boyle K, Connolly PJ. Vertebral artery anatomy: a review of two hundred fifty magnetic resonance imaging scans. Spine (Phila Pa 1976). 2010 Nov 1; 35(23):2035-40.
          View in: PubMed
        26. Franklin PD, Karbassi JA, Li W, Yang W, Ayers DC. Reduction in narcotic use after primary total knee arthroplasty and association with patient pain relief and satisfaction. J Arthroplasty. 2010 Sep; 25(6 Suppl):12-6.
          View in: PubMed
        27. Anderson SA, Li X, Franklin P, Wixted JJ. Ankle fractures in the elderly: initial and long-term outcomes. Foot Ankle Int. 2008 Dec; 29(12):1184-8.
          View in: PubMed
        28. Franklin PD, Li W, Ayers DC. The Chitranjan Ranawat Award: functional outcome after total knee replacement varies with patient attributes. Clin Orthop Relat Res. 2008 Nov; 466(11):2597-604.
          View in: PubMed
        29. Li X, Shah A, Franklin P, Merolli R, Bradley J, Busconi B. Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid (Orthovisc) treatment: a case series and review of the literature. J Orthop Surg Res. 2008; 3:43.
          View in: PubMed
        30. Wixted JJ, Reed M, Eskander MS, Millar B, Anderson RC, Bagchi K, Kaur S, Franklin P, Leclair W. The effect of an orthopedic trauma room on after-hours surgery at a level one trauma center. J Orthop Trauma. 2008 Apr; 22(4):234-6.
          View in: PubMed
        31. Brooks D, Eskander M, Eskander J, Franklin P, Connolly P, Sagi HC, Riew KD. The risk of reintubation following anterior cervical spine surgery. Orthopedics. 2008 Mar; 31(3):198.
          View in: PubMed
        32. Franklin PD, Ploutz-Snyder R, Rosenbaum PF, Carey MP, Smith N, Roizen MF. Worksite e-mail health promotion trial: Early lessons. Eval Program Plann. 2006 Nov; 29(4):405-12.
          View in: PubMed
        33. Franklin PD, McLaughlin J, Boisvert CB, Li W, Ayers DC. Pilot study of methods to document quantity and variation of independent patient exercise and activity after total knee arthroplasty. J Arthroplasty. 2006 Sep; 21(6 Suppl 2):157-63.
          View in: PubMed
        34. Franklin PD, Rosenbaum PF, Carey MP, Roizen MF. Using sequential e-mail messages to promote health behaviors: evidence of feasibility and reach in a worksite sample. J Med Internet Res. 2006; 8(1):e3.
          View in: PubMed
        35. Ayers DC, Franklin PD, Ploutz-Snyder R, Boisvert CB. Total knee replacement outcome and coexisting physical and emotional illness. Clin Orthop Relat Res. 2005 Nov; 440:157-61.
          View in: PubMed
        36. Ayers DC, Franklin PD, Trief PM, Ploutz-Snyder R, Freund D. Psychological attributes of preoperative total joint replacement patients: implications for optimal physical outcome. J Arthroplasty. 2004 Oct; 19(7 Suppl 2):125-30.
          View in: PubMed
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