Stuart M Levitz MD
Title Professor
Institution University of Massachusetts Medical School
Department Medicine
Division Infectious Diseases And Immunology
Address University of Massachusetts Medical School
364 Plantation Street, LRB
Worcester MA 01605
Telephone 508-856-1525
Other Positions
Institution UMMS - School of Medicine
Department Microbiology & Physiological Systems

Institution UMMS - Graduate School of Biomedical Sciences
Department Immunology & Virology

Institution UMMS - Graduate School of Biomedical Sciences
Department Interdisciplinary Graduate Program

Institution UMMS - Graduate School of Biomedical Sciences
Department MD/PhD Program

Institution UMMS - Graduate School of Biomedical Sciences
Department Molecular Genetics & Microbiology
Publications
1. Jarvis JN, Casazza JP, Stone HH, Meintjes G, Lawn SD, Levitz SM, Harrison TS, Koup RA. The Phenotype of the Cryptococcus-Specific CD4+ Memory T-Cell Response Is Associated With Disease Severity and Outcome in HIV-Associated Cryptococcal Meningitis. J Infect Dis. 2013 Jun; 207(12):1817-28.
  View in: PubMed
 
2. Bueter CL, Specht CA, Levitz SM. Innate sensing of chitin and chitosan. PLoS Pathog. 2013 Jan; 9(1):e1003080.
  View in: PubMed
 
3. Brown GD, Denning DW, Gow NA, Levitz SM, Netea MG, White TC. Hidden killers: human fungal infections. Sci Transl Med. 2012 Dec 19; 4(165):165rv13.
  View in: PubMed
 
4. Cariello PF, Wickes BL, Sutton DA, Castlebury LA, Levitz SM, Finberg RW, Thompson EH, Daly JS. Phomopsis bougainvilleicola Prepatellar Bursitis in a Renal Transplant Recipient. J Clin Microbiol. 2013 Feb; 51(2):692-5.
  View in: PubMed
 
5. Hurtgen BJ, Hung CY, Ostroff GR, Levitz SM, Cole GT. Construction and Evaluation of a Novel Recombinant T Cell Epitope-Based Vaccine against Coccidioidomycosis. Infect Immun. 2012 Nov; 80(11):3960-74.
  View in: PubMed
 
6. Huang H, Ostroff GR, Lee CK, Agarwal S, Ram S, Rice PA, Specht CA, Levitz SM. Relative Contributions of Dectin-1 and Complement to Immune Responses to Particulate ß-Glucans. J Immunol. 2012 May 30.
  View in: PubMed
 
7. Brown GD, Denning DW, Levitz SM. Tackling human fungal infections. Science. 2012 May 11; 336(6082):647.
  View in: PubMed
 
8. Levitz SM, Golenbock DT. Beyond Empiricism: Informing Vaccine Development through Innate Immunity Research. Cell. 2012 Mar 16; 148(6):1284-92.
  View in: PubMed
 
9. Cohen NR, Tatituri RV, Rivera A, Watts GF, Kim EY, Chiba A, Fuchs BB, Mylonakis E, Besra GS, Levitz SM, Brigl M, Brenner MB. Innate Recognition of Cell Wall ß-Glucans Drives Invariant Natural Killer T Cell Responses against Fungi. Cell Host Microbe. 2011 Nov 17; 10(5):437-50.
  View in: PubMed
 
10. Kwon-Chung KJ, Perfect JR, Levitz SM. A Chronological History of the International Conference on Cryptococcus and Cryptococcosis (ICCC), an Invaluable Forum for Growth of the Cryptococcal Research Field and Clinical Practice. Mycopathologia. 2012 Jun; 173(5-6):287-93.
  View in: PubMed
 
11. Wang JP, Lee CK, Akalin A, Finberg RW, Levitz SM. Contributions of the MyD88-dependent receptors IL-18R, IL-1R, and TLR9 to host defenses following pulmonary challenge with Cryptococcus neoformans. PLoS One. 2011; 6(10):e26232.
  View in: PubMed
 
12. Mansour MK, Vyas JM, Levitz SM. Dynamic Virulence: Real-Time Assessment of Intracellular Pathogenesis Links Cryptococcus neoformans Phenotype with Clinical Outcome. MBio. 2011; 2(5).
  View in: PubMed
 
13. Agarwal S, Specht CA, Haibin H, Ostroff GR, Ram S, Rice PA, Levitz SM. Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans. MBio. 2011; 2(5).
  View in: PubMed
 
14. Bueter CL, Lee CK, Rathinam VA, Healy GJ, Taron CH, Specht CA, Levitz SM. Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis. J Biol Chem. 2011 Oct 14; 286(41):35447-55.
  View in: PubMed
 
15. Ramirez-Ortiz ZG, Lee CK, Wang JP, Boon L, Specht CA, Levitz SM. A Nonredundant Role for Plasmacytoid Dendritic Cells in Host Defense against the Human Fungal Pathogen Aspergillus fumigatus. Cell Host Microbe. 2011 May 19; 9(5):415-24.
  View in: PubMed
 
16. Jesus MD, Nicola AM, Chow SK, Lee IR, Nong S, Specht CA, Levitz SM, Casadevall A. Glucuronoxylomannan, galactoxylomannan, and mannoprotein occupy spatially separate and discrete regions in the capsule of Cryptococcus neoformans. Virulence. 2011 Jan 10; 1(6):500-8.
  View in: PubMed
 
17. Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM. Robust Stimulation of Humoral and Cellular Immune Responses following Vaccination with Antigen-Loaded beta-Glucan Particles. MBio. 2010; 1(3).
  View in: PubMed
 
18. Levitz SM. Innate recognition of fungal cell walls. PLoS Pathog. 2010 Apr; 6(4):e1000758.
  View in: PubMed
 
19. Levitz SM. Th17 cells bounce off the fungal wall. Cell Host Microbe. 2009 Apr 23; 5(4):311-3.
  View in: PubMed
 
20. Huang H, Ostroff GR, Lee CK, Wang JP, Specht CA, Levitz SM. Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists. Infect Immun. 2009 May; 77(5):1774-81.
  View in: PubMed
 
21. Levitz SM, Shoham S, Cleary JD. Toll-like receptor 4 polymorphisms and aspergillosis. N Engl J Med. 2009 Feb 5; 360(6):634; author reply 635-6.
  View in: PubMed
 
22. Wozniak KL, Levitz SM. Isolation and purification of antigenic components of Cryptococcus. Methods Mol Biol. 2009; 470:71-83.
  View in: PubMed
 
23. Wozniak KL, Levitz SM. Cryptococcus neoformans enters the endolysosomal pathway of dendritic cells and is killed by lysosomal components. Infect Immun. 2008 Oct; 76(10):4764-71.
  View in: PubMed
 
24. Dan JM, Wang JP, Lee CK, Levitz SM. Cooperative stimulation of dendritic cells by Cryptococcus neoformans mannoproteins and CpG oligodeoxynucleotides. PLoS One. 2008; 3(4):e2046.
  View in: PubMed
 
25. Dan JM, Kelly RM, Lee CK, Levitz SM. Role of the mannose receptor in a murine model of Cryptococcus neoformans infection. Infect Immun. 2008 Jun; 76(6):2362-7.
  View in: PubMed
 
26. Ramirez-Ortiz ZG, Specht CA, Wang JP, Lee CK, Bartholomeu DC, Gazzinelli RT, Levitz SM. Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA. Infect Immun. 2008 May; 76(5):2123-9.
  View in: PubMed
 
27. Lam JS, Huang H, Levitz SM. Effect of differential N-linked and O-linked mannosylation on recognition of fungal antigens by dendritic cells. PLoS One. 2007; 2(10):e1009.
  View in: PubMed
 
28. Specht CA, Nong S, Dan JM, Lee CK, Levitz SM. Contribution of glycosylation to T cell responses stimulated by recombinant Cryptococcus neoformans mannoprotein. J Infect Dis. 2007 Sep 1; 196(5):796-800.
  View in: PubMed
 
29. Luong M, Lam JS, Chen J, Levitz SM. Effects of fungal N- and O-linked mannosylation on the immunogenicity of model vaccines. Vaccine. 2007 May 30; 25(22):4340-4.
  View in: PubMed
 
30. Yauch LE, Lam JS, Levitz SM. Direct inhibition of T-cell responses by the Cryptococcus capsular polysaccharide glucuronoxylomannan. PLoS Pathog. 2006 Nov; 2(11):e120.
  View in: PubMed
 
31. Dan JM, Levitz SM. Prospects for development of vaccines against fungal diseases. Drug Resist Updat. 2006 Jun; 9(3):105-10.
  View in: PubMed
 
32. Wozniak KL, Vyas JM, Levitz SM. In vivo role of dendritic cells in a murine model of pulmonary cryptococcosis. Infect Immun. 2006 Jul; 74(7):3817-24.
  View in: PubMed
 
33. Levitz SM, Boekhout T. Cryptococcus: the once-sleeping giant is fully awake. FEMS Yeast Res. 2006 Jun; 6(4):461-2.
  View in: PubMed
 
34. Levitz SM, Specht CA. The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins. FEMS Yeast Res. 2006 Jun; 6(4):513-24.
  View in: PubMed
 
35. Mansour MK, Latz E, Levitz SM. Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells. J Immunol. 2006 Mar 1; 176(5):3053-61.
  View in: PubMed
 
36. Yauch LE, Mansour MK, Levitz SM. Receptor-mediated clearance of Cryptococcus neoformans capsular polysaccharide in vivo. Infect Immun. 2005 Dec; 73(12):8429-32.
  View in: PubMed
 
37. Lam JS, Mansour MK, Specht CA, Levitz SM. A model vaccine exploiting fungal mannosylation to increase antigen immunogenicity. J Immunol. 2005 Dec 1; 175(11):7496-503.
  View in: PubMed
 
38. Banks IR, Specht CA, Donlin MJ, Gerik KJ, Levitz SM, Lodge JK. A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans. Eukaryot Cell. 2005 Nov; 4(11):1902-12.
  View in: PubMed
 
39. Shoham S, Levitz SM. The immune response to fungal infections. Br J Haematol. 2005 Jun; 129(5):569-82.
  View in: PubMed
 
40. Kelly RM, Chen J, Yauch LE, Levitz SM. Opsonic requirements for dendritic cell-mediated responses to Cryptococcus neoformans. Infect Immun. 2005 Jan; 73(1):592-8.
  View in: PubMed
 
41. Herrero AB, Magnelli P, Mansour MK, Levitz SM, Bussey H, Abeijon C. KRE5 gene null mutant strains of Candida albicans are avirulent and have altered cell wall composition and hypha formation properties. Eukaryot Cell. 2004 Dec; 3(6):1423-32.
  View in: PubMed
 
42. Levitz SM. Interactions of Toll-like receptors with fungi. Microbes Infect. 2004 Dec; 6(15):1351-5.
  View in: PubMed
 
43. Yauch LE, Mansour MK, Shoham S, Rottman JB, Levitz SM. Involvement of CD14, toll-like receptors 2 and 4, and MyD88 in the host response to the fungal pathogen Cryptococcus neoformans in vivo. Infect Immun. 2004 Sep; 72(9):5373-82.
  View in: PubMed
 
44. Mansour MK, Yauch LE, Rottman JB, Levitz SM. Protective efficacy of antigenic fractions in mouse models of cryptococcosis. Infect Immun. 2004 Mar; 72(3):1746-54.
  View in: PubMed
 
45. Bellocchio S, Montagnoli C, Bozza S, Gaziano R, Rossi G, Mambula SS, Vecchi A, Mantovani A, Levitz SM, Romani L. The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol. 2004 Mar 1; 172(5):3059-69.
  View in: PubMed
 
46. Sau K, Mambula SS, Latz E, Henneke P, Golenbock DT, Levitz SM. The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism. J Biol Chem. 2003 Sep 26; 278(39):37561-8.
  View in: PubMed
 
47. Kozel TR, Levitz SM, Dromer F, Gates MA, Thorkildson P, Janbon G. Antigenic and biological characteristics of mutant strains of Cryptococcus neoformans lacking capsular O acetylation or xylosyl side chains. Infect Immun. 2003 May; 71(5):2868-75.
  View in: PubMed
 
48. Huang C, Nong SH, Mansour MK, Specht CA, Levitz SM. Purification and characterization of a second immunoreactive mannoprotein from Cryptococcus neoformans that stimulates T-Cell responses. Infect Immun. 2002 Oct; 70(10):5485-93.
  View in: PubMed
 
49. Mambula SS, Sau K, Henneke P, Golenbock DT, Levitz SM. Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J Biol Chem. 2002 Oct 18; 277(42):39320-6.
  View in: PubMed
 
50. Mansour MK, Levitz SM. Interactions of fungi with phagocytes. Curr Opin Microbiol. 2002 Aug; 5(4):359-65.
  View in: PubMed
 
51. Harrison TS, Chen J, Simons E, Levitz SM. Determination of the pH of the Cryptococcus neoformans vacuole. Med Mycol. 2002 Jun; 40(3):329-32.
  View in: PubMed
 
52. Weber SM, Chen JM, Levitz SM. Inhibition of mitogen-activated protein kinase signaling by chloroquine. J Immunol. 2002 May 15; 168(10):5303-9.
  View in: PubMed
 
53. Mansour MK, Schlesinger LS, Levitz SM. Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors. J Immunol. 2002 Mar 15; 168(6):2872-9.
  View in: PubMed
 
54. Levitz SM. Receptor-mediated recognition of Cryptococcus neoformans. Nippon Ishinkin Gakkai Zasshi. 2002; 43(3):133-6.
  View in: PubMed
 
55. Levitz SM. Does amoeboid reasoning explain the evolution and maintenance of virulence factors in Cryptococcus neoformans? Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26):14760-2.
  View in: PubMed
 
56. Levitz SM. Cryptococcus neoformans: intracellular or extracellular? Trends Microbiol. 2001 Sep; 9(9):417-8.
  View in: PubMed
 
57. Levitz SM, Nong S, Mansour MK, Huang C, Specht CA. Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10422-7.
  View in: PubMed
 
58. Shoham S, Huang C, Chen JM, Golenbock DT, Levitz SM. Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule. J Immunol. 2001 Apr 1; 166(7):4620-6.
  View in: PubMed
 
59. Weber SM, Levitz SM. Chloroquine antagonizes the proinflammatory cytokine response to opportunistic fungi by alkalizing the fungal phagolysosome. J Infect Dis. 2001 Mar 15; 183(6):935-42.
  View in: PubMed
 
60. Mambula SS, Simons ER, Hastey R, Selsted ME, Levitz SM. Human neutrophil-mediated nonoxidative antifungal activity against Cryptococcus neoformans. Infect Immun. 2000 Nov; 68(11):6257-64.
  View in: PubMed
 
61. Ieong MH, Reardon CC, Levitz SM, Kornfeld H. Human immunodeficiency virus type 1 infection of alveolar macrophages impairs their innate fungicidal activity. Am J Respir Crit Care Med. 2000 Sep; 162(3 Pt 1):966-70.
  View in: PubMed
 
62. Weber SM, Levitz SM. Chloroquine interferes with lipopolysaccharide-induced TNF-alpha gene expression by a nonlysosomotropic mechanism. J Immunol. 2000 Aug 1; 165(3):1534-40.
  View in: PubMed
 
63. Weber SM, Levitz SM, Harrison TS. Chloroquine and the fungal phagosome. Curr Opin Microbiol. 2000 Aug; 3(4):349-53.
  View in: PubMed
 
64. Harrison TS, Griffin GE, Levitz SM. Conditional lethality of the diprotic weak bases chloroquine and quinacrine against Cryptococcus neoformans. J Infect Dis. 2000 Jul; 182(1):283-9.
  View in: PubMed
 
65. Shafman TD, Levitz S, Nixon AJ, Gibans LA, Nichols KE, Bell DW, Ishioka C, Isselbacher KJ, Gelman R, Garber J, Harris JR, Haber DA. Prevalence of germline truncating mutations in ATM in women with a second breast cancer after radiation therapy for a contralateral tumor. Genes Chromosomes Cancer. 2000 Feb; 27(2):124-9.
  View in: PubMed
 
66. Nosanchuk JD, Shoham S, Fries BC, Shapiro DS, Levitz SM, Casadevall A. Evidence of zoonotic transmission of Cryptococcus neoformans from a pet cockatoo to an immunocompromised patient. Ann Intern Med. 2000 Feb 1; 132(3):205-8.
  View in: PubMed
 
67. Parayath KE, Harrison TS, Levitz SM. Effect of interleukin (IL)-15 priming on IL-12 and interferon-gamma production by pathogen-stimulated peripheral blood mononuclear cells from human immunodeficiency virus-seropositive and -seronegative donors. J Infect Dis. 2000 Feb; 181(2):733-6.
  View in: PubMed
 
68. Huang C, Levitz SM. Stimulation of macrophage inflammatory protein-1alpha, macrophage inflammatory protein-1beta, and RANTES by Candida albicans and Cryptococcus neoformans in peripheral blood mononuclear cells from persons with and without human immunodeficiency virus infection. J Infect Dis. 2000 Feb; 181(2):791-4.
  View in: PubMed
 
69. Kwon-Chung KJ, Sorrell TC, Dromer F, Fung E, Levitz SM. Cryptococcosis: clinical and biological aspects. Med Mycol. 2000; 38 Suppl 1:205-13.
  View in: PubMed
 
70. Rongrungruang Y, Levitz SM. Interactions of Penicillium marneffei with human leukocytes in vitro. Infect Immun. 1999 Sep; 67(9):4732-6.
  View in: PubMed
 
71. Nichols KE, Levitz S, Shannon KE, Wahrer DC, Bell DW, Chang G, Hegde S, Neuberg D, Shafman T, Tarbell NJ, Mauch P, Ishioka C, Haber DA, Diller L. Heterozygous germline ATM mutations do not contribute to radiation-associated malignancies after Hodgkin's disease. J Clin Oncol. 1999 Apr; 17(4):1259.
  View in: PubMed
 
72. Levitz SM, Nong SH, Seetoo KF, Harrison TS, Speizer RA, Simons ER. Cryptococcus neoformans resides in an acidic phagolysosome of human macrophages. Infect Immun. 1999 Feb; 67(2):885-90.
  View in: PubMed
 
73. Nichols KE, Harkin DP, Levitz S, Krainer M, Kolquist KA, Genovese C, Bernard A, Ferguson M, Zuo L, Snyder E, Buckler AJ, Wise C, Ashley J, Lovett M, Valentine MB, Look AT, Gerald W, Housman DE, Haber DA. Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23):13765-70.
  View in: PubMed
 
74. Levitz SM. Host-fungal interactions in HIV infection. Res Immunol. 1998 May-Jun; 149(4-5):489-93; discussion 516-7.
  View in: PubMed
 
75. Levitz SM. Improvement in CD4+ cell counts despite persistently detectable HIV load. N Engl J Med. 1998 Apr 9; 338(15):1074-5.
  View in: PubMed
 
76. Kappe R, Levitz S, Harrison TS, Ruhnke M, Ampel NM, Just-Nübling G. Recent advances in cryptococcosis, candidiasis and coccidioidomycosis complicating HIV infection. Med Mycol. 1998; 36 Suppl 1:207-15.
  View in: PubMed
 
77. Levitz SM, Harrison TS, Tabuni A, Liu X. Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation. J Clin Invest. 1997 Sep 15; 100(6):1640-6.
  View in: PubMed
 
78. Harrison TS, Nong S, Levitz SM. Induction of human immunodeficiency virus type 1 expression in monocytic cells by Cryptococcus neoformans and Candida albicans. J Infect Dis. 1997 Aug; 176(2):485-91.
  View in: PubMed
 
79. Harrison TS, Levitz SM. Mechanisms of impaired anticryptococcal activity of monocytes from donors infected with human immunodeficiency virus. J Infect Dis. 1997 Aug; 176(2):537-40.
  View in: PubMed
 
80. Levitz SM, North EA. Lymphoproliferation and cytokine profiles in human peripheral blood mononuclear cells stimulated by Cryptococcus neoformans. J Med Vet Mycol. 1997 Jul-Aug; 35(4):229-36.
  View in: PubMed
 
81. Levitz SM, North EA, Jiang Y, Nong SH, Kornfeld H, Harrison TS. Variables affecting production of monocyte chemotactic factor 1 from human leukocytes stimulated with Cryptococcus neoformans. Infect Immun. 1997 Mar; 65(3):903-8.
  View in: PubMed
 
82. Levitz SM, Tabuni A, Kozel TR, MacGill RS, Ingalls RR, Golenbock DT. Binding of Cryptococcus neoformans to heterologously expressed human complement receptors. Infect Immun. 1997 Mar; 65(3):931-5.
  View in: PubMed
 
83. Harrison TS, Levitz SM. Priming with IFN-gamma restores deficient IL-12 production by peripheral blood mononuclear cells from HIV-seropositive donors. J Immunol. 1997 Jan 1; 158(1):459-63.
  View in: PubMed
 
84. Jiang Y, Russell TR, Graves DT, Cheng H, Nong SH, Levitz SM. Monocyte chemoattractant protein 1 and interleukin-8 production in mononuclear cells stimulated by oral microorganisms. Infect Immun. 1996 Nov; 64(11):4450-5.
  View in: PubMed
 
85. Hogan LH, Klein BS, Levitz SM. Virulence factors of medically important fungi. Clin Microbiol Rev. 1996 Oct; 9(4):469-88.
  View in: PubMed
 
86. Harrison TS, Levitz SM. Role of IL-12 in peripheral blood mononuclear cell responses to fungi in persons with and without HIV infection. J Immunol. 1996 Jun 1; 156(11):4492-7.
  View in: PubMed
 
87. Kozel TR, Tabuni A, Young BJ, Levitz SM. Influence of opsonization conditions on C3 deposition and phagocyte binding of large- and small-capsule Cryptococcus neoformans cells. Infect Immun. 1996 Jun; 64(6):2336-8.
  View in: PubMed
 
88. Levitz SM, North EA. gamma Interferon gene expression and release in human lymphocytes directly activated by Cryptococcus neoformans and Candida albicans. Infect Immun. 1996 May; 64(5):1595-9.
  View in: PubMed
 
89. Levitz SM, Tabuni A, Nong SH, Golenbock DT. Effects of interleukin-10 on human peripheral blood mononuclear cell responses to Cryptococcus neoformans, Candida albicans, and lipopolysaccharide. Infect Immun. 1996 Mar; 64(3):945-51.
  View in: PubMed
 
90. Meshulam T, Levitz SM, Christin L, Diamond RD. A simplified new assay for assessment of fungal cell damage with the tetrazolium dye, (2,3)-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanil ide (XTT). J Infect Dis. 1995 Oct; 172(4):1153-6.
  View in: PubMed
 
91. Levitz SM, North EA, Dupont MP, Harrison TS. Mechanisms of inhibition of Cryptococcus neoformans by human lymphocytes. Infect Immun. 1995 Sep; 63(9):3550-4.
  View in: PubMed
 
92. Harrison TS, Kornfeld H, Levitz SM. The effect of infection with human immunodeficiency virus on the anticryptococcal activity of lymphocytes and monocytes. J Infect Dis. 1995 Sep; 172(3):665-71.
  View in: PubMed
 
93. Levitz SM, Mathews HL, Murphy JW. Direct antimicrobial activity of T cells. Immunol Today. 1995 Aug; 16(8):387-91.
  View in: PubMed
 
94. Levitz SM, Tabuni A, Kornfeld H, Reardon CC, Golenbock DT. Production of tumor necrosis factor alpha in human leukocytes stimulated by Cryptococcus neoformans. Infect Immun. 1994 May; 62(5):1975-81.
  View in: PubMed
 
95. Levitz SM. Macrophage-Cryptococcus interactions. Immunol Ser. 1994; 60:533-43.
  View in: PubMed
 
96. Levitz SM, Dupont MP, Smail EH. Direct activity of human T lymphocytes and natural killer cells against Cryptococcus neoformans. Infect Immun. 1994 Jan; 62(1):194-202.
  View in: PubMed
 
97. Levitz SM, Tabuni A, Treseler C. Effect of mannose-binding protein on binding of Cryptococcus neoformans to human phagocytes. Infect Immun. 1993 Nov; 61(11):4891-3.
  View in: PubMed
 
98. Roseff SA, Levitz SM. Effect of endothelial cells on phagocyte-mediated anticryptococcal activity. Infect Immun. 1993 Sep; 61(9):3818-24.
  View in: PubMed
 
99. Levitz SM, Dupont MP. Phenotypic and functional characterization of human lymphocytes activated by interleukin-2 to directly inhibit growth of Cryptococcus neoformans in vitro. J Clin Invest. 1993 Apr; 91(4):1490-8.
  View in: PubMed
 
100. Duncan RA, von Reyn CF, Alliegro GM, Toossi Z, Sugar AM, Levitz SM. Idiopathic CD4+ T-lymphocytopenia--four patients with opportunistic infections and no evidence of HIV infection. N Engl J Med. 1993 Feb 11; 328(6):393-8.
  View in: PubMed
 
101. Wagner RP, Levitz SM, Tabuni A, Kornfeld H. HIV-1 envelope protein (gp120) inhibits the activity of human bronchoalveolar macrophages against Cryptococcus neoformans. Am Rev Respir Dis. 1992 Dec; 146(6):1434-8.
  View in: PubMed
 
102. Levitz SM, Tabuni A, Wagner R, Kornfeld H, Smail EH. Binding of unopsonized Cryptococcus neoformans by human bronchoalveolar macrophages: inhibition by a large-molecular-size serum component. J Infect Dis. 1992 Oct; 166(4):866-73.
  View in: PubMed
 
103. Levitz SM. Overview of host defenses in fungal infections. Clin Infect Dis. 1992 Mar; 14 Suppl 1:S37-42.
  View in: PubMed
 
104. McQuillen DP, Zingman BS, Meunier F, Levitz SM. Invasive infections due to Candida krusei: report of ten cases of fungemia that include three cases of endophthalmitis. Clin Infect Dis. 1992 Feb; 14(2):472-8.
  View in: PubMed
 
105. Kappe R, Levitz SM, Cassone A, Washburn RG. Mechanisms of host defence against fungal infection. J Med Vet Mycol. 1992; 30 Suppl 1:167-77.
  View in: PubMed
 
106. Treseler CB, Maziarz RT, Levitz SM. Biological activity of interleukin-2 bound to Candida albicans. Infect Immun. 1992 Jan; 60(1):183-8.
  View in: PubMed
 
107. Levitz SM. The ecology of Cryptococcus neoformans and the epidemiology of cryptococcosis. Rev Infect Dis. 1991 Nov-Dec; 13(6):1163-9.
  View in: PubMed
 
108. Levitz SM. Activation of human peripheral blood mononuclear cells by interleukin-2 and granulocyte-macrophage colony-stimulating factor to inhibit Cryptococcus neoformans. Infect Immun. 1991 Oct; 59(10):3393-7.
  View in: PubMed
 
109. Xu T, Levitz SM, Diamond RD, Oppenheim FG. Anticandidal activity of major human salivary histatins. Infect Immun. 1991 Aug; 59(8):2549-54.
  View in: PubMed
 
110. Levitz SM, Farrell TP, Maziarz RT. Killing of Cryptococcus neoformans by human peripheral blood mononuclear cells stimulated in culture. J Infect Dis. 1991 May; 163(5):1108-13.
  View in: PubMed
 
111. Levitz SM, Tabuni A. Binding of Cryptococcus neoformans by human cultured macrophages. Requirements for multiple complement receptors and actin. J Clin Invest. 1991 Feb; 87(2):528-35.
  View in: PubMed
 
112. Levitz SM, DiBenedetto DJ, Diamond RD. Inhibition and killing of fungi by the polyamine oxidase-polyamine system. Antifungal activity of the PAO-polyamine system. Antonie Van Leeuwenhoek. 1990 Aug; 58(2):107-14.
  View in: PubMed
 
113. Levitz SM, Farrell TP. Growth inhibition of Cryptococcus neoformans by cultured human monocytes: role of the capsule, opsonins, the culture surface, and cytokines. Infect Immun. 1990 May; 58(5):1201-9.
  View in: PubMed
 
114. Levitz SM, Farrell TP. Human neutrophil degranulation stimulated by Aspergillus fumigatus. J Leukoc Biol. 1990 Feb; 47(2):170-5.
  View in: PubMed
 
115. Kozel TR, Wilson MA, Farrell TP, Levitz SM. Activation of C3 and binding to Aspergillus fumigatus conidia and hyphae. Infect Immun. 1989 Nov; 57(11):3412-7.
  View in: PubMed
 
116. Meshulam T, Levitz SM, Diamond RD, Sugar AM. Effect of cilofungin (LY121019), a fungal cell wall synthesis inhibitor, on interactions of Candida albicans with human neutrophils. J Antimicrob Chemother. 1989 Nov; 24(5):741-5.
  View in: PubMed
 
117. Levitz SM. Aspergillosis. Infect Dis Clin North Am. 1989 Mar; 3(1):1-18.
  View in: PubMed
 
118. Levitz SM, DiBenedetto DJ. Paradoxical role of capsule in murine bronchoalveolar macrophage-mediated killing of Cryptococcus neoformans. J Immunol. 1989 Jan 15; 142(2):659-65.
  View in: PubMed
 
119. Levitz SM, DiBenedetto DJ. Differential stimulation of murine resident peritoneal cells by selectively opsonized encapsulated and acapsular Cryptococcus neoformans. Infect Immun. 1988 Oct; 56(10):2544-51.
  View in: PubMed
 
120. Seibel J, Levitz SM. Minorities in the Journal's advertisements. N Engl J Med. 1988 Jul 7; 319(1):57-8.
  View in: PubMed
 
121. Oppenheim FG, Xu T, McMillian FM, Levitz SM, Diamond RD, Offner GD, Troxler RF. Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans. J Biol Chem. 1988 Jun 5; 263(16):7472-7.
  View in: PubMed
 
122. Levitz SM, Tan OT. Factitious dermatosis masquerading as recurrent herpes zoster. Am J Med. 1988 Apr; 84(4):781-3.
  View in: PubMed
 
123. Levitz SM, Lyman CA, Murata T, Sullivan JA, Mandell GL, Diamond RD. Cytosolic calcium changes in individual neutrophils stimulated by opsonized and unopsonized Candida albicans hyphae. Infect Immun. 1987 Nov; 55(11):2783-8.
  View in: PubMed
 
124. Levitz SM, DiBenedetto DJ, Diamond RD. A rapid fluorescent assay to distinguish attached from phagocytized yeast particles. J Immunol Methods. 1987 Jul 16; 101(1):37-42.
  View in: PubMed
 
125. Levitz SM, Selsted ME, Ganz T, Lehrer RI, Diamond RD. In vitro killing of spores and hyphae of Aspergillus fumigatus and Rhizopus oryzae by rabbit neutrophil cationic peptides and bronchoalveolar macrophages. J Infect Dis. 1986 Sep; 154(3):483-9.
  View in: PubMed
 
126. Levitz SM, Diamond RD. A rapid colorimetric assay of fungal viability with the tetrazolium salt MTT. J Infect Dis. 1985 Nov; 152(5):938-45.
  View in: PubMed
 
127. Levitz SM, Diamond RD. Mechanisms of resistance of Aspergillus fumigatus Conidia to killing by neutrophils in vitro. J Infect Dis. 1985 Jul; 152(1):33-42.
  View in: PubMed
 
128. Waldorf AR, Levitz SM, Diamond RD. In vivo bronchoalveolar macrophage defense against Rhizopus oryzae and Aspergillus fumigatus. J Infect Dis. 1984 Nov; 150(5):752-60.
  View in: PubMed
 
129. Levitz SM, Diamond RD. Killing of Aspergillus fumigatus spores and Candida albicans yeast phase by the iron-hydrogen peroxide-iodide cytotoxic system: comparison with the myeloperoxidase-hydrogen peroxide-halide system. Infect Immun. 1984 Mar; 43(3):1100-2.
  View in: PubMed
 
130. Levitz SM, Diamond RD. Changing patterns of aspergillosis infections. Adv Intern Med. 1984; 30:153-74.
  View in: PubMed
 
For assistance with using Profiles, please refer to the online tutorials or contact UMMS Help Desk or call 508-856-8643.
 
Keyword
Last Name
Institution
    
 
 
 
Keywords   
Cryptococcus neoformans
Cryptococcosis
Dendritic Cells
Antigens, Fungal
Membrane Glycoproteins
See all (487) keywords
Co-Authors  
Golenbock, Douglas
Huang, Haibin
Ostroff, Gary
Specht, Charles
Wang, Jennifer
See all (14) people
Physical Neighbors  
Specht, Charles
Lien, Egil
Chen, Jason
Meng, Jianmin
Finberg, Robert

UMMS Home

Intranet

This is an official Page/Publication of the University of Massachusetts Worcester Campus
Office of the Vice Provost for Research, 55 Lake Ave North, Worcester, Massachusetts 01655
Questions or Comments? Email: publicaffairs@umassmed.edu Phone: 508-856-1572