Frederick Spencer MD
Title Associate Professor
Institution University of Massachusetts Medical School
Department Medicine
Division Cardiovascular Medicine
Address St. Josephs Healthcare Hamilton
50 Charlton Avenue E, Martha Wing-H319
Hamilton ON L8N4A6
Telephone 905-521-2100 x76973
Email
Publications
1. Joffe SW, Dewolf M, Shih J, McManus DD, Spencer FA, Lessard D, Gore JM, Goldberg RJ. Trends in the medical management of patients with heart failure. J Clin Med Res. 2013 Jun; 5(3):194-204.
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2. Linkins LA, Bates SM, Lang E, Kahn SR, Douketis JD, Julian J, Parpia S, Gross P, Weitz JI, Spencer FA, Lee AY, O'Donnell MJ, Crowther MA, Chan HH, Lim W, Schulman S, Ginsberg JS, Kearon C. Selective d-Dimer Testing for Diagnosis of a First Suspected Episode of Deep Venous Thrombosis: A Randomized Trial. Ann Intern Med. 2013 Jan 15; 158(2):93-100.
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3. Chan WS, Spencer FA, Lee AY, Chunilal S, Douketis JD, Rodger M, Ginsberg JS. Safety of withholding anticoagulation in pregnant women with suspected deep vein thrombosis following negative serial compression ultrasound and iliac vein imaging. CMAJ. 2013 Mar 5; 185(4):E194-200.
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4. Pai M, Lloyd NS, Cheng J, Thabane L, Spencer FA, Cook DJ, Haynes RB, Schünemann HJ, Douketis JD. Strategies to enhance venous thromboprophylaxis in hospitalized medical patients (SENTRY): a pilot cluster randomized trial. Implement Sci. 2013; 8:1.
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5. Huang W, Anderson FA, Spencer FA, Gallus A, Goldberg RJ. Risk-assessment models for predicting venous thromboembolism among hospitalized non-surgical patients: a systematic review. J Thromb Thrombolysis. 2013 Jan; 35(1):67-80.
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6. Spencer FA, Iorio A, You J, Murad MH, Schünemann HJ, Vandvik PO, Crowther MA, Pottie K, Lang ES, Meerpohl JJ, Falck-Ytter Y, Alonso-Coello P, Guyatt GH. Uncertainties in baseline risk estimates and confidence in treatment effects. BMJ. 2012; 345:e7401.
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7. Mortazavi M, Samiee MM, Spencer FA. Incidence of deep vein thrombosis in erysipelas or cellulitis of the lower extremities. Int J Dermatol. 2013 Mar; 52(3):279-85.
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8. Piazza G, Goldhaber SZ, Kroll A, Goldberg RJ, Emery C, Spencer FA. Venous thromboembolism in patients with chronic obstructive pulmonary disease. Am J Med. 2012 Oct; 125(10):1010-8.
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9. Vandvik PO, Santesso N, Akl EA, You J, Mulla S, Spencer FA, Johnston BC, Brozek J, Kreis J, Brandt L, Zhou Q, Schünemann HJ, Guyatt G. Formatting modifications in GRADE evidence profiles improved guideline panelists comprehension and accessibility to information. A randomized trial. J Clin Epidemiol. 2012 Jul; 65(7):748-55.
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10. Piazza G, Goldhaber SZ, Kroll A, Goldberg RJ, Emery C, Spencer FA. Venous thromboembolism in patients with diabetes mellitus. Am J Med. 2012 Jul; 125(7):709-16.
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11. Warkentin AE, Donadini MP, Spencer FA, Lim W, Crowther M. Bleeding risk in randomized controlled trials comparing warfarin and aspirin: a systematic review and meta-analysis. J Thromb Haemost. 2012 Apr; 10(4):512-20.
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12. Spencer FA, Kroll A, Lessard D, Emery C, Glushchenko AV, Pacifico L, Reed G, Gore JM, Goldberg RJ. Isolated calf deep vein thrombosis in the community setting: the Worcester Venous Thromboembolism study. J Thromb Thrombolysis. 2012 Apr; 33(3):211-7.
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13. Al Khdair D, Alshengeiti L, Elbarouni B, Yan RT, Grondin FR, Spencer FA, Pallie S, Brieger D, Eagle KA, Mangat I, Singh S, Goodman SG, Yan AT. Management and outcome of acute coronary syndrome patients in relation to prior history of atrial fibrillation. Can J Cardiol. 2012 Jul; 28(4):443-9.
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14. Elbarouni B, Banihashemi SB, Yan RT, Welsh RC, Kornder JM, Wong GC, Anderson FA, Spencer FA, Grondin FR, Goodman SG, Yan AT. Temporal Patterns of Lipid Testing and Statin Therapy in Acute Coronary Syndrome Patients (from the Canadian GRACE Experience). Am J Cardiol. 2012 May 15; 109(10):1418-24.
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15. Douketis JD, Spyropoulos AC, Spencer FA, Mayr M, Jaffer AK, Eckman MH, Dunn AS, Kunz R. Perioperative Management of Antithrombotic Therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb; 141(2 Suppl):e326S-50S.
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16. You JJ, Singer DE, Howard PA, Lane DA, Eckman MH, Fang MC, Hylek EM, Schulman S, Go AS, Hughes M, Spencer FA, Manning WJ, Halperin JL, Lip GY. Antithrombotic Therapy for Atrial Fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb; 141(2 Suppl):e531S-75S.
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17. Lansberg MG, O'Donnell MJ, Khatri P, Lang ES, Nguyen-Huynh MN, Schwartz NE, Sonnenberg FA, Schulman S, Vandvik PO, Spencer FA, Alonso-Coello P, Guyatt GH, Akl EA. Antithrombotic and Thrombolytic Therapy for Ischemic Stroke: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb; 141(2 Suppl):e601S-36S.
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18. Vandvik PO, Lincoff AM, Gore JM, Gutterman DD, Sonnenberg FA, Alonso-Coello P, Akl EA, Lansberg MG, Guyatt GH, Spencer FA. Primary and Secondary Prevention of Cardiovascular Disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb; 141(2 Suppl):e637S-68S.
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19. Alonso-Coello P, Bellmunt S, McGorrian C, Anand SS, Guzman R, Criqui MH, Akl EA, Olav Vandvik P, Lansberg MG, Guyatt GH, Spencer FA. Antithrombotic Therapy in Peripheral Artery Disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb; 141(2 Suppl):e669S-90S.
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20. Eikelboom JW, Hirsh J, Spencer FA, Baglin TP, Weitz JI. Antiplatelet Drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb; 141(2 Suppl):e89S-e119S.
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21. Piazza G, Goldhaber SZ, Lessard DM, Goldberg RJ, Emery C, Spencer FA. Venous thromboembolism in patients with symptomatic atherosclerosis. Thromb Haemost. 2011 Nov 30; 106(6):1095-102.
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22. Nguyen HL, Saczynski JS, Gore JM, Waring ME, Lessard D, Yarzebski J, Reed G, Spencer FA, Li SX, Goldberg RJ. Long-term Trends in Short-term Outcomes in Acute Myocardial Infarction. Am J Med. 2011 Oct; 124(10):939-46.
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23. Parikh AM, Spencer FA, Lessard D, Emery C, Baylin A, Linkletter C, Goldberg RJ. Venous Thromboembolism in Patients With Reduced Estimated GFR: A Population-Based Perspective. Am J Kidney Dis. 2011 Nov; 58(5):746-55.
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24. McManus DD, Piacentine SM, Lessard D, Gore JM, Yarzebski J, Spencer FA, Goldberg RJ. Thirty-year (1975 to 2005) trends in the incidence rates, clinical features, treatment practices, and short-term outcomes of patients <55 years of age hospitalized with an initial acute myocardial infarction. Am J Cardiol. 2011 Aug 15; 108(4):477-82.
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25. Spyropoulos AC, Anderson FA, Fitzgerald G, Decousus H, Pini M, Chong BH, Zotz RB, Bergmann JF, Tapson V, Froehlich JB, Monreal M, Merli GJ, Pavanello R, Turpie AG, Nakamura M, Piovella F, Kakkar AK, Spencer FA. Predictive and associative models to identify hospitalized medical patients at risk for VTE. Chest. 2011 Sep; 140(3):706-14.
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26. Piazza G, Goldhaber SZ, Lessard DM, Goldberg RJ, Emery C, Spencer FA. Venous thromboembolism in heart failure: preventable deaths during and after hospitalization. Am J Med. 2011 Mar; 124(3):252-9.
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27. Spencer FA, Ginberg JS. Recurrence after unprovoked venous thromboembolism. BMJ. 2011; 342:d611.
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28. McManus DD, Chinali M, Saczynski JS, Gore JM, Yarzebski J, Spencer FA, Lessard D, Goldberg RJ. 30-year trends in heart failure in patients hospitalized with acute myocardial infarction. Am J Cardiol. 2011 Feb 1; 107(3):353-9.
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29. McManus DD, Gore J, Yarzebski J, Spencer F, Lessard D, Goldberg RJ. Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI. Am J Med. 2011 Jan; 124(1):40-7.
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30. Saczynski JS, Lessard D, Spencer FA, Gurwitz JH, Gore JM, Yarzebski J, Goldberg RJ. Declining length of stay for patients hospitalized with AMI: impact on mortality and readmissions. Am J Med. 2010 Nov; 123(11):1007-15.
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31. Nguyen HL, Gore JM, Saczynski JS, Yarzebski J, Reed G, Spencer FA, Goldberg RJ. Age and sex differences and 20-year trends (1986 to 2005) in prehospital delay in patients hospitalized with acute myocardial infarction. Circ Cardiovasc Qual Outcomes. 2010 Nov 1; 3(6):590-8.
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32. Spencer FA, Bates SM, Goldberg RJ, Lessard D, Emery C, Glushchenko A, Gore JM, White RH. A population-based study of inferior vena cava filters in patients with acute venous thromboembolism. Arch Intern Med. 2010 Sep 13; 170(16):1456-62.
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33. Nguyen HL, Goldberg RJ, Gore JM, Fox KA, Eagle KA, Gurfinkel EP, Spencer FA, Reed G, Quill A, Anderson FA. Age and sex differences, and changing trends, in the use of evidence-based therapies in acute coronary syndromes: perspectives from a multinational registry. Coron Artery Dis. 2010 Sep; 21(6):336-44.
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34. Elbarouni B, Elmanfud O, Yan RT, Fox KA, Kornder JM, Rose B, Spencer FA, Welsh RC, Wong GC, Goodman SG, Yan AT. Temporal trend of in-hospital major bleeding among patients with non ST-elevation acute coronary syndromes. Am Heart J. 2010 Sep; 160(3):420-7.
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35. Spencer FA, Goldberg RJ, Lessard D, Reed G, Emery C, Gore JM, Pacifico L, Weitz JI. Factors associated with adverse outcomes in outpatients presenting with pulmonary embolism: the Worcester Venous Thromboembolism Study. Circ Cardiovasc Qual Outcomes. 2010 Jul; 3(4):390-4.
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36. Goldberg RJ, Spencer FA, Szklo-Coxe M, Tisminetzky M, Yarzebski J, Lessard D, Gore JM, Gaasch W. Symptom presentation in patients hospitalized with acute heart failure. Clin Cardiol. 2010 Jun; 33(6):E73-80.
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37. Decousus H, Tapson VF, Bergmann JF, Chong BH, Froehlich JB, Kakkar AK, Merli GJ, Monreal M, Nakamura M, Pavanello R, Pini M, Piovella F, Spencer FA, Spyropoulos AC, Turpie AG, Zotz RB, Fitzgerald G, Anderson FA. Factors at admission associated with bleeding risk in medical patients: findings from the IMPROVE investigators. Chest. 2011 Jan; 139(1):69-79.
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38. Chan WS, Spencer FA, Ginsbergm JS. Anatomic distribution of deep vein thrombosis in pregnancy. CMAJ. 2010 Apr 20; 182(7):657-60.
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39. Spencer FA, Montalescot G, Fox KA, Goodman SG, Granger CB, Goldberg RJ, Oliveira GB, Anderson FA, Eagle KA, Fitzgerald G, Gore JM. Delay to reperfusion in patients with acute myocardial infarction presenting to acute care hospitals: an international perspective. Eur Heart J. 2010 Jun; 31(11):1328-36.
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40. Fornasini M, Yarzebski J, Chiriboga D, Lessard D, Spencer FA, Aurigemma P, Gore JM, Goldberg RJ. Contemporary trends in evidence-based treatment for acute myocardial infarction. Am J Med. 2010 Feb; 123(2):166-72.
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41. Chan WS, Lee A, Spencer FA, Chunilal S, Crowther M, Wu W, Johnston M, Rodger M, Ginsberg JS. D-dimer testing in pregnant patients: towards determining the next 'level' in the diagnosis of deep vein thrombosis. J Thromb Haemost. 2010 May; 8(5):1004-11.
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42. Schulman S, Spencer FA. Antithrombotic drugs in coronary artery disease: risk benefit ratio and bleeding. J Thromb Haemost. 2010 Apr; 8(4):641-50.
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43. Becker RC, Scheiman J, Dauerman HL, Spencer F, Rao S, Sabatine M, Johnson DA, Chan F, Abraham NS, Quigley EM. Management of platelet-directed pharmacotherapy in patients with atherosclerotic coronary artery disease undergoing elective endoscopic gastrointestinal procedures. J Am Coll Cardiol. 2009 Dec 8; 54(24):2261-76.
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44. Becker RC, Scheiman J, Dauerman HL, Spencer F, Rao S, Sabatine M, Johnson DA, Chan F, Abraham NS, Quigley EM. Management of platelet-directed pharmacotherapy in patients with atherosclerotic coronary artery disease undergoing elective endoscopic gastrointestinal procedures. Am J Gastroenterol. 2009 Dec; 104(12):2903-17.
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45. Spencer FA, Emery C, Joffe SW, Pacifico L, Lessard D, Reed G, Gore JM, Goldberg RJ. Incidence rates, clinical profile, and outcomes of patients with venous thromboembolism. The Worcester VTE study. J Thromb Thrombolysis. 2009 Nov; 28(4):401-9.
  View in: PubMed
 
46. Saczynski JS, Darling CE, Spencer FA, Lessard D, Gore JM, Goldberg RJ. Clinical features, treatment practices, and hospital and long-term outcomes of older patients hospitalized with decompensated heart failure: The Worcester Heart Failure Study. J Am Geriatr Soc. 2009 Sep; 57(9):1587-94.
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47. Chan WS, Lee A, Spencer FA, Crowther M, Rodger M, Ramsay T, Ginsberg JS. Predicting deep venous thrombosis in pregnancy: out in "LEFt" field? Ann Intern Med. 2009 Jul 21; 151(2):85-92.
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48. Goldberg RJ, Darling C, Joseph B, Saczynski J, Chinali M, Lessard D, Pezzella S, Spencer FA. Epidemiology of decompensated heart failure in a single community in the northeastern United States. Am J Cardiol. 2009 Aug 1; 104(3):377-82.
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49. Saczynski JS, McManus D, Zhou Z, Spencer F, Yarzebski J, Lessard D, Gore JM, Goldberg RJ. Trends in atrial fibrillation complicating acute myocardial infarction. Am J Cardiol. 2009 Jul 15; 104(2):169-74.
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50. Spencer FA, Gore JM, Reed G, Lessard D, Pacifico L, Emery C, Crowther MA, Goldberg RJ. Venous thromboembolism and bleeding in a community setting. The Worcester Venous Thromboembolism Study. Thromb Haemost. 2009 May; 101(5):878-85.
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51. Rao RV, Goodman SG, Yan RT, Spencer FA, Fox KA, DeYoung JP, Rose B, Grondin FR, Gallo R, Gore JM, Yan AT. Temporal trends and patterns of early clopidogrel use across the spectrum of acute coronary syndromes. Am Heart J. 2009 Apr; 157(4):642-50.e1.
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52. Floyd KC, Yarzebski J, Spencer FA, Lessard D, Dalen JE, Alpert JS, Gore JM, Goldberg RJ. A 30-year perspective (1975-2005) into the changing landscape of patients hospitalized with initial acute myocardial infarction: Worcester Heart Attack Study. Circ Cardiovasc Qual Outcomes. 2009 Mar; 2(2):88-95.
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53. Goldberg RJ, Spencer FA, Gore JM, Lessard D, Yarzebski J. Thirty-year trends (1975 to 2005) in the magnitude of, management of, and hospital death rates associated with cardiogenic shock in patients with acute myocardial infarction: a population-based perspective. Circulation. 2009 Mar 10; 119(9):1211-9.
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54. Goldberg RJ, Spencer FA, Fox KA, Brieger D, Steg PG, Gurfinkel E, Dedrick R, Gore JM. Prehospital Delay in Patients With Acute Coronary Syndromes (from the Global Registry of Acute Coronary Events [GRACE]). Am J Cardiol. 2009 Mar 1; 103(5):598-603.
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55. Wasser J, Goldberg RJ, Spencer FA, Yarzebski J, Gore JM. Multidecade-long trends (1986-2005) in the utilization of coronary reperfusion and revascularization treatment strategies in patients hospitalized with acute myocardial infarction: a community-wide perspective. Coron Artery Dis. 2009 Jan; 20(1):71-80.
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56. Gore JM, Spencer FA, Gurfinkel EP, López-Sendón J, Steg PG, Granger CB, FitzGerald G, Agnelli G. Thrombocytopenia in patients with an acute coronary syndrome (from the Global Registry of Acute Coronary Events [GRACE]). Am J Cardiol. 2009 Jan 15; 103(2):175-80.
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57. Spencer FA, Gore JM, Lessard D, Emery C, Pacifico L, Reed G, Gurwitz JH, Goldberg RJ. Venous thromboembolism in the elderly. A community-based perspective. Thromb Haemost. 2008 Nov; 100(5):780-8.
  View in: PubMed
 
58. Saczynski JS, Yarzebski J, Lessard D, Spencer FA, Gurwitz JH, Gore JM, Goldberg RJ. Trends in prehospital delay in patients with acute myocardial infarction (from the Worcester Heart Attack Study). Am J Cardiol. 2008 Dec 15; 102(12):1589-94.
  View in: PubMed
 
59. Saczynski JS, Spencer FA, Gore JM, Gurwitz JH, Yarzebski J, Lessard D, Goldberg RJ. Twenty-year trends in the incidence of stroke complicating acute myocardial infarction: Worcester Heart Attack Study. Arch Intern Med. 2008 Oct 27; 168(19):2104-10.
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60. Goldberg RJ, Yarzebski J, Spencer FA, Zevallos JC, Lessard D, Gore JM. Thirty-year trends (1975-2005) in the magnitude, patient characteristics, and hospital outcomes of patients with acute myocardial infarction complicated by ventricular fibrillation. Am J Cardiol. 2008 Dec 15; 102(12):1595-601.
  View in: PubMed
 
61. Spencer FA, Ginsberg JS, Chong A, Alter DA. The relationship between unprovoked venous thromboembolism, age, and acute myocardial infarction. J Thromb Haemost. 2008 Sep; 6(9):1507-13.
  View in: PubMed
 
62. Nguyen HL, Lessard D, Spencer FA, Yarzebski J, Zevallos JC, Gore JM, Goldberg RJ. Thirty-year trends (1975-2005) in the magnitude and hospital death rates associated with complete heart block in patients with acute myocardial infarction: a population-based perspective. Am Heart J. 2008 Aug; 156(2):227-33.
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63. Goldberg RJ, Goldberg JH, Pruell S, Yarzebski J, Lessard D, Spencer FA, Gore JM. Delays in seeking medical care in hospitalized patients with decompensated heart failure. Am J Med. 2008 Mar; 121(3):212-8.
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64. Spencer FA, Gore JM, Lessard D, Douketis JD, Emery C, Goldberg RJ. Patient outcomes after deep vein thrombosis and pulmonary embolism: the Worcester Venous Thromboembolism Study. Arch Intern Med. 2008 Feb 25; 168(4):425-30.
  View in: PubMed
 
65. Goldberg RJ, Ismailov RM, Patlolla V, Lessard D, Spencer FA. Therapies for acute heart failure in patients with reduced kidney function: a community-based perspective. Am J Kidney Dis. 2008 Apr; 51(4):594-602.
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66. Yarzebski J, Granillo E, Spencer FA, Lessard D, Gurwitz JH, Gore JM, Goldberg RJ. Changing trends (1986-2003) in the use of lipid lowering medication in patients hospitalized with acute myocardial infarction: a community-based perspective. Int J Cardiol. 2009 Feb 6; 132(1):66-74.
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67. Goldberg RJ, Spencer FA, Okolo J, Lessard D, Yarzebski J, Gore JM. Long-term trends (1986-2003) in the use of coronary reperfusion strategies in patients hospitalized with acute myocardial infarction in central Massachusetts. Int J Cardiol. 2008 Dec 17; 131(1):83-9.
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68. Spencer FA, Moscucci M, Granger CB, Gore JM, Goldberg RJ, Steg PG, Goodman SG, Budaj A, FitzGerald G, Fox KA. Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction? Circulation. 2007 Dec 11; 116(24):2793-801.
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69. Ismailov RM, Goldberg RJ, Lessard D, Spencer FA. Decompensated heart failure in the setting of kidney dysfunction: a community-wide perspective. Nephron Clin Pract. 2007; 107(4):c147-55.
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70. Mazor KM, Baril J, Dugan E, Spencer F, Burgwinkle P, Gurwitz JH. Patient education about anticoagulant medication: is narrative evidence or statistical evidence more effective? Patient Educ Couns. 2007 Dec; 69(1-3):145-57.
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71. Goldberg RJ, Spencer FA, Steg PG, Flather M, Montalescot G, Gurfinkel EP, Kennelly BM, Goodman SG, Dedrick R, Gore JM. Increasing use of single and combination medical therapy in patients hospitalized for acute myocardial infarction in the 21st century: a multinational perspective. Arch Intern Med. 2007 Sep 10; 167(16):1766-73.
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72. Spencer FA. Review: Flight times >8 hours and presence of risk factors for VTE increases travel related VTE. Evid Based Med. 2007 Aug; 12(4):105.
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73. Spencer FA, Emery C, Lessard D, Goldberg RJ. Upper extremity deep vein thrombosis: a community-based perspective. Am J Med. 2007 Aug; 120(8):678-84.
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74. Spencer FA, Lessard D, Emery C, Reed G, Goldberg RJ. Venous thromboembolism in the outpatient setting. Arch Intern Med. 2007 Jul 23; 167(14):1471-5.
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75. Spencer FA, Steg PG. Major bleeding after PCI. Where is our crystal ball? Eur Heart J. 2007 Aug; 28(16):1917-9.
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76. Spencer FA. Review: Flight times greater than 8 hours and the presence of risk factors for VTE increase travel-related VTE. ACP J Club. 2007 Jul-Aug; 147(1):7.
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77. Spencer FA, Goldberg RJ, Gore JM, Fox KA, Avezum A, Agnelli G, Kritharides L, Anderson FA, Goodman SG, FitzGerald G, Allegrone J, Brieger D. Comparison of utilization of statin therapy at hospital discharge and six-month outcomes in patients with an acute coronary syndrome and serum low-density lipoprotein>or=100 mg/dl versus<100 mg/dl. Am J Cardiol. 2007 Sep 15; 100(6):913-8.
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78. Tapson VF, Decousus H, Pini M, Chong BH, Froehlich JB, Monreal M, Spyropoulos AC, Merli GJ, Zotz RB, Bergmann JF, Pavanello R, Turpie AG, Nakamura M, Piovella F, Kakkar AK, Spencer FA, Fitzgerald G, Anderson FA. Venous thromboembolism prophylaxis in acutely ill hospitalized medical patients: findings from the International Medical Prevention Registry on Venous Thromboembolism. Chest. 2007 Sep; 132(3):936-45.
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79. Goldberg RJ, Spencer FA, Okolo J, Lessard D, Yarzebski J, Gore JM. Long-term trends in the use of coronary reperfusion strategies in acute myocardial infarction: a community-wide perspective. J Thromb Thrombolysis. 2007 Jun; 23(3):163-71.
  View in: PubMed
 
80. Hahn J, Lessard D, Yarzebski J, Goldberg J, Pruell S, Spencer FA, Gore JM, Goldberg RJ. A community-wide perspective into changing trends in the utilization of diagnostic and interventional procedures in patients hospitalized with acute myocardial infarction. Am Heart J. 2007 Apr; 153(4):594-605.
  View in: PubMed
 
81. Goldberg RJ, Ciampa J, Lessard D, Meyer TE, Spencer FA. Long-term survival after heart failure: a contemporary population-based perspective. Arch Intern Med. 2007 Mar 12; 167(5):490-6.
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82. Gore JM, Spencer FA, Goldberg RJ, Kennelly BM, Fox KA, Allegrone J, Eagle KA, Anderson FA, Steg PG. Use of heparins in Non-ST-elevation acute coronary syndromes. Am J Med. 2007 Jan; 120(1):63-71.
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83. Goldberg RJ, Spencer FA, Farmer C, Lessard D, Pezzella SM, Meyer TE. Use of disease-modifying therapies in patients hospitalized with heart failure: a population-based perspective. Am J Med. 2007 Jan; 120(1):98.e1-8.
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84. Spencer FA, Lessard D, Doubeni C, Yarzebski J, Gore JM, Goldberg RJ. Treatment practices and outcomes of patients with established peripheral arterial disease hospitalized with acute myocardial infarction in a community setting. Am Heart J. 2007 Jan; 153(1):140-6.
  View in: PubMed
 
85. Spencer FA, Emery C, Lessard D, Anderson F, Emani S, Aragam J, Becker RC, Goldberg RJ. The Worcester Venous Thromboembolism study: a population-based study of the clinical epidemiology of venous thromboembolism. J Gen Intern Med. 2006 Jul; 21(7):722-7.
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86. Doubeni C, Bigelow C, Lessard D, Spencer F, Yarzebski J, Gore J, Gurwitz J, Goldberg R. Trends and outcomes associated with angiotensin-converting enzyme inhibitors. Am J Med. 2006 Jul; 119(7):616.e9-16.
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87. Goldberg RJ, Cui J, Olendzki B, Spencer F, Yarzebski J, Lessard D, Gore J. Excess body weight, clinical profile, management practices, and hospital prognosis in men and women after acute myocardial infarction. Am Heart J. 2006 Jun; 151(6):1297-304.
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88. Goldberg RJ, Farmer C, Spencer FA, Pezzella S, Meyer TE. Use of nonpharmacologic treatment approaches in patients with heart failure. Int J Cardiol. 2006 Jun 28; 110(3):348-53.
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89. Botkin NF, Spencer FA, Goldberg RJ, Lessard D, Yarzebski J, Gore JM. Changing trends in the long-term prognosis of patients with acute myocardial infarction: a population-based perspective. Am Heart J. 2006 Jan; 151(1):199-205.
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90. Lim MJ, Eagle KA, Gore JM, Anderson FA, Dabbous OH, Mehta RH, Granger CB, Fox KA, Spencer FA, Goldberg RJ. Treating patients with acute coronary syndromes with aggressive antiplatelet therapy (from the Global Registry of Acute Coronary Events). Am J Cardiol. 2005 Oct 1; 96(7):917-21.
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91. Spencer FA, Frederick PD, Goldberg RJ, Gore JM, Tiefenbrunn AJ. Use of combination evidence-based medical therapy prior to acute myocardial infarction (from the National Registry of Myocardial Infarction-4). Am J Cardiol. 2005 Oct 1; 96(7):922-6.
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92. Spencer FA, Lessard D, Yarzebski J, Gore JM, Goldberg RJ. Decade-long changes in the use of combination evidence-based medical therapy at discharge for patients surviving acute myocardial infarction. Am Heart J. 2005 Oct; 150(4):838-44.
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93. Fonarow GC, Wright RS, Spencer FA, Fredrick PD, Dong W, Every N, French WJ. Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality. Am J Cardiol. 2005 Sep 1; 96(5):611-6.
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94. Spencer FA, Meyer T. Heart failure and shock complicating acute coronary syndromes. Curr Cardiol Rep. 2005 Jul; 7(4):276-82.
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95. Goldberg RJ, Spencer FA, Farmer C, Meyer TE, Pezzella S. Incidence and hospital death rates associated with heart failure: a community-wide perspective. Am J Med. 2005 Jul; 118(7):728-34.
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96. Mohapatra R, Tran M, Gore JM, Spencer FA. A review of the oral direct thrombin inhibitor ximelagatran: not yet the end of the warfarin era... Am Heart J. 2005 Jul; 150(1):19-26.
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97. Budaj A, Flasinska K, Gore JM, Anderson FA, Dabbous OH, Spencer FA, Goldberg RJ, Fox KA. Magnitude of and risk factors for in-hospital and postdischarge stroke in patients with acute coronary syndromes: findings from a Global Registry of Acute Coronary Events. Circulation. 2005 Jun 21; 111(24):3242-7.
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98. Goldberg RJ, Glatfelter K, Burbank-Schmidt E, Farmer C, Spencer FA, Meyer T. Trends in mortality attributed to heart failure in Worcester, Massachusetts, 1992 to 2001. Am J Cardiol. 2005 Jun 1; 95(11):1324-8.
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99. Pretorius PH, King MA, Gifford HC, Dahlberg ST, Spencer F, Simon E, Rashkin J, Botkin N, Berndt W, Narayanan MV, Leppo JA. Myocardial perfusion SPECT reconstruction: receiver operating characteristic comparison of CAD detection accuracy of filtered backprojection reconstruction with all of the clinical imaging information available to readers and solely stress slices iteratively reconstructed with combined compensation. J Nucl Cardiol. 2005 May-Jun; 12(3):284-93.
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100. Spencer FA, Goldberg RJ. Asymptomatic thrombophilia--a family affair. J Thromb Haemost. 2005 Mar; 3(3):457-8.
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101. Lim MJ, Spencer FA, Gore JM, Dabbous OH, Agnelli G, Kline-Rogers EM, Dibenedetto D, Eagle KA, Mehta RH. Impact of combined pharmacologic treatment with clopidogrel and a statin on outcomes of patients with non-ST-segment elevation acute coronary syndromes: perspectives from a large multinational registry. Eur Heart J. 2005 Jun; 26(11):1063-9.
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102. Goldberg RJ, Spencer F, Lessard D, Yarzebski J, Lareau C, Gore JM. Occurrence of acute myocardial infarction in Worcester, Massachusetts, before, during, and after the terrorists attacks in New York City and Washington, DC, on 11 September 2001. Am J Cardiol. 2005 Jan 15; 95(2):258-60.
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103. Tran M, Spencer FA. Thromboepidemiology: identifying patients with heritable risk for thrombin-mediated thromboembolic events. Am Heart J. 2005 Jan; 149(1 Suppl):S9-18.
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104. Avezum A, Makdisse M, Spencer F, Gore JM, Fox KA, Montalescot G, Eagle KA, White K, Mehta RH, Knobel E, Collet JP. Impact of age on management and outcome of acute coronary syndrome: observations from the Global Registry of Acute Coronary Events (GRACE). Am Heart J. 2005 Jan; 149(1):67-73.
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105. Goldberg RJ, Spencer FA, Yarzebski J, Lessard D, Gore JM, Alpert JS, Dalen JE. A 25-year perspective into the changing landscape of patients hospitalized with acute myocardial infarction (the Worcester Heart Attack Study). Am J Cardiol. 2004 Dec 1; 94(11):1373-8.
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106. Becker RC, Alexander J, Li YF, Bovill E, Spencer FA, Robertson TL, Kunitada S, Dyke CK, Harrington RA. Combined coagulation phase-directed factor Xa inhibition with heparin compounds and DX-9065a - a direct and selective antagonist. Thromb Haemost. 2004 Dec; 92(6):1229-31.
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107. Becker RC, Alexander JH, Li Y, Robertson T, Kunitada S, Spencer FA, Yang H, Harrington RA. Vascular endothelial tissue factor pathway inhibitor kinetics in culture following exposure to DX-9065a--a selective and direct factor Xa inhibitor. J Thromb Thrombolysis. 2004 Dec; 18(3):193-7.
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108. Spencer FA, Fonarow GC, Frederick PD, Wright RS, Every N, Goldberg RJ, Gore JM, Dong W, Becker RC, French W. Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction. Arch Intern Med. 2004 Oct 25; 164(19):2162-8.
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109. Li Y, Becker KC, Slatkin D, Spencer F, Becker RC. The effect of temperature variation in vitro on platelet-leukocyte interactions and individual prothrombotic potential. J Thromb Thrombolysis. 2004 Aug; 18(1):19-23.
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110. Franklin K, Goldberg RJ, Spencer F, Klein W, Budaj A, Brieger D, Marre M, Steg PG, Gowda N, Gore JM. Implications of diabetes in patients with acute coronary syndromes. The Global Registry of Acute Coronary Events. Arch Intern Med. 2004 Jul 12; 164(13):1457-63.
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111. Spencer FA, Allegrone J, Goldberg RJ, Gore JM, Fox KA, Granger CB, Mehta RH, Brieger D. Association of statin therapy with outcomes of acute coronary syndromes: the GRACE study. Ann Intern Med. 2004 Jun 1; 140(11):857-66.
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112. Spencer FA, Lessard D, Gore JM, Yarzebski J, Goldberg RJ. Declining length of hospital stay for acute myocardial infarction and postdischarge outcomes: a community-wide perspective. Arch Intern Med. 2004 Apr 12; 164(7):733-40.
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113. Spencer FA, Becker RC. When guidelines collide... Am Heart J. 2004 Mar; 147(3):395-7.
  View in: PubMed
 
114. Mehta RH, Sadiq I, Goldberg RJ, Gore JM, Avezum A, Spencer F, Kline-Rogers E, Allegrone J, Pieper K, Fox KA, Eagle KA. Effectiveness of primary percutaneous coronary intervention compared with that of thrombolytic therapy in elderly patients with acute myocardial infarction. Am Heart J. 2004 Feb; 147(2):253-9.
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115. Narayanan MV, King MA, Pretorius PH, Dahlberg ST, Spencer F, Simon E, Ewald E, Healy E, MacNaught K, Leppo JA. Human-observer receiver-operating-characteristic evaluation of attenuation, scatter, and resolution compensation strategies for (99m)Tc myocardial perfusion imaging. J Nucl Med. 2003 Nov; 44(11):1725-34.
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116. Montalescot G, Van de Werf F, Gulba DC, Avezum A, Brieger D, Kennelly BM, Mazurek T, Spencer F, White K, Gore JM. Stenting and glycoprotein IIb/IIIa inhibition in patients with acute myocardial infarction undergoing percutaneous coronary intervention: findings from the global registry of acute coronary events (GRACE). Catheter Cardiovasc Interv. 2003 Nov; 60(3):360-7.
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117. Silvet H, Spencer F, Yarzebski J, Lessard D, Gore JM, Goldberg RJ. Communitywide trends in the use and outcomes associated with beta-blockers in patients with acute myocardial infarction: the Worcester Heart Attack Study. Arch Intern Med. 2003 Oct 13; 163(18):2175-83.
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118. Spencer FA, Gore JM, Yarzebski J, Lessard D, Jackson EA, Goldberg RJ. Trends (1986 to 1999) in the incidence and outcomes of in-hospital stroke complicating acute myocardial infarction (The Worcester Heart Attack Study). Am J Cardiol. 2003 Aug 15; 92(4):383-8.
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119. Fox KA, Goodman SG, Anderson FA, Granger CB, Moscucci M, Flather MD, Spencer F, Budaj A, Dabbous OH, Gore JM. From guidelines to clinical practice: the impact of hospital and geographical characteristics on temporal trends in the management of acute coronary syndromes. The Global Registry of Acute Coronary Events (GRACE). Eur Heart J. 2003 Aug; 24(15):1414-24.
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120. Spencer FA, Becker RC. Circadian variations in acute myocardial infarction: patients or health care delivery? J Am Coll Cardiol. 2003 Jun 18; 41(12):2143-6.
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121. Anderson FA, Spencer FA. Risk factors for venous thromboembolism. Circulation. 2003 Jun 17; 107(23 Suppl 1):I9-16.
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122. Spencer FA, Jabbour S, Lessard D, Yarzebski J, Ravid S, Zaleskas V, Hyder M, Gore JM, Goldberg RJ. Two-decade-long trends (1975-1997) in the incidence, hospitalization, and long-term death rates associated with complete heart block complicating acute myocardial infarction: a community-wide perspective. Am Heart J. 2003 Mar; 145(3):500-7.
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123. Li Y, Spencer FA, Becker RC. Plasmin-mediated proteolysis of vascular endothelial cell heparin releasable tissue factor pathway inhibitor. J Thromb Thrombolysis. 2003 Feb; 15(1):19-23.
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124. Spencer FA, Santopinto JJ, Gore JM, Goldberg RJ, Fox KA, Moscucci M, White K, Gurfinkel EP. Impact of aspirin on presentation and hospital outcomes in patients with acute coronary syndromes (The Global Registry of Acute Coronary Events [GRACE]). Am J Cardiol. 2002 Nov 15; 90(10):1056-61.
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125. Li Y, Rodriquez M, Spencer FA, Becker RC. Comparative effects of unfractionated heparin and low molecular weight heparin on vascular endothelial cell tissue factor pathway inhibitor release: a model for assessing intrinsic thromboresistance. J Thromb Thrombolysis. 2002 Oct; 14(2):123-9.
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126. Jackson EA, Sivasubramian R, Spencer FA, Yarzebski J, Lessard D, Gore JM, Goldberg RJ. Changes over time in the use of aspirin in patients hospitalized with acute myocardial infarction (1975 to 1997): a population-based perspective. Am Heart J. 2002 Aug; 144(2):259-68.
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127. Spencer FA, Meyer TE, Gore JM, Goldberg RJ. Heterogeneity in the management and outcomes of patients with acute myocardial infarction complicated by heart failure: the National Registry of Myocardial Infarction. Circulation. 2002 Jun 4; 105(22):2605-10.
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128. Becker RC, Spencer FA, Gibson M, Rush JE, Sanderink G, Murphy SA, Ball SP, Antman EM. Influence of patient characteristics and renal function on factor Xa inhibition pharmacokinetics and pharmacodynamics after enoxaparin administration in non-ST-segment elevation acute coronary syndromes. Am Heart J. 2002 May; 143(5):753-9.
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129. Yarzebski J, Bujor CF, Goldberg RJ, Spencer F, Lessard D, Gore JM. A community-wide survey of physician practices and attitudes toward cholesterol management in patients with recent acute myocardial infarction. Arch Intern Med. 2002 Apr 8; 162(7):797-804.
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130. Li YF, Spencer FA, Becker RC. Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa receptor-directed platelet inhibition. Am Heart J. 2002 Apr; 143(4):725-32.
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131. Le Nguyen MT, Spencer FA. Low molecular weight heparin and unfractionated heparin in the early pharmacologic management of acute coronary syndromes: a meta-analysis of randomized clinical trials. J Thromb Thrombolysis. 2001 Dec; 12(3):289-95.
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132. Spencer FA, Salami B, Yarzebski J, Lessard D, Gore JM, Goldberg RJ. Temporal trends and associated factors of inpatient cardiac rehabilitation in patients with acute myocardial infarction: a community-wide perspective. J Cardiopulm Rehabil. 2001 Nov-Dec; 21(6):377-84.
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133. Spencer F, Scleparis G, Goldberg RJ, Yarzebski J, Lessard D, Gore JM. Decade-long trends (1986 to 1997) in the medical treatment of patients with acute myocardial infarction: A community-wide perspective. Am Heart J. 2001 Oct; 142(4):594-603.
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134. Li YF, Spencer FA, Becker RC. Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa (alphaIIb/beta3) receptor-directed platelet inhibition. Am Heart J. 2001 Aug; 142(2):204-10.
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135. Spencer FA, Goldberg RJ, Frederick PD, Malmgren J, Becker RC, Gore JM. Age and the utilization of cardiac catheterization following uncomplicated first acute myocardial infarction treated with thrombolytic therapy (The Second National Registry of Myocardial Infarction [NRMI-2]). Am J Cardiol. 2001 Jul 15; 88(2):107-11.
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136. Yarzebski J, Spencer F, Goldberg RJ, Lessard D, Gore JM. Temporal trends (1986-1997) in cholesterol level assessment and management practices in patients with acute myocardial infarction: a population-based perspective. Arch Intern Med. 2001 Jun 25; 161(12):1521-8.
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137. Becker RC, Burns M, Every N, Maynard C, Frederick P, Spencer FA, Gore JM, Lambrew C. Early clinical outcomes and routine management of patients with non-ST-segment elevation myocardial infarction: a nationwide perspective. Arch Intern Med. 2001 Feb 26; 161(4):601-7.
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138. Spencer FA. Heparin-induced thrombocytopenia: patient profiles and clinical manifestations. J Thromb Thrombolysis. 2000 Nov; 10 Suppl 1:21-25.
  View in: PubMed
 
139. Spencer FC. Human error in hospitals and industrial accidents: current concepts. J Am Coll Surg. 2000 Oct; 191(4):410-8.
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140. Spencer FA, Becker RC. Novel inhibitors of factor X for use in cardiovascular diseases. Curr Cardiol Rep. 2000 Sep; 2(5):395-404.
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141. Li Y, Spencer FA, Ball S, Becker RC. Inhibition of platelet-dependent prothrombinase activity and thrombin generation by glycoprotein IIb/IIIa receptor-directed antagonists: potential contributing mechanism of benefit in acute coronary syndromes. J Thromb Thrombolysis. 2000 Aug; 10(1):69-76.
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142. Spencer FA, Ball SP, Zhang Q, Liu L, Benoit S, Becker RC. Enoxaparin, a low molecular weight heparin, inhibits platelet-dependent prothrombinase assembly and activity by factor-Xa neutralization. J Thromb Thrombolysis. 2000 Apr; 9(3):223-8.
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143. Spencer FA. Key references: Protein C, protein S, and antithrombin deficiencies. J Thromb Thrombolysis. 2000 Jan; 9(1):127.
  View in: PubMed
 
144. Spencer FA. Key references: Antiphospholipid antibody syndrome. J Thromb Thrombolysis. 2000 Jan; 9(1):129-30.
  View in: PubMed
 
145. Spencer FA, Meyer TE, Goldberg RJ, Yarzebski J, Hatton M, Lessard D, Gore JM. Twenty year trends (1975-1995) in the incidence, in-hospital and long-term death rates associated with heart failure complicating acute myocardial infarction: a community-wide perspective. J Am Coll Cardiol. 1999 Nov 1; 34(5):1378-87.
  View in: PubMed
 
146. Becker RC, Spencer FA, Li Y, Ball SP, Ma Y, Hurley T, Hebert J. Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary syndromes: potential mechanisms for heightened prothrombotic potential. J Am Coll Cardiol. 1999 Oct; 34(4):1020-7.
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147. Spencer FA, Becker RC. Diagnosis and management of inherited and acquired thrombophilias. J Thromb Thrombolysis. 1999 Apr; 7(2):91-104.
  View in: PubMed
 
148. Becker RC, Hochman JS, Cannon CP, Spencer FA, Ball SP, Rizzo MJ, Antman EM. Fatal cardiac rupture among patients treated with thrombolytic agents and adjunctive thrombin antagonists: observations from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction 9 Study. J Am Coll Cardiol. 1999 Feb; 33(2):479-87.
  View in: PubMed
 
149. Becker RC, Ball SP, Eisenberg P, Borzak S, Held AC, Spencer F, Voyce SJ, Jesse R, Hendel R, Ma Y, Hurley T, Hebert J. A randomized, multicenter trial of weight-adjusted intravenous heparin dose titration and point-of-care coagulation monitoring in hospitalized patients with active thromboembolic disease. Antithrombotic Therapy Consortium Investigators. Am Heart J. 1999 Jan; 137(1):59-71.
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150. Grossi EA, Galloway AC, Zakow PK, Miller JS, Buttenheim PM, Baumann FG, Culliford AT, Spencer FC, Colvin SB. Choice of mitral prosthesis in the elderly. An analysis of actual outcome. Circulation. 1998 Nov 10; 98(19 Suppl):II116-9.
  View in: PubMed
 
151. Spencer FA, Goldberg RJ, Becker RC, Gore JM. Seasonal distribution of acute myocardial infarction in the second National Registry of Myocardial Infarction. J Am Coll Cardiol. 1998 May; 31(6):1226-33.
  View in: PubMed
 
152. Becker RC, Burns M, Gore JM, Spencer FA, Ball SP, French W, Lambrew C, Bowlby L, Hilbe J, Rogers WJ. Early assessment and in-hospital management of patients with acute myocardial infarction at increased risk for adverse outcomes: a nationwide perspective of current clinical practice. The National Registry of Myocardial Infarction (NRMI-2) Participants. Am Heart J. 1998 May; 135(5 Pt 1):786-96.
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153. Galloway AC, Schwartz DS, Culliford AT, Ribakove GH, Grossi EA, Esposito RA, Baumann FG, Delianides J, Spencer FC, Colvin SB. Selective approach to descending thoracic aortic aneurysm repair: a ten-year experience. Ann Thorac Surg. 1996 Oct; 62(4):1152-7.
  View in: PubMed
 
154. Giangola G, Migaly J, Riles TS, Lamparello PJ, Adelman MA, Grossi E, Colvin SB, Pasternak PF, Galloway A, Culliford AT, Esposito R, Ribacove G, Crawford BK, Glassman L, Baumann FG, Spencer FC. Perioperative morbidity and mortality in combined vs. staged approaches to carotid and coronary revascularization. Ann Vasc Surg. 1996 Mar; 10(2):138-42.
  View in: PubMed
 
155. Grossi EA, Chinitz LA, Galloway AC, Delianides J, Schwartz DS, McLoughlin DE, Keller N, Kronzon I, Spencer FC, Colvin SB. Endoventricular remodeling of left ventricular aneurysm. Functional, clinical, and electrophysiological results. Circulation. 1995 Nov 1; 92(9 Suppl):II98-100.
  View in: PubMed
 
156. Grossi EA, Galloway AC, LeBoutillier M, Steinberg B, Baumann FG, Delianides J, Spencer FC, Colvin SB. Anterior leaflet procedures during mitral valve repair do not adversely influence long-term outcome. J Am Coll Cardiol. 1995 Jan; 25(1):134-6.
  View in: PubMed
 
157. Grossi EA, Steinberg BM, LeBoutillier M, Ribacove G, Spencer FC, Galloway AC, Colvin SB. Decreasing incidence of systolic anterior motion after mitral valve reconstruction. Circulation. 1994 Nov; 90(5 Pt 2):II195-7.
  View in: PubMed
 
158. Grossi EA, Galloway AC, Steinberg BM, LeBoutillier M, Delianides J, Baumann FG, Spencer FC, Colvin SB. Severe calcification does not affect long-term outcome of mitral valve repair. Ann Thorac Surg. 1994 Sep; 58(3):685-7; discussion 688.
  View in: PubMed
 
159. Katz ES, Tunick PA, Rusinek H, Ribakove G, Spencer FC, Kronzon I. Protruding aortic atheromas predict stroke in elderly patients undergoing cardiopulmonary bypass: experience with intraoperative transesophageal echocardiography. J Am Coll Cardiol. 1992 Jul; 20(1):70-7.
  View in: PubMed
 
160. Galloway AC, Grossi EA, Baumann FG, LaMendola CL, Crooke GA, Harris LJ, Colvin SB, Spencer FC. Multiple valve operation for advanced valvular heart disease: results and risk factors in 513 patients. J Am Coll Cardiol. 1992 Mar 15; 19(4):725-32.
  View in: PubMed
 
161. Grossi EA, Esposito R, Harris LJ, Crooke GA, Galloway AC, Colvin SB, Culliford AT, Baumann FG, Yao K, Spencer FC. Sternal wound infections and use of internal mammary artery grafts. J Thorac Cardiovasc Surg. 1991 Sep; 102(3):342-6; discussion 346-7.
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162. Culliford AT, Galloway AC, Colvin SB, Grossi EA, Baumann FG, Esposito R, Ribakove GH, Spencer FC. Aortic valve replacement for aortic stenosis in persons aged 80 years and over. Am J Cardiol. 1991 Jun 1; 67(15):1256-60.
  View in: PubMed
 
163. Spencer FC. A critique of emergency and urgent operations for complications of coronary artery disease. Circulation. 1989 Jun; 79(6 Pt 2):I160-2.
  View in: PubMed
 
164. Galloway AC, Colvin SB, Baumann FG, Grossi EA, Ribakove GH, Harty S, Spencer FC. A comparison of mitral valve reconstruction with mitral valve replacement: intermediate-term results. Ann Thorac Surg. 1989 May; 47(5):655-62.
  View in: PubMed
 
165. Axelrod HI, Murphy MS, Galloway AC, Baumann FG, Laschinger JC, Colvin SB, Spencer FC. Percutaneous cardiopulmonary bypass limits myocardial injury from ischemic fibrillation and reperfusion. Circulation. 1988 Nov; 78(5 Pt 2):III148-52.
  View in: PubMed
 
166. Galloway AC, Colvin SB, Baumann FG, Esposito R, Vohra R, Harty S, Freeberg R, Kronzon I, Spencer FC. Long-term results of mitral valve reconstruction with Carpentier techniques in 148 patients with mitral insufficiency. Circulation. 1988 Sep; 78(3 Pt 2):I97-105.
  View in: PubMed
 
167. Axelrod HI, Galloway AC, Murphy MS, Laschinger JC, Grossi EA, Baumann FG, Colvin SB, Hunter CE, Glassman E, Spencer FC. A comparison of methods for limiting myocardial infarct expansion during acute reperfusion--primary role of unloading. Circulation. 1987 Nov; 76(5 Pt 2):V28-32.
  View in: PubMed
 
168. Vlay SC, Spencer FC. Prophylactic replacement of a Starr-Edwards model 1000 aortic valve prosthesis in place for 20 years. Am J Cardiol. 1984 Mar 15; 53(7):969.
  View in: PubMed
 
169. Weitzman LB, Tinker WP, Kronzon I, Cohen ML, Glassman E, Spencer FC. The incidence and natural history of pericardial effusion after cardiac surgery--an echocardiographic study. Circulation. 1984 Mar; 69(3):506-11.
  View in: PubMed
 
170. Rose DM, Ranson JH, Cunningham JN, Spencer FC. Patterns of severe pancreatic injury following cardiopulmonary bypass. Ann Surg. 1984 Feb; 199(2):168-72.
  View in: PubMed
 
171. Catinella FP, Cunningham JN, Glassman E, Laschinger JC, Baumann FG, Spencer FC. Left atrium-to-femoral artery bypass: effectiveness in reduction of acute experimental myocardial infarction. J Thorac Cardiovasc Surg. 1983 Dec; 86(6):887-96.
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172. Rose DM, Colvin SB, Culliford AT, Isom OW, Cunningham JN, Glassman E, Spencer FC. Late functional and hemodynamic status of surviving patients following insertion of the left heart assist device. J Thorac Cardiovasc Surg. 1983 Nov; 86(5):639-45.
  View in: PubMed
 
173. Laschinger JC, Cunningham JN, Isom OW, Nathan IM, Spencer FC. Definition of the safe lower limits of aortic resection during surgical procedures on the thoracoabdominal aorta: use of somatosensory evoked potentials. J Am Coll Cardiol. 1983 Nov; 2(5):959-65.
  View in: PubMed
 
174. Esposito RA, Culliford AT, Colvin SB, Thomas SJ, Lackner H, Spencer FC. Heparin resistance during cardiopulmonary bypass. The role of heparin pretreatment. J Thorac Cardiovasc Surg. 1983 Mar; 85(3):346-53.
  View in: PubMed
 
175. Rose DM, Colvin SB, Culliford AT, Cunningham JN, Adams PX, Glassman E, Isom OW, Spencer FC. Long-term survival with partial left heart bypass following perioperative myocardial infarction and shock. J Thorac Cardiovasc Surg. 1982 Apr; 83(4):483-92.
  View in: PubMed
 
176. Gross RI, Cunningham JN, Snively SL, Catinella FP, Nathan IM, Adams PX, Spencer FC. Long-term results of open radical mitral commissurotomy: ten year follow-up study of 202 patients. Am J Cardiol. 1981 Apr; 47(4):821-5.
  View in: PubMed
 
177. Culliford AT, Gitel SN, Starr N, Thomas ST, Baumann FG, Wessler S, Spencer FC. Lack of correlation between activated clotting time and plasma heparin during cardiopulmonary bypass. Ann Surg. 1981 Jan; 193(1):105-11.
  View in: PubMed
 
178. Griffiths SP, Zazula BM, Courtney D, Spencer FC, Malm JR. Trends in cardiovascular surgery (1961 to 1977): review of the New York City and State experience. Am J Cardiol. 1979 Sep; 44(3):555-62.
  View in: PubMed
 
179. Winer HE, Glassman E, Spencer FC. Mechanism of relief of angina after coronary bypass surgery: an angiographic study. Am J Cardiol. 1979 Aug; 44(2):202-8.
  View in: PubMed
 
180. Culliford AT, Girdwood RW, Isom OW, Krauss KR, Spencer FC. Angina following myocardial revascularization. Does time of recurrence predict etiology and influence results of operation? J Thorac Cardiovasc Surg. 1979 Jun; 77(6):889-95.
  View in: PubMed
 
181. Culliford AT, Lipton M, Isom OW, Cunningham J, Boyd AD, Adams P, Reed G, Spencer FC. Surgery for chronic constrictive pericarditis. Does surgical approach and degree of pericardial resection significantly influence outcome? N Y State J Med. 1978 Sep; 78(11):1719-21.
  View in: PubMed
 
182. Spencer FC. A plea for early, open mitral commissurotomy. Am Heart J. 1978 May; 95(5):668-70.
  View in: PubMed
 
183. Adams PX, Cunningham JN, Trehan NK, Brazier JR, Reed GE, Spencer FC. Clinical experience using potassium-induced cardioplegia with hypothermia in aortic valve replacement. J Thorac Cardiovasc Surg. 1978 Apr; 75(4):564-8.
  View in: PubMed
 
184. Isom OW, Spencer FC, Glassman E, Cunningham JN, Teiko P, Reed GE, Boyd AD. Does coronary bypass increase longevity? J Thorac Cardiovasc Surg. 1978 Jan; 75(1):28-37.
  View in: PubMed
 
185. Adams PX, Cunningham JN, Brazier J, Pappis M, Trehan N, Spencer FC. Technique and experience using potassium cardioplegia during myocardial revascularization for preinfarction angina. Surgery. 1978 Jan; 83(1):12-9.
  View in: PubMed
 
186. Boyd AD, Spencer FC, Isom OW, Cunningham JN, Reed GE, Acinapura AJ, Tice DA. Infective endocarditis. An analysis of 54 surgically treated patients. J Thorac Cardiovasc Surg. 1977 Jan; 73(1):23-30.
  View in: PubMed
 
187. Reed GE, Boyd AD, Spencer FC, Engelman RM, Isom OW, Cunningham JN. Operative management of tricuspid regurgitation. Circulation. 1976 Dec; 54(6 Suppl):III96-8.
  View in: PubMed
 
188. Singh A, Doyle EF, Danilowicz D, Spencer FC. Masked abnormal drainage of the inferior vena cava into the left atrium. Am J Cardiol. 1976 Aug; 38(2):261-4.
  View in: PubMed
 
189. Engelman RM, Bhat JG, Glassman E, Spencer FC, Boyd AD, Reed GE, Isom OW, Pasternack BS. The influence of diabetes and hypertension on the results of coronary revascularization. Am J Med Sci. 1976 Jan-Feb; 271(1):4-12.
  View in: PubMed
 
190. Isom OW, Spencer FC, Glassman E, Dembrow JM, Pasternack BS. Long-term survival following coronary bypass surgery in patients with significant impairment of left ventricular function. Circulation. 1975 Aug; 52(2 Suppl):I141-7.
  View in: PubMed
 
191. Rose MR, Glassman E, Spencer FC. Arrhythmias following cardiac surgery: relation to serum digoxin levels. Am Heart J. 1975 Mar; 89(3):288-94.
  View in: PubMed
 
192. Danilowicz D, Posnock E, Chase R, Spencer FC. Salmonella septicemia after open heart surgery in an asymptomatic carrier. Am J Cardiol. 1974 Dec; 34(7):864-7.
  View in: PubMed
 
193. Mullin MJ, Engelman RM, Isom OW, Boyd AD, Glassman E, Spencer FC. Experience with open mitral commissurotomy in 100 consecutive patients. Surgery. 1974 Dec; 76(6):974-82.
  View in: PubMed
 
194. Suwansirikul S, Glassman E, Raia F, Spencer FC. Late thrombosis of Starr-Edwards tricuspid ball valve prosthesis. Am J Cardiol. 1974 Nov; 34(6):737-40.
  View in: PubMed
 
195. Spencer FC, Isom OW, Glassman E, Boyd AD, Engelman RM, Reed GE, Pasternack BS, Dembrow JM. The long-term influence of coronary bypass grafts on myocardial infarction and survival. Ann Surg. 1974 Oct; 180(4):439-51.
  View in: PubMed
 
196. Boyd AD, Engelman RM, Isom OW, Reed GE, Spencer FC. Tricuspid annuloplasty. Five and one-half years' experience with 78 patients. J Thorac Cardiovasc Surg. 1974 Sep; 68(3):344-51.
  View in: PubMed
 
197. Isom OW, Dembrow JM, Glassman E, Pasternack BS, Sackler JP, Spencer FC. Factors influencing long-term survival after isolated aortic valve replacement. Circulation. 1974 Aug; 50(2 Suppl):II154-62.
  View in: PubMed
 
198. Ranson JH, Turner JW, Roses DF, Rifkind KM, Spencer FC. Respiratory complications in acute pancreatitis. Ann Surg. 1974 May; 179(5):557-66.
  View in: PubMed
 
199. Rose MR, Glassman E, Isom OW, Spencer FC. Electrocardiographic and serum enzyme changes of myocardial infarction after coronary artery bypass surgery. Am J Cardiol. 1974 Feb; 33(2):215-20.
  View in: PubMed
 
200. Isom OW, Kutin ND, Falk EA, Spencer FC. Patterns of myocardial metabolism during cardiopulmonary bypass and coronary perfusion. J Thorac Cardiovasc Surg. 1973 Nov; 66(5):705-19.
  View in: PubMed
 
201. Agarwala B, Doyle EF, Danilowicz D, Spencer FC, Mills NM. Double outlet right ventricle with pulmonic stenosis and anteriorly positioned aorta(Taussig-Bing variant). Report of a case and surgical correction. Am J Cardiol. 1973 Nov; 32(6):850-4.
  View in: PubMed
 
202. Spencer FC, Glassman E. Preinfarction angina: current therapeutic considerations. Am J Cardiol. 1973 Sep 7; 32(3):382-4.
  View in: PubMed
 
203. Isom OW, Williams CD, Falk EA, Spencer FC, Glassman E. Evaluation of anticoagulant therapy in cloth-covered prosthetic valves. Circulation. 1973 Jul; 48(1 Suppl):III48-50.
  View in: PubMed
 
204. Reed GE, Spencer FC, Boyd AD, Engelman RM, Glassman E. Late complications of intraoperative coronary artery perfusion. Circulation. 1973 Jul; 48(1 Suppl):III80-4.
  View in: PubMed
 
205. Spencer FC, Glassman E. Surgical procedures for coronary artery disease. Annu Rev Med. 1972; 23:229-44.
  View in: PubMed
 
206. Spencer FC, Green GE, Tice DA, Glassman E. Bypass grafting for occlusive disease of the coronary arteries: a report of experience with 195 patients. Ann Surg. 1971 Jun; 173(6):1029-44.
  View in: PubMed
 
207. Bryant LR, Trinkle JK, Spencer FC, Danielson GK, Shabetai R, Reeves JT. Cardiac valve replacement. Results in patients with advanced disability. JAMA. 1971 May 10; 216(6):996-1002.
  View in: PubMed
 
208. Cortes LE, Boyd AD, Spencer FC, Reed GE. The control of hemorrhage by dacron aortic prostheses. Surg Forum. 1971; 22:170-1.
  View in: PubMed
 
209. Engelman RM, Spencer FC, Reed GE, Tice DA. Cardiac tamponade following open-heart surgery. Circulation. 1970 May; 41(5 Suppl):II165-71.
  View in: PubMed
 
210. Spencer FC. Venous bypass grafts for occlusive disease of the coronary arteries. Am Heart J. 1970 Apr; 79(4):568-71.
  View in: PubMed
 
211. Spencer FC, Reed GE, Clauss RH, Tice DA, Reppert EH. Cloth-covered aortic and mitral valve prostheses. Experiences with 113 patients. J Thorac Cardiovasc Surg. 1970 Jan; 59(1):92-108.
  View in: PubMed
 
212. Spencer FC. Surgical treatment of valvular heart disease. VII. Prosthetic cardiac valves. Prognosis and management. Am Heart J. 1968 Dec; 76(6):839-44.
  View in: PubMed
 
213. Spencer FC. Surgical treatment of valvular heart disease. V. Prosthetic replacement of the mitral valve. Am Heart J. 1968 Oct; 76(4):576-80.
  View in: PubMed
 
214. Shabetai R, Adolph RJ, Spencer FC. Successful replacement of the tricuspid valve 10 years after traumatic incompetence. Am J Cardiol. 1966 Dec; 18(6):916-20.
  View in: PubMed
 
215. NOONAN JA, SPENCER FC. SINGLE CORONARY ARTERY WITH CORONARY ARTERIOVENOUS FISTUALA COMMUNICATING WITH THE RIGHT VENTRICLE. Am J Cardiol. 1965 Jun; 15:848-52.
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216. SPENCER FC, JUDE J, RIENHOFF WF, STONESIFER G. PLICATION OF THE INFERIOR VENA CAVA FOR PULMONARY EMBOLISM: LONG-TERM RESULTS IN 39 CASES. Ann Surg. 1965 May; 161:788-801.
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217. SPENCER FC, EISEMAN B, REEVES JT. THE SURGICAL TREATMENT OF HEART FAILURE AND ADAMS-STOKES ATTACKS FROM COMPLETE HEART BLOCK WITH A CARDIAC PACEMAKER. J Ky Med Assoc. 1964 May; 62:365-8.
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218. SPENCER FC, QUATTLEBAUM JK, QUATTLEBAUM JK, SHARP EH, JUDE JR. Plication of the inferior vena cava for pulmonary embolism: a report of 20 cases. Ann Surg. 1962 Jun; 155:827-37.
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219. SPENCER FC. An experimental evaluation of partitioning of the inferior vena cava to prevent pulmonary embolism. Surg Forum. 1960; 10:680-4.
  View in: PubMed
 
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Keywords   
Myocardial Infarction
Anticoagulants
Heart Failure
Venous Thrombosis
Venous Thromboembolism
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Co-Authors  
Anderson, Frederick
Goldberg, Robert
Gore, Joel
Reed, George
Yarzebski, Jorge
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Physical Neighbors  
Shih, Jeffrey
Gore, Joel
Burns, Maureen
Santolucito, Paul
Wholey, Richard

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