Gary R Ostroff PHD
Title Research Professor
Institution University of Massachusetts Medical School
Department Program in Molecular Medicine
Address University of Massachusetts Medical School
373 Plantation Street
Worcester MA 01605
Telephone 508-856-1930
Email
Other Positions
Institution UMMS - School of Medicine
Department Pediatrics

Institution UMMS - Graduate School of Biomedical Sciences
Department Interdisciplinary Graduate Program

Institution UMMS - Graduate School of Biomedical Sciences
Department Masters in Clinical Investigation

Institution UMMS - Programs, Centers and Institutes
Department RNA Therapeutics Institute
Publications
1. Hurtgen BJ, Hung CY, Ostroff GR, Levitz SM, Cole GT. Construction and Evaluation of a Novel Recombinant T Cell Epitope-Based Vaccine against Coccidioidomycosis. Infect Immun. 2012 Nov; 80(11):3960-74.
  View in: PubMed
 
2. Huang H, Ostroff GR, Lee CK, Agarwal S, Ram S, Rice PA, Specht CA, Levitz SM. Relative Contributions of Dectin-1 and Complement to Immune Responses to Particulate ß-Glucans. J Immunol. 2012 May 30.
  View in: PubMed
 
3. Soto ER, Caras AC, Kut LC, Castle MK, Ostroff GR. Glucan particles for macrophage targeted delivery of nanoparticles. J Drug Deliv. 2012; 2012:143524.
  View in: PubMed
 
4. Agarwal S, Specht CA, Haibin H, Ostroff GR, Ram S, Rice PA, Levitz SM. Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans. MBio. 2011; 2(5).
  View in: PubMed
 
5. Tesz GJ, Aouadi M, Prot M, Nicoloro SM, Boutet E, Amano SU, Goller A, Wang M, Guo CA, Salomon WE, Virbasius JV, Baum RA, O'Connor MJ, Soto E, Ostroff GR, Czech MP. Glucan particles for selective delivery of siRNA to phagocytic cells in mice. Biochem J. 2011 Jun 1; 436(2):351-62.
  View in: PubMed
 
6. Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM. Robust Stimulation of Humoral and Cellular Immune Responses following Vaccination with Antigen-Loaded beta-Glucan Particles. MBio. 2010; 1(3).
  View in: PubMed
 
7. Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature. 2009 Apr 30; 458(7242):1180-4.
  View in: PubMed
 
8. Huang H, Ostroff GR, Lee CK, Wang JP, Specht CA, Levitz SM. Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists. Infect Immun. 2009 May; 77(5):1774-81.
  View in: PubMed
 
9. Soto ER, Ostroff GR. Characterization of multilayered nanoparticles encapsulated in yeast cell wall particles for DNA delivery. Bioconjug Chem. 2008 Apr; 19(4):840-8.
  View in: PubMed
 
10. Young SH, Ostroff GR, Zeidler-Erdely PC, Roberts JR, Antonini JM, Castranova V. A comparison of the pulmonary inflammatory potential of different components of yeast cell wall. J Toxicol Environ Health A. 2007 Jul; 70(13):1116-24.
  View in: PubMed
 
11. Hong F, Yan J, Baran JT, Allendorf DJ, Hansen RD, Ostroff GR, Xing PX, Cheung NK, Ross GD. Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J Immunol. 2004 Jul 15; 173(2):797-806.
  View in: PubMed
 
12. Hong F, Hansen RD, Yan J, Allendorf DJ, Baran JT, Ostroff GR, Ross GD. Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells. Cancer Res. 2003 Dec 15; 63(24):9023-31.
  View in: PubMed
 
13. Donzelli BG, Ostroff G, Harman GE. Enhanced enzymatic hydrolysis of langostino shell chitin with mixtures of enzymes from bacterial and fungal sources. Carbohydr Res. 2003 Sep 1; 338(18):1823-33.
  View in: PubMed
 
14. Kournikakis B, Mandeville R, Brousseau P, Ostroff G. Anthrax-protective effects of yeast beta 1,3 glucans. MedGenMed. 2003 Mar 21; 5(1):1.
  View in: PubMed
 
15. Niederman R, Kelderman H, Socransky S, Ostroff G, Genco C, Kent R, Stashenko P. Enhanced neutrophil emigration and Porphyromonas gingivalis reduction following PGG-glucan treatment of mice. Arch Oral Biol. 2002 Aug; 47(8):613-8.
  View in: PubMed
 
16. Bell S, Goldman VM, Bistrian BR, Arnold AH, Ostroff G, Forse RA. Effect of beta-glucan from oats and yeast on serum lipids. Crit Rev Food Sci Nutr. 1999 Mar; 39(2):189-202.
  View in: PubMed
 
17. Stashenko P, Wang CY, Riley E, Wu Y, Ostroff G, Niederman R. Reduction of infection-stimulated periapical bone resorption by the biological response modifier PGG glucan. J Dent Res. 1995 Jan; 74(1):323-30.
  View in: PubMed
 
18. Onderdonk AB, Cisneros RL, Hinkson P, Ostroff G. Anti-infective effect of poly-beta 1-6-glucotriosyl-beta 1-3-glucopyranose glucan in vivo. Infect Immun. 1992 Apr; 60(4):1642-7.
  View in: PubMed
 
19. Simon ES, Toone EJ, Ostroff G, Bednarski MD, Whitesides GM. Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. Methods Enzymol. 1989; 179:275-87.
  View in: PubMed
 
20. Ostroff GR, Pène JJ. Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis. I. Construction and analysis of B. subtilis clone banks in Escherichia coli. Mol Gen Genet. 1984; 193(2):299-305.
  View in: PubMed
 
21. Ostroff GR, Pène JJ. Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis. II. Transfer of sequences propagated in Escherichia coli to B. subtilis. Mol Gen Genet. 1984; 193(2):306-11.
  View in: PubMed
 
22. Ostroff GR, Pène JJ. Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis: isolation of a spontaneous mutant of Bacillus subtilis with enhanced transformability for Escherichia coli-propagated chimeric plasmid DNA. J Bacteriol. 1983 Nov; 156(2):934-6.
  View in: PubMed
 
23. Lynfield YL, Ostroff G. Psoriatic flora. Arch Dermatol. 1973 Sep; 108(3):424-5.
  View in: PubMed
 
24. Lynfield YL, Ostroff G, Abraham J. Bacteria, skin sterilization, and wound healing in psoriasis. N Y State J Med. 1972 Jun 1; 72(11):1247-50.
  View in: PubMed
 
25. ALLEN EG, OSTROFF G, BOVARNICK MR. Inhibition of the cytochrome reductase activity associated with menigopneumonitis virus by fatty acids derived from infected allantoic fluids. Virology. 1960 Aug; 11:737-52.
  View in: PubMed
 
26. LEVEEN HH, FALK G, OSTROFF G, CALEM WS. The production of ulcerative colitis by anticolon sera. Surg Forum. 1960; 11:3-5.
  View in: PubMed
 
27. OSTROFF G, AXELROD DR, BOVARNICK M. Antigenicity of polymers of glutamyl peptide on humans. Proc Soc Exp Biol Med. 1958 Nov; 99(2):345-7.
  View in: PubMed
 
28. SCHIER WW, ROTH A, OSTROFF G, SCHRIFT MH. Hodgkin's disease and immunity. Am J Med. 1956 Jan; 20(1):94-9.
  View in: PubMed
 
For assistance with using Profiles, please refer to the online tutorials or contact UMMS Help Desk or call 508-856-8643.
 
Keyword
Last Name
Institution
    
 
 
 
Keywords   
beta-Glucans
Glucans
Cell Wall
Saccharomyces cerevisiae
Nanoparticles
See all (171) keywords
Co-Authors  
Czech, Michael
Huang, Haibin
Levitz, Stuart
Rice, Peter
Specht, Charles
See all (10) people
Physical Neighbors  
Morel, Caroline
Strambio De Castillia, Caterina
Zapp, Maria
Aouadi, Myriam
Watanabe, Shinya

UMMS Home

Intranet

This is an official Page/Publication of the University of Massachusetts Worcester Campus
Office of the Vice Provost for Research, 55 Lake Ave North, Worcester, Massachusetts 01655
Questions or Comments? Email: publicaffairs@umassmed.edu Phone: 508-856-1572