Karl K McKinstry PHD
Title Instructor
Institution University of Massachusetts Medical School
Department Pathology
Division Academic Pathology
Address University of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
Email
Publications
1. Hamada H, Bassity E, Flies A, Strutt TM, Garcia-Hernandez Mde L, McKinstry KK, Zou T, Swain SL, Dutton RW. Multiple Redundant Effector Mechanisms of CD8+ T Cells Protect against Influenza Infection. J Immunol. 2013 Jan 1; 190(1):296-306.
  View in: PubMed
 
2. Strutt TM, McKinstry KK, Kuang Y, Bradley LM, Swain SL. Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):E2551-60.
  View in: PubMed
 
3. McKinstry KK, Strutt TM, Kuang Y, Brown DM, Sell S, Dutton RW, Swain SL. Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms. J Clin Invest. 2012 Aug 1; 122(8):2847-56.
  View in: PubMed
 
4. Swain SL, McKinstry KK, Strutt TM. Expanding roles for CD4(+) T cells in immunity to viruses. Nat Rev Immunol. 2012; 12(2):136-48.
  View in: PubMed
 
5. McKinstry KK, Strutt TM, Swain SL. Hallmarks of CD4 T cell immunity against influenza. J Intern Med. 2011 May; 269(5):507-18.
  View in: PubMed
 
6. Strutt TM, McKinstry KK, Swain SL. Control of innate immunity by memory CD4 T cells. Adv Exp Med Biol. 2011; 780:57-68.
  View in: PubMed
 
7. McKinstry KK, Strutt TM, Swain SL. Regulation of CD4+ T-cell contraction during pathogen challenge. Immunol Rev. 2010 Jul; 236:110-24.
  View in: PubMed
 
8. Strutt TM, McKinstry KK, Dibble JP, Winchell C, Kuang Y, Curtis JD, Huston G, Dutton RW, Swain SL. Memory CD4+ T cells induce innate responses independently of pathogen. Nat Med. 2010 May; 16(5):558-64, 1p following 564.
  View in: PubMed
 
9. McKinstry KK, Strutt TM, Swain SL. The potential of CD4 T-cell memory. Immunology. 2010 May; 130(1):1-9.
  View in: PubMed
 
10. McKinstry KK, Strutt TM, Buck A, Curtis JD, Dibble JP, Huston G, Tighe M, Hamada H, Sell S, Dutton RW, Swain SL. IL-10 deficiency unleashes an influenza-specific Th17 response and enhances survival against high-dose challenge. J Immunol. 2009 Jun 15; 182(12):7353-63.
  View in: PubMed
 
11. Hamada H, Garcia-Hernandez Mde L, Reome JB, Misra SK, Strutt TM, McKinstry KK, Cooper AM, Swain SL, Dutton RW. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J Immunol. 2009 Mar 15; 182(6):3469-81.
  View in: PubMed
 
12. Strutt TM, McKinstry KK, Swain SL. Functionally diverse subsets in CD4 T cell responses against influenza. J Clin Immunol. 2009 Mar; 29(2):145-50.
  View in: PubMed
 
13. Jelley-Gibbs DM, Strutt TM, McKinstry KK, Swain SL. Influencing the fates of CD4 T cells on the path to memory: lessons from influenza. Immunol Cell Biol. 2008 May-Jun; 86(4):343-52.
  View in: PubMed
 
14. McKinstry KK, Strutt TM, Swain SL. The effector to memory transition of CD4 T cells. Immunol Res. 2008; 40(2):114-27.
  View in: PubMed
 
15. McKinstry KK, Golech S, Lee WH, Huston G, Weng NP, Swain SL. Rapid default transition of CD4 T cell effectors to functional memory cells. J Exp Med. 2007 Sep 3; 204(9):2199-211.
  View in: PubMed
 
16. Li X, McKinstry KK, Swain SL, Dalton DK. IFN-gamma acts directly on activated CD4+ T cells during mycobacterial infection to promote apoptosis by inducing components of the intracellular apoptosis machinery and by inducing extracellular proapoptotic signals. J Immunol. 2007 Jul 15; 179(2):939-49.
  View in: PubMed
 
17. Jelley-Gibbs DM, Dibble JP, Brown DM, Strutt TM, McKinstry KK, Swain SL. Persistent depots of influenza antigen fail to induce a cytotoxic CD8 T cell response. J Immunol. 2007 Jun 15; 178(12):7563-70.
  View in: PubMed
 
18. Swain SL, Agrewala JN, Brown DM, Jelley-Gibbs DM, Golech S, Huston G, Jones SC, Kamperschroer C, Lee WH, McKinstry KK, Román E, Strutt T, Weng NP. CD4+ T-cell memory: generation and multi-faceted roles for CD4+ T cells in protective immunity to influenza. Immunol Rev. 2006 Jun; 211:8-22.
  View in: PubMed
 
19. Strutt TM, Uzonna J, McKinstry KK, Bretscher PA. Activation of thymic T cells by MHC alloantigen requires syngeneic, activated CD4+ T cells and B cells as APC. Int Immunol. 2006 May; 18(5):719-28.
  View in: PubMed
 
For assistance with using Profiles, please refer to the online tutorials or contact UMMS Help Desk or call 508-856-8643.
 
Keyword
Last Name
Institution
    
 
 
 
Co-Authors  
Dutton, Richard
Strutt, Tara
Swain, Susan
See all (3) people
Physical Neighbors  
Chan, Francis Ka Ming
Silverman, Jerald
Kang, Joonsoo
Welsh, Raymond
Strutt, Tara

UMMS Home

Intranet

This is an official Page/Publication of the University of Massachusetts Worcester Campus
Office of the Vice Provost for Research, 55 Lake Ave North, Worcester, Massachusetts 01655
Questions or Comments? Email: publicaffairs@umassmed.edu Phone: 508-856-1572