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1.
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Zou Y, Chiu H, Zinovyeva A, Ambros V, Chuang CF, Chang C. Developmental decline in neuronal regeneration by the progressive change of two intrinsic timers. Science. 2013 Apr 19; 340(6130):372-6.
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2.
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Bossé GD, Rüegger S, Ow MC, Vasquez-Rifo A, Rondeau EL, Ambros VR, Großhans H, Simard MJ. The Decapping Scavenger Enzyme DCS-1 Controls MicroRNA Levels in Caenorhabditis elegans. Mol Cell. 2013 Apr 25; 50(2):281-7.
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3.
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Karp X, Ambros V. Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression in C. elegans. Development. 2012 Jun; 139(12):2177-86.
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4.
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McManus DD, Ambros V. Circulating MicroRNAs in cardiovascular disease. Circulation. 2011 Nov 1; 124(18):1908-10.
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5.
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Ambros V. MicroRNAs and developmental timing. Curr Opin Genet Dev. 2011 Aug; 21(4):511-7.
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6.
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Karp X, Hammell M, Ow MC, Ambros V. Effect of life history on microRNA expression during C. elegans development. RNA. 2011 Apr; 17(4):639-51.
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7.
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Karp X, Ambros V. The Developmental Timing Regulator hbl-1 Modulates the Dauer Formation Decision in Caenorhabditis elegans. Genetics. 2011 Jan; 187(1):345-53.
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8.
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Ambros V. MicroRNAs: genetically sensitized worms reveal new secrets. Curr Biol. 2010 Jul 27; 20(14):R598-600.
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9.
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Zheng G, Ambros V, Li WH. Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent. Silence. 2010; 1(1):9.
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10.
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Ambros V. In the tradition of science: an interview with Victor Ambros. PLoS Genet. 2010; 6(3):e1000853.
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11.
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Ambros V. pRB/CKI pathways at the interface of cell cycle and development. Cell Cycle. 2009 Nov 1; 8(21):3433-4.
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12.
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Hammell CM, Karp X, Ambros V. A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2009 Nov 3; 106(44):18668-73.
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13.
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Hong X, Hammell M, Ambros V, Cohen SM. Immunopurification of Ago1 miRNPs selects for a distinct class of microRNA targets. Proc Natl Acad Sci U S A. 2009 Sep 1; 106(35):15085-90.
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14.
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Zhang L, Hammell M, Kudlow BA, Ambros V, Han M. Systematic analysis of dynamic miRNA-target interactions during C. elegans development. Development. 2009 Sep; 136(18):3043-55.
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15.
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Hammell CM, Lubin I, Boag PR, Blackwell TK, Ambros V. nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell. 2009 Mar 6; 136(5):926-38.
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16.
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Martinez NJ, Ow MC, Reece-Hoyes JS, Barrasa MI, Ambros VR, Walhout AJ. Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity. Genome Res. 2008 Dec; 18(12):2005-15.
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17.
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Ambros V. The evolution of our thinking about microRNAs. Nat Med. 2008 Oct; 14(10):1036-40.
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18.
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Ow MC, Martinez NJ, Olsen PH, Silverman HS, Barrasa MI, Conradt B, Walhout AJ, Ambros V. The FLYWCH transcription factors FLH-1, FLH-2, and FLH-3 repress embryonic expression of microRNA genes in C. elegans. Genes Dev. 2008 Sep 15; 22(18):2520-34.
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19.
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Martinez NJ, Ow MC, Barrasa MI, Hammell M, Sequerra R, Doucette-Stamm L, Roth FP, Ambros VR, Walhout AJ. A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity. Genes Dev. 2008 Sep 15; 22(18):2535-49.
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20.
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Hammell M, Long D, Zhang L, Lee A, Carmack CS, Han M, Ding Y, Ambros V. mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts. Nat Methods. 2008 Sep; 5(9):813-9.
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21.
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Sokol NS, Xu P, Jan YN, Ambros V. Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis. Genes Dev. 2008 Jun 15; 22(12):1591-6.
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22.
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Miska EA, Alvarez-Saavedra E, Abbott AL, Lau NC, Hellman AB, McGonagle SM, Bartel DP, Ambros VR, Horvitz HR. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet. 2007 Dec; 3(12):e215.
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23.
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Hinas A, Reimegård J, Wagner EG, Nellen W, Ambros VR, Söderbom F. The small RNA repertoire of Dictyostelium discoideum and its regulation by components of the RNAi pathway. Nucleic Acids Res. 2007; 35(20):6714-26.
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24.
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Ambros V, Chen X. The regulation of genes and genomes by small RNAs. Development. 2007 May; 134(9):1635-41.
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25.
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Long D, Lee R, Williams P, Chan CY, Ambros V, Ding Y. Potent effect of target structure on microRNA function. Nat Struct Mol Biol. 2007 Apr; 14(4):287-94.
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26.
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Gaur A, Jewell DA, Liang Y, Ridzon D, Moore JH, Chen C, Ambros VR, Israel MA. Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res. 2007 Mar 15; 67(6):2456-68.
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27.
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Ambros V. The 2007 George W. Beadle Medal. Robert K. Herman. Genetics. 2007 Feb; 175(2):465-6.
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28.
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Lee RC, Hammell CM, Ambros V. Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans. RNA. 2006 Apr; 12(4):589-97.
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29.
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Hristova M, Birse D, Hong Y, Ambros V. The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding. Mol Cell Biol. 2005 Dec; 25(24):11059-72.
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30.
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Karp X, Ambros V. Developmental biology. Encountering microRNAs in cell fate signaling. Science. 2005 Nov 25; 310(5752):1288-9.
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31.
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Kuhlmann M, Borisova BE, Kaller M, Larsson P, Stach D, Na J, Eichinger L, Lyko F, Ambros V, Söderbom F, Hammann C, Nellen W. Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi. Nucleic Acids Res. 2005; 33(19):6405-17.
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32.
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Sokol NS, Ambros V. Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth. Genes Dev. 2005 Oct 1; 19(19):2343-54.
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33.
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Abbott AL, Alvarez-Saavedra E, Miska EA, Lau NC, Bartel DP, Horvitz HR, Ambros V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell. 2005 Sep; 9(3):403-14.
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34.
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Ambros V. The functions of animal microRNAs. Nature. 2004 Sep 16; 431(7006):350-5.
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35.
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Pepper AS, McCane JE, Kemper K, Yeung DA, Lee RC, Ambros V, Moss EG. The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin. Development. 2004 May; 131(9):2049-59.
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36.
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Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, Dmitrovsky E, Ambros V. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 2004; 5(3):R13.
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37.
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Lee R, Feinbaum R, Ambros V. A short history of a short RNA. Cell. 2004 Jan 23; 116(2 Suppl):S89-92, 1 p following S96.
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38.
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Ambros V, Lee RC. Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning. Methods Mol Biol. 2004; 265:131-58.
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39.
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Carrington JC, Ambros V. Role of microRNAs in plant and animal development. Science. 2003 Jul 18; 301(5631):336-8.
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40.
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Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V. Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity. Dev Biol. 2003 Jul 1; 259(1):9-18.
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41.
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Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell. 2003 Jun 13; 113(6):673-6.
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42.
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Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D. MicroRNAs and other tiny endogenous RNAs in C. elegans. Curr Biol. 2003 May 13; 13(10):807-18.
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43.
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Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T. A uniform system for microRNA annotation. RNA. 2003 Mar; 9(3):277-9.
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44.
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Sempere LF, Dubrovsky EB, Dubrovskaya VA, Berger EM, Ambros V. The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster. Dev Biol. 2002 Apr 1; 244(1):170-9.
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45.
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Ambros V. microRNAs: tiny regulators with great potential. Cell. 2001 Dec 28; 107(7):823-6.
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46.
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Lee RC, Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science. 2001 Oct 26; 294(5543):862-4.
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47.
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Ambros V. Development. Dicing up RNAs. Science. 2001 Aug 3; 293(5531):811-3.
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48.
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Ambros V. The temporal control of cell cycle and cell fate in Caenorhabditis elegans. Novartis Found Symp. 2001; 237:203-14; discussion 214-20.
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49.
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Ambros V. Control of developmental timing in Caenorhabditis elegans. Curr Opin Genet Dev. 2000 Aug; 10(4):428-33.
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50.
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Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell. 2000 Apr; 5(4):659-69.
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51.
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Hong Y, Lee RC, Ambros V. Structure and function analysis of LIN-14, a temporal regulator of postembryonic developmental events in Caenorhabditis elegans. Mol Cell Biol. 2000 Mar; 20(6):2285-95.
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52.
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Olsen PH, Ambros V. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev Biol. 1999 Dec 15; 216(2):671-80.
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53.
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Feinbaum R, Ambros V. The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans. Dev Biol. 1999 Jun 1; 210(1):87-95.
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54.
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Ambros V. Cell cycle-dependent sequencing of cell fate decisions in Caenorhabditis elegans vulva precursor cells. Development. 1999 May; 126(9):1947-56.
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55.
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Hong Y, Roy R, Ambros V. Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans. Development. 1998 Sep; 125(18):3585-97.
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56.
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Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell. 1997 Mar 7; 88(5):637-46.
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57.
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Euling S, Ambros V. Reversal of cell fate determination in Caenorhabditis elegans vulval development. Development. 1996 Aug; 122(8):2507-15.
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58.
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Euling S, Ambros V. Heterochronic genes control cell cycle progress and developmental competence of C. elegans vulva precursor cells. Cell. 1996 Mar 8; 84(5):667-76.
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59.
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Liu Z, Kirch S, Ambros V. The Caenorhabditis elegans heterochronic gene pathway controls stage-specific transcription of collagen genes. Development. 1995 Aug; 121(8):2471-8.
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60.
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Rougvie AE, Ambros V. The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans. Development. 1995 Aug; 121(8):2491-500.
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61.
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Ambros V, Moss EG. Heterochronic genes and the temporal control of C. elegans development. Trends Genet. 1994 Apr; 10(4):123-7.
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62.
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Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993 Dec 3; 75(5):843-54.
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63.
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Mello CC, Kramer JM, Stinchcomb D, Ambros V. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 1991 Dec; 10(12):3959-70.
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64.
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Papp A, Rougvie AE, Ambros V. Molecular cloning of lin-29, a heterochronic gene required for the differentiation of hypodermal cells and the cessation of molting in C.elegans. Nucleic Acids Res. 1991 Feb 11; 19(3):623-30.
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65.
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Liu ZC, Ambros V. Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans. Genes Dev. 1989 Dec; 3(12B):2039-49.
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66.
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Hodgkin J, Papp A, Pulak R, Ambros V, Anderson P. A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics. 1989 Oct; 123(2):301-13.
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67.
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Ambros V. A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans. Cell. 1989 Apr 7; 57(1):49-57.
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68.
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Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR. Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14. Genetics. 1989 Mar; 121(3):501-16.
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69.
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Ambros V, Horvitz HR. The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events. Genes Dev. 1987 Jun; 1(4):398-414.
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70.
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Ambros V, Horvitz HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science. 1984 Oct 26; 226(4673):409-16.
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71.
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Ambros V, Baltimore D. Purification and properties of a HeLa cell enzyme able to remove the 5'-terminal protein from poliovirus RNA. J Biol Chem. 1980 Jul 25; 255(14):6739-44.
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72.
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Ambros V, Pettersson RF, Baltimore D. An enzymatic activity in uninfected cells that cleaves the linkage between poliovirion RNA and the 5' terminal protein. Cell. 1978 Dec; 15(4):1439-46.
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73.
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Ambros V, Baltimore D. Protein is linked to the 5' end of poliovirus RNA by a phosphodiester linkage to tyrosine. J Biol Chem. 1978 Aug 10; 253(15):5263-6.
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74.
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Pettersson RF, Ambros V, Baltimore D. Identification of a protein linked to nascent poliovirus RNA and to the polyuridylic acid of negative-strand RNA. J Virol. 1978 Aug; 27(2):357-65.
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75.
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Hewlett MJ, Rozenblatt S, Ambros V, Baltimore D. Separation and quantitation of intracellular forms of poliovirus RNA by agarose gel electrophoresis. Biochemistry. 1977 Jun 14; 16(12):2763-7.
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76.
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Flanegan JB, Petterson RF, Ambros V, Hewlett NJ, Baltimore D. Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus. Proc Natl Acad Sci U S A. 1977 Mar; 74(3):961-5.
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77.
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Ambros VR, Chen LB, Buchanan JM. Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus. Proc Natl Acad Sci U S A. 1975 Aug; 72(8):3144-8.
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78.
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Gruberg ER, Ambros VR. A forebrain visual projection in the frog (Rana pipiens). Exp Neurol. 1974 Aug; 44(2):187-97.
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