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    David R Cave MD, PhD

    TitleProfessor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentMedicine
    AddressUniversity of Massachusetts Medical School
    55 Lake Avenue North
    Worcester MA 01655
    Phone508-856-8399
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        UNDER CONSTRUCTION



        Bibliographic 
        selected publications
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        1. Gondal B, Ogunsua AA, McIntosh L, Shaikh Y, Cave D. Perforation of the descending colon in severe acute pancreatitis: a case report and literature review. Pancreas. 2014 Apr; 43(3):488-90.
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        2. Olendzki BC, Silverstein TD, Persuitte GM, Ma Y, Baldwin KR, Cave D. An anti-inflammatory diet as treatment for inflammatory bowel disease: a case series report. Nutr J. 2014; 13(1):5.
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        3. Marya N, Karellas A, Foley A, Roychowdhury A, Cave D. Computerized 3-dimensional localization of a video capsule in the abdominal cavity: validation by digital radiography. Gastrointest Endosc. 2014 Apr; 79(4):669-74.
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        4. Gondal B, Charpentier J, Cave D. Hematoperitoneum after small-bowel spiral enteroscopy. Endoscopy. 2013; 45 Suppl 2:E337.
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        5. Leighton JA, Gralnek IM, Cohen SA, Toth E, Cave DR, Wolf DC, Mullin GE, Ketover SR, Legnani PE, Seidman EG, Crowell MD, Bergwerk AJ, Peled R, Eliakim R. Capsule Endoscopy Is Superior to Small-bowel Follow-through and Equivalent to Ileocolonoscopy in Suspected Crohn's Disease. Clin Gastroenterol Hepatol. 2014 Apr; 12(4):609-15.
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        6. Baptista VN, Cave DR. Review. Gastroenterol Hepatol (N Y). 2013 Aug; 9(8):538-40.
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        7. Choi EH, Mergener K, Semrad C, Fisher L, Cave DR, Dodig M, Burke C, Leighton JA, Kastenberg D, Simpson P, Sul J, Bhattacharya K, Charles R, Gerson L, Weber L, Eisen G, Reidel W, Vargo JJ, Wakim-Fleming J, Lo SK. A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope. Gastrointest Endosc. 2013 Aug; 78(2):325-32.
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        8. Singh A, Baptista V, Stoicov C, Cave DR. Evaluation of small bowel bleeding. Curr Opin Gastroenterol. 2013 Mar; 29(2):119-24.
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        9. Singh A, Marshall C, Chaudhuri B, Okoli C, Foley A, Person SD, Bhattacharya K, Cave DR. Timing of video capsule endoscopy relative to overt obscure GI bleeding: implications from a retrospective study. Gastrointest Endosc. 2013 May; 77(5):761-6.
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        10. Kelly JP, Curhan GC, Cave DR, Anderson TE, Kaufman DW. Factors related to colonization with Oxalobacter formigenes in U.S. adults. J Endourol. 2011 Apr; 25(4):673-9.
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        11. Gerson LB, Tokar J, Chiorean M, Lo S, Decker GA, Cave D, Bouhaidar D, Mishkin D, Dye C, Haluszka O, Leighton JA, Zfass A, Semrad C. Complications associated with double balloon enteroscopy at nine US centers. Clin Gastroenterol Hepatol. 2009 Nov; 7(11):1177-82, 1182.e1-3.
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        12. Lembo AJ, Ganz RA, Sheth S, Cave D, Kelly C, Levin P, Kazlas PT, Baldwin PC, Lindmark WR, McGrath JR, Hamblin MR. Treatment of Helicobacter pylori infection with intra-gastric violet light phototherapy: a pilot clinical trial. Lasers Surg Med. 2009 Jul; 41(5):337-44.
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        13. Cave DR. New capsules are being developed with additional and therapeutic possibilities. Preface. Gastrointest Endosc Clin N Am. 2009 Jul; 19(3):xv-xvi.
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        14. Ibrahim AM, Hackford AW, Lee YM, Cave DR. Hemorrhoids can be a source of obscure gastrointestinal bleeding that requires transfusion: report of five patients. Dis Colon Rectum. 2008 Aug; 51(8):1292-4.
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        15. Cave DR, Fleischer DE, Leighton JA, Faigel DO, Heigh RI, Sharma VK, Gostout CJ, Rajan E, Mergener K, Foley A, Lee M, Bhattacharya K. A multicenter randomized comparison of the Endocapsule and the Pillcam SB. Gastrointest Endosc. 2008 Sep; 68(3):487-94.
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        16. Kaufman DW, Kelly JP, Curhan GC, Anderson TE, Dretler SP, Preminger GM, Cave DR. Oxalobacter formigenes may reduce the risk of calcium oxalate kidney stones. J Am Soc Nephrol. 2008 Jun; 19(6):1197-203.
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        17. Pohl J, Blancas JM, Cave D, Choi KY, Delvaux M, Ell C, Gay G, Jacobs MA, Marcon N, Matsui T, May A, Mulder CJ, Pennazio M, Perez-Cuadrado E, Sugano K, Vilmann P, Yamamoto H, Yano T, Zhong JJ. Consensus report of the 2nd International Conference on double balloon endoscopy. Endoscopy. 2008 Feb; 40(2):156-60.
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        18. Cave DR, Ell C. Introduction: global perspectives on double balloon enteroscopy. Gastrointest Endosc. 2007 Sep; 66(3 Suppl):S1.
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        19. Rondonotti E, Spada C, Cave D, Pennazio M, Riccioni ME, De Vitis I, Schneider D, Sprujevnik T, Villa F, Langelier J, Arrigoni A, Costamagna G, de Franchis R. Video capsule enteroscopy in the diagnosis of celiac disease: a multicenter study. Am J Gastroenterol. 2007 Aug; 102(8):1624-31.
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        20. Fix OK, Simon JT, Farraye FA, Oviedo JA, Pratt DS, Chen WT, Cave DR. Obscure gastrointestinal hemorrhage from mesenteric varices diagnosed by video capsule endoscopy. Dig Dis Sci. 2006 Jul; 51(7):1169-74.
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        21. Cave DR. Technology Insight: current status of video capsule endoscopy. Nat Clin Pract Gastroenterol Hepatol. 2006 Mar; 3(3):158-64.
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        22. de Franchis R, Avgerinos A, Barkin J, Cave D, Filoche B. ICCE consensus for bowel preparation and prokinetics. Endoscopy. 2005 Oct; 37(10):1040-5.
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        23. Cave DR. Obscure gastrointestinal bleeding: the role of the tagged red blood cell scan, enteroscopy, and capsule endoscopy. Clin Gastroenterol Hepatol. 2005 Oct; 3(10):959-63.
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        24. Korman LY, Delvaux M, Gay G, Hagenmuller F, Keuchel M, Friedman S, Weinstein M, Shetzline M, Cave D, de Franchis R. Capsule endoscopy structured terminology (CEST): proposal of a standardized and structured terminology for reporting capsule endoscopy procedures. Endoscopy. 2005 Oct; 37(10):951-9.
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        25. Cave D, Legnani P, de Franchis R, Lewis BS. ICCE consensus for capsule retention. Endoscopy. 2005 Oct; 37(10):1065-7.
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        26. Delvaux M, Friedman S, Keuchel M, Hagenmüller F, Weinstein M, Cave D, de Franchis R, Gay G, Korman LY. Structured terminology for capsule endoscopy: results of retrospective testing and validation in 766 small-bowel investigations. Endoscopy. 2005 Oct; 37(10):945-50.
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        27. Eliakim R, Sharma VK, Yassin K, Adler SN, Jacob H, Cave DR, Sachdev R, Mitty RD, Hartmann D, Schilling D, Riemann JF, Bar-Meir S, Bardan E, Fennerty B, Eisen G, Faigel D, Lewis BS, Fleischer DE. A prospective study of the diagnostic accuracy of PillCam ESO esophageal capsule endoscopy versus conventional upper endoscopy in patients with chronic gastroesophageal reflux diseases. J Clin Gastroenterol. 2005 Aug; 39(7):572-8.
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        28. Cave D. Capsule endoscopy and Crohn's disease. Gastrointest Endosc. 2005 Feb; 61(2):262-3.
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        29. Jameson JJ, Cave DR. Hormonal and antihormonal therapy for epistaxis in hereditary hemorrhagic telangiectasia. Laryngoscope. 2004 Apr; 114(4):705-9.
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        30. Stewart CS, Duncan SH, Cave DR. Oxalobacter formigenes and its role in oxalate metabolism in the human gut. FEMS Microbiol Lett. 2004 Jan 15; 230(1):1-7.
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        31. Sachdev R, Cave DR. When is Crohn's disease Crohn's disease? Inflamm Bowel Dis. 2004 Jan; 10(1):63.
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        32. Cave DR. Reading wireless video capsule endoscopy. Gastrointest Endosc Clin N Am. 2004 Jan; 14(1):17-24.
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        33. Sands BE, Arsenault JE, Rosen MJ, Alsahli M, Bailen L, Banks P, Bensen S, Bousvaros A, Cave D, Cooley JS, Cooper HL, Edwards ST, Farrell RJ, Griffin MJ, Hay DW, John A, Lidofsky S, Olans LB, Peppercorn MA, Rothstein RI, Roy MA, Saletta MJ, Shah SA, Warner AS, Wolf JL, Vecchio J, Winter HS, Zawacki JK. Risk of early surgery for Crohn's disease: implications for early treatment strategies. Am J Gastroenterol. 2003 Dec; 98(12):2712-8.
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        34. Cave DR. Capsule enteroscopy in small bowel transplantation: a passing acquaintance or marriage? Dig Liver Dis. 2003 Oct; 35(10):688-90.
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        35. Grübel P, Choi Y, Schneider D, Knox TA, Cave DR. Severe isolated Crohn's-like disease of the gastroduodenal tract. Dig Dis Sci. 2003 Jul; 48(7):1360-5.
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        36. Cave DR. Chronic gastritis and Helicobacter pylori. Semin Gastrointest Dis. 2001 Jul; 12(3):196-202.
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        37. Hoffman JS, Cave DR. Treatment of Helicobacter pylori. Curr Opin Gastroenterol. 2001 Jan; 17(1):30-4.
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        38. Argyros FC, Ghosh M, Huang L, Masubuchi N, Cave DR, Grübel P. Evaluation of a PCR primer based on the isocitrate dehydrogenase gene for detection of Helicobacter pylori in feces. J Clin Microbiol. 2000 Oct; 38(10):3755-8.
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        39. Peterson WL, Fendrick AM, Cave DR, Peura DA, Garabedian-Ruffalo SM, Laine L. Helicobacter pylori-related disease: guidelines for testing and treatment. Arch Intern Med. 2000 May 8; 160(9):1285-91.
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        40. Cave DR, Zanten SV, Carter E, Halpern EF, Klein S, Prather C, Stolte M, Laine L. A multicentre evaluation of the laser assisted ratio analyser (LARA): a novel device for measurement of 13CO2 in the 13C-urea breath test for the detection of Helicobacter pylori infection. Aliment Pharmacol Ther. 1999 Jun; 13(6):747-52.
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        41. Hoffman JS, Katz LM, Cave DR. Efficacy of a 1-week regimen of ranitidine bismuth citrate in combination with metronidazole and clarithromycin for Helicobacter pylori eradication. Aliment Pharmacol Ther. 1999 Apr; 13(4):503-6.
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        42. Achanta KK, Petros JG, Cave DR, Zinny M. Use of intraoperative enteroscopy to diagnose nonsteroidal anti-inflammatory drug injury to the small intestine. Gastrointest Endosc. 1999 Apr; 49(4 Pt 1):544-6.
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        43. Grübel P, Huang L, Masubuchi N, Stutzenberger FJ, Cave DR. Detection of Helicobacter pylori DNA in houseflies (Musca domestica) on three continents. Lancet. 1998 Sep 5; 352(9130):788-9.
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        44. Grübel P, Cave DR. Factors affecting solubility and penetration of clarithromycin through gastric mucus. Aliment Pharmacol Ther. 1998 Jun; 12(6):569-76.
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        45. Moss SF, Fendrick AM, Cave DR, Modlin IM. Helicobacter pylori--more light, less heat. Am J Gastroenterol. 1998 Mar; 93(3):306-10.
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        46. Cave DR, Goddard PJ. Pathobiology of Helicobacter pylori infection. Yale J Biol Med. 1998 Mar-Apr; 71(2):43-51.
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        47. Cave DR. How is Helicobacter pylori transmitted? Gastroenterology. 1997 Dec; 113(6 Suppl):S9-14.
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        48. D'Agostino JA, Petros JG, Semegran AB, Cave DR, Lopez MJ. Complete intraoperative Sonde enteroscopy in the evaluation of recurrent partial small-bowel obstruction. Gastrointest Endosc. 1997 Dec; 46(6):577-8.
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        49. Grübel P, Hoffman JS, Chong FK, Burstein NA, Mepani C, Cave DR. Vector potential of houseflies (Musca domestica) for Helicobacter pylori. J Clin Microbiol. 1997 Jun; 35(6):1300-3.
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        50. Grübel P, Bhaskar KR, Cave DR, Garik P, Stanley HE, Lamont JT. Interaction of an aluminum-magnesium containing antacid and gastric mucus: possible contribution to the cytoprotective function of antacids. Aliment Pharmacol Ther. 1997 Feb; 11(1):139-45.
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        51. Grübel P, Cave DR. [Flies--reservoirs and vectors of Helicobacter pylori]. Fortschr Med. 1997 Jan 30; 115(3):35-6.
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        52. Cave DR, Cooley JS. Intraoperative enteroscopy. Indications and techniques. Gastrointest Endosc Clin N Am. 1996 Oct; 6(4):793-802.
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        53. Sterling MJ, Cave DR. Memory metal stents for palliation of malignant obstruction of the oesophagus and cardia. Gastrointest Endosc. 1996 Oct; 44(4):513-5.
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        54. Cave DR. Transmission and epidemiology of Helicobacter pylori. Am J Med. 1996 May 20; 100(5A):12S-17S; discussion 17S-18S.
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        55. Mitty RD, Cave DR, Birkett DH. One-stage retrograde approach to Nd:YAG laser palliation of esophageal carcinoma. Endoscopy. 1996 May; 28(4):350-5.
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        56. Lopez MJ, Cooley JS, Petros JG, Sullivan JG, Cave DR. Complete intraoperative small-bowel endoscopy in the evaluation of occult gastrointestinal bleeding using the sonde enteroscope. Arch Surg. 1996 Mar; 131(3):272-7.
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        57. Cave DR, Hoffman JS. Management of Helicobacter pylori infection in ulcer disease. Hosp Pract (1995). 1996 Jan 15; 31(1):63-4, 67-9, 73-5.
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        58. Cave DR. Helicobacter pylori and its interaction with chief and parietal cells. Yale J Biol Med. 1996 Jan-Feb; 69(1):91-8.
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        59. Mitty R, Cave DR. Randomized trial of endoscopic stenting versus surgical bypass in malignant low bile duct obstruction. Gastrointest Endosc. 1995 Sep; 42(3):281-2.
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        60. Hoffman JS, King WW, Fox JG, Janik D, Cave DR. Rabbit and ferret parietal cell inhibition by Helicobacter species. Dig Dis Sci. 1995 Jan; 40(1):147-52.
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        61. Hoffman JS, Cave DR, Birkett D. Intra-operative enteroscopy with a sonde intestinal fiberscope. Gastrointest Endosc. 1994 Mar-Apr; 40(2 Pt 1):229-30.
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        62. Cave DR. Therapeutic approaches to recurrent peptic ulcer disease. Hosp Pract (Off Ed). 1992 Sep 30; 27(9A):33-40, 43, 47-9.
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        63. Vargas M, Lee A, Fox JG, Cave DR. Inhibition of acid secretion from parietal cells by non-human-infecting Helicobacter species: a factor in colonization of gastric mucosa? Infect Immun. 1991 Oct; 59(10):3694-9.
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        64. King WW, Cave DR. Use of esmolol to control autonomic instability of tetanus. Am J Med. 1991 Oct; 91(4):425-8.
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        65. O'Leary DP, Cave DR, Greenfield A, Kuligowska E, Birkett DH. Endoscopic pulsed dye laser lithotripsy of gallbladder calculi in vivo. Gastrointest Endosc. 1991 Mar-Apr; 37(2):143-6.
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        66. Cave TR, Cave DR. Helicobacter pylori stimulates pepsin secretion from isolated rabbit gastric glands. Scand J Gastroenterol Suppl. 1991; 181:9-14.
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        67. Murray FE, Bowers GJ, Birkett DH, Cave DR. Response to Simko. Am J Gastroenterol. 1989 Sep; 84(9):1130-1.
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        68. Cave DR, Vargas M. Effect of a Campylobacter pylori protein on acid secretion by parietal cells. Lancet. 1989 Jul 22; 2(8656):187-9.
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        69. Lerman RH, Cave DR. Medical and surgical management of obesity. Adv Intern Med. 1989; 34:127-63.
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        70. Murray FE, Bowers GJ, Birkett DH, Cave DR. Palliative laser therapy of advanced esophageal carcinoma: an alternative perspective. Am J Gastroenterol. 1988 Aug; 83(8):816-9.
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        71. Murray FE, Guben J, Birkett DH, Cave DR. Dilatation of 'impossible' malignant oesophageal strictures using angiographic techniques. Gut. 1988 Apr; 29(4):555-6.
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        72. Murray FE, Cave DR. Laser surgery of the oesophagus. Lancet. 1987 Dec 26; 2(8574):1532-3.
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        73. Murray FE, Birkett DH, Guben J, Cave DR. Cannulation of difficult malignant esophageal strictures with angiographic catheters. Gastrointest Endosc. 1987 Oct; 33(5):377-8.
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        74. Murray FE, Birkett DH, Cave DR. A simplified method of endoscope insertion following esophageal dilatation of malignant esophageal strictures. Gastrointest Endosc. 1987 Jun; 33(3):268-9.
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        75. Cave DR, Robinson WR, Brotschi EA. Necrotizing fasciitis following percutaneous endoscopic gastrostomy. Gastrointest Endosc. 1986 Aug; 32(4):294-6.
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        76. Koch TR, Cave DR, Ford H, Kirsner JB. Crohn's ileitis and ileocolitis: a study of the anatomical distribution of recurrence. Dig Dis Sci. 1981 Jun; 26(6):528-31.
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