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1.
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Barres R, Kirchner H, Rasmussen M, Yan J, Kantor FR, Krook A, Näslund E, Zierath JR. Weight loss after gastric bypass surgery in human obesity remodels promoter methylation. Cell Rep. 2013 Apr 25; 3(4):1020-7.
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2.
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Ka S, Markljung E, Ring H, Albert FW, Harun-Or-Rashid M, Wahlberg P, Garcia-Roves PM, Zierath JR, Denbow DM, Pääbo S, Siegel PB, Andersson L, Hallböök F. Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight. Physiol Genomics. 2013 May 1; 45(9):367-76.
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3.
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Egan B, Zierath JR. Exercise metabolism and the molecular regulation of skeletal muscle adaptation. Cell Metab. 2013 Feb 5; 17(2):162-84.
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4.
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Fritz T, Caidahl K, Krook A, Lundström P, Mashili F, Osler M, Szekeres FL, Ostenson CG, Wändell P, Zierath JR. Effects of Nordic walking on cardiovascular risk factors in overweight individuals with type 2 diabetes, impaired or normal glucose tolerance. Diabetes Metab Res Rev. 2013 Jan; 29(1):25-32.
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5.
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Kirchner H, Osler ME, Krook A, Zierath JR. Epigenetic flexibility in metabolic regulation: disease cause and prevention? Trends Cell Biol. 2013 May; 23(5):203-9.
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6.
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Jiang LQ, Duque-Guimaraes DE, Machado UF, Zierath JR, Krook A. Altered response of skeletal muscle to IL-6 in type 2 diabetic patients. Diabetes. 2013 Feb; 62(2):355-61.
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7.
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Mashili F, Chibalin AV, Krook A, Zierath JR. Constitutive STAT3 Phosphorylation Contributes to Skeletal Muscle Insulin Resistance in Type 2 Diabetes. Diabetes. 2013 Feb; 62(2):457-65.
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8.
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de Castro Barbosa T, Jiang LQ, Zierath JR, Nunes MT. L-Arginine enhances glucose and lipid metabolism in rat L6 myotubes via the NO/ c-GMP pathway. Metabolism. 2013 Jan; 62(1):79-89.
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9.
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Szekeres F, Chadt A, Tom RZ, Deshmukh AS, Chibalin AV, Björnholm M, Al-Hasani H, Zierath JR. The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism. Am J Physiol Endocrinol Metab. 2012 Aug; 303(4):E524-33.
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10.
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Benziane B, Björnholm M, Pirkmajer S, Austin RL, Kotova O, Viollet B, Zierath JR, Chibalin AV. Activation of AMP-activated Protein Kinase Stimulates Na+,K+-ATPase Activity in Skeletal Muscle Cells. J Biol Chem. 2012 Jul 6; 287(28):23451-63.
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11.
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Barrès R, Yan J, Egan B, Treebak JT, Rasmussen M, Fritz T, Caidahl K, Krook A, O'Gorman DJ, Zierath JR. Acute exercise remodels promoter methylation in human skeletal muscle. Cell Metab. 2012 Mar 7; 15(3):405-11.
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12.
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Holmström MH, Iglesias-Gutierrez E, Zierath JR, Garcia-Roves PM. Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes. Am J Physiol Endocrinol Metab. 2012 Mar; 302(6):E731-9.
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13.
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Fritz T, Caidahl K, Osler M, Ostenson CG, Zierath JR, Wändell P. Effects of Nordic walking on health-related quality of life in overweight individuals with Type 2 diabetes mellitus, impaired or normal glucose tolerance. Diabet Med. 2011 Nov; 28(11):1362-72.
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14.
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Zierath JR. Remembering our classics: then and now. Diabetologia. 2012 Jan; 55(1):1-2.
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15.
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Yan J, Zierath JR, Barrès R. Evidence for non-CpG methylation in mammals. Exp Cell Res. 2011 Nov 1; 317(18):2555-61.
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16.
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Kulkarni SS, Karlsson HK, Szekeres F, Chibalin AV, Krook A, Zierath JR. Suppression of 5'-Nucleotidase Enzymes Promotes AMP-activated Protein Kinase (AMPK) Phosphorylation and Metabolism in Human and Mouse Skeletal Muscle. J Biol Chem. 2011 Oct 7; 286(40):34567-74.
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17.
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Kulkarni SS, Salehzadeh F, Fritz T, Zierath JR, Krook A, Osler ME. Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus. Metabolism. 2012 Feb; 61(2):175-85.
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18.
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Zierath JR, Barrès RE. Research Highlights: Nutritional status affects the epigenomic profile of peripheral blood cells. Epigenomics. 2011 Jun; 3(3):259-60.
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19.
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Mashili FL, Austin RL, Deshmukh AS, Fritz T, Caidahl K, Bergdahl K, Zierath JR, Chibalin AV, Moller DE, Kharitonenkov A, Krook A. Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity. Diabetes Metab Res Rev. 2011 Mar; 27(3):286-97.
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20.
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Egan B, Dowling P, O'Connor PL, Henry M, Meleady P, Zierath JR, O'Gorman DJ. 2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training. Proteomics. 2011 Apr; 11(8):1413-28.
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21.
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Barres R, Zierath JR. DNA methylation in metabolic disorders. Am J Clin Nutr. 2011 Apr; 93(4):897S-900S.
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22.
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Zierath JR, Krook A. [In Process Citation]. Lakartidningen. 2010 Nov 10-16; 107(45):2802-5.
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23.
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Czepluch FS, Barrès R, Caidahl K, Olieslagers S, Krook A, Rickenlund A, Zierath JR, Waltenberger J. Strenuous physical exercise adversely affects monocyte chemotaxis. Thromb Haemost. 2011 Jan 3; 105(1):122-30.
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24.
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Vind BF, Pehmøller C, Treebak JT, Birk JB, Hey-Mogensen M, Beck-Nielsen H, Zierath JR, Wojtaszewski JF, Højlund K. Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training. Diabetologia. 2011 Jan; 54(1):157-67.
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25.
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Feng X, Yan J, Wang Y, Zierath JR, Nordenskjöld M, Henter JI, Fadeel B, Zheng C. The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells. Mol Immunol. 2010 Aug; 47(14):2388-96.
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26.
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Sogaard P, Szekeres F, Garcia-Roves PM, Larsson D, Chibalin AV, Zierath JR. Spatial insulin signalling in isolated skeletal muscle preparations. J Cell Biochem. 2010 Apr 1; 109(5):943-9.
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27.
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Deshmukh AS, Long YC, de Castro Barbosa T, Karlsson HK, Glund S, Zavadoski WJ, Gibbs EM, Koistinen HA, Wallberg-Henriksson H, Zierath JR. Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle. Diabetologia. 2010 Jun; 53(6):1142-50.
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28.
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Egan B, Carson BP, Garcia-Roves PM, Chibalin AV, Sarsfield FM, Barron N, McCaffrey N, Moyna NM, Zierath JR, O'Gorman DJ. Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle. J Physiol. 2010 May 15; 588(Pt 10):1779-90.
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29.
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Cantó C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, Zierath JR, Auwerx J. Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metab. 2010 Mar 3; 11(3):213-9.
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30.
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Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L. ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth. PLoS Biol. 2009 Dec; 7(12):e1000256.
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31.
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Jiang LQ, Garcia-Roves PM, de Castro Barbosa T, Zierath JR. Constitutively active calcineurin in skeletal muscle increases endurance performance and mitochondrial respiratory capacity. Am J Physiol Endocrinol Metab. 2010 Jan; 298(1):E8-E16.
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32.
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Benziane B, Björnholm M, Lantier L, Viollet B, Zierath JR, Chibalin AV. AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase. Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1554-66.
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33.
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Deshmukh AS, Glund S, Tom RZ, Zierath JR. Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle. Am J Physiol Endocrinol Metab. 2009 Dec; 297(6):E1388-94.
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34.
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Peck GR, Chavez JA, Roach WG, Budnik BA, Lane WS, Karlsson HK, Zierath JR, Lienhard GE. Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation. J Biol Chem. 2009 Oct 30; 284(44):30016-23.
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35.
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Barrès R, Osler ME, Yan J, Rune A, Fritz T, Caidahl K, Krook A, Zierath JR. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab. 2009 Sep; 10(3):189-98.
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36.
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Rune A, Osler ME, Fritz T, Zierath JR. Regulation of skeletal muscle sucrose, non-fermenting 1/AMP-activated protein kinase-related kinase (SNARK) by metabolic stress and diabetes. Diabetologia. 2009 Oct; 52(10):2182-9.
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37.
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Wallberg-Henriksson H, Zierath JR. A new twist on brown fat metabolism. Cell. 2009 Apr 3; 137(1):22-4.
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38.
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Krook A, Zierath JR. Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA. Diabetologia. 2009 Jul; 52(7):1231-9.
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39.
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Egan B, Zierath JR. Hunting for the SNARK in metabolic disease. Am J Physiol Endocrinol Metab. 2009 May; 296(5):E969-72.
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40.
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Sultan A, Strodthoff D, Robertson AK, Paulsson-Berne G, Fauconnier J, Parini P, Rydén M, Thierry-Mieg N, Johansson ME, Chibalin AV, Zierath JR, Arner P, Hansson GK. T cell-mediated inflammation in adipose tissue does not cause insulin resistance in hyperlipidemic mice. Circ Res. 2009 Apr 24; 104(8):961-8.
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41.
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Treebak JT, Frøsig C, Pehmøller C, Chen S, Maarbjerg SJ, Brandt N, MacKintosh C, Zierath JR, Hardie DG, Kiens B, Richter EA, Pilegaard H, Wojtaszewski JF. Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle. Diabetologia. 2009 May; 52(5):891-900.
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42.
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Karlsson HK, Chibalin AV, Koistinen HA, Yang J, Koumanov F, Wallberg-Henriksson H, Zierath JR, Holman GD. Kinetics of GLUT4 trafficking in rat and human skeletal muscle. Diabetes. 2009 Apr; 58(4):847-54.
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43.
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Chadt A, Leicht K, Deshmukh A, Jiang LQ, Scherneck S, Bernhardt U, Dreja T, Vogel H, Schmolz K, Kluge R, Zierath JR, Hultschig C, Hoeben RC, Schürmann A, Joost HG, Al-Hasani H. Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity. Nat Genet. 2008 Nov; 40(11):1354-9.
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44.
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Garcia-Roves PM, Osler ME, Holmström MH, Zierath JR. Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle. J Biol Chem. 2008 Dec 19; 283(51):35724-34.
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45.
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Kuoppamaa H, Skrobuk P, Sihvo M, Hiukka A, Chibalin AV, Zierath JR, Koistinen HA. Globular adiponectin stimulates glucose transport in type 2 diabetic muscle. Diabetes Metab Res Rev. 2008 Oct; 24(7):554-62.
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46.
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Benziane B, Burton TJ, Scanlan B, Galuska D, Canny BJ, Chibalin AV, Zierath JR, Stepto NK. Divergent cell signaling after short-term intensified endurance training in human skeletal muscle. Am J Physiol Endocrinol Metab. 2008 Dec; 295(6):E1427-38.
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47.
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Glund S, Treebak JT, Long YC, Barres R, Viollet B, Wojtaszewski JF, Zierath JR. Role of adenosine 5'-monophosphate-activated protein kinase in interleukin-6 release from isolated mouse skeletal muscle. Endocrinology. 2009 Feb; 150(2):600-6.
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48.
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Deshmukh AS, Hawley JA, Zierath JR. Exercise-induced phospho-proteins in skeletal muscle. Int J Obes (Lond). 2008 Sep; 32 Suppl 4:S18-23.
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49.
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Lundholm L, Bryzgalova G, Gao H, Portwood N, Fält S, Berndt KD, Dicker A, Galuska D, Zierath JR, Gustafsson JA, Efendic S, Dahlman-Wright K, Khan A. The estrogen receptor {alpha}-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice; potential molecular mechanisms. J Endocrinol. 2008 Nov; 199(2):275-86.
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50.
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Vieira E, Nilsson EC, Nerstedt A, Ormestad M, Long YC, Garcia-Roves PM, Zierath JR, Mahlapuu M. Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle. Am J Physiol Endocrinol Metab. 2008 Nov; 295(5):E1032-7.
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51.
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Long YC, Zierath JR. Influence of AMP-activated protein kinase and calcineurin on metabolic networks in skeletal muscle. Am J Physiol Endocrinol Metab. 2008 Sep; 295(3):E545-52.
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52.
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Cabrera O, Jacques-Silva MC, Speier S, Yang SN, Köhler M, Fachado A, Vieira E, Zierath JR, Kibbey R, Berman DM, Kenyon NS, Ricordi C, Caicedo A, Berggren PO. Glutamate is a positive autocrine signal for glucagon release. Cell Metab. 2008 Jun; 7(6):545-54.
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53.
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Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A. siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle. Diabetes. 2008 Aug; 57(8):2066-73.
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54.
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Bouzakri K, Austin R, Rune A, Lassman ME, Garcia-Roves PM, Berger JP, Krook A, Chibalin AV, Zhang BB, Zierath JR. Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle. Diabetes. 2008 Jun; 57(6):1508-16.
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55.
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Deshmukh AS, Treebak JT, Long YC, Viollet B, Wojtaszewski JF, Zierath JR. Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling. Mol Endocrinol. 2008 May; 22(5):1105-12.
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56.
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Chibalin AV, Leng Y, Vieira E, Krook A, Björnholm M, Long YC, Kotova O, Zhong Z, Sakane F, Steiler T, Nylén C, Wang J, Laakso M, Topham MK, Gilbert M, Wallberg-Henriksson H, Zierath JR. Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. Cell. 2008 Feb 8; 132(3):375-86.
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57.
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Osler ME, Zierath JR. Adenosine 5'-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle. Endocrinology. 2008 Mar; 149(3):935-41.
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58.
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Zierath JR. Xth International Symposium on insulin receptors and insulin action. Acta Physiol (Oxf). 2008 Jan; 192(1):1.
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59.
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Osler ME, Zierath JR. Fighting the battle of the bulge: exercise training in early-onset type 2 diabetes. Diabetologia. 2007 Jul; 50(7):1362-4.
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60.
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Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK. TXNIP regulates peripheral glucose metabolism in humans. PLoS Med. 2007 May; 4(5):e158.
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61.
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Glund S, Deshmukh A, Long YC, Moller T, Koistinen HA, Caidahl K, Zierath JR, Krook A. Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle. Diabetes. 2007 Jun; 56(6):1630-7.
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62.
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Hu X, Feng Y, Liu X, Zhao XF, Yu JH, Yang YS, Sydow-Bäckman M, Hörling J, Zierath JR, Leng Y. Effect of a novel non-thiazolidinedione peroxisome proliferator-activated receptor alpha/gamma agonist on glucose uptake. Diabetologia. 2007 May; 50(5):1048-57.
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63.
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Zierath JR. The path to insulin resistance: paved with ceramides? Cell Metab. 2007 Mar; 5(3):161-3.
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64.
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Bouzakri K, Zierath JR. MAP4K4 gene silencing in human skeletal muscle prevents tumor necrosis factor-alpha-induced insulin resistance. J Biol Chem. 2007 Mar 16; 282(11):7783-9.
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65.
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Karlsson HK, Zierath JR. Insulin signaling and glucose transport in insulin resistant human skeletal muscle. Cell Biochem Biophys. 2007; 48(2-3):103-13.
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66.
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Long YC, Glund S, Garcia-Roves PM, Zierath JR. Calcineurin regulates skeletal muscle metabolism via coordinated changes in gene expression. J Biol Chem. 2007 Jan 19; 282(3):1607-14.
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67.
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Fritz T, Krämer DK, Karlsson HK, Galuska D, Engfeldt P, Zierath JR, Krook A. Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev. 2006 Nov-Dec; 22(6):492-8.
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68.
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Wang J, Shafqat J, Hall K, Ståhlberg M, Wivall-Helleryd IL, Bouzakri K, Zierath JR, Brismar K, Jörnvall H, Lewitt MS. Specific cleavage of insulin-like growth factor-binding protein-1 by a novel protease activity. Cell Mol Life Sci. 2006 Oct; 63(19-20):2405-14.
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69.
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O'Gorman DJ, Karlsson HK, McQuaid S, Yousif O, Rahman Y, Gasparro D, Glund S, Chibalin AV, Zierath JR, Nolan JJ. Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes. Diabetologia. 2006 Dec; 49(12):2983-92.
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70.
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Treebak JT, Glund S, Deshmukh A, Klein DK, Long YC, Jensen TE, Jørgensen SB, Viollet B, Andersson L, Neumann D, Wallimann T, Richter EA, Chibalin AV, Zierath JR, Wojtaszewski JF. AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits. Diabetes. 2006 Jul; 55(7):2051-8.
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71.
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Bouzakri K, Zachrisson A, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR. siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Cell Metab. 2006 Jul; 4(1):89-96.
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72.
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Long YC, Zierath JR. AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest. 2006 Jul; 116(7):1776-83.
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73.
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Deshmukh A, Coffey VG, Zhong Z, Chibalin AV, Hawley JA, Zierath JR. Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle. Diabetes. 2006 Jun; 55(6):1776-82.
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74.
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Cantó C, Chibalin AV, Barnes BR, Glund S, Suárez E, Ryder JW, Palacín M, Zierath JR, Zorzano A, Gumà A. Neuregulins mediate calcium-induced glucose transport during muscle contraction. J Biol Chem. 2006 Aug 4; 281(31):21690-7.
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75.
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Karlsson HK, Ahlsén M, Zierath JR, Wallberg-Henriksson H, Koistinen HA. Insulin signaling and glucose transport in skeletal muscle from first-degree relatives of type 2 diabetic patients. Diabetes. 2006 May; 55(5):1283-8.
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76.
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Bouzakri K, Karlsson HK, Vestergaard H, Madsbad S, Christiansen E, Zierath JR. IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients. Diabetes. 2006 Mar; 55(3):785-91.
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77.
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Bryzgalova G, Gao H, Ahren B, Zierath JR, Galuska D, Steiler TL, Dahlman-Wright K, Nilsson S, Gustafsson JA, Efendic S, Khan A. Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver. Diabetologia. 2006 Mar; 49(3):588-97.
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78.
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Nilsson EC, Long YC, Martinsson S, Glund S, Garcia-Roves P, Svensson LT, Andersson L, Zierath JR, Mahlapuu M. Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice. J Biol Chem. 2006 Mar 17; 281(11):7244-52.
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79.
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Kannisto K, Chibalin A, Glinghammar B, Zierath JR, Hamsten A, Ehrenborg E. Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise. Int J Mol Med. 2006 Jan; 17(1):45-52.
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80.
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Hawley JA, Hargreaves M, Zierath JR. Signalling mechanisms in skeletal muscle: role in substrate selection and muscle adaptation. Essays Biochem. 2006; 42:1-12.
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81.
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Barnes BR, Long YC, Steiler TL, Leng Y, Galuska D, Wojtaszewski JF, Andersson L, Zierath JR. Changes in exercise-induced gene expression in 5'-AMP-activated protein kinase gamma3-null and gamma3 R225Q transgenic mice. Diabetes. 2005 Dec; 54(12):3484-9.
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82.
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Long YC, Zierath JR. Fine-tuning insulin and nitric oxide signalling by turning up the AMPs: new insights into AMP-activated protein kinase signalling. Diabetologia. 2005 Dec; 48(12):2451-3.
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83.
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Coffey VG, Zhong Z, Shield A, Canny BJ, Chibalin AV, Zierath JR, Hawley JA. Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans. FASEB J. 2006 Jan; 20(1):190-2.
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84.
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Long YC, Barnes BR, Mahlapuu M, Steiler TL, Martinsson S, Leng Y, Wallberg-Henriksson H, Andersson L, Zierath JR. Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle. Diabetologia. 2005 Nov; 48(11):2354-64.
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85.
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Plomgaard P, Bouzakri K, Krogh-Madsen R, Mittendorfer B, Zierath JR, Pedersen BK. Tumor necrosis factor-alpha induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation. Diabetes. 2005 Oct; 54(10):2939-45.
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86.
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99.
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Zierath JR, Hawley JA. Skeletal muscle fiber type: influence on contractile and metabolic properties. PLoS Biol. 2004 Oct; 2(10):e348.
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100.
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Krook A, Wallberg-Henriksson H, Zierath JR. Sending the signal: molecular mechanisms regulating glucose uptake. Med Sci Sports Exerc. 2004 Jul; 36(7):1212-7.
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105.
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Karlsson HK, Nilsson PA, Nilsson J, Chibalin AV, Zierath JR, Blomstrand E. Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise. Am J Physiol Endocrinol Metab. 2004 Jul; 287(1):E1-7.
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Storgaard H, Jensen CB, Björnholm M, Song XM, Madsbad S, Zierath JR, Vaag AA. Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes. J Clin Endocrinol Metab. 2004 Mar; 89(3):1301-11.
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Al-Khalili L, Chibalin AV, Yu M, Sjödin B, Nylén C, Zierath JR, Krook A. MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways. Am J Physiol Cell Physiol. 2004 Jun; 286(6):C1410-6.
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110.
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Koistinen HA, Forsgren M, Wallberg-Henriksson H, Zierath JR. Insulin action on expression of novel adipose genes in healthy and type 2 diabetic subjects. Obes Res. 2004 Jan; 12(1):25-31.
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111.
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Hawley JA, Zierath JR. Integration of metabolic and mitogenic signal transduction in skeletal muscle. Exerc Sport Sci Rev. 2004 Jan; 32(1):4-8.
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Zierath JR, Kawano Y. The effect of hyperglycaemia on glucose disposal and insulin signal transduction in skeletal muscle. Best Pract Res Clin Endocrinol Metab. 2003 Sep; 17(3):385-98.
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Koistinen HA, Chibalin AV, Zierath JR. Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients. Diabetologia. 2003 Oct; 46(10):1324-8.
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Steiler TL, Galuska D, Leng Y, Chibalin AV, Gilbert M, Zierath JR. Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats. Endocrinology. 2003 Dec; 144(12):5259-67.
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Lake S, Krook A, Zierath JR. Analysis of insulin signaling pathways through comparative genomics. Mapping mechanisms for insulin resistance in type 2 (non-insulin-dependent) diabetes mellitus. Exp Clin Endocrinol Diabetes. 2003 Jun; 111(4):191-7.
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Al-Khalili L, Chibalin AV, Kannisto K, Zhang BB, Permert J, Holman GD, Ehrenborg E, Ding VD, Zierath JR, Krook A. Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content. Cell Mol Life Sci. 2003 May; 60(5):991-8.
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Yu M, Stepto NK, Chibalin AV, Fryer LG, Carling D, Krook A, Hawley JA, Zierath JR. Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. J Physiol. 2003 Jan 15; 546(Pt 2):327-35.
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Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB. Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle. Diabetes. 1999 Feb; 48(2):310-20.
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173.
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Chibalin AV, Zierath JR, Katz AI, Berggren PO, Bertorello AM. Phosphatidylinositol 3-kinase-mediated endocytosis of renal Na+, K+-ATPase alpha subunit in response to dopamine. Mol Biol Cell. 1998 May; 9(5):1209-20.
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174.
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Zierath JR, Krook A, Wallberg-Henriksson H. Insulin action in skeletal muscle from patients with NIDDM. Mol Cell Biochem. 1998 May; 182(1-2):153-60.
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175.
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Zierath JR, Frevert EU, Ryder JW, Berggren PO, Kahn BB. Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes. Diabetes. 1998 Jan; 47(1):1-4.
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176.
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Wallberg-Henriksson H, Rincon J, Zierath JR. Exercise in the management of non-insulin-dependent diabetes mellitus. Sports Med. 1998 Jan; 25(1):25-35.
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177.
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Galuska D, Ryder J, Kawano Y, Charron MJ, Zierath JR. Insulin signaling and glucose transport in insulin resistant skeletal muscle. Special reference to GLUT4 transgenic and GLUT4 knockout mice. Adv Exp Med Biol. 1998; 441:73-85.
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178.
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Lund S, Holman GD, Zierath JR, Rincon J, Nolte LA, Clark AE, Schmitz O, Pedersen O, Wallberg-Henriksson H. Effect of insulin on GLUT4 cell surface content and turnover rate in human skeletal muscle as measured by the exofacial bis-mannose photolabeling technique. Diabetes. 1997 Dec; 46(12):1965-9.
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179.
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Krook A, Kawano Y, Song XM, Efendic S, Roth RA, Wallberg-Henriksson H, Zierath JR. Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats. Diabetes. 1997 Dec; 46(12):2110-4.
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180.
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Shepherd PR, Nave BT, Rincon J, Haigh RJ, Foulstone E, Proud C, Zierath JR, Siddle K, Wallberg-Henriksson H. Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism. Diabetologia. 1997 Oct; 40(10):1172-7.
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181.
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Charron MJ, Katz EB, Zierath JR. Metabolic and molecular consequences of modifying GLUT4 expression in skeletal muscle. Biochem Soc Trans. 1997 Aug; 25(3):963-8.
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182.
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Lund S, Pedersen O, Holman GD, Clark AE, Zierath JR, Wallberg-Henriksson H. GLUT4 translocation in human muscle strips. Biochem Soc Trans. 1997 Aug; 25(3):466S.
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183.
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Tsao TS, Stenbit AE, Li J, Houseknecht KL, Zierath JR, Katz EB, Charron MJ. Muscle-specific transgenic complementation of GLUT4-deficient mice. Effects on glucose but not lipid metabolism. J Clin Invest. 1997 Aug 1; 100(3):671-7.
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184.
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Shepherd PR, Navé BT, Rincon J, Nolte LA, Bevan AP, Siddle K, Zierath JR, Wallberg-Henriksson H. Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle. J Biol Chem. 1997 Jul 25; 272(30):19000-7.
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185.
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Björnholm M, Kawano Y, Lehtihet M, Zierath JR. Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes. 1997 Mar; 46(3):524-7.
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186.
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Zierath JR, Houseknecht KL, Gnudi L, Kahn BB. High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect. Diabetes. 1997 Feb; 46(2):215-23.
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187.
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Zierath JR, He L, Gumà A, Odegoard Wahlström E, Klip A, Wallberg-Henriksson H. Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM. Diabetologia. 1996 Oct; 39(10):1180-9.
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188.
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Aksnes AK, Hjeltnes N, Wahlström EO, Katz A, Zierath JR, Wallberg-Henriksson H. Intact glucose transport in morphologically altered denervated skeletal muscle from quadriplegic patients. Am J Physiol. 1996 Sep; 271(3 Pt 1):E593-600.
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189.
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Wahren J, Johansson BL, Wallberg-Henriksson H, Linde B, Fernqvist-Forbes E, Zierath JR. C-peptide revisited--new physiological effects and therapeutic implications. J Intern Med. 1996 Sep; 240(3):115-24.
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190.
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Houseknecht KL, Zhu AX, Gnudi L, Hamann A, Zierath JR, Tozzo E, Flier JS, Kahn BB. Overexpression of Ha-ras selectively in adipose tissue of transgenic mice. Evidence for enhanced sensitivity to insulin. J Biol Chem. 1996 May 10; 271(19):11347-55.
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191.
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Rincon J, Holmäng A, Wahlström EO, Lönnroth P, Björntorp P, Zierath JR, Wallberg-Henriksson H. Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment. Diabetes. 1996 May; 45(5):615-21.
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192.
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Zierath JR, Handberg A, Tally M, Wallberg-Henriksson H. C-peptide stimulates glucose transport in isolated human skeletal muscle independent of insulin receptor and tyrosine kinase activation. Diabetologia. 1996 Mar; 39(3):306-13.
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193.
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Nolte LA, Rincón J, Wahlström EO, Craig BW, Zierath JR, Wallberg-Henriksson H. Hyperglycemia activates glucose transport in rat skeletal muscle via a Ca(2+)-dependent mechanism. Diabetes. 1995 Nov; 44(11):1345-8.
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194.
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Zierath JR, Nolte LA, Wahlström E, Galuska D, Shepherd PR, Kahn BB, Wallberg-Henriksson H. Carrier-mediated fructose uptake significantly contributes to carbohydrate metabolism in human skeletal muscle. Biochem J. 1995 Oct 15; 311 ( Pt 2):517-21.
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195.
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Gumà A, Zierath JR, Wallberg-Henriksson H, Klip A. Insulin induces translocation of GLUT-4 glucose transporters in human skeletal muscle. Am J Physiol. 1995 Apr; 268(4 Pt 1):E613-22.
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196.
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Nolte LA, Abdel-Halim SM, Martin IK, Guenifi A, Zierath JR, Ostenson CG, Wallberg-Henriksson H. Development of decreased insulin-induced glucose transport in skeletal muscle of glucose-intolerant hybrids of diabetic GK rats. Clin Sci (Lond). 1995 Mar; 88(3):301-6.
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197.
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Echwald SM, Bjørbaek C, Hansen T, Clausen JO, Vestergaard H, Zierath JR, Printz RL, Granner DK, Pedersen O. Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity. Diabetes. 1995 Mar; 44(3):347-53.
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198.
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Zierath JR. In vitro studies of human skeletal muscle: hormonal and metabolic regulation of glucose transport. Acta Physiol Scand Suppl. 1995; 626:1-96.
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199.
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Galuska D, Nolte L, Wahlström E, Smedegaard Kristensen JS, Wallberg-Henriksson H, Zierath JR. Effects of non-esterified fatty acids on insulin-stimulated glucose transport in isolated skeletal muscle from patients with type 2 (non-insulin-dependent) diabetes mellitus. Acta Diabetol. 1994 Sep; 31(3):169-72.
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200.
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Galuska D, Nolte LA, Zierath JR, Wallberg-Henriksson H. Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM. Diabetologia. 1994 Aug; 37(8):826-32.
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201.
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Bjørbaek C, Echwald SM, Hubricht P, Vestergaard H, Hansen T, Zierath J, Pedersen O. Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM. Diabetes. 1994 Aug; 43(8):976-83.
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202.
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Nolte LA, Galuska D, Martin IK, Zierath JR, Wallberg-Henriksson H. Elevated free fatty acid levels inhibit glucose phosphorylation in slow-twitch rat skeletal muscle. Acta Physiol Scand. 1994 May; 151(1):51-9.
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203.
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Zierath JR, Galuska D, Nolte LA, Thörne A, Kristensen JS, Wallberg-Henriksson H. Effects of glycaemia on glucose transport in isolated skeletal muscle from patients with NIDDM: in vitro reversal of muscular insulin resistance. Diabetologia. 1994 Mar; 37(3):270-7.
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204.
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Norgren S, Zierath J, Wedell A, Wallberg-Henriksson H, Luthman H. Regulation of human insulin receptor RNA splicing in vivo. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1465-9.
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205.
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Johansson U, Eriksson LS, Galuska D, Zierath JR, Wallberg-Henriksson H. Insulin action on glucose transport in isolated skeletal muscle from patients with liver cirrhosis. Scand J Gastroenterol. 1994 Jan; 29(1):71-6.
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206.
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Norgren S, Zierath J, Galuska D, Wallberg-Henriksson H, Luthman H. Differences in the ratio of RNA encoding two isoforms of the insulin receptor between control and NIDDM patients. The RNA variant without Exon 11 predominates in both groups. Diabetes. 1993 May; 42(5):675-81.
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207.
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Zierath JR, Wallberg-Henriksson H. Exercise training in obese diabetic patients. Special considerations. Sports Med. 1992 Sep; 14(3):171-89.
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208.
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Zierath JR, Bang P, Galuska D, Hall K, Wallberg-Henriksson H. Insulin-like growth factor II stimulates glucose transport in human skeletal muscle. FEBS Lett. 1992 Aug 3; 307(3):379-82.
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209.
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Snyder A, Zierath JR, Hawley JA, Sleeper MD, Craig BW. The effects of exercise mode, swimming vs. running, upon bone growth in the rapidly growing female rat. Mech Ageing Dev. 1992; 66(1):59-69.
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210.
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Zierath JR, Galuska D, Engström A, Johnson KH, Betsholtz C, Westermark P, Wallberg-Henriksson H. Human islet amyloid polypeptide at pharmacological levels inhibits insulin and phorbol ester-stimulated glucose transport in in vitro incubated human muscle strips. Diabetologia. 1992 Jan; 35(1):26-31.
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211.
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Zierath JR, Galuska D, Johansson BL, Wallberg-Henriksson H. Effect of human C-peptide on glucose transport in in vitro incubated human skeletal muscle. Diabetologia. 1991 Dec; 34(12):899-901.
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212.
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Galuska D, Zierath J, Thörne A, Sonnenfeld T, Wallberg-Henriksson H. Metformin increases insulin-stimulated glucose transport in insulin-resistant human skeletal muscle. Diabete Metab. 1991 May; 17(1 Pt 2):159-63.
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213.
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Gulve EA, Cartee GD, Zierath JR, Corpus VM, Holloszy JO. Reversal of enhanced muscle glucose transport after exercise: roles of insulin and glucose. Am J Physiol. 1990 Nov; 259(5 Pt 1):E685-91.
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214.
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Henriksen EJ, Sleeper MD, Zierath JR, Holloszy JO. Polymyxin B inhibits stimulation of glucose transport in muscle by hypoxia or contractions. Am J Physiol. 1989 May; 256(5 Pt 1):E662-7.
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215.
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Cartee GD, Young DA, Sleeper MD, Zierath J, Wallberg-Henriksson H, Holloszy JO. Prolonged increase in insulin-stimulated glucose transport in muscle after exercise. Am J Physiol. 1989 Apr; 256(4 Pt 1):E494-9.
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216.
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Kaiserauer S, Snyder AC, Sleeper M, Zierath J. Nutritional, physiological, and menstrual status of distance runners. Med Sci Sports Exerc. 1989 Apr; 21(2):120-5.
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