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    Last Name
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    Craig M Lilly MD

    TitleProfessor
    InstitutionUniversity of Massachusetts Medical School
    DepartmentMedicine
    AddressUMass Memorial Medical Center
    281 Lincoln Street
    Worcester MA 01605
    Phone508-856-1919
      Other Positions
      InstitutionUMMS - School of Medicine
      DepartmentAnesthesiology

      InstitutionUMMS - School of Medicine
      DepartmentSurgery

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentClinical Population Health Research

      InstitutionUMMS - Graduate School of Biomedical Sciences
      DepartmentImmunology and Virology

        Bibliographic 
        selected publications
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        1. Lilly CM. Protocol-based care for early septic shock. N Engl J Med. 2014 Jul 24; 371(4):386-7.
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        2. Lilly CM, Liu X, Badawi O, Franey CS, Zuckerman IH. Thrombosis prophylaxis and mortality risk among critically ill adults. Chest. 2014 Jul 1; 146(1):51-7.
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        3. Lilly CM. The ProCESS Trial - A New Era of Sepsis Management. N Engl J Med. 2014 May 1; 370(18):1750-1.
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        4. Lilly CM, McLaughlin JM, Zhao H, Baker SP, Cody S, Irwin RS. A multicenter study of ICU telemedicine reengineering of adult critical care. Chest. 2014 Mar 1; 145(3):500-7.
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        5. Lilly CM, Ellison RT. Quality measures for critically ill patients: where does ventilator-associated condition fit in? Chest. 2013 Nov 1; 144(5):1429-30.
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        6. Ellis KA, Hosseinnezhad A, Ullah A, Vinagre YM, Baker SP, Lilly CM. Prehospital management of evolving critical illness by the primary care provider. Chest. 2013 Oct; 144(4):1216-21.
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        7. Lilly CM, Welch VL, Mayer T, Ranauro P, Meisner J, Luke DR. Evaluation of intravenous voriconazole in patients with compromised renal function. BMC Infect Dis. 2013; 13:14.
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        8. Irwin RS, Flaherty HM, French CT, Cody S, Chandler MW, Connolly A, Lilly CM. Interdisciplinary collaboration: the slogan that must be achieved for models of delivering critical care to be successful. Chest. 2012 Dec; 142(6):1611-9.
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        9. Lilly CM, Fisher KA, Ries M, Pastores SM, Vender J, Pitts JA, Hanson CW. A national ICU telemedicine survey: validation and results. Chest. 2012 Jul; 142(1):40-7.
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        10. Zhao H, Heard SO, Mullen MT, Crawford S, Goldberg RJ, Frendl G, Lilly CM. An evaluation of the diagnostic accuracy of the 1991 American College of Chest Physicians/Society of Critical Care Medicine and the 2001 Society of Critical Care Medicine/European Society of Intensive Care Medicine/American College of Chest Physicians/American Thoracic Society/Surgical Infection Society sepsis definition. Crit Care Med. 2012 Jun; 40(6):1700-6.
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        11. Lilly CM, Zuckerman IH, Badawi O, Riker RR. Benchmark data from more than 240,000 adults that reflect the current practice of critical care in the United States. Chest. 2011 Nov; 140(5):1232-42.
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        12. Kahn JM, Hill NS, Lilly CM, Angus DC, Jacobi J, Rubenfeld GD, Rothschild JM, Sales AE, Scales DC, Mathers JA. The research agenda in ICU telemedicine: a statement from the Critical Care Societies Collaborative. Chest. 2011 Jul; 140(1):230-8.
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        13. Oguma T, Asano K, Tomomatsu K, Kodama M, Fukunaga K, Shiomi T, Ohmori N, Ueda S, Takihara T, Shiraishi Y, Sayama K, Kagawa S, Natori Y, Lilly CM, Satoh K, Makimura K, Ishizaka A. Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cells. J Immunol. 2011 Jul 15; 187(2):999-1005.
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        14. Lilly CM, Cody S, Zhao H, Landry K, Baker SP, McIlwaine J, Chandler MW, Irwin RS. Hospital mortality, length of stay, and preventable complications among critically ill patients before and after tele-ICU reengineering of critical care processes. JAMA. 2011 Jun 1; 305(21):2175-83.
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        15. Daly BJ, Douglas SL, O'Toole E, Gordon NH, Hejal R, Peerless J, Rowbottom J, Garland A, Lilly C, Wiencek C, Hickman R. Effectiveness trial of an intensive communication structure for families of long-stay ICU patients. Chest. 2010 Dec; 138(6):1340-8.
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        16. Sonna LA, Kuhlmeier MM, Khatri P, Chen D, Lilly CM. A microarray analysis of the effects of moderate hypothermia and rewarming on gene expression by human hepatocytes (HepG2). Cell Stress Chaperones. 2010 Sep; 15(5):687-702.
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        17. Forni A, Skehan N, Hartman CA, Yogaratnam D, Njoroge M, Schifferdecker C, Lilly CM. Evaluation of the impact of a tele-ICU pharmacist on the management of sedation in critically ill mechanically ventilated patients. Ann Pharmacother. 2010 Mar; 44(3):432-8.
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        18. Kloek J, Mortaz E, van Ark I, Lilly CM, Nijkamp FP, Folkerts G. Glutathione prevents the early asthmatic reaction and airway hyperresponsiveness in guinea pigs. J Physiol Pharmacol. 2010 Feb; 61(1):67-72.
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        19. Lilly CM, Thomas EJ. Tele-ICU: experience to date. J Intensive Care Med. 2010 Jan-Feb; 25(1):16-22.
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        20. Haley KJ, Sunday ME, Porrata Y, Kelley C, Twomey A, Shahsafaei A, Galper B, Sonna LA, Lilly CM. Ontogeny of the eotaxins in human lung. Am J Physiol Lung Cell Mol Physiol. 2008 Feb; 294(2):L214-24.
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        21. Thomas SY, Banerji A, Medoff BD, Lilly CM, Luster AD. Multiple chemokine receptors, including CCR6 and CXCR3, regulate antigen-induced T cell homing to the human asthmatic airway. J Immunol. 2007 Aug 1; 179(3):1901-12.
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        22. Thompson MD, Capra V, Takasaki J, Maresca G, Rovati GE, Slutsky AS, Lilly C, Zamel N, McIntyre Burnham W, Cole DE, Siminovitch KA. A functional G300S variant of the cysteinyl leukotriene 1 receptor is associated with atopy in a Tristan da Cunha isolate. Pharmacogenet Genomics. 2007 Jul; 17(7):539-49.
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        23. Lilly CM, Daly BJ. The healing power of listening in the ICU. N Engl J Med. 2007 Feb 1; 356(5):513-5.
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        24. Greenwood B, Szumita PM, Levy H, Lilly CM. Error rates among clinical pharmacists in calculating the APACHE II score. Pharmacotherapy. 2007 Feb; 27(2):285-9.
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        25. Sonna LA, Sawka MN, Lilly CM. Exertional heat illness and human gene expression. Prog Brain Res. 2007; 162:321-46.
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        26. Tsai YJ, Choudhry S, Kho J, Beckman K, Tsai HJ, Navarro D, Matallana H, Castro RA, Lilly CM, Nazario S, Rodriguez-Santana JR, Casal J, Torres A, Salas J, Chapela R, Watson HG, Meade K, Avila PC, Rodriguez-Cintron W, LeNoir M, Burchard EG. The PTGDR gene is not associated with asthma in 3 ethnically diverse populations. J Allergy Clin Immunol. 2006 Dec; 118(6):1242-8.
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        27. Soyer OU, Dizdar EA, Keskin O, Lilly C, Kalayci O. Comparison of two methods for exhaled breath condensate collection. Allergy. 2006 Aug; 61(8):1016-8.
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        28. Thomas SY, Lilly CM, Luster AD. Invariant natural killer T cells in bronchial asthma. N Engl J Med. 2006 Jun 15; 354(24):2613-6; author reply 2613-6.
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        29. Tsai HJ, Shaikh N, Kho JY, Battle N, Naqvi M, Navarro D, Matallana H, Lilly CM, Eng CS, Kumar G, Thyne S, Watson HG, Meade K, LeNoir M, Choudhry S, Burchard EG. Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics. Hum Genet. 2006 Jun; 119(5):547-57.
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        30. Sonna LA, Kuhlmeier MM, Carter HC, Hasday JD, Lilly CM, Fairchild KD. Effect of moderate hypothermia on gene expression by THP-1 cells: a DNA microarray study. Physiol Genomics. 2006 Jun 16; 26(1):91-8.
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        31. Kalayci O, Birben E, Sackesen C, Keskin O, Tahan F, Wechsler ME, Civelek E, Soyer OU, Adalioglu G, Tuncer A, Israel E, Lilly C. ALOX5 promoter genotype, asthma severity and LTC production by eosinophils. Allergy. 2006 Jan; 61(1):97-103.
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        32. Medoff BD, Thomas SY, Banerji A, Wain JC, Zhang H, Lilly CM, Ginns LC, Luster AD. Pathogenic T-cell recruitment into the airway in human disease. Ann N Y Acad Sci. 2005 Dec; 1062:220-41.
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        33. Lilly CM, Landrigan CP. A shift for the better. Chest. 2005 Dec; 128(6):3787-8.
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        34. Tsai HJ, Kho JY, Shaikh N, Choudhry S, Naqvi M, Navarro D, Matallana H, Castro R, Lilly CM, Watson HG, Meade K, Lenoir M, Thyne S, Ziv E, Burchard EG. Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet. 2006 Jan; 118(5):626-39.
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        35. Islam SA, Thomas SY, Hess C, Medoff BD, Means TK, Brander C, Lilly CM, Tager AM, Luster AD. The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans. Blood. 2006 Jan 15; 107(2):444-53.
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        36. Lilly CM, Palmer LJ. The role of prostaglandin D receptor gene in asthma pathogenesis. Am J Respir Cell Mol Biol. 2005 Sep; 33(3):224-6.
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        37. Waxman AB, Ward N, Thompson T, Lilly CM, Lisbon A, Hill N, Nasraway SA, Heard S, Corwin H, Levy M. Roundtable debate: Controversies in the management of the septic patient--desperately seeking consensus. Crit Care. 2005 Feb; 9(1):E1.
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        38. Rothschild JM, Landrigan CP, Cronin JW, Kaushal R, Lockley SW, Burdick E, Stone PH, Lilly CM, Katz JT, Czeisler CA, Bates DW. The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care. Crit Care Med. 2005 Aug; 33(8):1694-700.
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        39. Choudhry S, Avila PC, Nazario S, Ung N, Kho J, Rodriguez-Santana JR, Casal J, Tsai HJ, Torres A, Ziv E, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Castro RA, Selman M, Weiss ST, Ford JG, Drazen JM, Rodriguez-Cintron W, Chapela R, Silverman EK, Burchard EG. CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma. Am J Respir Crit Care Med. 2005 Jul 15; 172(2):173-82.
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        40. Adams CD, Szumita PM, Baroletti SA, Lilly CM. Azacitidine-induced interstitial and alveolar fibrosis in a patient with myelodysplastic syndrome. Pharmacotherapy. 2005 May; 25(5):765-8.
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        41. Lilly CM. Diversity of asthma: evolving concepts of pathophysiology and lessons from genetics. J Allergy Clin Immunol. 2005 Apr; 115(4 Suppl):S526-31.
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        42. Lilly CM, Tateno H, Oguma T, Israel E, Sonna LA. Effects of allergen challenge on airway epithelial cell gene expression. Am J Respir Crit Care Med. 2005 Mar 15; 171(6):579-86.
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        43. Zuberi RI, Hsu DK, Kalayci O, Chen HY, Sheldon HK, Yu L, Apgar JR, Kawakami T, Lilly CM, Liu FT. Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol. 2004 Dec; 165(6):2045-53.
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        44. Choudhry S, Ung N, Avila PC, Ziv E, Nazario S, Casal J, Torres A, Gorman JD, Salari K, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Castro RA, Salazar M, Gomez I, Fagan JK, Salas J, Clark S, Lilly C, Matallana H, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Drazen JM, Rodriguez-Cintron W, Silverman EK, Burchard EG. Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med. 2005 Mar 15; 171(6):563-70.
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        45. Kalayci O, Birben E, Tinari N, Oguma T, Iacobelli S, Lilly CM. Role of 90K protein in asthma and TH2-type cytokine expression. Ann Allergy Asthma Immunol. 2004 Nov; 93(5):485-92.
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        46. Landrigan CP, Rothschild JM, Cronin JW, Kaushal R, Burdick E, Katz JT, Lilly CM, Stone PH, Lockley SW, Bates DW, Czeisler CA. Effect of reducing interns' work hours on serious medical errors in intensive care units. N Engl J Med. 2004 Oct 28; 351(18):1838-48.
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        47. Lockley SW, Cronin JW, Evans EE, Cade BE, Lee CJ, Landrigan CP, Rothschild JM, Katz JT, Lilly CM, Stone PH, Aeschbach D, Czeisler CA. Effect of reducing interns' weekly work hours on sleep and attentional failures. N Engl J Med. 2004 Oct 28; 351(18):1829-37.
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        48. Oguma T, Palmer LJ, Birben E, Sonna LA, Asano K, Lilly CM. Role of prostanoid DP receptor variants in susceptibility to asthma. N Engl J Med. 2004 Oct 21; 351(17):1752-63.
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        49. Tateno H, Nakamura H, Minematsu N, Nakajima T, Takahashi S, Nakamura M, Fukunaga K, Asano K, Lilly CM, Yamaguchi K. Plasma eotaxin level and severity of asthma treated with corticosteroid. Respir Med. 2004 Aug; 98(8):782-90.
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        50. Tschumperlin DJ, Dai G, Maly IV, Kikuchi T, Laiho LH, McVittie AK, Haley KJ, Lilly CM, So PT, Lauffenburger DA, Kamm RD, Drazen JM. Mechanotransduction through growth-factor shedding into the extracellular space. Nature. 2004 May 6; 429(6987):83-6.
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        51. Sonna LA, Wenger CB, Flinn S, Sheldon HK, Sawka MN, Lilly CM. Exertional heat injury and gene expression changes: a DNA microarray analysis study. J Appl Physiol (1985). 2004 May; 96(5):1943-53.
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        52. Kalayci O, Sonna LA, Woodruff PG, Camargo CA, Luster AD, Lilly CM. Monocyte chemotactic protein-4 (MCP-4; CCL-13): a biomarker of asthma. J Asthma. 2004 Feb; 41(1):27-33.
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        53. Fischer MA, Lilly CM, Churchill WW, Baden LR, Avorn J. An algorithmic computerised order entry approach to assist in the prescribing of new therapeutic agents: case study of activated protein C at an academic medical centre. Drug Saf. 2004; 27(15):1253-61.
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        54. Burchard EG, Avila PC, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Toscano M, Sylvia JS, Alioto M, Salazar M, Gomez I, Fagan JK, Salas J, Lilly C, Matallana H, Ziv E, Castro R, Selman M, Chapela R, Sheppard D, Weiss ST, Ford JG, Boushey HA, Rodriguez-Cintron W, Drazen JM, Silverman EK. Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med. 2004 Feb 1; 169(3):386-92.
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        55. Lind DL, Choudhry S, Ung N, Ziv E, Avila PC, Salari K, Ha C, Lovins EG, Coyle NE, Nazario S, Casal J, Torres A, Rodriguez-Santana JR, Matallana H, Lilly CM, Salas J, Selman M, Boushey HA, Weiss ST, Chapela R, Ford JG, Rodriguez-Cintron W, Silverman EK, Sheppard D, Kwok PY, González Burchard E. ADAM33 is not associated with asthma in Puerto Rican or Mexican populations. Am J Respir Crit Care Med. 2003 Dec 1; 168(11):1312-6.
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        56. Kalayci O, Birben E, Wu L, Oguma T, Storm Van's Gravesande K, Subramaniam V, Sheldon HK, Silverman ES, Lilly CM. Monocyte chemoattractant protein-4 core promoter genetic variants: influence on YY-1 affinity and plasma levels. Am J Respir Cell Mol Biol. 2003 Dec; 29(6):750-6.
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        57. Lilly CM, Sonna LA, Haley KJ, Massaro AF. Intensive communication: four-year follow-up from a clinical practice study. Crit Care Med. 2003 May; 31(5 Suppl):S394-9.
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        58. Sonna LA, Cullivan ML, Sheldon HK, Pratt RE, Lilly CM. Effect of hypoxia on gene expression by human hepatocytes (HepG2). Physiol Genomics. 2003 Feb 6; 12(3):195-207.
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        59. Kalayci O, Wechsler M, Galper B, Hong C, Israel E, Drazen JM, Lilly CM. LTC4 production by eosinophils in asthmatic subjects with alternative forms of ALOX-5 core promoter. Adv Exp Med Biol. 2003; 525:11-4.
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        60. Shah PB, Lilly CM. Interventional therapy for coronary artery disease. Am J Respir Crit Care Med. 2002 Sep 15; 166(6):791-6.
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        61. Shikanai T, Silverman ES, Morse BW, Lilly CM, Inoue H, Drazen JM. Sequence variants in the FcepsilonRI alpha chain gene. J Appl Physiol (1985). 2002 Jul; 93(1):37-41.
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        62. Sonna LA, Gaffin SL, Pratt RE, Cullivan ML, Angel KC, Lilly CM. Effect of acute heat shock on gene expression by human peripheral blood mononuclear cells. J Appl Physiol (1985). 2002 May; 92(5):2208-20.
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        63. Sonna LA, Fujita J, Gaffin SL, Lilly CM. Invited review: Effects of heat and cold stress on mammalian gene expression. J Appl Physiol (1985). 2002 Apr; 92(4):1725-42.
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        64. Oguma T, Asano K, Shiomi T, Fukunaga K, Suzuki Y, Nakamura M, Matsubara H, Sheldon HK, Haley KJ, Lilly CM, Drazen JM, Yamaguchi K. Cyclooxygenase-2 expression during allergic inflammation in guinea-pig lungs. Am J Respir Crit Care Med. 2002 Feb 1; 165(3):382-6.
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        65. Lilly CM, Churg A, Lazarovich M, Pauwels R, Hendeles L, Rosenwasser LJ, Ledford D, Wechsler ME. Asthma therapies and Churg-Strauss syndrome. J Allergy Clin Immunol. 2002 Jan; 109(1):S1-19.
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        66. Morse B, Sypek JP, Donaldson DD, Haley KJ, Lilly CM. Effects of IL-13 on airway responses in the guinea pig. Am J Physiol Lung Cell Mol Physiol. 2002 Jan; 282(1):L44-9.
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        67. Nakamura H, Luster AD, Nakamura T, In KH, Sonna LA, Deykin A, Israel E, Drazen JM, Lilly CM. Variant eotaxin: its effects on the asthma phenotype. J Allergy Clin Immunol. 2001 Dec; 108(6):946-53.
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        68. Lilly CM, Daugherty BL. A novel LPS-inducible CCR3 activator: why so many CCR3 ligands? Am J Respir Cell Mol Biol. 2001 Dec; 25(6):673-5.
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        69. Nakamura H, Luster AD, Tateno H, Jedrzkiewicz S, Tamura G, Haley KJ, Garcia-Zepeda EA, Yamaguchi K, Lilly CM. IL-4 differentially regulates eotaxin and MCP-4 in lung epithelium and circulating mononuclear cells. Am J Physiol Lung Cell Mol Physiol. 2001 Nov; 281(5):L1288-302.
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        70. Sonna LA, Sharp MA, Knapik JJ, Cullivan M, Angel KC, Patton JF, Lilly CM. Angiotensin-converting enzyme genotype and physical performance during US Army basic training. J Appl Physiol (1985). 2001 Sep; 91(3):1355-63.
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        71. Sonna LA, Angel KC, Sharp MA, Knapik JJ, Patton JF, Lilly CM. The prevalence of exercise-induced bronchospasm among US Army recruits and its effects on physical performance. Chest. 2001 Jun; 119(6):1676-84.
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        72. Lilly CM, Nakamura H, Belostotsky OI, Haley KJ, Garcia-Zepeda EA, Luster AD, Israel E. Eotaxin expression after segmental allergen challenge in subjects with atopic asthma. Am J Respir Crit Care Med. 2001 Jun; 163(7):1669-75.
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        73. Haley KJ, Sunday ME, Osathanondh R, Du J, Vathanaprida C, Karpitsky VV, Krause JE, Lilly CM. Developmental expression of neurokinin A and functional neurokinin-2 receptors in lung. Am J Physiol Lung Cell Mol Physiol. 2001 Jun; 280(6):L1348-58.
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        74. Tateno H, Nakamura H, Minematsu N, Amakawa K, Terashima T, Fujishima S, Luster AD, Lilly CM, Yamaguchi K. Eotaxin and monocyte chemoattractant protein-1 in chronic eosinophilic pneumonia. Eur Respir J. 2001 May; 17(5):962-8.
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        75. Jedrzkiewicz S, Nakamura H, Silverman ES, Luster AD, Mansharamani N, In KH, Tamura G, Lilly CM. IL-1beta induces eotaxin gene transcription in A549 airway epithelial cells through NF-kappaB. Am J Physiol Lung Cell Mol Physiol. 2000 Dec; 279(6):L1058-65.
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        76. Deykin A, Belostotsky O, Hong C, Massaro AF, Lilly CM, Israel E. Exhaled nitric oxide following leukotriene E(4) and methacholine inhalation in patients with asthma. Am J Respir Crit Care Med. 2000 Nov; 162(5):1685-9.
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        77. Haley KJ, Lilly CM, Yang JH, Feng Y, Kennedy SP, Turi TG, Thompson JF, Sukhova GH, Libby P, Lee RT. Overexpression of eotaxin and the CCR3 receptor in human atherosclerosis: using genomic technology to identify a potential novel pathway of vascular inflammation. Circulation. 2000 Oct 31; 102(18):2185-9.
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        78. Lilly CM, De Meo DL, Sonna LA, Haley KJ, Massaro AF, Wallace RF, Cody S. An intensive communication intervention for the critically ill. Am J Med. 2000 Oct 15; 109(6):469-75.
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        79. Harel Z, Lilly C, Riggs S, Vaz R, Drazen J. Urinary leukotriene (LT) E(4) in adolescents with dysmenorrhea: a pilot study. J Adolesc Health. 2000 Sep; 27(3):151-4.
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        80. Humbles AA, Lu B, Nilsson CA, Lilly C, Israel E, Fujiwara Y, Gerard NP, Gerard C. A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Nature. 2000 Aug 31; 406(6799):998-1001.
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        81. Lamkhioued B, Garcia-Zepeda EA, Abi-Younes S, Nakamura H, Jedrzkiewicz S, Wagner L, Renzi PM, Allakhverdi Z, Lilly C, Hamid Q, Luster AD. Monocyte chemoattractant protein (MCP)-4 expression in the airways of patients with asthma. Induction in epithelial cells and mononuclear cells by proinflammatory cytokines. Am J Respir Crit Care Med. 2000 Aug; 162(2 Pt 1):723-32.
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        82. Grasemann H, Yandava CN, Storm van's Gravesande K, Deykin A, Pillari A, Ma J, Sonna LA, Lilly C, Stampfer MJ, Israel E, Silverman EK, Drazen JM. A neuronal NO synthase (NOS1) gene polymorphism is associated with asthma. Biochem Biophys Res Commun. 2000 Jun 7; 272(2):391-4.
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        83. Nakamura H, Weiss ST, Israel E, Luster AD, Drazen JM, Lilly CM. Eotaxin and impaired lung function in asthma. Am J Respir Crit Care Med. 1999 Dec; 160(6):1952-6.
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        84. Lilly CM, Woodruff PG, Camargo CA, Nakamura H, Drazen JM, Nadel ES, Hanrahan JP. Elevated plasma eotaxin levels in patients with acute asthma. J Allergy Clin Immunol. 1999 Oct; 104(4 Pt 1):786-90.
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        85. Burchard EG, Silverman EK, Rosenwasser LJ, Borish L, Yandava C, Pillari A, Weiss ST, Hasday J, Lilly CM, Ford JG, Drazen JM. Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma. Am J Respir Crit Care Med. 1999 Sep; 160(3):919-22.
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        86. Mehta S, Boudreau J, Lilly CM, Drazen JM. Endogenous pulmonary nitric oxide in the regulation of airway microvascular leak. Am J Physiol. 1998 Nov; 275(5 Pt 1):L961-8.
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        87. Nakamura H, Haley KJ, Nakamura T, Luster AD, Lilly CM. Differential regulation of eotaxin expression by TNF-alpha and PMA in human monocytic U-937 cells. Am J Physiol. 1998 Sep; 275(3 Pt 1):L601-10.
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        88. Takebayashi T, Abraham J, Murthy GG, Lilly C, Rodger I, Shore SA. Role of tachykinins in airway responses to ozone in rats. J Appl Physiol (1985). 1998 Aug; 85(2):442-50.
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        89. Cook EB, Stahl JL, Lilly CM, Haley KJ, Sanchez H, Luster AD, Graziano FM, Rothenberg ME. Epithelial cells are a major cellular source of the chemokine eotaxin in the guinea pig lung. Allergy Asthma Proc. 1998 Jan-Feb; 19(1):15-22.
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        90. Mehta S, Drazen JM, Lilly CM. Endogenous nitric oxide and allergic bronchial hyperresponsiveness in guinea pigs. Am J Physiol. 1997 Sep; 273(3 Pt 1):L656-62.
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        91. Lilly CM, Nakamura H, Kesselman H, Nagler-Anderson C, Asano K, Garcia-Zepeda EA, Rothenberg ME, Drazen JM, Luster AD. Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. J Clin Invest. 1997 Apr 1; 99(7):1767-73.
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        92. Asano K, Nakamura H, Lilly CM, Klagsbrun M, Drazen JM. Interferon gamma induces prostaglandin G/H synthase-2 through an autocrine loop via the epidermal growth factor receptor in human bronchial epithelial cells. J Clin Invest. 1997 Mar 1; 99(5):1057-63.
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        93. Sobh JF, Lilly CM, Drazen JM, Jackson AC. Respiratory transfer impedance between 8 and 384 Hz in guinea pigs before and after bronchial challenge. J Appl Physiol (1985). 1997 Jan; 82(1):172-81.
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        94. Mehta S, Lilly CM, Rollenhagen JE, Haley KJ, Asano K, Drazen JM. Acute and chronic effects of allergic airway inflammation on pulmonary nitric oxide production. Am J Physiol. 1997 Jan; 272(1 Pt 1):L124-31.
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        95. Fraser JL, Lilly C, Israel E, Hulme P, Hanff PA. Diagnostic yield of bronchoalveolar lavage and bronchoscopic lung biopsy for detection of Pneumocystis carinii. Mayo Clin Proc. 1996 Nov; 71(11):1025-9.
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        96. Roach JM, Muza SR, Rock PB, Lyons TP, Lilly CM, Drazen JM, Cymerman A. Urinary leukotriene E4 levels increase upon exposure to hypobaric hypoxia. Chest. 1996 Oct; 110(4):946-51.
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        97. Asano K, Lilly CM, Drazen JM. Prostaglandin G/H synthase-2 is the constitutive and dominant isoform in cultured human lung epithelial cells. Am J Physiol. 1996 Jul; 271(1 Pt 1):L126-31.
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        98. Mansour M, Karmilowicz M, Hawrylik SJ, Nalcerio B, Angilly J, Conklyn MJ, Lilly CM, Drazen JM, Lee SE, Auperin DD, De Wet JR, Cohan VL, Showell HJ, Danley DE. Production and characterization of guinea pig IL-5 in baculovirus-infected insect cells. Am J Physiol. 1996 Jun; 270(6 Pt 1):L1002-7.
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        99. Massaro AF, Mehta S, Lilly CM, Kobzik L, Reilly JJ, Drazen JM. Elevated nitric oxide concentrations in isolated lower airway gas of asthmatic subjects. Am J Respir Crit Care Med. 1996 May; 153(5):1510-4.
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        100. Lilly CM, Chapman RW, Sehring SJ, Mauser PJ, Egan RW, Drazen JM. Effects of interleukin 5-induced pulmonary eosinophilia on airway reactivity in the guinea pig. Am J Physiol. 1996 Mar; 270(3 Pt 1):L368-75.
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        101. Asano K, Lilly CM, O'Donnell WJ, Israel E, Fischer A, Ransil BJ, Drazen JM. Diurnal variation of urinary leukotriene E4 and histamine excretion rates in normal subjects and patients with mild-to-moderate asthma. J Allergy Clin Immunol. 1995 Nov; 96(5 Pt 1):643-51.
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        102. Ingenito EP, Mark L, Lilly C, Davison B. Autonomic regulation of tissue resistance in the guinea pig lung. J Appl Physiol (1985). 1995 Apr; 78(4):1382-7.
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        103. Lilly CM, Hall AE, Rodger IW, Kobzik L, Haley KJ, Drazen JM. Substance P-induced histamine release in tracheally perfused guinea pig lungs. J Appl Physiol (1985). 1995 Apr; 78(4):1234-41.
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        104. Rothenberg ME, Luster AD, Lilly CM, Drazen JM, Leder P. Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung. J Exp Med. 1995 Mar 1; 181(3):1211-6.
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        105. Lilly CM, Bai TR, Shore SA, Hall AE, Drazen JM. Neuropeptide content of lungs from asthmatic and nonasthmatic patients. Am J Respir Crit Care Med. 1995 Feb; 151(2 Pt 1):548-53.
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        106. Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Rubin P, Cohn J, White MV, Igarashi Y, Kaliner MA, Drazen JM, et al. Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 1):1046-56.
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        107. Asano K, Chee CB, Gaston B, Lilly CM, Gerard C, Drazen JM, Stamler JS. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells. Proc Natl Acad Sci U S A. 1994 Oct 11; 91(21):10089-93.
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        108. Lilly CM, Kobzik L, Hall AE, Drazen JM. Effects of chronic airway inflammation on the activity and enzymatic inactivation of neuropeptides in guinea pig lungs. J Clin Invest. 1994 Jun; 93(6):2667-74.
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        109. Lilly CM, Besson G, Israel E, Rodger IW, Drazen JM. Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs. Am J Respir Crit Care Med. 1994 May; 149(5):1175-9.
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        110. Drazen JM, Lilly CM, Sperling R, Rubin P, Israel E. Role of cysteinyl leukotrienes in spontaneous asthmatic responses. Adv Prostaglandin Thromboxane Leukot Res. 1994; 22:251-62.
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        111. Israel E, Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Shapiro J, Cohn J, Rubin P, Drazen JM. The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis. 1993 Dec; 148(6 Pt 1):1447-51.
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        112. Lilly CM, Stamler JS, Gaston B, Meckel C, Loscalzo J, Drazen JM. Modulation of vasoactive intestinal peptide pulmonary relaxation by NO in tracheally superfused guinea pig lungs. Am J Physiol. 1993 Oct; 265(4 Pt 1):L410-5.
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        113. Lilly CM, Drazen JM, Shore SA. Peptidase modulation of airway effects of neuropeptides. Proc Soc Exp Biol Med. 1993 Sep; 203(4):388-404.
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        114. Lilly CM, Martins MA, Drazen JM. Peptidase modulation of vasoactive intestinal peptide pulmonary relaxation in tracheal superfused guinea pig lungs. J Clin Invest. 1993 Jan; 91(1):235-43.
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        115. Harada H, Ishizaka A, Yonemaru M, Mallick AA, Hatherill JR, Zheng H, Lilly CM, O'Hanley PT, Raffin TA. The effects of aminophylline and pentoxifylline on multiple organ damage after Escherichia coli sepsis. Am Rev Respir Dis. 1989 Oct; 140(4):974-80.
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        116. Lilly CM, Sandhu JS, Ishizaka A, Harada H, Yonemaru M, Larrick JW, Shi TX, O'Hanley PT, Raffin TA. Pentoxifylline prevents tumor necrosis factor-induced lung injury. Am Rev Respir Dis. 1989 Jun; 139(6):1361-8.
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        117. Kliman A, Reid NR, Lilly C, Morrison J. Hepatitis-associated antigen (Australia antigen) in Massachusetts blood donors. N Engl J Med. 1971 Sep 30; 285(14):783-5.
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