Sally C Kent PHD
Title Assistant Professor
Institution University of Massachusetts Medical School
Department Medicine
Division Diabetes
Address University of Massachusetts Medical School
381 Plantation Street
Worcester MA 01605
Telephone 508-856-2044
Email
Publications
1. Raddassi K, Kent SC, Yang J, Bourcier K, Bradshaw EM, Seyfert-Margolis V, Nepom GT, Kwok WW, Hafler DA. Increased Frequencies of Myelin Oligodendrocyte Glycoprotein/MHC Class II-Binding CD4 Cells in Patients with Multiple Sclerosis. J Immunol. 2011 Jul 15; 187(2):1039-46.
  View in: PubMed
 
2. Song Q, Han Q, Bradshaw EM, Kent SC, Raddassi K, Nilsson B, Nepom GT, Hafler DA, Love JC. On-chip activation and subsequent detection of individual antigen-specific T cells. Anal Chem. 2010 Jan 15; 82(2):473-7.
  View in: PubMed
 
3. Sharma AK, Ling Y, Greer AB, Hafler DA, Kent SC, Zhang Y, Rigby AC. Evaluating the intrinsic cysteine redox-dependent states of the A-chain of human insulin using NMR spectroscopy, quantum chemical calculations, and mass spectrometry. J Phys Chem B. 2010 Jan 14; 114(1):585-91.
  View in: PubMed
 
4. Gianani R, Campbell-Thompson M, Sarkar SA, Wasserfall C, Pugliese A, Solis JM, Kent SC, Hering BJ, West E, Steck A, Bonner-Weir S, Atkinson MA, Coppieters K, von Herrath M, Eisenbarth GS. Dimorphic histopathology of long-standing childhood-onset diabetes. Diabetologia. 2010 Apr; 53(4):690-8.
  View in: PubMed
 
5. Bradshaw EM, Raddassi K, Elyaman W, Orban T, Gottlieb PA, Kent SC, Hafler DA. Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells. J Immunol. 2009 Oct 1; 183(7):4432-9.
  View in: PubMed
 
6. Hastings WD, Anderson DE, Kassam N, Koguchi K, Greenfield EA, Kent SC, Zheng XX, Strom TB, Hafler DA, Kuchroo VK. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol. 2009 Sep; 39(9):2492-501.
  View in: PubMed
 
7. Bradshaw EM, Kent SC, Tripuraneni V, Orban T, Ploegh HL, Hafler DA, Love JC. Concurrent detection of secreted products from human lymphocytes by microengraving: cytokines and antigen-reactive antibodies. Clin Immunol. 2008 Oct; 129(1):10-8.
  View in: PubMed
 
8. Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11281-6.
  View in: PubMed
 
9. Smith RN, Kent SC, Nagle J, Selig M, Iafrate AJ, Najafian N, Hafler DA, Auchincloss H, Orban T, Cagliero E. Pathology of an islet transplant 2 years after transplantation: evidence for a nonimmunological loss. Transplantation. 2008 Jul 15; 86(1):54-62.
  View in: PubMed
 
10. Waziri A, Killory B, Ogden AT, Canoll P, Anderson RC, Kent SC, Anderson DE, Bruce JN. Preferential in situ CD4+CD56+ T cell activation and expansion within human glioblastoma. J Immunol. 2008 Jun 1; 180(11):7673-80.
  View in: PubMed
 
11. Costantino CM, Hang HC, Kent SC, Hafler DA, Ploegh HL. Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation. J Immunol. 2008 Mar 1; 180(5):2876-85.
  View in: PubMed
 
12. Kis J, Engelmann P, Farkas K, Richman G, Eck S, Lolley J, Jalahej H, Borowiec M, Kent SC, Treszl A, Orban T. Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus. J Leukoc Biol. 2007 Mar; 81(3):654-62.
  View in: PubMed
 
13. van den Elzen P, Garg S, León L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 2005 Oct 6; 437(7060):906-10.
  View in: PubMed
 
14. Kent SC, Chen Y, Clemmings SM, Viglietta V, Kenyon NS, Ricordi C, Hering B, Hafler DA. Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells. J Immunol. 2005 Oct 1; 175(7):4458-64.
  View in: PubMed
 
15. Quintana FJ, Gerber D, Kent SC, Cohen IR, Shai Y. HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation. J Clin Invest. 2005 Aug; 115(8):2149-58.
  View in: PubMed
 
16. Kent SC, Chen Y, Bregoli L, Clemmings SM, Kenyon NS, Ricordi C, Hering BJ, Hafler DA. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope. Nature. 2005 May 12; 435(7039):224-8.
  View in: PubMed
 
17. Brigl M, Bry L, Kent SC, Gumperz JE, Brenner MB. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat Immunol. 2003 Dec; 4(12):1230-7.
  View in: PubMed
 
18. Viglietta V, Kent SC, Orban T, Hafler DA. GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes. J Clin Invest. 2002 Apr; 109(7):895-903.
  View in: PubMed
 
19. Orban T, Kent SC, Malik P, Milner JD, Schuster K, Jackson RA, Hafler DA. Heterophile antibodies indicate progression of autoimmunity in human type 1 diabetes mellitus before clinical onset. Autoimmunity. 2001; 34(4):247-64.
  View in: PubMed
 
20. Wilson SB, Kent SC, Horton HF, Hill AA, Bollyky PL, Hafler DA, Strominger JL, Byrne MC. Multiple differences in gene expression in regulatory Valpha 24Jalpha Q T cells from identical twins discordant for type I diabetes. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7411-6.
  View in: PubMed
 
21. Kent SC, Hafler DA, Strominger JL, Wilson SB. Noncanonical Valpha24JalphaQ T cells with conservative alpha chain CDR3 region amino acid substitutions are restricted by CD1d. Hum Immunol. 1999 Nov; 60(11):1080-9.
  View in: PubMed
 
22. Milner JD, Kent SC, Ashley TA, Wilson SB, Strominger JL, Hafler DA. Differential responses of invariant V alpha 24J alpha Q T cells and MHC class II-restricted CD4+ T cells to dexamethasone. J Immunol. 1999 Sep 1; 163(5):2522-9.
  View in: PubMed
 
23. She JX, Ellis TM, Wilson SB, Wasserfall CH, Marron M, Reimsneider S, Kent SC, Hafler DA, Neuberg DS, Muir A, Strominger JL, Atkinson MA. Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes. Proc Natl Acad Sci U S A. 1999 Jul 6; 96(14):8116-9.
  View in: PubMed
 
24. Wilson SB, Kent SC, Patton KT, Orban T, Jackson RA, Exley M, Porcelli S, Schatz DA, Atkinson MA, Balk SP, Strominger JL, Hafler DA. Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes. Nature. 1998 Jan 8; 391(6663):177-81.
  View in: PubMed
 
25. Hafler DA, Kent SC, Pietrusewicz MJ, Khoury SJ, Weiner HL, Fukaura H. Oral administration of myelin induces antigen-specific TGF-beta 1 secreting T cells in patients with multiple sclerosis. Ann N Y Acad Sci. 1997 Dec 19; 835:120-31.
  View in: PubMed
 
26. Kent SC, Fukaura H, Pietrusewicz MJ, Khoury SJ, Weiner HL, Hafler DA. Oral administration of myelin induces antigen-specific TGF-beta 1-secreting T cells in multiple sclerosis patients. Ann N Y Acad Sci. 1997 Apr 5; 815:412-22.
  View in: PubMed
 
27. Fukaura H, Kent SC, Pietrusewicz MJ, Khoury SJ, Weiner HL, Hafler DA. Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. J Clin Invest. 1996 Jul 1; 98(1):70-7.
  View in: PubMed
 
28. Fukaura H, Kent SC, Pietrusewicz MJ, Khoury SJ, Weiner HL, Hafler DA. Antigen-specific TGF-beta1 secretion with bovine myelin oral tolerization in multiple sclerosis. Ann N Y Acad Sci. 1996 Feb 13; 778:251-7.
  View in: PubMed
 
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Keyword
Last Name
Institution
    
 
 
 
Keywords   
Diabetes Mellitus, Type 1
T-Lymphocyte Subsets
Lymph Nodes
T-Lymphocytes
Pancreas
See all (202) keywords
Physical Neighbors  
Trivedi, Chinmay
Tanriverdi, Kahraman
Pechhold, Klaus
Beaulieu, Lea
Cooper, Marcus

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