Feng He PHD
Title Research Assistant Professor
Institution University of Massachusetts Medical School
Department Microbiology & Physiological Systems
Address University of Massachusetts Medical School
55 Lake Avenue North
Worcester MA 01655
Telephone 508-856-3361
Email
Publications
1. Landrette SF, Madera D, He F, Castilla LH. The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells. Leukemia. 2011 Apr; 25(4):655-62.
  View in: PubMed
 
2. Dong S, Jacobson A, He F. Degradation of YRA1 Pre-mRNA in the cytoplasm requires translational repression, multiple modular intronic elements, Edc3p, and Mex67p. PLoS Biol. 2010; 8(4):e1000360.
  View in: PubMed
 
3. He F, Amrani N, Johansson MJ, Jacobson A. Chapter 6. Qualitative and quantitative assessment of the activity of the yeast nonsense-mediated mRNA decay pathway. Methods Enzymol. 2008; 449:127-47.
  View in: PubMed
 
4. Johansson MJ, He F, Spatrick P, Li C, Jacobson A. Association of yeast Upf1p with direct substrates of the NMD pathway. Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52):20872-7.
  View in: PubMed
 
5. Dong S, Li C, Zenklusen D, Singer RH, Jacobson A, He F. YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA. Mol Cell. 2007 Feb 23; 25(4):559-73.
  View in: PubMed
 
6. Amrani N, Dong S, He F, Ganesan R, Ghosh S, Kervestin S, Li C, Mangus DA, Spatrick P, Jacobson A. Aberrant termination triggers nonsense-mediated mRNA decay. Biochem Soc Trans. 2006 Feb; 34(Pt 1):39-42.
  View in: PubMed
 
7. Wang S, Farfan-Arribas DJ, Shen S, Chou TH, Hirsch A, He F, Lu S. Relative contributions of codon usage, promoter efficiency and leader sequence to the antigen expression and immunogenicity of HIV-1 Env DNA vaccine. Vaccine. 2006 May 22; 24(21):4531-40.
  View in: PubMed
 
8. He F, Li X, Spatrick P, Casillo R, Dong S, Jacobson A. Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast. Mol Cell. 2003 Dec; 12(6):1439-52.
  View in: PubMed
 
9. Li L, He F, Litofsky NS, Recht LD, Ross AH. Profiling of genes expressed by PTEN haploinsufficient neural precursor cells. Mol Cell Neurosci. 2003 Dec; 24(4):1051-61.
  View in: PubMed
 
10. Maderazo AB, Belk JP, He F, Jacobson A. Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution. Mol Cell Biol. 2003 Feb; 23(3):842-51.
  View in: PubMed
 
11. Liu H, Radhakrishnan P, Magoun L, Prabu M, Campellone KG, Savage P, He F, Schiffer CA, Leong JM. Point mutants of EHEC intimin that diminish Tir recognition and actin pedestal formation highlight a putative Tir binding pocket. Mol Microbiol. 2002 Sep; 45(6):1557-73.
  View in: PubMed
 
12. Bond AT, Mangus DA, He F, Jacobson A. Absence of Dbp2p alters both nonsense-mediated mRNA decay and rRNA processing. Mol Cell Biol. 2001 Nov; 21(21):7366-79.
  View in: PubMed
 
13. He F, Jacobson A. Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs. Mol Cell Biol. 2001 Mar; 21(5):1515-30.
  View in: PubMed
 
14. Maderazo AB, He F, Mangus DA, Jacobson A. Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p. Mol Cell Biol. 2000 Jul; 20(13):4591-603.
  View in: PubMed
 
15. Belk JP, He F, Jacobson A. Overexpression of truncated Nmd3p inhibits protein synthesis in yeast. RNA. 1999 Aug; 5(8):1055-70.
  View in: PubMed
 
16. He F, Brown AH, Jacobson A. Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway. Mol Cell Biol. 1997 Mar; 17(3):1580-94.
  View in: PubMed
 
17. He F, Brown AH, Jacobson A. Interaction between Nmd2p and Upf1p is required for activity but not for dominant-negative inhibition of the nonsense-mediated mRNA decay pathway in yeast. RNA. 1996 Feb; 2(2):153-70.
  View in: PubMed
 
18. He F, Jacobson A. Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev. 1995 Feb 15; 9(4):437-54.
  View in: PubMed
 
19. He F, Peltz SW, Donahue JL, Rosbash M, Jacobson A. Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant. Proc Natl Acad Sci U S A. 1993 Aug 1; 90(15):7034-8.
  View in: PubMed
 
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Keyword
Last Name
Institution
    
 
 
 
Co-Authors  
Amrani, Nadia
Castilla, Lucio
Jacobson, Allan
Lu, Shan
Wang, Shixia
See all (7) people
Physical Neighbors  
Goguen, Jon
Jonassen, Julie
Sato, Osamu
Dobner, Paul
Kowalik, Timothy

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