Susan Donohue MD
Title Assistant Professor
Institution University of Massachusetts Medical School
Department Medicine
Division Hematology Oncology
Address 299 Lincoln Street
Suite 100
Worcester MA 01605
Telephone 508-754-2273
Publications
1. Zheng J, Shan Y, Lambrecht RW, Donohue SE, Bonkovsky HL. Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin. Mol Cell Biochem. 2008 Dec; 319(1-2):153-61.
  View in: PubMed
 
2. Bonifaz V, Shan Y, Lambrecht RW, Donohue SE, Moschenross D, Bonkovsky HL. Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells. Liver Int. 2009 Mar; 29(3):366-73.
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3. Hou W, Shan Y, Zheng J, Lambrecht RW, Donohue SE, Bonkovsky HL. Zinc mesoporphyrin induces rapid and marked degradation of the transcription factor Bach1 and up-regulates HO-1. Biochim Biophys Acta. 2008 Mar; 1779(3):195-203.
  View in: PubMed
 
4. Shan Y, Lambrecht RW, Donohue SE, Bonkovsky HL. Role of Bach1 and Nrf2 in up-regulation of the heme oxygenase-1 gene by cobalt protoporphyrin. FASEB J. 2006 Dec; 20(14):2651-3.
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5. Ghaziani T, Shan Y, Lambrecht RW, Donohue SE, Pietschmann T, Bartenschlager R, Bonkovsky HL. HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells. J Hepatol. 2006 Jul; 45(1):5-12.
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6. Shan Y, Lambrecht RW, Ghaziani T, Donohue SE, Bonkovsky HL. Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS. J Biol Chem. 2004 Dec 10; 279(50):51769-74.
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7. Foley DP, Ricciardi R, Traylor AN, McLaughlin TJ, Donohue SE, Wheeler SM, Meyers WC, Quarfordt SH. Effect of hepatic artery flow on bile secretory function after cold ischemia. Am J Transplant. 2003 Feb; 3(2):148-55.
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8. Ricciardi R, Veal TM, Anwaruddin S, Wheeler SM, Foley DP, Donohue SE, Quarfordt SH, Meyers WC. Porcine hepatic phospholipid efflux during reperfusion after cold ischemia. J Surg Res. 2002 Mar; 103(1):79-88.
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9. Ricciardi R, Foley DP, Quarfordt SH, Donohue SE, Wheeler SM, Callery MP, Meyers WC. Donor hepatic function: a factor in postreperfusion syndrome. J Gastrointest Surg. 2002 Mar-Apr; 6(2):248-54.
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10. Ricciardi R, Foley DP, Quarfordt SH, Kim RD, Donohue SE, Wheeler SM, Chari RS, Callery MP, Meyers WC. Alterations in intrahepatic hemodynamics of the harvested porcine liver. J Gastrointest Surg. 2001 Sep-Oct; 5(5):490-8.
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11. Ricciardi R, Schaffer BK, Kim RD, Shah SA, Donohue SE, Wheeler SM, Quarfordt SH, Callery MP, Meyers WC, Chari RS. Protective effects of ischemic preconditioning on the cold-preserved liver are tyrosine kinase dependent. Transplantation. 2001 Aug 15; 72(3):406-12.
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12. Ricciardi R, Meyers WC, Schaffer BK, Kim RD, Shah SA, Wheeler SM, Donohue SE, Sheth KR, Callery MP, Chari RS. Protein kinase C inhibition abrogates hepatic ischemic preconditioning responses. J Surg Res. 2001 May 15; 97(2):144-9.
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13. Ricciardi R, Schaffer BK, Shah SA, Quarfordt SH, Banner BF, Wheeler SM, Donohue SE, Meyers WC, Chari RS. Bosentan, an endothelin antagonist, augments hepatic graft function by reducing graft circulatory impairment following ischemia/reperfusion injury. J Gastrointest Surg. 2001 May-Jun; 5(3):322-9.
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14. Ricciardi R, Anwaruddin S, Schaffer BK, Quarfordt SH, Donohue SE, Wheeler SM, Gallagher KA, Callery MP, Litwin DE, Meyers WC. Elevated intrahepatic pressures and decreased hepatic tissue blood flow prevent gas embolus during limited laparoscopic liver resections. Surg Endosc. 2001 Jul; 15(7):729-33.
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15. Ricciardi R, Foley DP, Quarfordt SH, Vittimberga FJ, Kim RD, Donohue SE, Wheeler SM, Anwaruddin S, Callery MP, Meyers WC. Hemodynamic and metabolic variables predict porcine ex vivo liver function. J Surg Res. 2001 Mar; 96(1):114-9.
  View in: PubMed
 
16. Ricciardi R, Foley DP, Quarfordt SH, Saavedra JE, Keefer LK, Wheeler SM, Donohue SE, Callery MP, Meyers WC. V-PYRRO/NO: an hepato-selective nitric oxide donor improves porcine liver hemodynamics and function after ischemia reperfusion. Transplantation. 2001 Jan 27; 71(2):193-8.
  View in: PubMed
 
17. Childs S, Weinstein BM, Mohideen MA, Donohue S, Bonkovsky H, Fishman MC. Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria. Curr Biol. 2000 Aug 24; 10(16):1001-4.
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18. Foley DP, Vittimberga FJ, Quarfordt SH, Donohue SE, Traylor AN, MacPhee J, McLaughlin T, Ricciardi R, Callery MP, Meyers WC. Biliary secretion of extracorporeal porcine livers with single and dual vessel perfusion. Transplantation. 1999 Aug 15; 68(3):362-8.
  View in: PubMed
 
19. Hahn M, Gildemeister OS, Krauss GL, Pepe JA, Lambrecht RW, Donohue S, Bonkovsky HL. Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria. Neurology. 1997 Jul; 49(1):97-106.
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20. Cable EE, Gildemeister OS, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Hepatic 5-aminolevulinic acid synthase mRNA stability is modulated by inhibitors of heme biosynthesis and by metalloporphyrins. Eur J Biochem. 1996 Aug 15; 240(1):112-7.
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21. Russo SM, Pepe JA, Donohue S, Cable EE, Lambrecht RW, Bonkovsky HL. Tissue distribution of zinc-mesoporphyrin in rats: relationship to inhibition of heme oxygenase. J Pharmacol Exp Ther. 1995 Feb; 272(2):766-74.
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22. Cable EE, Pepe JA, Donohue SE, Lambrecht RW, Bonkovsky HL. Effects of mifepristone (RU-486) on heme metabolism and cytochromes P-450 in cultured chick embryo liver cells, possible implications for acute porphyria. Eur J Biochem. 1994 Oct 15; 225(2):651-7.
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23. Srivastava KK, Cable EE, Donohue SE, Bonkovsky HL. Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme. Eur J Biochem. 1993 May 1; 213(3):909-17.
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24. Bonkovsky HL, Cable EE, Cable JW, Donohue SE, White EC, Greene YJ, Lambrecht RW, Srivastava KK, Arnold WN. Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh). Biochem Pharmacol. 1992 Jun 9; 43(11):2359-68.
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Litwin, Demetrius
McLaughlin, Thomas
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Physical Neighbors  
Shepro, David
Driscoll, Edward
Raffel, Glen
Li, Shaoguang
Yang, Zhongfa

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