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1.
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Usmani GN, Woda BA, Newburger PE. Advances in understanding the pathogenesis of HLH. Br J Haematol. 2013 Jun; 161(5):609-22.
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2.
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Gazda HT, Preti M, Sheen MR, O'Donohue MF, Vlachos A, Davies SM, Kattamis A, Doherty L, Landowski M, Buros C, Ghazvinian R, Sieff CA, Newburger PE, Niewiadomska E, Matysiak M, Glader B, Atsidaftos E, Lipton JM, Gleizes PE, Beggs AH. Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia. Hum Mutat. 2012 Jul; 33(7):1037-44.
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3.
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de Oliveira-Junior EB, Bustamante J, Newburger PE, Condino-Neto A. The human NADPH oxidase: primary and secondary defects impairing the respiratory burst function and the microbicidal ability of phagocytes. Scand J Immunol. 2011 May; 73(5):420-7.
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4.
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Bustamante J, Arias AA, Vogt G, Picard C, Galicia LB, Prando C, Grant AV, Marchal CC, Hubeau M, Chapgier A, de Beaucoudrey L, Puel A, Feinberg J, Valinetz E, Jannière L, Besse C, Boland A, Brisseau JM, Blanche S, Lortholary O, Fieschi C, Emile JF, Boisson-Dupuis S, Al-Muhsen S, Woda B, Newburger PE, Condino-Neto A, Dinauer MC, Abel L, Casanova JL. Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nat Immunol. 2011 Mar; 12(3):213-21.
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5.
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Chang TY, Jaffray J, Woda B, Newburger PE, Usmani GN. Hemophagocytic lymphohistiocytosis with MUNC13-4 gene mutation or reduced natural killer cell function prior to onset of childhood leukemia. Pediatr Blood Cancer. 2011 May; 56(5):856-8.
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6.
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Newburger PE, Pindyck TN, Zhu Z, Bolyard AA, Aprikyan AA, Dale DC, Smith GD, Boxer LA. Cyclic neutropenia and severe congenital neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying genes. Pediatr Blood Cancer. 2010 Aug; 55(2):314-7.
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7.
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Li JM, Newburger PE, Gounis MJ, Dargon P, Zhang X, Messina LM. Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model. Gene Ther. 2010 Oct; 17(10):1279-87.
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8.
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Rosenberg PS, Zeidler C, Bolyard AA, Alter BP, Bonilla MA, Boxer LA, Dror Y, Kinsey S, Link DC, Newburger PE, Shimamura A, Welte K, Dale DC. Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy. Br J Haematol. 2010 Jul; 150(2):196-9.
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9.
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Yasukochi Y, Maruyama O, Mahajan MC, Padden C, Euskirchen GM, Schulz V, Hirakawa H, Kuhara S, Pan XH, Newburger PE, Snyder M, Weissman SM. X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3704-9.
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10.
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Doherty L, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Clinton C, Schneider HE, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Glader B, Arceci RJ, Farrar JE, Atsidaftos E, Lipton JM, Gleizes PE, Gazda HT. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2010 Feb 12; 86(2):222-8.
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11.
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Errante PR, Prando C, Bustamante J, Aragão Filho WC, Pereira PV, Rehder J, Casanova JL, Newburger P, Condino Neto A. Comment on "Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency". J Immunol. 2009 Sep 15; 183(6):3559.
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12.
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Mahajan MC, Karmakar S, Newburger PE, Krause DS, Weissman SM. Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture. Exp Hematol. 2009 Oct; 37(10):1143-1156.e3.
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13.
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Rao VK, Price S, Perkins K, Aldridge P, Tretler J, Davis J, Dale JK, Gill F, Hartman KR, Stork LC, Gnarra DJ, Krishnamurti L, Newburger PE, Puck J, Fleisher T. Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS). Pediatr Blood Cancer. 2009 Jul; 52(7):847-52.
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14.
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Newburger PE. Cyclic neutropenia in animals. Am J Hematol. 2009 Apr; 84(4):258; author reply 258.
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15.
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Zhang X, Lian Z, Padden C, Gerstein MB, Rozowsky J, Snyder M, Gingeras TR, Kapranov P, Weissman SM, Newburger PE. A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster. Blood. 2009 Mar 12; 113(11):2526-34.
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16.
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Gazda HT, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Schneider H, Darras N, Hasman C, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Zaucha JM, Glader B, Niemeyer C, Meerpohl JJ, Atsidaftos E, Lipton JM, Gleizes PE, Beggs AH. Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients. Am J Hum Genet. 2008 Dec; 83(6):769-80.
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17.
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Wang JP, Bowen GN, Padden C, Cerny A, Finberg RW, Newburger PE, Kurt-Jones EA. Toll-like receptor-mediated activation of neutrophils by influenza A virus. Blood. 2008 Sep 1; 112(5):2028-34.
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18.
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Luengo-Blanco M, Prando C, Bustamante J, Aragão-Filho WC, Pereira PV, Rehder J, Padden C, Casanova JL, Newburger PE, Condino-Neto A. Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes. Blood. 2008 Aug 15; 112(4):1453-60.
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19.
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Newburger PE, Castle VP. The American Society of Pediatric Hematology/Oncology distinguished career award goes to Laurence A. Boxer, MD. Pediatr Blood Cancer. 2008 Jun; 50(6):1121-2.
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20.
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Newburger PE. IL6 to the rescue. Blood. 2008 Apr 15; 111(8):3914-5.
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21.
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Hochberg JC, Miron PM, Hay BN, Woda BA, Wang SA, Richert-Przygonska M, Aprikyan AA, Newburger PE. Mosaic tetraploidy and transient GFI1 mutation in a patient with severe chronic neutropenia. Pediatr Blood Cancer. 2008 Mar; 50(3):630-2.
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22.
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Marçal LE, Dias-da-Motta PM, Rehder J, Mamoni RL, Blotta MH, Whitney CB, Newburger PE, Costa FF, Saad ST, Condino-Neto A. Up-regulation of NADPH oxidase components and increased production of interferon-gamma by leukocytes from sickle cell disease patients. Am J Hematol. 2008 Jan; 83(1):41-5.
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23.
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Rosenberg PS, Alter BP, Link DC, Stein S, Rodger E, Bolyard AA, Aprikyan AA, Bonilla MA, Dror Y, Kannourakis G, Newburger PE, Boxer LA, Dale DC. Neutrophil elastase mutations and risk of leukaemia in severe congenital neutropenia. Br J Haematol. 2008 Jan; 140(2):210-3.
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24.
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Boxer LA, Newburger PE. A molecular classification of congenital neutropenia syndromes. Pediatr Blood Cancer. 2007 Oct 15; 49(5):609-14.
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25.
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007 Jun 14; 447(7146):799-816.
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26.
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Li JM, Zhang X, Nelson PR, Odgren PR, Nelson JD, Vasiliu C, Park J, Morris M, Lian J, Cutler BS, Newburger PE. Temporal evolution of gene expression in rat carotid artery following balloon angioplasty. J Cell Biochem. 2007 May 15; 101(2):399-410.
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27.
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Hattori H, Zhang X, Jia Y, Subramanian KK, Jo H, Loison F, Newburger PE, Luo HR. RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells. Blood. 2007 Jul 15; 110(2):640-50.
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28.
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Nakayama Y, Stabach P, Maher SE, Mahajan MC, Masiar P, Liao C, Zhang X, Ye ZJ, Tuck D, Bothwell AL, Newburger PE, Weissman SM. A limited number of genes are involved in the differentiation of germinal center B cells. J Cell Biochem. 2006 Dec 1; 99(5):1308-25.
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29.
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Fan L, Jones SN, Padden C, Shen Q, Newburger PE. Nuclease sensitive element binding protein 1 gene disruption results in early embryonic lethality. J Cell Biochem. 2006 Sep 1; 99(1):140-5.
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30.
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Rezk S, Wheelock L, Fletcher JA, Oliveira AM, Keuker CP, Newburger PE, Xu B, Woda BA, Miron PM. Acute lymphocytic leukemia with eosinophilia and unusual karyotype. Leuk Lymphoma. 2006 Jun; 47(6):1176-9.
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31.
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Shen Q, Fan L, Newburger PE. Nuclease sensitive element binding protein 1 associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation. J Cell Physiol. 2006 Jun; 207(3):775-83.
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32.
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Agudelo-Flórez P, Prando-Andrade CC, López JA, Costa-Carvalho BT, Quezada A, Espinosa FJ, de Souza Paiva MA, Roxo P, Grumach A, Jacob CA, Carneiro-Sampaio MM, Newburger PE, Condino-Neto A. Chronic granulomatous disease in Latin American patients: clinical spectrum and molecular genetics. Pediatr Blood Cancer. 2006 Feb; 46(2):243-52.
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33.
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Rozowsky J, Wu J, Lian Z, Nagalakshmi U, Korbel JO, Kapranov P, Zheng D, Dyke S, Newburger P, Miller P, Gingeras TR, Weissman S, Gerstein M, Snyder M. Novel transcribed regions in the human genome. Cold Spring Harb Symp Quant Biol. 2006; 71:111-6.
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34.
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Newburger PE. Disorders of neutrophil number and function. Hematology Am Soc Hematol Educ Program. 2006; 104-10.
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35.
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Almeida AC, Rehder J, Severino SD, Martins-Filho J, Newburger PE, Condino-Neto A. The effect of IFN-gamma and TNF-alpha on the NADPH oxidase system of human colostrum macrophages, blood monocytes, and THP-1 cells. J Interferon Cytokine Res. 2005 Sep; 25(9):540-6.
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36.
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Newburger PE. Hematology and oncology. Curr Opin Pediatr. 2005 Feb; 17(1):1-2.
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37.
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Kurt-Jones EA, Belko J, Yu C, Newburger PE, Wang J, Chan M, Knipe DM, Finberg RW. The role of toll-like receptors in herpes simplex infection in neonates. J Infect Dis. 2005 Mar 1; 191(5):746-8.
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38.
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Kluger Y, Lian Z, Zhang X, Newburger PE, Weissman SM. A panorama of lineage-specific transcription in hematopoiesis. Bioessays. 2004 Dec; 26(12):1276-87.
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39.
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Marçal LE, Rehder J, Newburger PE, Condino-Neto A. Superoxide release and cellular gluthatione peroxidase activity in leukocytes from children with persistent asthma. Braz J Med Biol Res. 2004 Nov; 37(11):1607-13.
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40.
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Zhan Y, He D, Newburger PE, Zhou GW. p47(phox) PX domain of NADPH oxidase targets cell membrane via moesin-mediated association with the actin cytoskeleton. J Cell Biochem. 2004 Jul 1; 92(4):795-809.
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41.
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Kluger Y, Tuck DP, Chang JT, Nakayama Y, Poddar R, Kohya N, Lian Z, Ben Nasr A, Halaban HR, Krause DS, Zhang X, Newburger PE, Weissman SM. Lineage specificity of gene expression patterns. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6508-13.
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42.
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Agudelo-Flórez P, Costa-Carvalho BT, López JA, Redher J, Newburger PE, Olalla-Saad ST, Condino-Neto A. Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections. Am J Hematol. 2004 Mar; 75(3):151-6.
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43.
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Newburger PE. Hematology and oncology. Curr Opin Pediatr. 2004 Feb; 16(1):1-2.
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44.
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Lopez JA, Newburger PE, Condino-Neto A. The effect of IFN-gamma and TNF-alpha on the eosinophilic differentiation and NADPH oxidase activation of human HL-60 clone 15 cells. J Interferon Cytokine Res. 2003 Dec; 23(12):737-44.
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45.
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Zhang X, Kluger Y, Nakayama Y, Poddar R, Whitney C, DeTora A, Weissman SM, Newburger PE. Gene expression in mature neutrophils: early responses to inflammatory stimuli. J Leukoc Biol. 2004 Feb; 75(2):358-72.
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46.
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Wallace J, Zhou Y, Usmani GN, Reardon M, Newburger P, Woda B, Pihan G. BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays. Leukemia. 2003 Jul; 17(7):1404-10.
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47.
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Wallace J, Zhou Y, Usmani GN, Reardon M, Newburger P, Woda B, Pihan G. BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays. Leukemia. 2003 Jul; 17(7):1411-3.
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48.
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Tsukahara Y, Lian Z, Zhang X, Whitney C, Kluger Y, Tuck D, Yamaga S, Nakayama Y, Weissman SM, Newburger PE. Gene expression in human neutrophils during activation and priming by bacterial lipopolysaccharide. J Cell Biochem. 2003 Jul 1; 89(4):848-61.
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49.
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Newburger PE. Hematology and oncology. Curr Opin Pediatr. 2003 Feb; 15(1):1-2.
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50.
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Lian Z, Kluger Y, Greenbaum DS, Tuck D, Gerstein M, Berliner N, Weissman SM, Newburger PE. Genomic and proteomic analysis of the myeloid differentiation program: global analysis of gene expression during induced differentiation in the MPRO cell line. Blood. 2002 Nov 1; 100(9):3209-20.
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51.
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Kurt-Jones EA, Mandell L, Whitney C, Padgett A, Gosselin K, Newburger PE, Finberg RW. Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils. Blood. 2002 Sep 1; 100(5):1860-8.
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52.
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Newburger PE, Elfenbein DS, Boxer LA. Adolescents with cancer: access to clinical trials and age-appropriate care. Curr Opin Pediatr. 2002 Feb; 14(1):1-4.
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53.
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Noack D, Heyworth PG, Newburger PE, Cross AR. An unusual intronic mutation in the CYBB gene giving rise to chronic granulomatous disease. Biochim Biophys Acta. 2001 Sep 28; 1537(2):125-31.
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54.
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Lian Z, Wang L, Yamaga S, Bonds W, Beazer-Barclay Y, Kluger Y, Gerstein M, Newburger PE, Berliner N, Weissman SM. Genomic and proteomic analysis of the myeloid differentiation program. Blood. 2001 Aug 1; 98(3):513-24.
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55.
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Subrahmanyam YV, Yamaga S, Prashar Y, Lee HH, Hoe NP, Kluger Y, Gerstein M, Goguen JD, Newburger PE, Weissman SM. RNA expression patterns change dramatically in human neutrophils exposed to bacteria. Blood. 2001 Apr 15; 97(8):2457-68.
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56.
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Noack D, Rae J, Cross AR, Ellis BA, Newburger PE, Curnutte JT, Heyworth PG. Autosomal recessive chronic granulomatous disease caused by defects in NCF-1, the gene encoding the phagocyte p47-phox: mutations not arising in the NCF-1 pseudogenes. Blood. 2001 Jan 1; 97(1):305-11.
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57.
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Condino-Neto A, Newburger PE. Interferon-gamma improves splicing efficiency of CYBB gene transcripts in an interferon-responsive variant of chronic granulomatous disease due to a splice site consensus region mutation. Blood. 2000 Jun 1; 95(11):3548-54.
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58.
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Wu R, Shen Q, Newburger PE. Recognition and binding of the human selenocysteine insertion sequence by nucleolin. J Cell Biochem. 2000 Apr; 77(3):507-16.
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59.
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Newburger PE, Subrahmanyam YV, Weissman SM. Global analysis of neutrophil gene expression. Curr Opin Hematol. 2000 Jan; 7(1):16-20.
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60.
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Newburger PE. Hematology and oncology. Curr Opin Pediatr. 1999 Feb; 11(1):31-2.
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61.
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Subrahmanyam YV, Baskaran N, Newburger PE, Weissman SM. A modified method for the display of 3'-end restriction fragments of cDNAs: molecular profiling of gene expression in neutrophils. Methods Enzymol. 1999; 303:272-97.
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62.
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Condino-Neto A, Newburger PE. NADPH oxidase activity and cytochrome b558 content of human Epstein-Barr-virus-transformed B lymphocytes correlate with expression of genes encoding components of the oxidase system. Arch Biochem Biophys. 1998 Dec 15; 360(2):158-64.
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63.
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Cooper CL, Newburger PE. Differential expression of Id genes in multipotent myeloid progenitor cells: Id-1 is induced by early-and late-acting cytokines while Id-2 is selectively induced by cytokines that drive terminal granulocytic differentiation. J Cell Biochem. 1998 Nov 1; 71(2):277-85.
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64.
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Condino-Neto A, Whitney C, Newburger PE. Dexamethasone but not indomethacin inhibits human phagocyte nicotinamide adenine dinucleotide phosphate oxidase activity by down-regulating expression of genes encoding oxidase components. J Immunol. 1998 Nov 1; 161(9):4960-7.
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65.
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Rae J, Newburger PE, Dinauer MC, Noack D, Hopkins PJ, Kuruto R, Curnutte JT. X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase. Am J Hum Genet. 1998 Jun; 62(6):1320-31.
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66.
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Inanami O, Johnson JL, McAdara JK, Benna JE, Faust LR, Newburger PE, Babior BM. Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304. J Biol Chem. 1998 Apr 17; 273(16):9539-43.
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67.
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Shen Q, Wu R, Leonard JL, Newburger PE. Identification and molecular cloning of a human selenocysteine insertion sequence-binding protein. A bifunctional role for DNA-binding protein B. J Biol Chem. 1998 Mar 6; 273(10):5443-6.
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68.
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Newburger PE. Hematology and oncology. Curr Opin Pediatr. 1998 Feb; 10(1):47-8.
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69.
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Becker PS, Li Z, Potselueva T, Madri JA, Newburger PE, Berliner N. Laminin promotes differentiation of NB4 promyelocytic leukemia cells with all-trans retinoic acid. Blood. 1996 Jul 1; 88(1):261-7.
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70.
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Leonard JL, Leonard DM, Shen Q, Farwell AP, Newburger PE. Selenium-regulated translation control of heterologous gene expression: normal function of selenocysteine-substituted gene products. J Cell Biochem. 1996 Jun 1; 61(3):410-9.
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71.
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Quesenberry PJ, Iscove NN, Cooper C, Brady G, Newburger PE, Stein GS, Stein JS, Reddy GP, Pearson-White S. Expression of basic helix-loop-helix transcription factors in explant hematopoietic progenitors. J Cell Biochem. 1996 Jun 1; 61(3):478-88.
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72.
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Chanock SJ, Faust LR, Barrett D, Christensen B, Newburger PE, Babior BM. Partial reconstitution of the respiratory burst oxidase in lymphoblastoid B cell lines lacking p67-phox after transfection with an expression vector containing wild-type and mutant p67 -phox cDNAs: Deletions of the carboxy and amino terminal residues of p67-phox are not required for activity. Exp Hematol. 1996 Mar; 24(4):531-6.
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73.
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Newburger PE, Quesenberry PJ. Umbilical cord blood as a new and promising source of unrelated-donor hematopoietic stem cells for transplantation. Curr Opin Pediatr. 1996 Feb; 8(1):29-32.
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74.
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Shen Q, McQuilkin PA, Newburger PE. RNA-binding proteins that specifically recognize the selenocysteine insertion sequence of human cellular glutathione peroxidase mRNA. J Biol Chem. 1995 Dec 22; 270(51):30448-52.
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75.
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Shen Q, Leonard JL, Newburger PE. Structure and function of the selenium translation element in the 3'-untranslated region of human cellular glutathione peroxidase mRNA. RNA. 1995 Jul; 1(5):519-25.
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76.
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Woodman RC, Newburger PE, Anklesaria P, Erickson RW, Rae J, Cohen MS, Curnutte JT. A new X-linked variant of chronic granulomatous disease characterized by the existence of a normal clone of respiratory burst-competent phagocytic cells. Blood. 1995 Jan 1; 85(1):231-41.
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77.
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Newburger PE, Malawista SE, Dinauer MC, Gelbart T, Woodman RC, Chada S, Shen Q, van Blaricom G, Quie PG, Curnutte JT. Chronic granulomatous disease and glutathione peroxidase deficiency, revisited. Blood. 1994 Dec 1; 84(11):3861-9.
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78.
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Shen Q, Chada S, Whitney C, Newburger PE. Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation. Blood. 1994 Dec 1; 84(11):3902-8.
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79.
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Newburger PE, Skalnik DG, Hopkins PJ, Eklund EA, Curnutte JT. Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558. J Clin Invest. 1994 Sep; 94(3):1205-11.
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80.
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Shen Q, Townes PL, Padden C, Newburger PE. An in-frame trinucleotide repeat in the coding region of the human cellular glutathione peroxidase (GPX1) gene: in vivo polymorphism and in vitro instability. Genomics. 1994 Sep 1; 23(1):292-4.
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81.
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Maly FE, Schuerer-Maly CC, Quilliam L, Cochrane CG, Newburger PE, Curnutte JT, Gifford M, Dinauer MC. Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA. J Exp Med. 1993 Dec 1; 178(6):2047-53.
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82.
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Baker RD, Baker SS, LaRosa K, Whitney C, Newburger PE. Selenium regulation of glutathione peroxidase in human hepatoma cell line Hep3B. Arch Biochem Biophys. 1993 Jul; 304(1):53-7.
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83.
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Bernardo J, Brennan L, Brink HF, Ortiz MF, Newburger PE, Simons ER. Chemotactic peptide-induced cytoplasmic pH changes in incubated human monocytes. J Leukoc Biol. 1993 Jun; 53(6):673-8.
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84.
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Shen Q, Chu FF, Newburger PE. Sequences in the 3'-untranslated region of the human cellular glutathione peroxidase gene are necessary and sufficient for selenocysteine incorporation at the UGA codon. J Biol Chem. 1993 May 25; 268(15):11463-9.
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85.
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Pise CA, Newburger PE, Holland CA. Human immunodeficiency virus type 1-infected HL-60 cells are capable of both monocytic and granulocytic differentiation. J Gen Virol. 1992 Dec; 73 ( Pt 12):3257-61.
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86.
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Chanock SJ, Faust LR, Barrett D, Bizal C, Maly FE, Newburger PE, Ruedi JM, Smith RM, Babior BM. O2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA. Proc Natl Acad Sci U S A. 1992 Nov 1; 89(21):10174-7.
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87.
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Schapiro BL, Newburger PE, Klempner MS, Dinauer MC. Chronic granulomatous disease presenting in a 69-year-old man. N Engl J Med. 1991 Dec 19; 325(25):1786-90.
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88.
|
Newburger PE, Dai Q, Whitney C. In vitro regulation of human phagocyte cytochrome b heavy and light chain gene expression by bacterial lipopolysaccharide and recombinant human cytokines. J Biol Chem. 1991 Aug 25; 266(24):16171-7.
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89.
|
Ezekowitz RA, Sieff CA, Dinauer MC, Nathan DG, Orkin SH, Newburger PE. Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell. Blood. 1990 Dec 15; 76(12):2443-8.
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90.
|
Ryan TC, Weil GJ, Newburger PE, Haugland R, Simons ER. Measurement of superoxide release in the phagovacuoles of immune complex-stimulated human neutrophils. J Immunol Methods. 1990 Jul 3; 130(2):223-33.
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91.
|
Bernardo J, Newburger PE, Brennan L, Brink HF, Bresnick SA, Weil G, Simons ER. Simultaneous flow cytometric measurements of cytoplasmic Ca++ and membrane potential changes upon FMLP exposure as HL-60 cells mature into granulocytes: using [Ca++]in as an indicator of granulocyte maturity. J Leukoc Biol. 1990 Mar; 47(3):265-74.
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92.
|
Chada S, Le Beau MM, Casey L, Newburger PE. Isolation and chromosomal localization of the human glutathione peroxidase gene. Genomics. 1990 Feb; 6(2):268-71.
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93.
|
Barker KA, Newburger PE. Relationships between the cell cycle and the expression of c-myc and transferrin receptor genes during induced myeloid differentiation. Exp Cell Res. 1990 Jan; 186(1):1-5.
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94.
|
Chada S, Whitney C, Newburger PE. Post-transcriptional regulation of glutathione peroxidase gene expression by selenium in the HL-60 human myeloid cell line. Blood. 1989 Nov 15; 74(7):2535-41.
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95.
|
Holland CA, Chada S, Wright J, Whitney C, Harigaya K, Greenberger JS, Newburger PE. Differentiation of human hematopoietic cells increases expression of a gene transferred by a retroviral vector. J Leukoc Biol. 1989 Sep; 46(3):221-9.
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96.
|
Holland CA, Rothstein L, Sakakeeny MA, Anklesaria P, Griffin JD, Harigaya K, Newburger PE, Greenberger JS. Infection of hematopoietic and stromal cells in human continuous bone marrow cultures by a retroviral vector containing the neomycin resistance gene. Acta Haematol. 1989; 82(3):136-43.
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97.
|
Ezekowitz RA, Newburger PE. New perspectives in chronic granulomatous disease. J Clin Immunol. 1988 Nov; 8(6):419-25.
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98.
|
Ezekowitz RA, Dinauer MC, Jaffe HS, Orkin SH, Newburger PE. Partial correction of the phagocyte defect in patients with X-linked chronic granulomatous disease by subcutaneous interferon gamma. N Engl J Med. 1988 Jul 21; 319(3):146-51.
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99.
|
Newburger PE, Ezekowitz RA, Whitney C, Wright J, Orkin SH. Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5215-9.
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100.
|
Barker KA, Orkin SH, Newburger PE. Expression of the X-CGD gene during induced differentiation of myeloid leukemia cell line HL-60. Mol Cell Biol. 1988 Jul; 8(7):2804-10.
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101.
|
Newburger PE, Ezekowitz RA. Cellular and molecular effects of recombinant interferon gamma in chronic granulomatous disease. Hematol Oncol Clin North Am. 1988 Jun; 2(2):267-76.
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102.
|
Nitzberg MC, Newburger PE, Raymond J. Marrow donors and international cooperation. Lancet. 1988 Jan 16; 1(8577):117-8.
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103.
|
Ezekowitz RA, Orkin SH, Newburger PE. Recombinant interferon gamma augments phagocyte superoxide production and X-chronic granulomatous disease gene expression in X-linked variant chronic granulomatous disease. J Clin Invest. 1987 Oct; 80(4):1009-16.
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104.
|
Rothenberg ME, Caulfield JP, Austen KF, Hein A, Edmiston K, Newburger PE, Stevens RL. Biochemical and morphological characterization of basophilic leukocytes from two patients with myelogenous leukemia. J Immunol. 1987 Apr 15; 138(8):2616-25.
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105.
|
Speier C, Newburger PE. Changes in superoxide dismutase, catalase, and the glutathione cycle during induced myeloid differentiation. Arch Biochem Biophys. 1986 Dec; 251(2):551-7.
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106.
|
Beard CJ, Key L, Newburger PE, Ezekowitz RA, Arceci R, Miller B, Proto P, Ryan T, Anast C, Simons ER. Neutrophil defect associated with malignant infantile osteopetrosis. J Lab Clin Med. 1986 Nov; 108(5):498-505.
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107.
|
Newburger PE, Luscinskas FW, Ryan T, Beard CJ, Wright J, Platt OS, Simons ER, Tauber AI. Variant chronic granulomatous disease: modulation of the neutrophil defect by severe infection. Blood. 1986 Oct; 68(4):914-9.
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108.
|
Royer-Pokora B, Kunkel LM, Monaco AP, Goff SC, Newburger PE, Baehner RL, Cole FS, Curnutte JT, Orkin SH. Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location. Nature. 1986 Jul 3-9; 322(6074):32-8.
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109.
|
Kazazian HH, Orkin SH, Boehm CD, Goff SC, Wong C, Dowling CE, Newburger PE, Knowlton RG, Brown V, Donis-Keller H. Characterization of a spontaneous mutation to a beta-thalassemia allele. Am J Hum Genet. 1986 Jun; 38(6):860-7.
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110.
|
Takahashi K, Newburger PE, Cohen HJ. Glutathione peroxidase protein. Absence in selenium deficiency states and correlation with enzymatic activity. J Clin Invest. 1986 Apr; 77(4):1402-4.
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111.
|
Greenberger JS, FitzGerald TJ, Rothstein L, Pierce J, Sakakeeny MA, Weichselbaum RR, Naparstek E, Newburger P, Griffin J, Bast R, et al. Long-term culture of human granulocytes and granulocyte progenitor cells. Prog Clin Biol Res. 1986; 211:159-85.
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112.
|
Royer-Pokora B, Kunkel LM, Monaco AP, Goff SC, Newburger PE, Baehner RL, Cole FS, Curnutte JT, Orkin SH. Cloning the gene for the inherited disorder chronic granulomatous disease on the basis of its chromosomal location. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 1:177-83.
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113.
|
Clegg HW, Ephros M, Newburger PE. Pseudomonas cepacia pneumonia in chronic granulomatous disease. Pediatr Infect Dis. 1986 Jan-Feb; 5(1):111.
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114.
|
Speier C, Baker SS, Newburger PE. Relationships between in vitro selenium supply, glutathione peroxidase activity, and phagocytic function in the HL-60 human myeloid cell line. J Biol Chem. 1985 Jul 25; 260(15):8951-5.
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115.
|
Leb L, Beatson P, Fortier N, Newburger PE, Snyder LM. Modulation of mononuclear phagocyte cytotoxicity by alpha-tocopherol (vitamin E). J Leukoc Biol. 1985 Apr; 37(4):449-59.
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116.
|
Newburger PE, Speier C, Stock JL, Perrine SP, Greenberger JS. Chediak-Higashi syndrome: studies in long-term bone marrow culture. Exp Hematol. 1985 Feb; 13(2):117-22.
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117.
|
Newburger PE, Speier C, Borregaard N, Walsh CE, Whitin JC, Simons ER. Development of the superoxide-generating system during differentiation of the HL-60 human promyelocytic leukemia cell line. J Biol Chem. 1984 Mar 25; 259(6):3771-6.
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118.
|
Szymanski IO, Teno RA, Gandhi JG, Newburger PE. Studies on low-dose hydroxyethyl starch leukapheresis. Rate of elimination of HES in vivo and function of the harvested granulocytes in vitro. Vox Sang. 1984; 47(5):325-9.
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119.
|
Shurin SB, Cohen HJ, Whitin JC, Newburger PE. Impaired granulocyte superoxide production and prolongation of the respiratory burst due to a low-affinity NADPH-dependent oxidase. Blood. 1983 Sep; 62(3):564-71.
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120.
|
Newburger PE, Robinson JM, Pryzwansky KB, Rosoff PM, Greenberger JS, Tauber AI. Human neutrophil dysfunction with giant granules and defective activation of the respiratory burst. Blood. 1983 Jun; 61(6):1247-57.
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121.
|
Seger RA, Tiefenauer L, Matsunaga T, Wildfeuer A, Newburger PE. Chronic granulomatous disease due to granulocytes with abnormal NADPH oxidase activity and deficient cytochrome-b. Blood. 1983 Mar; 61(3):423-8.
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122.
|
Newburger PE, Novak TJ, McCaffrey RP. Eosinophilic cytoplasmic inclusions in fetal leukocytes: are Auer bodies a recapitulation of fetal morphology? Blood. 1983 Mar; 61(3):593-5.
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123.
|
Rappeport JM, Newburger PE, Goldblum RM, Goldman AS, Nathan DG, Parkman R. Allogeneic bone marrow transplantation for chronic granulomatous disease. J Pediatr. 1982 Dec; 101(6):952-5.
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124.
|
Cohen HJ, Chovaniec ME, Wilson MK, Newburger PE. Con-A-stimulated superoxide production by granulocytes: reversible activation of NADPH oxidase. Blood. 1982 Nov; 60(5):1188-94.
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125.
|
Newburger PE, Tauber AI. Heterogeneous pathways of oxidizing radical production in human neutrophils and the HL-60 cell line. Pediatr Res. 1982 Oct; 16(10):856-60.
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126.
|
Newburger PE. Superoxide generation by human fetal granulocytes. Pediatr Res. 1982 May; 16(5):373-6.
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127.
|
Cohen HJ, Newburger PE, Chovaniec ME, Whitin JC, Simons ER. Opsonized zymosan-stimulated granulocytes-activation and activity of the superoxide-generating system and membrane potential changes. Blood. 1981 Nov; 58(5):975-82.
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128.
|
Greenberg HM, Newburger PE, Parker LM, Novak T, Greenberger JS. Human granulocytes generated in continuous bone marrow culture are physiologically normal. Blood. 1981 Oct; 58(4):724-32.
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129.
|
Button LN, DeWolf WC, Newburger PE, Jacobson MS, Kevy SV. The effects of irradiation on blood components. Transfusion. 1981 Jul-Aug; 21(4):419-26.
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130.
|
Newburger PE, Baker RD, Hansen SL, Duncan RA, Greenberger JS. Functionally deficient differentiation of HL-60 promyelocytic leukemia cells induced by phorbol myristate acetate. Cancer Res. 1981 May; 41(5):1861-5.
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131.
|
Newburger PE, Latt SA, Pesando JM, Gustashaw K, Powers M, Chaganti RS, O'Reilly RJ. Leukemia relapse in donor cells after allogeneic bone-marrow transplantation. N Engl J Med. 1981 Mar 19; 304(12):712-4.
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132.
|
Newburger PE, Sallan SE. Chronic pain: principles of management. J Pediatr. 1981 Feb; 98(2):180-9.
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133.
|
Greenberg HM, Parker LM, Newburger PE, Said J, Cohen GI, Greenberger JS. Corticosteroid dependence of continuous hemopoiesis in vitro with murine or human bone marrow. Haematol Blood Transfus. 1981; 26:289-93.
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134.
|
Greenberger JS, Newburger PE, Sakakeeny M. Phorbol myristate acetate stimulates macrophage differentiation and replication and alters granulopoiesis and leukemogenesis in long-term bone marrow cultures. Blood. 1980 Sep; 56(3):368-79.
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135.
|
Newburger PE, Kruskall MS, Rappeport JM, Robinson SH, Chovaniec ME, Cohen HJ. Chronic granulomatous disease. Expression of the metabolic defect by in vitro culture of bone marrow progenitors. J Clin Invest. 1980 Sep; 66(3):599-602.
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136.
|
Cohen HJ, Newburger PE, Chovaniec ME. NAD(P)H-dependent superoxide production by phagocytic vesicles from guinea pig and human granulocytes. J Biol Chem. 1980 Jul 25; 255(14):6584-8.
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137.
|
Newburger PE, Pagano JS, Greenberger JS, Karpas A, Cohen HJ. Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line. J Cell Biol. 1980 Jun; 85(3):549-57.
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138.
|
Rappeport JM, Parkman R, Newburger P, Camitta BM, Chusid MJ. Correction of infantile agranulocytosis (Kostmann's syndrome) by allogeneic bone marrow transplantation. Am J Med. 1980 Apr; 68(4):605-9.
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139.
|
Greenberger JS, Newburger PE, Lipton JM, Moloney WC, Sakakeeny MA, Jackson PL. Virus and cell requirements for Friend virus granulocytic leukemogenesis in long-term bone marrow cultures of NIH swiss [N:NIH(S)] mice. J Natl Cancer Inst. 1980 Apr; 64(4):867-78.
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140.
|
Newburger PE, Chovaniec ME, Cohen HJ. Activity and activation of the granulocyte superoxide-generating system. Blood. 1980 Jan; 55(1):85-92.
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141.
|
Newburger PE, Chovaniec ME, Greenberger JS, Cohen HJ. Functional changes in human leukemic cell line HL-60. A model for myeloid differentiation. J Cell Biol. 1979 Aug; 82(2):315-22.
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142.
|
Newburger PE, Latt SA. Improved fluorescent staining of interphase nuclei for prenatal diagnosis. Lancet. 1979 May 26; 1(8126):1144.
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143.
|
Boal DK, Newburger PE, Teele RL. Esophagitis induced by combined radiation and adriamycin. AJR Am J Roentgenol. 1979 Apr; 132(4):567-70.
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144.
|
Newburger PE, Cohen HJ, Rothchild SB, Hobbins JC, Malawista SE, Mahoney MJ. Prenatal diagnosis of chronic granulomatous disease. N Engl J Med. 1979 Jan 25; 300(4):178-81.
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145.
|
Greenberger JS, Newburger PE, Karpas A, Moloney WC. Constitutive and inducible granulocyte-macrophage functions in mouse, rat, and human myeloid leukemia-derived continuous tissue culture lines. Cancer Res. 1978 Oct; 38(10):3340-8.
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146.
|
Newburger PE, Cassady JR, Jaffe N. Esophagitis due to adriamycin and radiation therapy for childhood malignancy. Cancer. 1978 Aug; 42(2):417-23.
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147.
|
Katz DH, Hamaoka T, Newburger PE, Benacerraf B. Hapten-specific IgE antibody responses in mice. IV. Evidence for distinctive sensitivities of IgE and IgG B lymphocytes to the regulatory influence of T cells. J Immunol. 1974 Sep; 113(3):974-83.
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148.
|
Hamaoka T, Newburger PE, Katz DH, Benacerraf B. Hapten-specific IgE antibody responses in mice. 3. Establishment of parameters for generation of helper T cell function regulating the primary and secondary responses of IgE and IgG B lymphocytes. J Immunol. 1974 Sep; 113(3):958-73.
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149.
|
Newburger PE, Hamaoka T, Katz DH. Potentiation of helper T cell function in IgE antibody responses by bacterial lipolysaccharide (LPS). J Immunol. 1974 Sep; 113(3):824-9.
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150.
|
Dorf ME, Newburger PE, Hamaoka T, Katz DH, Benacerraf B. Characterization of an immune response gene in mice controlling IgE and IgM antibody responses to ragweed pollen extract and its 2,4-dinitrophenylated derivative. Eur J Immunol. 1974 May; 4(5):346-9.
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