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1.
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Houghton JM. Introduction. Methods Mol Biol. 2012; 921:1-5.
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2.
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Moore N, Houghton J, Lyle S. Slow-cycling therapy-resistant cancer cells. Stem Cells Dev. 2012 Jul 1; 21(10):1822-30.
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3.
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Hutchinson L, Stenstrom B, Chen D, Piperdi B, Levey S, Lyle S, Wang TC, Houghton J. Human Barrett's Adenocarcinoma of the Esophagus, Associated Myofibroblasts, and Endothelium Can Arise from Bone Marrow-Derived Cells After Allogeneic Stem Cell Transplant. Stem Cells Dev. 2011 Jan; 20(1):11-7.
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4.
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Houghton J, Li H, Fan X, Liu Y, Liu JH, Rao VP, Poutahidis T, Taylor CL, Jackson EA, Hewes C, Lyle S, Cerny A, Bowen G, Cerny J, Moore N, Kurt-Jones EA, Erdman SE. Mutations in bone marrow-derived stromal stem cells unmask latent malignancy. Stem Cells Dev. 2010 Aug; 19(8):1153-66.
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5.
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Martin J, Donnelly JM, Houghton J, Zavros Y. The role of sonic hedgehog reemergence during gastric cancer. Dig Dis Sci. 2010 Jun; 55(6):1516-24.
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6.
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Cerny J, Trneny M, Slavickova A, Pytlik R, Salkova J, Valkova V, Liu Q, Houghton J, Klener P. Rituximab based therapy followed by autologous stem cell transplantation leads to superior outcome and high rates of PCR negativity in patients with indolent B-cell lymphoproliferative disorders. Hematology. 2009 Aug; 14(4):187-97.
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7.
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Stoicov C, Fan X, Liu JH, Bowen G, Whary M, Kurt-Jones E, Houghton J. T-bet knockout prevents Helicobacter felis-induced gastric cancer. J Immunol. 2009 Jul 1; 183(1):642-9.
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8.
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Li H, Fan X, Stoicov C, Liu JH, Zubair S, Tsai E, Ste Marie R, Wang TC, Lyle S, Kurt-Jones E, Houghton J. Human and mouse colon cancer utilizes CD95 signaling for local growth and metastatic spread to liver. Gastroenterology. 2009 Sep; 137(3):934-44, 944.e1-4.
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9.
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Stoicov C, Saffari R, Houghton J. Green tea inhibits Helicobacter growth in vivo and in vitro. Int J Antimicrob Agents. 2009 May; 33(5):473-8.
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10.
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Rogers AB, Houghton J. Helicobacter-based mouse models of digestive system carcinogenesis. Methods Mol Biol. 2009; 511:267-95.
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11.
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Li H, Fan X, Kovi RC, Jo Y, Moquin B, Konz R, Stoicov C, Kurt-Jones E, Grossman SR, Lyle S, Rogers AB, Montrose M, Houghton J. Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: a model of age-related tumorigenesis in mice. Cancer Res. 2007 Nov 15; 67(22):10889-98.
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12.
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Li H, Cai X, Fan X, Moquin B, Stoicov C, Houghton J. Fas Ag-FasL coupling leads to ERK1/2-mediated proliferation of gastric mucosal cells. Am J Physiol Gastrointest Liver Physiol. 2008 Jan; 294(1):G263-75.
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13.
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Correa P, Houghton J. Carcinogenesis of Helicobacter pylori. Gastroenterology. 2007 Aug; 133(2):659-72.
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14.
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Li H, Fan X, Houghton J. Tumor microenvironment: the role of the tumor stroma in cancer. J Cell Biochem. 2007 Jul 1; 101(4):805-15.
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15.
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Houghton J. Bone-marrow-derived cells and cancer--an opportunity for improved therapy. Nat Clin Pract Oncol. 2007 Jan; 4(1):2-3.
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16.
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Kurt-Jones EA, Cao L, Sandor F, Rogers AB, Whary MT, Nambiar PR, Cerny A, Bowen G, Yan J, Takaishi S, Chi AL, Reed G, Houghton J, Fox JG, Wang TC. Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses. Infect Immun. 2007 Jan; 75(1):471-80.
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17.
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Cui G, Takaishi S, Ai W, Betz KS, Florholmen J, Koh TJ, Houghton J, Pritchard DM, Wang TC. Gastrin-induced apoptosis contributes to carcinogenesis in the stomach. Lab Invest. 2006 Oct; 86(10):1037-51.
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18.
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Houghton J, Morozov A, Smirnova I, Wang TC. Stem cells and cancer. Semin Cancer Biol. 2007 Jun; 17(3):191-203.
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19.
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Li HC, Stoicov C, Rogers AB, Houghton J. Stem cells and cancer: evidence for bone marrow stem cells in epithelial cancers. World J Gastroenterol. 2006 Jan 21; 12(3):363-71.
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20.
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Stoicov C, Li H, Carlson J, Houghton J. Bone marrow cells as the origin of stomach cancer. Future Oncol. 2005 Dec; 1(6):851-62.
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21.
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Cai X, Stoicov C, Li H, Carlson J, Whary M, Fox JG, Houghton J. Overcoming Fas-mediated apoptosis accelerates Helicobacter-induced gastric cancer in mice. Cancer Res. 2005 Dec 1; 65(23):10912-20.
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22.
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Stoicov C, Cai X, Li H, Klucevsek K, Carlson J, Saffari R, Houghton J. Major histocompatibility complex class II inhibits fas antigen-mediated gastric mucosal cell apoptosis through actin-dependent inhibition of receptor aggregation. Infect Immun. 2005 Oct; 73(10):6311-21.
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23.
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Cai X, Carlson J, Stoicov C, Li H, Wang TC, Houghton J. Helicobacter felis eradication restores normal architecture and inhibits gastric cancer progression in C57BL/6 mice. Gastroenterology. 2005 Jun; 128(7):1937-52.
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24.
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Takaishi S, Cui G, Frederick DM, Carlson JE, Houghton J, Varro A, Dockray GJ, Ge Z, Whary MT, Rogers AB, Fox JG, Wang TC. Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer. Gastroenterology. 2005 Jun; 128(7):1965-83.
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25.
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Houghton J, Wang TC. Helicobacter pylori and gastric cancer: a new paradigm for inflammation-associated epithelial cancers. Gastroenterology. 2005 May; 128(6):1567-78.
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26.
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Houghton J, Stoicov C, Nomura S, Rogers AB, Carlson J, Li H, Cai X, Fox JG, Goldenring JR, Wang TC. Gastric cancer originating from bone marrow-derived cells. Science. 2004 Nov 26; 306(5701):1568-71.
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27.
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Mandell L, Moran AP, Cocchiarella A, Houghton J, Taylor N, Fox JG, Wang TC, Kurt-Jones EA. Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4. Infect Immun. 2004 Nov; 72(11):6446-54.
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28.
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Stoicov C, Saffari R, Cai X, Hasyagar C, Houghton J. Molecular biology of gastric cancer: Helicobacter infection and gastric adenocarcinoma: bacterial and host factors responsible for altered growth signaling. Gene. 2004 Oct 27; 341:1-17.
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29.
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Stoicov C, Whary M, Rogers AB, Lee FS, Klucevsek K, Li H, Cai X, Saffari R, Ge Z, Khan IA, Combe C, Luster A, Fox JG, Houghton J. Coinfection modulates inflammatory responses and clinical outcome of Helicobacter felis and Toxoplasma gondii infections. J Immunol. 2004 Sep 1; 173(5):3329-36.
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30.
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Koh TJ, Field JK, Varro A, Liloglou T, Fielding P, Cui G, Houghton J, Dockray GJ, Wang TC. Glycine-extended gastrin promotes the growth of lung cancer. Cancer Res. 2004 Jan 1; 64(1):196-201.
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31.
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Li H, Stoicov C, Cai X, Wang TC, Houghton J. Helicobacter and gastric cancer disease mechanisms: host response and disease susceptibility. Curr Gastroenterol Rep. 2003 Dec; 5(6):459-67.
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32.
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Zivny J, Wang TC, Yantiss R, Kim KH, Houghton J. Role of therapy or monitoring in preventing progression to gastric cancer. J Clin Gastroenterol. 2003 May-Jun; 36(5 Suppl):S50-60; discussion S61-2.
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33.
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Houghton J, Fox JG, Wang TC. Gastric cancer: laboratory bench to clinic. J Gastroenterol Hepatol. 2002 Apr; 17(4):495-502.
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34.
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Houghton J, Ramamoorthy R, Pandya H, Dhirmalani R, Kim KH. Human plasma is directly bacteriocidal against Helicobacter pylori in vitro, potentially explaining the decreased detection of Helicobacter pylori during acute upper GI bleeding. Gastrointest Endosc. 2002 Jan; 55(1):11-6.
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35.
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Houghton PJ, Rahman A, Will CL, Dolnick BJ, Houghton JA. Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates. Cancer Res. 1992 Feb 1; 52(3):558-65.
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36.
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Houghton PJ, Germain GS, Hazelton BJ, Pennington JW, Houghton JA. Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency. Proc Natl Acad Sci U S A. 1989 Feb; 86(4):1377-81.
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37.
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Douglass EC, Valentine M, Etcubanas E, Parham D, Webber BL, Houghton PJ, Houghton JA, Green AA. A specific chromosomal abnormality in rhabdomyosarcoma. Cytogenet Cell Genet. 1987; 45(3-4):148-55.
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