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1.
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Stein GS, Stein JL, van J Wijnen A, Lian JB, Montecino M, Medina R, Kapinas K, Ghule P, Grandy R, Zaidi SK, Becker KA. The architectural organization of human stem cell cycle regulatory machinery. Curr Pharm Des. 2012 May 1; 18(13):1679-85.
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2.
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Lian JB, Stein GS, van Wijnen AJ, Stein JL, Hassan MQ, Gaur T, Zhang Y. MicroRNA control of bone formation and homeostasis. Nat Rev Endocrinol. 2012 Apr; 8(4):212-27.
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3.
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van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ. Genomic Promoter Occupancy of Runt-related Transcription Factor RUNX2 in Osteosarcoma Cells Identifies Genes Involved in Cell Adhesion and Motility. J Biol Chem. 2012 Feb 10; 287(7):4503-17.
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4.
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Henriquez B, Hepp M, Merino P, Sepulveda H, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. C/EBPß binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells. J Cell Physiol. 2011 Nov; 226(11):3043-52.
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5.
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Liu JC, Lengner CJ, Gaur T, Lou Y, Hussain S, Jones MD, Borodic B, Colby JL, Steinman HA, van Wijnen AJ, Stein JL, Jones SN, Stein GS, Lian JB. Runx2 protein expression utilizes the runx2 p1 promoter to establish osteoprogenitor cell number for normal bone formation. J Biol Chem. 2011 Aug 26; 286(34):30057-70.
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6.
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Zhang Y, Xie RL, Croce CM, Stein JL, Lian JB, van Wijnen AJ, Stein GS. A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9863-8.
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7.
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Gordon JA, Hassan MQ, Koss M, Montecino M, Selleri L, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Epigenetic Regulation of Early Osteogenesis and Mineralized Tissue Formation by a HOXA10-PBX1-Associated Complex. Cells Tissues Organs. 2011; 194(2-4):146-50.
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8.
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Liu LJ, Xie R, Hussain S, Lian JB, Rivera-Perez J, Jones SN, Stein JL, Stein GS, van Wijnen AJ. Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. Gene. 2011 Sep 1; 483(1-2):1-10.
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9.
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Ghule PN, Medina R, Lengner CJ, Mandeville M, Qiao M, Dominski Z, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Reprogramming the pluripotent cell cycle: Restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells. J Cell Physiol. 2011 May; 226(5):1149-56.
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10.
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Pockwinse SM, Kota KP, Quaresma AJ, Imbalzano AN, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Nickerson JA. Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression. J Cell Physiol. 2011 May; 226(5):1383-9.
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11.
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Zaidi SK, Young DW, Montecino M, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Bookmarking the genome: maintenance of epigenetic information. J Biol Chem. 2011 May 27; 286(21):18355-61.
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12.
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Stein GS, Stein JL, van Wijnen AJ, Lian JB, Zaidi SK, Nickerson JA, Montecino MA, Young DW. An architectural genetic and epigenetic perspective. Integr Biol (Camb). 2011 Apr 1; 3(4):297-303.
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13.
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Pratap J, Akech J, Wixted JJ, Szabo G, Hussain S, McGee-Lawrence ME, Li X, Bedard K, Dhillon RJ, van Wijnen AJ, Stein JL, Stein GS, Westendorf JJ, Lian JB. The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss. Mol Cancer Ther. 2010 Dec; 9(12):3210-20.
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14.
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Bakshi R, Hassan MQ, Pratap J, Lian JB, Montecino MA, van Wijnen AJ, Stein JL, Imbalzano AN, Stein GS. The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes. J Cell Physiol. 2010 Nov; 225(2):569-76.
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15.
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Hassan MQ, Gordon JA, Beloti MM, Croce CM, van Wijnen AJ, Stein JL, Stein GS, Lian JB. A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19879-84.
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16.
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Zaidi SK, Young DW, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information. Mol Cell Biol. 2010 Oct; 30(20):4758-66.
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17.
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Zaidi SK, Young DW, Montecino MA, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Mitotic bookmarking of genes: a novel dimension to epigenetic control. Nat Rev Genet. 2010 Aug; 11(8):583-9.
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18.
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Hassan MQ, Gordon JA, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets. J Cell Biochem. 2010 Jul 1; 110(4):817-22.
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19.
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Kurek KC, Del Mare S, Salah Z, Abdeen S, Sadiq H, Lee SH, Gaudio E, Zanesi N, Jones KB, DeYoung B, Amir G, Gebhardt M, Warman M, Stein GS, Stein JL, Lian JB, Aqeilan RI. Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression. Cancer Res. 2010 Jul 1; 70(13):5577-86.
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20.
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Qiao M, Wang Y, Xu X, Lu J, Dong Y, Tao W, Stein J, Stein GS, Iglehart JD, Shi Q, Pardee AB. Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis. Mol Cell. 2010 May 28; 38(4):512-23.
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21.
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Gordon JA, Hassan MQ, Saini S, Montecino M, van Wijnen AJ, Stein GS, Stein JL, Lian JB. Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors. Mol Cell Biol. 2010 Jul; 30(14):3531-41.
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22.
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Han MS, Kim HJ, Wee HJ, Lim KE, Park NR, Bae SC, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Choi JY. The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta. J Cell Biochem. 2010 May; 110(1):97-103.
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23.
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Jeong JH, Jung YK, Kim HJ, Jin JS, Kim HN, Kang SM, Kim SY, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Kato S, Choi JY. The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues. Mol Cell Biol. 2010 May; 30(10):2365-75.
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24.
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van der Deen M, Akech J, Wang T, FitzGerald TJ, Altieri DC, Languino LR, Lian JB, van Wijnen AJ, Stein JL, Stein GS. The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells. J Cell Biochem. 2010 Mar 1; 109(4):828-37.
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25.
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Arriagada G, Henriquez B, Moena D, Merino P, Ruiz-Tagle C, Lian JB, Stein GS, Stein JL, Montecino M. Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts. J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2):156-8.
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26.
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Ali SA, Zaidi SK, Dobson JR, Shakoori AR, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes. Proc Natl Acad Sci U S A. 2010 Mar 2; 107(9):4165-9.
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27.
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Arriagada G, Paredes R, van Wijnen AJ, Lian JB, van Zundert B, Stein GS, Stein JL, Montecino M. 1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA. J Cell Physiol. 2010 Feb; 222(2):336-46.
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28.
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Becker KA, Ghule PN, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells. J Cell Physiol. 2010 Feb; 222(2):456-64.
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29.
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Gaur T, Hussain S, Mudhasani R, Parulkar I, Colby JL, Frederick D, Kream BE, van Wijnen AJ, Stein JL, Stein GS, Jones SN, Lian JB. Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse. Dev Biol. 2010 Apr 1; 340(1):10-21.
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30.
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Becker KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming. J Cell Physiol. 2010 Jan; 222(1):103-10.
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31.
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Stein G, van Wijnen AJ, Imbalzano AN, Montecino M, Zaidi S, Lian JB, Nickerson JA, Stein JL. Architectural Genetic and Epigenetic Control of Regulatory Networks: Compartmentalizing Machinery for Transcription and chromatin remodeling in nuclear Microenvironments. Crit Rev Eukaryot Gene Expr. 2010; 20(2):149-55.
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32.
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Zaidi SK, Medina RF, Pockwinse SM, Bakshi R, Kota KP, Ali SA, Young DW, Nickerson JA, Javed A, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Subnuclear localization and intranuclear trafficking of transcription factors. Methods Mol Biol. 2010; 647:77-93.
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33.
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Dowdy CR, Xie R, Frederick D, Hussain S, Zaidi SK, Vradii D, Javed A, Li X, Jones SN, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation. Hum Mol Genet. 2010 Mar 15; 19(6):1048-57.
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34.
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San Martin IA, Varela N, Gaete M, Villegas K, Osorio M, Tapia JC, Antonelli M, Mancilla EE, Pereira BP, Nathan SS, Lian JB, Stein JL, Stein GS, van Wijnen AJ, Galindo M. Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells. J Cell Physiol. 2009 Dec; 221(3):560-71.
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35.
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Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB. Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene. 2010 Feb 11; 29(6):811-21.
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36.
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Stein GS, Stein JL, Van Wijnen AJ, Lian JB, Montecino M, Croce CM, Choi JY, Ali SA, Pande S, Hassan MQ, Zaidi SK, Young DW. Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer. Adv Enzyme Regul. 2010; 50(1):160-7.
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37.
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Zhang Y, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells. J Cell Biochem. 2009 Oct 15; 108(3):651-9.
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38.
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Zaidi SK, Dowdy CR, van Wijnen AJ, Lian JB, Raza A, Stein JL, Croce CM, Stein GS. Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network. Cancer Res. 2009 Nov 1; 69(21):8249-55.
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39.
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Filion TM, Qiao M, Ghule PN, Mandeville M, van Wijnen AJ, Stein JL, Lian JB, Altieri DC, Stein GS. Survival responses of human embryonic stem cells to DNA damage. J Cell Physiol. 2009 Sep; 220(3):586-92.
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40.
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Pratap J, Imbalzano KM, Underwood JM, Cohet N, Gokul K, Akech J, van Wijnen AJ, Stein JL, Imbalzano AN, Nickerson JA, Lian JB, Stein GS. Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression. Cancer Res. 2009 Sep 1; 69(17):6807-14.
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41.
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Cruzat F, Henriquez B, Villagra A, Hepp M, Lian JB, van Wijnen AJ, Stein JL, Imbalzano AN, Stein GS, Montecino M. SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2. Biochemistry. 2009 Aug 4; 48(30):7287-95.
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42.
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Altieri DC, Languino LR, Lian JB, Stein JL, Leav I, van Wijnen AJ, Jiang Z, Stein GS. Prostate cancer regulatory networks. J Cell Biochem. 2009 Aug 1; 107(5):845-52.
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43.
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Xie R, Medina R, Zhang Y, Hussain S, Colby J, Ghule P, Sundararajan S, Keeler M, Liu LJ, van der Deen M, Mitra P, Lian JB, Rivera-Perez JA, Jones SN, Stein JL, van Wijnen AJ, Stein GS. The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles. Proc Natl Acad Sci U S A. 2009 Jul 28; 106(30):12359-64.
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44.
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Ghule PN, Dominski Z, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types. J Cell Physiol. 2009 Jul; 220(1):129-35.
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45.
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Teplyuk NM, Haupt LM, Ling L, Dombrowski C, Mun FK, Nathan SS, Lian JB, Stein JL, Stein GS, Cool SM, van Wijnen AJ. The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts. J Cell Biochem. 2009 May 1; 107(1):144-54.
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46.
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Mitra P, Ghule PN, van der Deen M, Medina R, Xie RL, Holmes WF, Ye X, Nakayama KI, Harper JW, Stein JL, Stein GS, van Wijnen AJ. CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P. J Cell Physiol. 2009 May; 219(2):438-48.
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47.
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Li Z, Hassan MQ, Jafferji M, Aqeilan RI, Garzon R, Croce CM, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. J Biol Chem. 2009 Jun 5; 284(23):15676-84.
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48.
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Teplyuk NM, Zhang Y, Lou Y, Hawse JR, Hassan MQ, Teplyuk VI, Pratap J, Galindo M, Stein JL, Stein GS, Lian JB, van Wijnen AJ. The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts. Mol Endocrinol. 2009 Jun; 23(6):849-61.
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49.
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Pande S, Ali SA, Dowdy C, Zaidi SK, Ito K, Ito Y, Montecino MA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes. J Cell Physiol. 2009 Mar; 218(3):473-9.
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50.
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Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Transcription-factor-mediated epigenetic control of cell fate and lineage commitment. Biochem Cell Biol. 2009 Feb; 87(1):1-6.
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51.
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Stuardo M, Martinez M, Hidalgo K, Montecino M, Javed A, Lian JB, Stein GS, Stein JL, Gutiérrez SE. Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation. J Cell Physiol. 2009 Feb; 218(2):343-9.
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52.
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Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer. Ann N Y Acad Sci. 2009 Feb; 1155:4-14.
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53.
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Lou Y, Javed A, Hussain S, Colby J, Frederick D, Pratap J, Xie R, Gaur T, van Wijnen AJ, Jones SN, Stein GS, Lian JB, Stein JL. A Runx2 threshold for the cleidocranial dysplasia phenotype. Hum Mol Genet. 2009 Feb 1; 18(3):556-68.
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54.
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Zhang Y, Hassan MQ, Xie RL, Hawse JR, Spelsberg TC, Montecino M, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats). J Biol Chem. 2009 Jan 30; 284(5):3125-35.
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55.
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Bakshi R, Zaidi SK, Pande S, Hassan MQ, Young DW, Montecino M, Lian JB, van Wijnen AJ, Stein JL, Stein GS. The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes. J Cell Sci. 2008 Dec 1; 121(Pt 23):3981-90.
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56.
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Jeong JH, Jin JS, Kim HN, Kang SM, Liu JC, Lengner CJ, Otto F, Mundlos S, Stein JL, van Wijnen AJ, Lian JB, Stein GS, Choi JY. Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain. J Cell Physiol. 2008 Nov; 217(2):511-7.
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57.
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Ghule PN, Dominski Z, Yang XC, Marzluff WF, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells. Proc Natl Acad Sci U S A. 2008 Nov 4; 105(44):16964-9.
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58.
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Medina R, Buck T, Zaidi SK, Miele-Chamberland A, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif. Biochemistry. 2008 Nov 4; 47(44):11415-23.
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59.
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Pratap J, Wixted JJ, Gaur T, Zaidi SK, Dobson J, Gokul KD, Hussain S, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res. 2008 Oct 1; 68(19):7795-802.
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60.
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Zhang Y, Hassan MQ, Li ZY, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation. J Cell Biochem. 2008 Oct 1; 105(2):487-96.
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61.
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Li Z, Hassan MQ, Volinia S, van Wijnen AJ, Stein JL, Croce CM, Lian JB, Stein GS. A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13906-11.
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62.
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Javed A, Afzal F, Bae JS, Gutierrez S, Zaidi K, Pratap J, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation. Cells Tissues Organs. 2009; 189(1-4):133-7.
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63.
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Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer. J Cell Biochem. 2008 Aug 15; 104(6):2016-26.
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64.
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Hassan MQ, Saini S, Gordon JA, van Wijnen AJ, Montecino M, Stein JL, Stein GS, Lian JB. Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis. Cells Tissues Organs. 2009; 189(1-4):122-5.
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65.
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Lederman SA, Jones RL, Caldwell KL, Rauh V, Sheets SE, Tang D, Viswanathan S, Becker M, Stein JL, Wang RY, Perera FP. Relation between cord blood mercury levels and early child development in a World Trade Center cohort. Environ Health Perspect. 2008 Aug; 116(8):1085-91.
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66.
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Hall LL, Byron M, Butler J, Becker KA, Nelson A, Amit M, Itskovitz-Eldor J, Stein J, Stein G, Ware C, Lawrence JB. X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected. J Cell Physiol. 2008 Aug; 216(2):445-52.
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67.
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Teplyuk NM, Galindo M, Teplyuk VI, Pratap J, Young DW, Lapointe D, Javed A, Stein JL, Lian JB, Stein GS, van Wijnen AJ. Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors. J Biol Chem. 2008 Oct 10; 283(41):27585-97.
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68.
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Ali SA, Zaidi SK, Dacwag CS, Salma N, Young DW, Shakoori AR, Montecino MA, Lian JB, van Wijnen AJ, Imbalzano AN, Stein GS, Stein JL. Phenotypic transcription factors epigenetically mediate cell growth control. Proc Natl Acad Sci U S A. 2008 May 6; 105(18):6632-7.
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69.
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Medina R, Zaidi SK, Liu CG, Stein JL, van Wijnen AJ, Croce CM, Stein GS. MicroRNAs 221 and 222 bypass quiescence and compromise cell survival. Cancer Res. 2008 Apr 15; 68(8):2773-80.
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70.
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Lederman SA, Becker M, Sheets S, Stein J, Tang D, Weiss L, Perera FP. Modeling exposure to air pollution from the WTC disaster based on reports of perceived air pollution. Risk Anal. 2008 Apr; 28(2):287-301.
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71.
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Carvallo L, HenrÃquez B, Paredes R, Olate J, Onate S, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. 1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex. J Cell Physiol. 2008 Mar; 214(3):740-9.
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72.
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Javed A, Bae JS, Afzal F, Gutierrez S, Pratap J, Zaidi SK, Lou Y, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. J Biol Chem. 2008 Mar 28; 283(13):8412-22.
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73.
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van der Deen M, Hassan MQ, Pratap J, Teplyuk NM, Young DW, Javed A, Zaidi SK, Lian JB, Montecino M, Stein JL, Stein GS, van Wijnen AJ. Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells. Methods Mol Biol. 2008; 455:165-76.
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74.
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Montecino M, Stein GS, Stein JL, Lian JB, van Wijnen AJ, Carvallo L, Marcellini S, Cruzat F, Arriagada G. Vitamin D control of gene expression: temporal and spatial parameters for organization of the regulatory machinery. Crit Rev Eukaryot Gene Expr. 2008; 18(2):163-72.
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75.
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Pockwinse SM, Zaidi SK, Medina RF, Bakshi R, Kota KP, Ali SA, Young DW, Nickerson JA, Javed A, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. In situ nuclear organization of regulatory machinery. Methods Mol Biol. 2008; 455:239-59.
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76.
|
Zaidi SK, Pande S, Pratap J, Gaur T, Grigoriu S, Ali SA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19861-6.
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77.
|
Medina R, van der Deen M, Miele-Chamberland A, Xie RL, van Wijnen AJ, Stein JL, Stein GS. The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes. Cancer Res. 2007 Nov 1; 67(21):10334-42.
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78.
|
Ghule PN, Becker KA, Harper JW, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells. J Cell Physiol. 2007 Oct; 213(1):9-17.
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79.
|
Perera FP, Tang D, Rauh V, Tu YH, Tsai WY, Becker M, Stein JL, King J, Del Priore G, Lederman SA. Relationship between polycyclic aromatic hydrocarbon-DNA adducts, environmental tobacco smoke, and child development in the World Trade Center cohort. Environ Health Perspect. 2007 Oct; 115(10):1497-502.
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80.
|
Galindo M, Kahler RA, Teplyuk NM, Stein JL, Lian JB, Stein GS, Westendorf JJ, van Wijnen AJ. Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts. J Mol Histol. 2007 Oct; 38(5):501-6.
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81.
|
Miele A, Medina R, van Wijnen AJ, Stein GS, Stein JL. The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing. J Cell Biochem. 2007 Sep 1; 102(1):136-48.
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82.
|
Xie RL, Liu L, Mitra P, Stein JL, van Wijnen AJ, Stein GS. Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition. Gene. 2007 Nov 1; 402(1-2):94-102.
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83.
|
Montecino M, Stein JL, Stein GS, Lian JB, van Wijnen AJ, Cruzat F, Gutiérrez S, Olate J, Marcellini S, Gutiérrez JL. Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence. Biochem Cell Biol. 2007 Aug; 85(4):419-25.
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84.
|
Zaidi SK, Young DW, Javed A, Pratap J, Montecino M, van Wijnen A, Lian JB, Stein JL, Stein GS. Nuclear microenvironments in biological control and cancer. Nat Rev Cancer. 2007 Jun; 7(6):454-63.
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85.
|
Mitra P, Xie R, Harper JW, Stein JL, Stein GS, van Wijnen AJ. HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription. J Cell Biochem. 2007 May 1; 101(1):181-91.
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86.
|
Rajgopal A, Young DW, Mujeeb KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells. J Cell Biochem. 2007 Apr 15; 100(6):1509-17.
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87.
|
Stein GS, Lian JB, van Wijnen AJ, Stein JL, Javed A, Montecino M, Choi JY, Vradii D, Zaidi SK, Pratap J, Young D. Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer. Adv Enzyme Regul. 2007; 47:242-50.
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88.
|
Arriagada G, Paredes R, Olate J, van Wijnen A, Lian JB, Stein GS, Stein JL, Onate S, Montecino M. Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):425-9.
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|
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89.
|
Hassan MQ, Tare R, Lee SH, Mandeville M, Weiner B, Montecino M, van Wijnen AJ, Stein JL, Stein GS, Lian JB. HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes. Mol Cell Biol. 2007 May; 27(9):3337-52.
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90.
|
Young DW, Hassan MQ, Yang XQ, Galindo M, Javed A, Zaidi SK, Furcinitti P, Lapointe D, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3189-94.
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91.
|
Becker KA, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells. J Cell Physiol. 2007 Feb; 210(2):517-26.
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92.
|
Bae JS, Gutierrez S, Narla R, Pratap J, Devados R, van Wijnen AJ, Stein JL, Stein GS, Lian JB, Javed A. Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation. J Cell Biochem. 2007 Feb 1; 100(2):434-49.
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93.
|
Gutiérrez J, Paredes R, Cruzat F, Hill DA, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Imbalzano AN, Montecino M. Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter. J Biol Chem. 2007 Mar 30; 282(13):9445-57.
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94.
|
Young DW, Hassan MQ, Pratap J, Galindo M, Zaidi SK, Lee SH, Yang X, Xie R, Javed A, Underwood JM, Furcinitti P, Imbalzano AN, Penman S, Nickerson JA, Montecino MA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. Nature. 2007 Jan 25; 445(7126):442-6.
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95.
|
Carvallo L, Henriquez B, Olate J, van Wijnen AJ, Lian JB, Stein GS, Onate S, Stein JL, Montecino M. The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):420-4.
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96.
|
Montecino M, Stein GS, Cruzat F, Marcellini S, Stein JL, Lian JB, van Wijnen AJ, Arriagada G. An architectural perspective of vitamin D responsiveness. Arch Biochem Biophys. 2007 Apr 15; 460(2):293-9.
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97.
|
Medina R, van Wijnen AJ, Stein GS, Stein JL. The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT. Biochemistry. 2006 Dec 26; 45(51):15915-20.
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98.
|
Becker KA, Ghule PN, Therrien JA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. J Cell Physiol. 2006 Dec; 209(3):883-93.
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99.
|
Stein GS, van Wijnen AJ, Stein JL, Lian JB, Montecino M, Zaidi SK, Braastad C. An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition. J Cell Physiol. 2006 Dec; 209(3):706-10.
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100.
|
Pratap J, Lian JB, Javed A, Barnes GL, van Wijnen AJ, Stein JL, Stein GS. Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone. Cancer Metastasis Rev. 2006 Dec; 25(4):589-600.
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101.
|
Zaidi SK, Javed A, Pratap J, Schroeder TM, J Westendorf J, Lian JB, van Wijnen AJ, Stein GS, Stein JL. Alterations in intranuclear localization of Runx2 affect biological activity. J Cell Physiol. 2006 Dec; 209(3):935-42.
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102.
|
Bravo S, Paredes R, Izaurieta P, Lian JB, Stein JL, Stein GS, Hinrichs MV, Olate J, Aguayo LG, Montecino M. The classic receptor for 1alpha,25-dihydroxy vitamin D3 is required for non-genomic actions of 1alpha,25-dihydroxy vitamin D3 in osteosarcoma cells. J Cell Biochem. 2006 Nov 1; 99(4):995-1000.
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103.
|
Hassan MQ, Tare RS, Lee SH, Mandeville M, Morasso MI, Javed A, van Wijnen AJ, Stein JL, Stein GS, Lian JB. BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network. J Biol Chem. 2006 Dec 29; 281(52):40515-26.
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104.
|
Gaur T, Rich L, Lengner CJ, Hussain S, Trevant B, Ayers D, Stein JL, Bodine PV, Komm BS, Stein GS, Lian JB. Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation. J Cell Physiol. 2006 Jul; 208(1):87-96.
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105.
|
Villagra A, Cruzat F, Carvallo L, Paredes R, Olate J, van Wijnen AJ, Stein GS, Lian JB, Stein JL, Imbalzano AN, Montecino M. Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity. J Biol Chem. 2006 Aug 11; 281(32):22695-706.
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106.
|
Lian JB, Stein GS, Javed A, van Wijnen AJ, Stein JL, Montecino M, Hassan MQ, Gaur T, Lengner CJ, Young DW. Networks and hubs for the transcriptional control of osteoblastogenesis. Rev Endocr Metab Disord. 2006 Jun; 7(1-2):1-16.
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107.
|
Kim HJ, Nam SH, Kim HJ, Park HS, Ryoo HM, Kim SY, Cho TJ, Kim SG, Bae SC, Kim IS, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Choi JY. Four novel RUNX2 mutations including a splice donor site result in the cleidocranial dysplasia phenotype. J Cell Physiol. 2006 Apr; 207(1):114-22.
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108.
|
Pockwinse SM, Rajgopal A, Young DW, Mujeeb KA, Nickerson J, Javed A, Redick S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Doxsey SJ. Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2. J Cell Physiol. 2006 Feb; 206(2):354-62.
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109.
|
Vradii D, Wagner S, Doan DN, Nickerson JA, Montecino M, Lian JB, Stein JL, van Wijnen AJ, Imbalzano AN, Stein GS. Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes. J Cell Physiol. 2006 Jan; 206(1):112-8.
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110.
|
Kim YJ, Kim HN, Park EK, Lee BH, Ryoo HM, Kim SY, Kim IS, Stein JL, Lian JB, Stein GS, van Wijnen AJ, Choi JY. The bone-related Zn finger transcription factor Osterix promotes proliferation of mesenchymal cells. Gene. 2006 Jan 17; 366(1):145-51.
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111.
|
Li X, Vradii D, Gutierrez S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Javed A. Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1. J Cell Biochem. 2005 Nov 1; 96(4):795-809.
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112.
|
Pratap J, Javed A, Languino LR, van Wijnen AJ, Stein JL, Stein GS, Lian JB. The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol. 2005 Oct; 25(19):8581-91.
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113.
|
Saltman LH, Javed A, Ribadeneyra J, Hussain S, Young DW, Osdoby P, Amcheslavsky A, van Wijnen AJ, Stein JL, Stein GS, Lian JB, Bar-Shavit Z. Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1. J Cell Physiol. 2005 Sep; 204(3):871-80.
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114.
|
Stein GS, Lian JB, Stein JL, van Wijnen AJ, Javed A, Montecino M, Zaidi SK, Young DW, Choi JY, Pratap J. Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer. Adv Enzyme Regul. 2005; 45:136-54.
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115.
|
Holmes WF, Braastad CD, Mitra P, Hampe C, Doenecke D, Albig W, Stein JL, van Wijnen AJ, Stein GS. Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells. J Biol Chem. 2005 Nov 11; 280(45):37400-7.
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116.
|
Gaur T, Lengner CJ, Hovhannisyan H, Bhat RA, Bodine PV, Komm BS, Javed A, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression. J Biol Chem. 2005 Sep 30; 280(39):33132-40.
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117.
|
Miele A, Braastad CD, Holmes WF, Mitra P, Medina R, Xie R, Zaidi SK, Ye X, Wei Y, Harper JW, van Wijnen AJ, Stein JL, Stein GS. HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. Mol Cell Biol. 2005 Jul; 25(14):6140-53.
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118.
|
Afzal F, Pratap J, Ito K, Ito Y, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Javed A. Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription. J Cell Physiol. 2005 Jul; 204(1):63-72.
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119.
|
Vradii D, Zaidi SK, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype. Proc Natl Acad Sci U S A. 2005 May 17; 102(20):7174-9.
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120.
|
Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'Keefe RJ, Stein GS, Drissi MH. Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr; 203(1):133-43.
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121.
|
Galindo M, Pratap J, Young DW, Hovhannisyan H, Im HJ, Choi JY, Lian JB, Stein JL, Stein GS, van Wijnen AJ. The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. J Biol Chem. 2005 May 27; 280(21):20274-85.
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122.
|
Young DW, Pratap J, Javed A, Weiner B, Ohkawa Y, van Wijnen A, Montecino M, Stein GS, Stein JL, Imbalzano AN, Lian JB. SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation. J Cell Biochem. 2005 Mar 1; 94(4):720-30.
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123.
|
Lengner CJ, Hassan MQ, Serra RW, Lepper C, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation. J Biol Chem. 2005 Apr 22; 280(16):15872-9.
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124.
|
Zaidi SK, Young DW, Choi JY, Pratap J, Javed A, Montecino M, Stein JL, van Wijnen AJ, Lian JB, Stein GS. The dynamic organization of gene-regulatory machinery in nuclear microenvironments. EMBO Rep. 2005 Feb; 6(2):128-33.
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125.
|
Javed A, Barnes GL, Pratap J, Antkowiak T, Gerstenfeld LC, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. Proc Natl Acad Sci U S A. 2005 Feb 1; 102(5):1454-9.
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126.
|
Lederman SA, Rauh V, Weiss L, Stein JL, Hoepner LA, Becker M, Perera FP. The effects of the World Trade Center event on birth outcomes among term deliveries at three lower Manhattan hospitals. Environ Health Perspect. 2004 Dec; 112(17):1772-8.
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127.
|
Braastad CD, Hovhannisyan H, van Wijnen AJ, Stein JL, Stein GS. Functional characterization of a human histone gene cluster duplication. Gene. 2004 Nov 10; 342(1):35-40.
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128.
|
Paredes R, Arriagada G, Cruzat F, Villagra A, Olate J, Zaidi K, van Wijnen A, Lian JB, Stein GS, Stein JL, Montecino M. Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells. Mol Cell Biol. 2004 Oct; 24(20):8847-61.
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129.
|
Hassan MQ, Javed A, Morasso MI, Karlin J, Montecino M, van Wijnen AJ, Stein GS, Stein JL, Lian JB. Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene. Mol Cell Biol. 2004 Oct; 24(20):9248-61.
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130.
|
Young DW, Zaidi SK, Furcinitti PS, Javed A, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Quantitative signature for architectural organization of regulatory factors using intranuclear informatics. J Cell Sci. 2004 Oct 1; 117(Pt 21):4889-96.
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131.
|
Lengner CJ, Lepper C, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Primary mouse embryonic fibroblasts: a model of mesenchymal cartilage formation. J Cell Physiol. 2004 Sep; 200(3):327-33.
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132.
|
Gutierrez S, Liu J, Javed A, Montecino M, Stein GS, Lian JB, Stein JL. The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain. J Biol Chem. 2004 Oct 15; 279(42):43581-8.
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133.
|
Zaidi SK, Young DW, Choi JY, Pratap J, Javed A, Montecino M, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Intranuclear trafficking: organization and assembly of regulatory machinery for combinatorial biological control. J Biol Chem. 2004 Oct 15; 279(42):43363-6.
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134.
|
Stein GS, Lian JB, van Wijnen AJ, Stein JL, Montecino M, Javed A, Zaidi SK, Young DW, Choi JY, Pockwinse SM. Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene. 2004 May 24; 23(24):4315-29.
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135.
|
Paredes R, Arriagada G, Cruzat F, Olate J, Van Wijnen A, Lian J, Stein G, Stein J, Montecino M. The Runx2 transcription factor plays a key role in the 1alpha,25-dihydroxy Vitamin D3-dependent upregulation of the rat osteocalcin (OC) gene expression in osteoblastic cells. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):269-71.
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136.
|
Zaidi SK, Sullivan AJ, Medina R, Ito Y, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J. 2004 Feb 25; 23(4):790-9.
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137.
|
Stein GS, Lian JB, van Wijnen AJ, Stein JL, Javed A, Montecino M, Zaidi SK, Young D, Choi JY, Gutierrez S, Pockwinse S. Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation. J Cell Biochem. 2004 Feb 1; 91(2):287-302.
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138.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction. Methods Mol Biol. 2004; 285:63-7.
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139.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Immunofluorescence analysis using epitope-tagged proteins: in vitro system. Methods Mol Biol. 2004; 285:33-6.
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140.
|
Lian JB, Javed A, Zaidi SK, Lengner C, Montecino M, van Wijnen AJ, Stein JL, Stein GS. Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors. Crit Rev Eukaryot Gene Expr. 2004; 14(1-2):1-41.
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141.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Analysis of in vivo gene expression using epitope-tagged proteins. Methods Mol Biol. 2004; 285:37-40.
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142.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. In situ immunofluorescence analysis: immunofluorescence microscopy. Methods Mol Biol. 2004; 285:23-8.
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143.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion. Methods Mol Biol. 2004; 285:57-62.
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144.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling. Methods Mol Biol. 2004; 285:29-31.
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145.
|
Stein GS, Stein JL, Lian JB, Van Wijnen AJ, Montecino M, Javed A, Zaidi SK, Young D, Choi JY, Pockwinse S. Nuclear microenvironments: an architectural platform for the convergence and integration of transcriptional regulatory signals. Eur J Histochem. 2004; 48(1):65-76.
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146.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Chromatin immunoprecipitation. Methods Mol Biol. 2004; 285:41-4.
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147.
|
Javed A, Zaidi SK, Gutierrez SE, Lengner CJ, Harrington KS, Hovhannisyan H, Cho BC, Pratap J, Pockwinse SM, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay. Methods Mol Biol. 2004; 285:45-55.
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148.
|
Zaidi SK, Young DW, Pockwinse SM, Javed A, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells. Proc Natl Acad Sci U S A. 2003 Dec 9; 100(25):14852-7.
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149.
|
Kim JO, Kim HN, Hwang MH, Shin HI, Kim SY, Park RW, Park EY, Kim IS, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Choi JY. Differential gene expression analysis using paraffin-embedded tissues after laser microdissection. J Cell Biochem. 2003 Dec 1; 90(5):998-1006.
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150.
|
Mitra P, Xie RL, Medina R, Hovhannisyan H, Zaidi SK, Wei Y, Harper JW, Stein JL, van Wijnen AJ, Stein GS. Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase. Mol Cell Biol. 2003 Nov; 23(22):8110-23.
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151.
|
Stein GS, Zaidi SK, Braastad CD, Montecino M, van Wijnen AJ, Choi JY, Stein JL, Lian JB, Javed A. Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair. Trends Cell Biol. 2003 Nov; 13(11):584-92.
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152.
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Pratap J, Galindo M, Zaidi SK, Vradii D, Bhat BM, Robinson JA, Choi JY, Komori T, Stein JL, Lian JB, Stein GS, van Wijnen AJ. Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts. Cancer Res. 2003 Sep 1; 63(17):5357-62.
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153.
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Gupta S, Luong MX, Bleuming SA, Miele A, Luong M, Young D, Knudsen ES, Van Wijnen AJ, Stein JL, Stein GS. Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription. J Cell Physiol. 2003 Sep; 196(3):541-56.
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154.
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Lian JB, Balint E, Javed A, Drissi H, Vitti R, Quinlan EJ, Zhang L, Van Wijnen AJ, Stein JL, Speck N, Stein GS. Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo. J Cell Physiol. 2003 Aug; 196(2):301-11.
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155.
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Balint E, Lapointe D, Drissi H, van der Meijden C, Young DW, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation. J Cell Biochem. 2003 May 15; 89(2):401-26.
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156.
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Xie RL, Gupta S, Miele A, Shiffman D, Stein JL, Stein GS, van Wijnen AJ. The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter. J Biol Chem. 2003 Jul 18; 278(29):26589-96.
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157.
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Sierra J, Villagra A, Paredes R, Cruzat F, Gutierrez S, Javed A, Arriagada G, Olate J, Imschenetzky M, Van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M. Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity. Mol Cell Biol. 2003 May; 23(9):3339-51.
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158.
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Stein GS, Lian JB, Stein JL, van Wijnen AJ, Montecino M, Pratap J, Choi J, Zaidi SK, Javed A, Gutierrez S, Harrington K, Shen J, Young D. Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer. Blood Cells Mol Dis. 2003 Mar-Apr; 30(2):170-6.
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159.
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Hovhannisyan H, Cho B, Mitra P, Montecino M, Stein GS, Van Wijnen AJ, Stein JL. Maintenance of open chromatin and selective genomic occupancy at the cell cycle-regulated histone H4 promoter during differentiation of HL-60 promyelocytic leukemia cells. Mol Cell Biol. 2003 Feb; 23(4):1460-9.
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160.
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Stein GS, Lian JB, Stein JL, Wijnen AJ, Montecino M, Javed A, Pratap J, Choi J, Zaidi SK, Gutierrez S, Harrington K, Shen J, Young D. Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression. J Cell Biochem. 2003 Feb 1; 88(2):340-55.
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161.
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Shen J, Hovhannisyan H, Lian JB, Montecino MA, Stein GS, Stein JL, Van Wijnen AJ. Transcriptional induction of the osteocalcin gene during osteoblast differentiation involves acetylation of histones h3 and h4. Mol Endocrinol. 2003 Apr; 17(4):743-56.
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162.
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Lian JB, Stein JL, Stein GS, van Wijnen AJ, Montecino M, Javed A, Gutierrez S, Shen J, Zaidi SK, Drissi H. Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions. Connect Tissue Res. 2003; 44 Suppl 1:141-8.
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163.
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Stein GS, Lian JB, Montecino M, Stein JL, van Wijnen AJ, Javed A, Pratap J, Choi J, Zaidi SK, Gutierrez S, Harrington K, Shen J, Young D, Pockwinse S. Nuclear microenvironments support physiological control of gene expression. Chromosome Res. 2003; 11(5):527-36.
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164.
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Stein GS, Lian JB, Stein JL, van Wijnen AJ, Choi JY, Pratap J, Zaidi SK. Temporal and spatial parameters of skeletal gene expression: targeting RUNX factors and their coregulatory proteins to subnuclear domains. Connect Tissue Res. 2003; 44 Suppl 1:149-53.
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165.
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Barseguian K, Lutterbach B, Hiebert SW, Nickerson J, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15434-9.
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166.
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Harrington KS, Javed A, Drissi H, McNeil S, Lian JB, Stein JL, Van Wijnen AJ, Wang YL, Stein GS. Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains. J Cell Sci. 2002 Nov 1; 115(Pt 21):4167-76.
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167.
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Zaidi SK, Sullivan AJ, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8048-53.
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168.
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Lengner CJ, Drissi H, Choi JY, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton. Mech Dev. 2002 Jun; 114(1-2):167-70.
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169.
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van der Meijden CM, Lapointe DS, Luong MX, Peric-Hupkes D, Cho B, Stein JL, van Wijnen AJ, Stein GS. Gene profiling of cell cycle progression through S-phase reveals sequential expression of genes required for DNA replication and nucleosome assembly. Cancer Res. 2002 Jun 1; 62(11):3233-43.
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170.
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Paredes R, Gutiérrez J, Gutierrez S, Allison L, Puchi M, Imschenetzky M, van Wijnen A, Lian J, Stein G, Stein J, Montecino M. Interaction of the 1alpha,25-dihydroxyvitamin D3 receptor at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodelling. Biochem J. 2002 May 1; 363(Pt 3):667-76.
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171.
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Xie RL, van Wijnen AJ, van der Meijden CM, Stein JL, Stein GS. Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells. Cancer Res. 2002 May 1; 62(9):2510-5.
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172.
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Drissi H, Pouliot A, Koolloos C, Stein JL, Lian JB, Stein GS, van Wijnen AJ. 1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter. Exp Cell Res. 2002 Apr 1; 274(2):323-33.
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173.
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Shen J, Montecino M, Lian JB, Stein GS, Van Wijnen AJ, Stein JL. Histone acetylation in vivo at the osteocalcin locus is functionally linked to vitamin D-dependent, bone tissue-specific transcription. J Biol Chem. 2002 Jun 7; 277(23):20284-92.
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174.
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Luong MX, van der Meijden CM, Xing D, Hesselton R, Monuki ES, Jones SN, Lian JB, Stein JL, Stein GS, Neufeld EJ, van Wijnen AJ. Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility. Mol Cell Biol. 2002 Mar; 22(5):1424-37.
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175.
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Drissi H, Pouliot A, Stein JL, van Wijnen AJ, Stein GS, Lian JB. Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1. J Cell Biochem. 2002; 86(2):403-12.
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176.
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Villagra A, Gutiérrez J, Paredes R, Sierra J, Puchi M, Imschenetzky M, Wijnen Av A, Lian J, Stein G, Stein J, Montecino M. Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts. J Cell Biochem. 2002; 85(1):112-22.
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177.
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Gutierrez S, Javed A, Tennant DK, van Rees M, Montecino M, Stein GS, Stein JL, Lian JB. CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression. J Biol Chem. 2002 Jan 11; 277(2):1316-23.
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178.
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Mitra P, Vaughan PS, Stein JL, Stein GS, van Wijnen AJ. Purification and functional analysis of a novel leucine-zipper/nucleotide-fold protein, BZAP45, stimulating cell cycle regulated histone H4 gene transcription. Biochemistry. 2001 Sep 4; 40(35):10693-9.
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179.
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Banerjee C, Javed A, Choi JY, Green J, Rosen V, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype. Endocrinology. 2001 Sep; 142(9):4026-39.
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180.
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Zaidi SK, Javed A, Choi JY, van Wijnen AJ, Stein JL, Lian JB, Stein GS. A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene. J Cell Sci. 2001 Sep; 114(Pt 17):3093-102.
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181.
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Choi JY, Pratap J, Javed A, Zaidi SK, Xing L, Balint E, Dalamangas S, Boyce B, van Wijnen AJ, Lian JB, Stein JL, Jones SN, Stein GS. Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8650-5.
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182.
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Javed A, Barnes GL, Jasanya BO, Stein JL, Gerstenfeld L, Lian JB, Stein GS. runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins. Mol Cell Biol. 2001 Apr; 21(8):2891-905.
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183.
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Shopland LS, Byron M, Stein JL, Lian JB, Stein GS, Lawrence JB. Replication-dependent histone gene expression is related to Cajal body (CB) association but does not require sustained CB contact. Mol Biol Cell. 2001 Mar; 12(3):565-76.
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184.
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Lian JB, Stein JL, Stein GS, Montecino M, van Wijnen AJ, Javed A, Gutierrez S. Contributions of nuclear architecture and chromatin to vitamin D-dependent transcriptional control of the rat osteocalcin gene. Steroids. 2001 Mar-May; 66(3-5):159-70.
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185.
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Xie R, van Wijnen AJ, van Der Meijden C, Luong MX, Stein JL, Stein GS. The cell cycle control element of histone H4 gene transcription is maximally responsive to interferon regulatory factor pairs IRF-1/IRF-3 and IRF-1/IRF-7. J Biol Chem. 2001 May 25; 276(21):18624-32.
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186.
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Staal A, Enserink JM, Stein JL, Stein GS, van Wijnen AJ. Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2. J Cell Physiol. 2000 Nov; 185(2):269-79.
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187.
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Lian JB, Stein GS, Stein JL, van Wijnen AJ. Marrow transplantation and targeted gene therapy to the skeleton. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S146-55.
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188.
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Hoffmann H, Green J, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Expression screening of factors binding to the osteocalcin bone-specific promoter element OC box I: isolation of a novel osteoblast differentiation-specific factor. J Cell Biochem. 2000 Sep 18; 80(1):156-68.
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189.
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Drissi H, Luc Q, Shakoori R, Chuva De Sousa Lopes S, Choi JY, Terry A, Hu M, Jones S, Neil JC, Lian JB, Stein JL, Van Wijnen AJ, Stein GS. Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene. J Cell Physiol. 2000 Sep; 184(3):341-50.
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190.
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McNeil S, Javed A, Harrington KS, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies. J Cell Biochem. 2000 Jul 19; 79(1):103-12.
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191.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, Montecino M, Choi J, Zaidi K, Javed A. Intranuclear trafficking of transcription factors: implications for biological control. J Cell Sci. 2000 Jul; 113 ( Pt 14):2527-33.
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192.
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Stein GS, Lian JB, Stein JL, van Wijnen AJ. Bone tissue specific transcriptional control: options for targeting gene therapy to the skeleton. Cancer. 2000 Jun 15; 88(12 Suppl):2899-902.
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193.
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Javed A, Guo B, Hiebert S, Choi JY, Green J, Zhao SC, Osborne MA, Stifani S, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription. J Cell Sci. 2000 Jun; 113 ( Pt 12):2221-31.
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194.
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Stein GS, Montecino M, van Wijnen AJ, Stein JL, Lian JB. Nuclear structure-gene expression interrelationships: implications for aberrant gene expression in cancer. Cancer Res. 2000 Apr 15; 60(8):2067-76.
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195.
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Gordon JA, Pockwinse SM, Stewart FM, Quesenberry PJ, Nakamura T, Croce CM, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Modified intranuclear organization of regulatory factors in human acute leukemias: reversal after treatment. J Cell Biochem. 2000 Feb; 77(1):30-43.
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196.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, Montecino M, Zaidi K, Javed A. Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer. J Cell Biochem Suppl. 2000; Suppl 35:84-92.
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197.
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McNeil S, Zeng C, Harrington KS, Hiebert S, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14882-7.
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198.
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van Gurp MF, Pratap J, Luong M, Javed A, Hoffmann H, Giordano A, Stein JL, Neufeld EJ, Lian JB, Stein GS, van Wijnen AJ. The CCAAT displacement protein/cut homeodomain protein represses osteocalcin gene transcription and forms complexes with the retinoblastoma protein-related protein p107 and cyclin A. Cancer Res. 1999 Dec 1; 59(23):5980-8.
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199.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, Javed A, McNeil S, Pockwinse SM. Insight into regulatory factor targeting to transcriptionally active subnuclear sites. Exp Cell Res. 1999 Nov 25; 253(1):110-6.
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200.
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Tang L, Guo B, Javed A, Choi JY, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Zhou GW. Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2. J Biol Chem. 1999 Nov 19; 274(47):33580-6.
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201.
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Javed A, Gutierrez S, Montecino M, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization. Mol Cell Biol. 1999 Nov; 19(11):7491-500.
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202.
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Stein GS, Van Wijnen AJ, Montecino M, Stein JL, Lian JB. Nuclear structure/gene expression interrelationships. J Cell Physiol. 1999 Nov; 181(2):240-50.
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203.
|
Drissi H, Hushka D, Aslam F, Nguyen Q, Buffone E, Koff A, van Wijnen A, Lian JB, Stein JL, Stein GS. The cell cycle regulator p27kip1 contributes to growth and differentiation of osteoblasts. Cancer Res. 1999 Aug 1; 59(15):3705-11.
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204.
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Last TJ, van Wijnen AJ, de Ridder MC, Stein GS, Stein JL. The homeodomain transcription factor CDP/cut interacts with the cell cycle regulatory element of histone H4 genes packaged into nucleosomes. Mol Biol Rep. 1999 Aug; 26(3):185-94.
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205.
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Hou Z, Nguyen Q, Frenkel B, Nilsson SK, Milne M, van Wijnen AJ, Stein JL, Quesenberry P, Lian JB, Stein GS. Osteoblast-specific gene expression after transplantation of marrow cells: implications for skeletal gene therapy. Proc Natl Acad Sci U S A. 1999 Jun 22; 96(13):7294-9.
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206.
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Quesenberry PJ, Stewart FM, Zhong S, Habibian H, McAuliffe C, Reilly J, Carlson J, Dooner M, Nilsson S, Peters S, Stein G, Stein J, Emmons R, Benoit B, Bertoncello I, Becker P. Lymphohematopoietic stem cell engraftment. Ann N Y Acad Sci. 1999 Apr 30; 872:40-5; discussion 45-7.
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207.
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Lee MH, Javed A, Kim HJ, Shin HI, Gutierrez S, Choi JY, Rosen V, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Ryoo HM. Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation. J Cell Biochem. 1999 Apr 1; 73(1):114-25.
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208.
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Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Phosphorylation-mediated control of chromatin organization and transcriptional activity of the tissue-specific osteocalcin gene. J Cell Biochem. 1999 Mar 15; 72(4):586-94.
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209.
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Last TJ, van Wijnen AJ, Birnbaum MJ, Stein GS, Stein JL. Multiple interactions of the transcription factor YY1 with human histone H4 gene regulatory elements. J Cell Biochem. 1999 Mar 15; 72(4):507-16.
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210.
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Montecino M, Frenkel B, van Wijnen AJ, Lian JB, Stein GS, Stein JL. Chromatin hyperacetylation abrogates vitamin D-mediated transcriptional upregulation of the tissue-specific osteocalcin gene in vivo. Biochemistry. 1999 Jan 26; 38(4):1338-45.
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211.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, Pockwinse SH, McNeil S. Implications for interrelationships between nuclear architecture and control of gene expression under microgravity conditions. FASEB J. 1999; 13 Suppl:S157-66.
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212.
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Aslam F, McCabe L, Frenkel B, van Wijnen AJ, Stein GS, Lian JB, Stein JL. AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation. Endocrinology. 1999 Jan; 140(1):63-70.
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213.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, McNeil S, Pockwinse SM. Transcriptional control within the three-dimensional context of nuclear architecture: requirements for boundaries and direction. J Cell Biochem. 1999; Suppl 32-33:24-31.
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214.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB. Interrelationships of transcriptional machinery with nuclear architecture. Crit Rev Eukaryot Gene Expr. 1999; 9(3-4):183-90.
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215.
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Lian JB, Stein GS, Stein JL, van Wijnen AJ. Regulated expression of the bone-specific osteocalcin gene by vitamins and hormones. Vitam Horm. 1999; 55:443-509.
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216.
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Aziz F, van Wijnen AJ, Stein JL, Stein GS. HiNF-D (CDP-cut/CDC2/cyclin A/pRB-complex) influences the timing of IRF-2-dependent cell cycle activation of human histone H4 gene transcription at the G1/S phase transition. J Cell Physiol. 1998 Dec; 177(3):453-64.
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217.
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Last TJ, Birnbaum M, van Wijnen AJ, Stein GS, Stein JL. Repressor elements in the coding region of the human histone H4 gene interact with the transcription factor CDP/cut. Gene. 1998 Oct 23; 221(2):267-77.
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218.
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van der Meijden CM, Vaughan PS, Staal A, Albig W, Doenecke D, Stein JL, Stein GS, van Wijnen AJ. Selective expression of specific histone H4 genes reflects distinctions in transcription factor interactions with divergent H4 promoter elements. Biochim Biophys Acta. 1998 Oct 23; 1442(1):82-100.
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219.
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Choi JY, van Wijnen AJ, Aslam F, Leszyk JD, Stein JL, Stein GS, Lian JB, Penman S. Developmental association of the beta-galactoside-binding protein galectin-1 with the nuclear matrix of rat calvarial osteoblasts. J Cell Sci. 1998 Oct; 111 ( Pt 20):3035-43.
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220.
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Tang L, Guo B, van Wijnen AJ, Lian JB, Stein JL, Stein GS, Zhou GW. Preliminary crystallographic study of glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor AML-1/CBF-alpha2. J Struct Biol. 1998 Sep; 123(1):83-5.
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221.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB. Nuclear structure--skeletal gene expression interrelationships. Front Biosci. 1998; 3:d849-64.
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222.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, Pockwinse S, McNeil S. Interrelationships of nuclear structure and transcriptional control: functional consequences of being in the right place at the right time. J Cell Biochem. 1998 Aug 1; 70(2):200-12.
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223.
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Lindenmuth D, van Wijnen AJ, Penman S, Stein JL, Stein GS, Lian JB. TGF-beta1 modifications in nuclear matrix proteins of osteoblasts during differentiation. J Cell Biochem. 1998 Jun 1; 69(3):291-303.
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224.
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Shalhoub V, Aslam F, Breen E, van Wijnen A, Bortell R, Stein GS, Stein JL, Lian JB. Multiple levels of steroid hormone-dependent control of osteocalcin during osteoblast differentiation: glucocorticoid regulation of basal and vitamin D stimulated gene expression. J Cell Biochem. 1998 May 1; 69(2):154-68.
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225.
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McNeil S, Guo B, Stein JL, Lian JB, Bushmeyer S, Seto E, Atchison ML, Penman S, van Wijnen AJ, Stein GS. Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking. J Cell Biochem. 1998 Mar 15; 68(4):500-10.
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226.
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Robinson JJ, Stein JL, Cavanaugh CM. Cloning and sequencing of a form II ribulose-1,5-biphosphate carboxylase/oxygenase from the bacterial symbiont of the hydrothermal vent tubeworm Riftia pachyptila. J Bacteriol. 1998 Mar; 180(6):1596-9.
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227.
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Zeng C, McNeil S, Pockwinse S, Nickerson J, Shopland L, Lawrence JB, Penman S, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains. Proc Natl Acad Sci U S A. 1998 Feb 17; 95(4):1585-9.
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228.
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Lian JB, Stein GS, Stein JL, van Wijnen AJ. Transcriptional control of osteoblast differentiation. Biochem Soc Trans. 1998 Feb; 26(1):14-21.
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229.
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Vaughan PS, van der Meijden CM, Aziz F, Harada H, Taniguchi T, van Wijnen AJ, Stein JL, Stein GS. Cell cycle regulation of histone H4 gene transcription requires the oncogenic factor IRF-2. J Biol Chem. 1998 Jan 2; 273(1):194-9.
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230.
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Aziz F, van Wijnen AJ, Vaughan PS, Wu S, Shakoori AR, Lian JB, Soprano KJ, Stein JL, Stein GS. The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes. Mol Biol Rep. 1998 Jan; 25(1):1-12.
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231.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, Pockwinse SM, McNeil S. Linkages of nuclear architecture to biological and pathological control of gene expression. J Cell Biochem Suppl. 1998; 30-31:220-31.
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232.
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Bagchi M, Ansari SA, Lindenmuth DM, van Wijnen AJ, Lian J, Stein JL, Stein GS. Nuclear matrix associated DNA-binding proteins of ocular lens epithelial cells. Mol Biol Rep. 1998 Jan; 25(1):13-9.
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233.
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Lian JB, Stein GS, Stein JL, van Wijnen AJ. Osteocalcin gene promoter: unlocking the secrets for regulation of osteoblast growth and differentiation. J Cell Biochem Suppl. 1998; 30-31:62-72.
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234.
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Lynch MP, Capparelli C, Stein JL, Stein GS, Lian JB. Apoptosis during bone-like tissue development in vitro. J Cell Biochem. 1998 Jan 1; 68(1):31-49.
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235.
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Guo B, Stein JL, van Wijnen AJ, Stein GS. ATF1 and CREB trans-activate a cell cycle regulated histone H4 gene at a distal nuclear matrix associated promoter element. Biochemistry. 1997 Nov 25; 36(47):14447-55.
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236.
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Ryoo HM, Hoffmann HM, Beumer T, Frenkel B, Towler DA, Stein GS, Stein JL, van Wijnen AJ, Lian JB. Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression. Mol Endocrinol. 1997 Oct; 11(11):1681-94.
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237.
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van Wijnen AJ, Cooper C, Odgren P, Aziz F, De Luca A, Shakoori RA, Giordano A, Quesenberry PJ, Lian JB, Stein GS, Stein JL. Cell cycle-dependent modifications in activities of pRb-related tumor suppressors and proliferation-specific CDP/cut homeodomain factors in murine hematopoietic progenitor cells. J Cell Biochem. 1997 Sep 15; 66(4):512-23.
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238.
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Birnbaum MJ, van Zundert B, Vaughan PS, Whitmarsh AJ, van Wijnen AJ, Davis RJ, Stein GS, Stein JL. Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo. J Cell Biochem. 1997 Aug 1; 66(2):175-83.
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239.
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Stein GS, Lian JB, van Wijnen AJ, Stein JL. The osteocalcin gene: a model for multiple parameters of skeletal-specific transcriptional control. Mol Biol Rep. 1997 Aug; 24(3):185-96.
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240.
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Smith E, Frenkel B, MacLachlan TK, Giordano A, Stein JL, Lian JB, Stein GS. Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: inhibition by proliferating osteoblasts and osteosarcoma cells. J Cell Biochem. 1997 Aug 1; 66(2):141-52.
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241.
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Banerjee C, McCabe LR, Choi JY, Hiebert SW, Stein JL, Stein GS, Lian JB. Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex. J Cell Biochem. 1997 Jul 1; 66(1):1-8.
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242.
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Lindenmuth DM, van Wijnen AJ, Hiebert S, Stein JL, Lian JB, Stein GS. Subcellular partitioning of transcription factors during osteoblast differentiation: developmental association of the AML/CBF alpha/PEBP2 alpha-related transcription factor-NMP-2 with the nuclear matrix. J Cell Biochem. 1997 Jul 1; 66(1):123-32.
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243.
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Zeng C, van Wijnen AJ, Stein JL, Meyers S, Sun W, Shopland L, Lawrence JB, Penman S, Lian JB, Stein GS, Hiebert SW. Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6746-51.
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244.
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Lian JB, Shalhoub V, Aslam F, Frenkel B, Green J, Hamrah M, Stein GS, Stein JL. Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression. Endocrinology. 1997 May; 138(5):2117-27.
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245.
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Frenkel B, Capparelli C, Van Auken M, Baran D, Bryan J, Stein JL, Stein GS, Lian JB. Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex. Endocrinology. 1997 May; 138(5):2109-16.
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246.
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Vaughan PS, van Wijnen AJ, Stein JL, Stein GS. Interferon regulatory factors: growth control and histone gene regulation--it's not just interferon anymore. J Mol Med. 1997 May; 75(5):348-59.
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247.
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Pockwinse SM, Krockmalnic G, Doxsey SJ, Nickerson J, Lian JB, van Wijnen AJ, Stein JL, Stein GS, Penman S. Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold. Proc Natl Acad Sci U S A. 1997 Apr 1; 94(7):3022-7.
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248.
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Guo B, Aslam F, van Wijnen AJ, Roberts SG, Frenkel B, Green MR, DeLuca H, Lian JB, Stein GS, Stein JL. YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene. Proc Natl Acad Sci U S A. 1997 Jan 7; 94(1):121-6.
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249.
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Ryoo HM, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display. J Cell Biochem. 1997 Jan; 64(1):106-16.
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250.
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Montecino M, Frenkel B, Lian J, Stein J, Stein G. Requirement of distal and proximal promoter sequences for chromatin organization of the osteocalcin gene in bone-derived cells. J Cell Biochem. 1996 Nov 1; 63(2):221-8.
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251.
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Staal A, van Wijnen AJ, Birkenhäger JC, Pols HA, Prahl J, DeLuca H, Gaub MP, Lian JB, Stein GS, van Leeuwen JP, Stein JL. Distinct conformations of vitamin D receptor/retinoid X receptor-alpha heterodimers are specified by dinucleotide differences in the vitamin D-responsive elements of the osteocalcin and osteopontin genes. Mol Endocrinol. 1996 Nov; 10(11):1444-56.
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252.
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van Wijnen AJ, van Gurp MF, de Ridder MC, Tufarelli C, Last TJ, Birnbaum M, Vaughan PS, Giordano A, Krek W, Neufeld EJ, Stein JL, Stein GS. CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11516-21.
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253.
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McCabe LR, Banerjee C, Kundu R, Harrison RJ, Dobner PR, Stein JL, Lian JB, Stein GS. Developmental expression and activities of specific fos and jun proteins are functionally related to osteoblast maturation: role of Fra-2 and Jun D during differentiation. Endocrinology. 1996 Oct; 137(10):4398-408.
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254.
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Stein GS, Stein JL, Lian JB, van Wijnen AJ, Montecino M. Functional interrelationships between nuclear structure and transcriptional control: contributions to regulation of cell cycle- and tissue-specific gene expression. J Cell Biochem. 1996 Aug; 62(2):198-209.
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255.
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Banerjee C, Hiebert SW, Stein JL, Lian JB, Stein GS. An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene. Proc Natl Acad Sci U S A. 1996 May 14; 93(10):4968-73.
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256.
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Banerjee C, Stein JL, Van Wijnen AJ, Frenkel B, Lian JB, Stein GS. Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site. Endocrinology. 1996 May; 137(5):1991-2000.
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257.
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Staal A, Van Wijnen AJ, Desai RK, Pols HA, Birkenhäger JC, Deluca HF, Denhardt DT, Stein JL, Van Leeuwen JP, Stein GS, Lian JB. Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements. Endocrinology. 1996 May; 137(5):2001-11.
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258.
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Hoffmann HM, Beumer TL, Rahman S, McCabe LR, Banerjee C, Aslam F, Tiro JA, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Bone tissue-specific transcription of the osteocalcin gene: role of an activator osteoblast-specific complex and suppressor hox proteins that bind the OC box. J Cell Biochem. 1996 May; 61(2):310-24.
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259.
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Montecino M, Lian J, Stein G, Stein J. Changes in chromatin structure support constitutive and developmentally regulated transcription of the bone-specific osteocalcin gene in osteoblastic cells. Biochemistry. 1996 Apr 16; 35(15):5093-102.
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260.
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Stein GS, Lian JB, Stein JL, Van Wijnen AJ, Montecino M. Transcriptional control of osteoblast growth and differentiation. Physiol Rev. 1996 Apr; 76(2):593-629.
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261.
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Tang KT, Capparelli C, Stein JL, Stein GS, Lian JB, Huber AC, Braverman LE, DeVito WJ. Acidic fibroblast growth factor inhibits osteoblast differentiation in vitro: altered expression of collagenase, cell growth-related, and mineralization-associated genes. J Cell Biochem. 1996 Apr; 61(1):152-66.
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262.
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Frenkel B, Montecino M, Green J, Aslam F, Desai R, Banerjee C, Stein JL, Lian JB, Stein GS. Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: requirement of upstream sequences for control by the proximal regulatory domain. Endocrinology. 1996 Mar; 137(3):1080-88.
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263.
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Stein JL, van Wijnen AJ, Lian JB, Stein GS. Control of cell cycle regulated histone genes during proliferation and differentiation. Int J Obes Relat Metab Disord. 1996 Mar; 20 Suppl 3:S84-90.
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264.
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Stein GS, Stein JL, Van Wijnen AJ, Lian JB. Transcriptional control of cell cycle progression: the histone gene is a paradigm for the G1/S phase and proliferation/differentiation transitions. Cell Biol Int. 1996 Jan; 20(1):41-9.
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265.
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Lian JB, Stein GS, Stein JL, Van Wijnen A, McCabe L, Banerjee C, Hoffmann H. The osteocalcin gene promoter provides a molecular blueprint for regulatory mechanisms controlling bone tissue formation: role of transcription factors involved in development. Connect Tissue Res. 1996; 35(1-4):15-21.
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266.
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Birnbaum MJ, van Wijnen AJ, Odgren PR, Last TJ, Suske G, Stein GS, Stein JL. Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3. Biochemistry. 1995 Dec 19; 34(50):16503-8.
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267.
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Desai RK, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Control of 1,25-dihydroxyvitamin D3 receptor-mediated enhancement of osteocalcin gene transcription: effects of perturbing phosphorylation pathways by okadaic acid and staurosporine. Endocrinology. 1995 Dec; 136(12):5685-93.
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268.
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Guo B, Odgren PR, van Wijnen AJ, Last TJ, Nickerson J, Penman S, Lian JB, Stein JL, Stein GS. The nuclear matrix protein NMP-1 is the transcription factor YY1. Proc Natl Acad Sci U S A. 1995 Nov 7; 92(23):10526-30.
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269.
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Smith E, Frenkel B, Schlegel R, Giordano A, Lian JB, Stein JL, Stein GS. Expression of cell cycle regulatory factors in differentiating osteoblasts: postproliferative up-regulation of cyclins B and E. Cancer Res. 1995 Nov 1; 55(21):5019-24.
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270.
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Merriman HL, van Wijnen AJ, Hiebert S, Bidwell JP, Fey E, Lian J, Stein J, Stein GS. The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: interactions with the osteocalcin gene promoter. Biochemistry. 1995 Oct 10; 34(40):13125-32.
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271.
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Vaughan PS, Aziz F, van Wijnen AJ, Wu S, Harada H, Taniguchi T, Soprano KJ, Stein JL, Stein GS. Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2. Nature. 1995 Sep 28; 377(6547):362-5.
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272.
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Stein GS, Stein JL, van Wijnen A, Lian JB, Quesenberry PJ. Molecular mechanisms mediating control of cell cycle and cell growth. Exp Hematol. 1995 Sep; 23(10):1053-61.
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273.
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Wright KL, Birnbaum MJ, van Wijnen AJ, Stein GS, Stein JL. Bipartite structure of the proximal promoter of a human H4 histone gene. J Cell Biochem. 1995 Jul; 58(3):372-9.
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274.
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Aslam F, Shalhoub V, van Wijnen AJ, Banerjee C, Bortell R, Shakoori AR, Litwack G, Stein JL, Stein GS, Lian JB. Contributions of distal and proximal promoter elements to glucocorticoid regulation of osteocalcin gene transcription. Mol Endocrinol. 1995 Jun; 9(6):679-90.
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275.
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Ramsey-Ewing AL, Bortell R, Stein GS, Stein JL. Histone H4 proximal promoter mediates a complex transcriptional response during differentiation of 3T3L1 adipocytes. J Cell Physiol. 1995 May; 163(2):312-20.
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276.
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McCabe LR, Kockx M, Lian J, Stein J, Stein G. Selective expression of fos- and jun-related genes during osteoblast proliferation and differentiation. Exp Cell Res. 1995 May; 218(1):255-62.
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277.
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Kroeger PE, van Wijnen AJ, Pauli U, Wright KL, Stein GS, Stein JL. In vivo occupancy of histone gene proximal promoter elements reflects gene copy number-dependent titratable transactivation factors and cross-species compatibility of regulatory sequences. J Cell Biochem. 1995 Feb; 57(2):191-207.
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278.
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Pockwinse SM, Stein JL, Lian JB, Stein GS. Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization. Exp Cell Res. 1995 Jan; 216(1):244-60.
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279.
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Heinrichs AA, Bortell R, Bourke M, Lian JB, Stein GS, Stein JL. Proximal promoter binding protein contributes to developmental, tissue-restricted expression of the rat osteocalcin gene. J Cell Biochem. 1995 Jan; 57(1):90-100.
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280.
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Lynch MP, Stein JL, Stein GS, Lian JB. The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization. Exp Cell Res. 1995 Jan; 216(1):35-45.
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281.
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Stein GS, van Wijnen AJ, Stein J, Lian JB, Montecino M. Contributions of nuclear architecture to transcriptional control. Int Rev Cytol. 1995; 162A:251-78.
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282.
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Hoffmann HM, Catron KM, van Wijnen AJ, McCabe LR, Lian JB, Stein GS, Stein JL. Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteins. Proc Natl Acad Sci U S A. 1994 Dec 20; 91(26):12887-91.
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283.
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Breen EC, van Wijnen AJ, Lian JB, Stein GS, Stein JL. In vivo occupancy of the vitamin D responsive element in the osteocalcin gene supports vitamin D-dependent transcriptional upregulation in intact cells. Proc Natl Acad Sci U S A. 1994 Dec 20; 91(26):12902-6.
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284.
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Frenkel B, Montecino M, Stein JL, Lian JB, Stein GS. A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements. Proc Natl Acad Sci U S A. 1994 Nov 8; 91(23):10923-7.
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285.
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McCabe LR, Last TJ, Lynch M, Lian J, Stein J, Stein G. Expression of cell growth and bone phenotypic genes during the cell cycle of normal diploid osteoblasts and osteosarcoma cells. J Cell Biochem. 1994 Oct; 56(2):274-82.
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286.
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Breen EC, Ignotz RA, McCabe L, Stein JL, Stein GS, Lian JB. TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype. J Cell Physiol. 1994 Aug; 160(2):323-35.
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287.
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Shalhoub V, Bortell R, Jackson ME, Marks SC, Stein JL, Lian JB, Stein GS. Transcriptionally active nuclei isolated from intact bone reflect modified levels of gene expression in skeletal development and pathology. J Cell Biochem. 1994 Jun; 55(2):182-9.
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288.
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van den Ent FM, van Wijnen AJ, Lian JB, Stein JL, Stein GS. Cell cycle controlled histone H1, H3, and H4 genes share unusual arrangements of recognition motifs for HiNF-D supporting a coordinate promoter binding mechanism. J Cell Physiol. 1994 Jun; 159(3):515-30.
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289.
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Shakoori AR, van Wijnen AJ, Bortell R, Owen TA, Stein JL, Lian JB, Stein GS. Variations in vitamin D receptor transcription factor complexes associated with the osteocalcin gene vitamin D responsive element in osteoblasts and osteosarcoma cells. J Cell Biochem. 1994 Jun; 55(2):218-29.
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290.
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Ramsey-Ewing A, Van Wijnen AJ, Stein GS, Stein JL. Delineation of a human histone H4 cell cycle element in vivo: the master switch for H4 gene transcription. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4475-9.
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291.
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Stein GS, van Wijnen AJ, Stein JL, Lian JB, Bidwell JP, Montecino M. Nuclear architecture supports integration of physiological regulatory signals for transcription of cell growth and tissue-specific genes during osteoblast differentiation. J Cell Biochem. 1994 May; 55(1):4-15.
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292.
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Bidwell JP, van Wijnen AJ, Fey EG, Merriman H, Penman S, Stein JL, Stein GS, Lian JB. Subnuclear distribution of the vitamin D receptor. J Cell Biochem. 1994 Apr; 54(4):494-500.
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293.
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Stein GS, Stein JL, van Wijnen AJ, Lian JB. Histone gene transcription: a model for responsiveness to an integrated series of regulatory signals mediating cell cycle control and proliferation/differentiation interrelationships. J Cell Biochem. 1994 Apr; 54(4):393-404.
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294.
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Bidwell J, van Wijnen A, Banerjee C, Fey E, Merriman H, Penman S, Stein J, Lian J, Stein G. Parathyroid-responsive modifications in the nuclear matrix of ROS 17/2.8 rat osteosarcoma cells. Endocrinology. 1994 Apr; 134(4):1738-44.
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295.
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Bortell R, Owen TA, Ignotz R, Stein GS, Stein JL. TGF beta 1 prevents the down-regulation of type I procollagen, fibronectin, and TGF beta 1 gene expression associated with 3T3-L1 pre-adipocyte differentiation. J Cell Biochem. 1994 Feb; 54(2):256-63.
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296.
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Montecino M, Pockwinse S, Lian J, Stein G, Stein J. DNase I hypersensitive sites in promoter elements associated with basal and vitamin D dependent transcription of the bone-specific osteocalcin gene. Biochemistry. 1994 Jan 11; 33(1):348-53.
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297.
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Bidwell JP, Fey EG, van Wijnen AJ, Penman S, Stein JL, Lian JB, Stein GS. Nuclear matrix proteins distinguish normal diploid osteoblasts from osteosarcoma cells. Cancer Res. 1994 Jan 1; 54(1):28-32.
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298.
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Kockx M, McCabe L, Stein JL, Lian JB, Stein GS. Influence of DNA replication inhibition on expression of cell growth and tissue-specific genes in osteoblasts and osteosarcoma cells. J Cell Biochem. 1994 Jan; 54(1):47-55.
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299.
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Frenkel B, Mijnes J, Aronow MA, Zambetti G, Banerjee C, Stein JL, Lian JB, Stein GS. Position and orientation-selective silencer in protein-coding sequences of the rat osteocalcin gene. Biochemistry. 1993 Dec 14; 32(49):13636-43.
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300.
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Rahman S, Oberdorf A, Montecino M, Tanhauser SM, Lian JB, Stein GS, Laipis PJ, Stein JL. Multiple copies of the bone-specific osteocalcin gene in mouse and rat. Endocrinology. 1993 Dec; 133(6):3050-3.
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301.
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Heinrichs AA, Banerjee C, Bortell R, Owen TA, Stein JL, Stein GS, Lian JB. Identification and characterization of two proximal elements in the rat osteocalcin gene promoter that may confer species-specific regulation. J Cell Biochem. 1993 Nov; 53(3):240-50.
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302.
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Heinrichs AA, Bortell R, Rahman S, Stein JL, Alnemri ES, Litwack G, Lian JB, Stein GS. Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter. Biochemistry. 1993 Oct 26; 32(42):11436-44.
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303.
|
van Wijnen AJ, Bidwell JP, Fey EG, Penman S, Lian JB, Stein JL, Stein GS. Nuclear matrix association of multiple sequence-specific DNA binding activities related to SP-1, ATF, CCAAT, C/EBP, OCT-1, and AP-1. Biochemistry. 1993 Aug 24; 32(33):8397-402.
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304.
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van den Ent FM, van Wijnen AJ, Last TJ, Bortell R, Stein JL, Lian JB, Stein GS. Concerted control of multiple histone promoter factors during cell density inhibition of proliferation in osteosarcoma cells: reciprocal regulation of cell cycle-controlled and bone-related genes. Cancer Res. 1993 May 15; 53(10 Suppl):2399-409.
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305.
|
Pockwinse SM, Lawrence JB, Singer RH, Stein JL, Lian JB, Stein GS. Gene expression at single cell resolution associated with development of the bone cell phenotype: ultrastructural and in situ hybridization analysis. Bone. 1993 May-Jun; 14(3):347-52.
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306.
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Bidwell JP, Van Wijnen AJ, Fey EG, Dworetzky S, Penman S, Stein JL, Lian JB, Stein GS. Osteocalcin gene promoter-binding factors are tissue-specific nuclear matrix components. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3162-6.
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307.
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Shakoori AR, Owen TA, Shalhoub V, Stein JL, Bustin M, Stein GS, Lian JB. Differential expression of the chromosomal high mobility group proteins 14 and 17 during the onset of differentiation in mammalian osteoblasts and promyelocytic leukemia cells. J Cell Biochem. 1993 Apr; 51(4):479-87.
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308.
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Bortell R, Owen TA, Shalhoub V, Heinrichs A, Aronow MA, Rochette-Egly C, Lutz Y, Stein JL, Lian JB, Stein GS. Constitutive transcription of the osteocalcin gene in osteosarcoma cells is reflected by altered protein-DNA interactions at promoter regulatory elements. Proc Natl Acad Sci U S A. 1993 Mar 15; 90(6):2300-4.
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309.
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Owen TA, Bortell R, Shalhoub V, Heinrichs A, Stein JL, Stein GS, Lian JB. Postproliferative transcription of the rat osteocalcin gene is reflected by vitamin D-responsive developmental modifications in protein-DNA interactions at basal and enhancer promoter elements. Proc Natl Acad Sci U S A. 1993 Feb 15; 90(4):1503-7.
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310.
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Collart D, Romain PL, Huebner K, Pockwinse S, Pilapil S, Cannizzaro LA, Lian JB, Croce CM, Stein JL, Stein GS. A human histone H2B.1 variant gene, located on chromosome 1, utilizes alternative 3' end processing. J Cell Biochem. 1992 Dec; 50(4):374-85.
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311.
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Bortell R, van Wijnen AJ, Ramsey-Ewing AL, Stein GS, Stein JL. Differential regulation of H4 histone gene expression in 3T3-L1 pre-adipocytes during arrest of proliferation following contact inhibition or differentiation and its modulation by TGF beta 1. J Cell Biochem. 1992 Sep; 50(1):62-72.
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312.
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van Wijnen AJ, van den Ent FM, Lian JB, Stein JL, Stein GS. Overlapping and CpG methylation-sensitive protein-DNA interactions at the histone H4 transcriptional cell cycle domain: distinctions between two human H4 gene promoters. Mol Cell Biol. 1992 Jul; 12(7):3273-87.
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313.
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Bortell R, Owen TA, Bidwell JP, Gavazzo P, Breen E, van Wijnen AJ, DeLuca HF, Stein JL, Lian JB, Stein GS. Vitamin D-responsive protein-DNA interactions at multiple promoter regulatory elements that contribute to the level of rat osteocalcin gene expression. Proc Natl Acad Sci U S A. 1992 Jul 1; 89(13):6119-23.
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314.
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Gerbaulet SP, van Wijnen AJ, Aronin N, Tassinari MS, Lian JB, Stein JL, Stein GS. Downregulation of histone H4 gene transcription during postnatal development in transgenic mice and at the onset of differentiation in transgenically derived calvarial osteoblast cultures. J Cell Biochem. 1992 Jun; 49(2):137-47.
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315.
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Dworetzky SI, Wright KL, Fey EG, Penman S, Lian JB, Stein JL, Stein GS. Sequence-specific DNA-binding proteins are components of a nuclear matrix-attachment site. Proc Natl Acad Sci U S A. 1992 May 1; 89(9):4178-82.
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316.
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van der Houven van Oordt CW, van Wijnen AJ, Carter R, Soprano K, Lian JB, Stein GS, Stein JL. Protein-DNA interactions at the H4-site III upstream transcriptional element of a cell cycle regulated histone H4 gene: differences in normal versus tumor cells. J Cell Biochem. 1992 May; 49(1):93-110.
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317.
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Stein GS, Stein JL, van Wijnen AJ, Lian JB. Regulation of histone gene expression. Curr Opin Cell Biol. 1992 Apr; 4(2):166-73.
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318.
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Wright KL, Dell'Orco RT, van Wijnen AJ, Stein JL, Stein GS. Multiple mechanisms regulate the proliferation-specific histone gene transcription factor HiNF-D in normal human diploid fibroblasts. Biochemistry. 1992 Mar 17; 31(10):2812-8.
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319.
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van Wijnen AJ, Bidwell J, Lian JB, Stein JL, Stein GS. Stairway assays: rapid localization of multiple protein/DNA interaction sites in gene-regulatory 5' regions. Biotechniques. 1992 Mar; 12(3):400-7.
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320.
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Shakoori AR, Oberdorf AM, Owen TA, Weber LA, Hickey E, Stein JL, Lian JB, Stein GS. Expression of heat shock genes during differentiation of mammalian osteoblasts and promyelocytic leukemia cells. J Cell Biochem. 1992 Mar; 48(3):277-87.
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321.
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van Wijnen AJ, Lian JB, Stein JL, Stein GS. Protein/DNA interactions involving ATF/AP1-, CCAAT-, and HiNF-D-related factors in the human H3-ST519 histone promoter: cross-competition with transcription regulatory sites in cell cycle controlled H4 and H1 histone genes. J Cell Biochem. 1991 Dec; 47(4):337-51.
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322.
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van Wijnen AJ, Owen TA, Holthuis J, Lian JB, Stein JL, Stein GS. Coordination of protein-DNA interactions in the promoters of human H4, H3, and H1 histone genes during the cell cycle, tumorigenesis, and development. J Cell Physiol. 1991 Jul; 148(1):174-89.
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323.
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Allen BS, Stein JL, Stein GS, Ostrer H. Single-copy flanking sequences in human histone gene clusters map to chromosomes 1 and 6. Genomics. 1991 Jun; 10(2):486-8.
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324.
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van Wijnen AJ, Ramsey-Ewing AL, Bortell R, Owen TA, Lian JB, Stein JL, Stein GS. Transcriptional element H4-site II of cell cycle regulated human H4 histone genes is a multipartite protein/DNA interaction site for factors HiNF-D, HiNF-M, and HiNF-P: involvement of phosphorylation. J Cell Biochem. 1991 Jun; 46(2):174-89.
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325.
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van Wijnen AJ, Choi TK, Owen TA, Wright KL, Lian JB, Jaenisch R, Stein JL, Stein GS. Involvement of the cell cycle-regulated nuclear factor HiNF-D in cell growth control of a human H4 histone gene during hepatic development in transgenic mice. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2573-7.
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326.
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Collart D, Ramsey-Ewing A, Bortell R, Lian J, Stein J, Stein G. Isolation and characterization of a cDNA from a human histone H2B gene which is reciprocally expressed in relation to replication-dependent H2B histone genes during HL60 cell differentiation. Biochemistry. 1991 Feb 12; 30(6):1610-7.
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327.
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Morris TD, Weber LA, Hickey E, Stein GS, Stein JL. Changes in the stability of a human H3 histone mRNA during the HeLa cell cycle. Mol Cell Biol. 1991 Jan; 11(1):544-53.
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328.
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Zambetti G, Ramsey-Ewing A, Bortell R, Stein G, Stein J. Disruption of the cytoskeleton with cytochalasin D induces c-fos gene expression. Exp Cell Res. 1991 Jan; 192(1):93-101.
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329.
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Zambetti G, Wilming L, Fey EG, Penman S, Stein J, Stein G. Differential association of membrane-bound and non-membrane-bound polysomes with the cytoskeleton. Exp Cell Res. 1990 Dec; 191(2):246-55.
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330.
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Stein JL, Haygood M, Felbeck H. Nucleotide sequence and expression of a deep-sea ribulose-1,5-bisphosphate carboxylase gene cloned from a chemoautotrophic bacterial endosymbiont. Proc Natl Acad Sci U S A. 1990 Nov; 87(22):8850-4.
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331.
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Zambetti G, Fey EG, Penman S, Stein J, Stein G. Multiple types of mRNA-cytoskeleton interactions. J Cell Biochem. 1990 Nov; 44(3):177-87.
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332.
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Grimes SR, Wolfe SA, Anderson JV, Stein GS, Stein JL. Structural and functional analysis of the rat testis-specific histone H1t gene. J Cell Biochem. 1990 Sep; 44(1):1-17.
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333.
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Zambetti G, Stein J, Stein G. Role of messenger RNA subcellular localization in the posttranscriptional regulation of human histone gene expression. J Cell Physiol. 1990 Jul; 144(1):175-82.
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334.
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Dworetzky SI, Fey EG, Penman S, Lian JB, Stein JL, Stein GS. Progressive changes in the protein composition of the nuclear matrix during rat osteoblast differentiation. Proc Natl Acad Sci U S A. 1990 Jun; 87(12):4605-9.
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335.
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Markose ER, Stein JL, Stein GS, Lian JB. Vitamin D-mediated modifications in protein-DNA interactions at two promoter elements of the osteocalcin gene. Proc Natl Acad Sci U S A. 1990 Mar; 87(5):1701-5.
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336.
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Stein GS, Stein JL, Lian JB, Van Wijnen AJ, Wright KL, Pauli U. Modifications in molecular mechanisms associated with control of cell cycle regulated human histone gene expression during differentiation. Cell Biophys. 1989 Dec; 15(3):201-23.
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337.
|
van Wijnen AJ, Wright KL, Lian JB, Stein JL, Stein GS. Human H4 histone gene transcription requires the proliferation-specific nuclear factor HiNF-D. Auxiliary roles for HiNF-C (Sp1-like) and HiNF-A (high mobility group-like). J Biol Chem. 1989 Sep 5; 264(25):15034-42.
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338.
|
Pauli U, Chiu JF, Ditullio P, Kroeger P, Shalhoub V, Rowe T, Stein G, Stein J. Specific interactions of histone H1 and a 45 kilodalton nuclear protein with a putative matrix attachment site in the distal promoter region of a cell cycle-regulated human histone gene. J Cell Physiol. 1989 May; 139(2):320-8.
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339.
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Stein G, Lian J, Stein J, Briggs R, Shalhoub V, Wright K, Pauli U, van Wijnen A. Altered binding of human histone gene transcription factors during the shutdown of proliferation and onset of differentiation in HL-60 cells. Proc Natl Acad Sci U S A. 1989 Mar; 86(6):1865-9.
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340.
|
Collar DG, Wright KL, van Wijnen AJ, Ramsey AL, Lian J, Stein JL, Stein GS. The human H1 histone gene FNC16 is functionally expressed in proliferating HeLa S3 cells and is down-regulated during terminal differentiation in HL60 cells. J Biol Chem. 1988 Nov 5; 263(31):15860-3.
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341.
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van Wijnen AJ, Massung RF, Stein JL, Stein GS. Human H1 histone gene promoter CCAAT box binding protein HiNF-B is a mosaic factor. Biochemistry. 1988 Aug 23; 27(17):6534-41.
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342.
|
Moreno ML, Pauli U, Chrysogelos S, Stein JL, Stein GS. Persistence of a micrococcal nuclease sensitive region spanning the promoter-coding region junction of a cell cycle regulated human H4 histone gene throughout the cell cycle. Biochem Cell Biol. 1988 Feb; 66(2):132-7.
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343.
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van Wijnen AJ, Wright KL, Massung RF, Gerretsen M, Stein JL, Stein GS. Two target sites for protein binding in the promoter region of a cell cycle regulated human H1 histone gene. Nucleic Acids Res. 1988 Jan 25; 16(2):571-92.
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344.
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Lawrence JB, Singer RH, Villnave CA, Stein JL, Stein GS. Intracellular distribution of histone mRNAs in human fibroblasts studied by in situ hybridization. Proc Natl Acad Sci U S A. 1988 Jan; 85(2):463-7.
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345.
|
Baumbach LL, Stein GS, Stein JL. Regulation of human histone gene expression: transcriptional and posttranscriptional control in the coupling of histone messenger RNA stability with DNA replication. Biochemistry. 1987 Sep 22; 26(19):6178-87.
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346.
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Helms SR, van Wijnen AJ, Kroeger P, Shiels A, Stewart C, Hirshman J, Stein JL, Stein GS. Identification of an enhancer-like element upstream from a cell cycle dependent human H4 histone gene. J Cell Physiol. 1987 Sep; 132(3):552-8.
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347.
|
Moreno ML, Stein GS, Stein JL. Nucleosomal organization of a BPV minichromosome containing a human H4 histone gene. Mol Cell Biochem. 1987 Apr; 74(2):173-7.
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348.
|
van Wijnen AJ, Stein JL, Stein GS. A nuclear protein with affinity for the 5' flanking region of a cell cycle dependent human H4 histone gene in vitro. Nucleic Acids Res. 1987 Feb 25; 15(4):1679-98.
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349.
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Lavin MF, Houldsworth J, Kumar S, Stein JL, Stein GS. Coupling of histone mRNA levels to radioresistant DNA synthesis in ataxia-telangiectasia cells. Mol Cell Biochem. 1987 Jan; 73(1):45-54.
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350.
|
Moreno ML, Chrysogelos SA, Stein GS, Stein JL. Reversible changes in the nucleosomal organization of a human H4 histone gene during the cell cycle. Biochemistry. 1986 Sep 23; 25(19):5364-70.
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351.
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Tripputi P, Emanuel BS, Croce CM, Green LG, Stein GS, Stein JL. Human histone genes map to multiple chromosomes. Proc Natl Acad Sci U S A. 1986 May; 83(10):3185-8.
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352.
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Marashi F, Croce CM, Stein JL, Stein GS. Selective expression of histone genes in mouse-human hybrid cells. Exp Cell Res. 1985 Aug; 159(2):280-6.
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353.
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Collart D, Stein GS, Stein JL. A series of repetitive DNA sequences are associated with human core and H1 histone genes. Mol Cell Biochem. 1985 Jul; 67(2):161-70.
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354.
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Banjar ZM, Briggs RC, Hnilica LS, Stein JL, Stein GS. Nuclear antigens in the HeLa cell cycle. Mol Cell Biochem. 1985 Jul; 67(2):101-10.
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355.
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Banjar ZM, Hnilica LS, Briggs RC, Dominguez E, Stein JL, Stein GS. cis-Diamminedichloroplatinum-mediated crosslinking of nuclear proteins to DNA is cell cycle specific. Arch Biochem Biophys. 1985 Feb 15; 237(1):202-7.
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356.
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Zwollo P, Stein GS, Stein JL. Variations in the organization of human genomic DNA segments containing H1 histone genes. Biochem Biophys Res Commun. 1984 Nov 14; 124(3):988-93.
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357.
|
Stein GS, Stein JL. Is human histone gene expression autogenously regulated? Mol Cell Biochem. 1984 Sep; 64(2):105-10.
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358.
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Flint SJ, Plumb MA, Yang UC, Stein GS, Stein JL. Effect of adenovirus infection on expression of human histone genes. Mol Cell Biol. 1984 Jul; 4(7):1363-71.
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359.
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Green LG, Stein JL, Stein GS. Influence of delta 9-tetrahydrocannabinol on expression of histone and ribosomal genes in normal and transformed human cells. Biochem Pharmacol. 1984 Apr 1; 33(7):1033-40.
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360.
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Marashi F, Green L, Briggs R, Duhl D, Hnilica L, Stein JL, Stein GS. Variations in the organization and expression of human histone genes in normal diploid and tumor cell lines. Anticancer Res. 1984 Jan-Apr; 4(1-2):69-74.
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361.
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Stein GS, Stein JL. Effects of cannabinoids on gene expression. NIDA Res Monogr. 1984; 44:5-24.
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362.
|
Green LG, Stein JL, Stein GS. A decreased influence of cannabinoids on macromolecular biosynthesis and cell proliferation in human cells which metabolize polycyclic hydrocarbon carcinogens. Anticancer Res. 1983 May-Jun; 3(3):211-7.
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363.
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Stein GS, Stein JL, Baumbach L, Leza A, Lichtler A, Marashi F, Plumb M, Rickles R, Sierra F, Van Dyke T. Organization and cell cycle regulation of human histone genes. Ann N Y Acad Sci. 1982 Dec 10; 397:148-67.
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364.
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Wojtkowiak Z, Duhl DM, Briggs RC, Hnilica LS, Stein JL, Stein GS. A nuclear matrix antigen HeLa and other human malignant cells. Cancer Res. 1982 Nov; 42(11):4546-52.
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365.
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Lichtler AC, Sierra F, Clark S, Wells JR, Stein JL, Stein GS. Multiple H4 histone mRNAs of HeLa cells are encoded in different genes. Nature. 1982 Jul 8; 298(5870):195-8.
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366.
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Shephard EA, Phillips I, Davis J, Stein JL, Stein GS. Evidence for the resumption of DNA replication prior to histone synthesis in HeLa cells after release from treatment with hydroxyurea. FEBS Lett. 1982 Apr 19; 140(2):189-92.
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367.
|
Marashi F, Baumbach L, Rickles R, Sierra F, Stein JL, Stein GS. Histone proteins in HeLa S3 cells are synthesized in a cell cycle stage specific manner. Science. 1982 Feb 5; 215(4533):683-5.
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368.
|
Sierra F, Leza A, Marashi F, Plumb M, Rickles R, Van Dyke T, Clark S, Wells J, Stein GS, Stein JL. Human histone genes are interspersed with members of the Alu family and with other transcribed sequences. Biochem Biophys Res Commun. 1982 Jan 29; 104(2):785-92.
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369.
|
Shephard EA, Jansing RL, Phillips IR, Stein JL, Stein GS. Representation of mRNA sequences in normal and SV40 transformed human diploid fibroblasts. Anticancer Res. 1981; 1(2):89-92.
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370.
|
Phillips IR, Shephard EA, Stein JL, Stein GS. Phosphorylation and dephosphorylation of chromosomal proteins during in vitro transcription. Cell Differ. 1981 Jan; 10(1):23-31.
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371.
|
Mon MJ, Haas AE, Stein JL, Stein GS. Influence of psychoactive and nonpsychoactive cannabinoids on chromatin structure and function in human cells. Biochem Pharmacol. 1981 Jan 1; 30(1):45-58.
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372.
|
Hochhauser SJ, Stein JL, Stein GS. Gene expression and cell cycle regulation. Int Rev Cytol. 1981; 71:95-243.
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373.
|
Stein GS, Stein JL, Marashi F, Parker MI, Sierra LF. Regulation of specific genes during the cell cycle. Utilization of homologous cDNAs and cloned sequences for studying histone gene expression in human cells. Cell Biophys. 1980 Dec; 2(4):291-314.
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374.
|
Lichtler AC, Detke S, Phillips IR, Stein GS, Stein JL. Multiple forms of H4 histone mRNA in human cells. Proc Natl Acad Sci U S A. 1980 Apr; 77(4):1942-6.
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375.
|
Detke S, Stein JL, Stein GS. Influence of chlorambucil, a bifunctional alkylating agent, on DNA replication and histone gene expression in HeLa S3 cells. Cancer Res. 1980 Apr; 40(4):967-74.
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376.
|
Thomson JA, Laipis PJ, Stein GS, Stein JL, Lander MR, Chattopadhyay SK. Regulation of endogenous type C viruses: evidence for transcriptional control of AKR viral expression. Virology. 1980 Mar; 101(2):529-33.
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377.
|
Phillips IR, Shephard EA, Stein JL, Kleinsmith LJ, Stein GS. Nuclear protein kinase activities during the cell cycle of HeLa S3 cells. Biochim Biophys Acta. 1979 Dec 17; 565(2):326-46.
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378.
|
Phillips IR, Shephard EA, Tatcher WB, Stein JL, Stein GS. Evidence for nonhistone chromosomal protein kinase activity associated with nucleosomes isolated from HeLa S3 cells. FEBS Lett. 1979 Oct 1; 106(1):56-62.
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379.
|
Stein GS, Stein JL, Park WD, Detkel S, Lichtler AC, Shephard EA, Jansing RL, Phillips IR. Regulation of histone gene expression in HeLa S3 cells. Arch Biol Med Exp (Santiago). 1979 Oct; 12(3):439-55.
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380.
|
Detke S, Stein JL, Stein GS. Synthesis of histone messenger RNAs by RNA polymerase II in nuclei from S phase HeLa S3 cells. Nucleic Acids Res. 1978 May; 5(5):1515-28.
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381.
|
Stein GS, Stein JL, Thomson JA. Chromosomal proteins in transformed and neoplastic cells: a review. Cancer Res. 1978 May; 38(5):1181-201.
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382.
|
Stein GS, Stein JL, Park WD, Detke S, Lichtler AC, Shephard EA, Jansing RL, Phillips IR. Regulation of histone gene expression in HeLa S3 cells. Cold Spring Harb Symp Quant Biol. 1978; 42 Pt 2:1107-20.
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383.
|
Lichtler AC, stein GS, Stein JL. Isolation and characterization of two mRNAs from HeLa S3 cells coding for histone H4. Biochem Biophys Res Commun. 1977 Aug 8; 77(3):845-53.
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384.
|
Stein JL, Stein GS, McGuire PM. Histone messenger RNA from HeLa cells: evidence for modified 5' termini. Biochemistry. 1977 May 17; 16(10):2207-13.
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385.
|
Jansing RL, Stein JL, Stein GS. Activation of histone gene transcription by nonhistone chromosomal proteins in WI-38 human diploid fibroblasts. Proc Natl Acad Sci U S A. 1977 Jan; 74(1):173-7.
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386.
|
Stein GS, Stein JL, Kleinsmith LJ, Jansing RL, Park WD, Thomson JA. Non-histone chromosomal proteins: their role in the regulation of histone-gene expression. Biochem Soc Symp. 1977; (42):137-63.
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387.
|
Stein GS, Stein JL, Kleinsmith LJ, Thomson JA, Park WD, Jansing RL. Role of nonhistone chromosomal proteins in the regulation of histone gene expression. Cancer Res. 1976 Nov; 36(11 Pt. 2):4307-18.
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388.
|
Thompson JA, Stein JL, Kleinsmith LJ, Stein GS. Activation of histone gene transcription by nonhistone chromosomal phosphoproteins. Science. 1976 Oct 22; 194(4263):428-31.
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389.
|
Park WD, Stein JL, Stein GS. Activation of in vitro histone gene transcription from Hela S3 chromatin by S-phase nonhistone chromosomal proteins. Biochemistry. 1976 Jul 27; 15(15):3296-30.
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390.
|
Stein JL, Reed K, Stein GS. Effect of histones and nonhistone chromosomal proteins on the transcription of histone genes from HeLaS3 cell DNA. Biochemistry. 1976 Jul 27; 15(15):3291-5.
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391.
|
Stein GS, Park WD, Stein JL, Lieberman MW. Synthesis of nuclear proteins during DNA repair synthesis in human diploid fibroblasts damaged with ultraviolet radiation of N-acetoxy-2-acetylaminofluroene. Proc Natl Acad Sci U S A. 1976 May; 73(5):1466-70.
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392.
|
Park WD, Thrall CL, Stein JL, Stein GS. Activation of histone gene transcription from chromatin of G1 HELA cells by S-phase non-histone chromosomal proteins. FEBS Lett. 1976 Feb 15; 62(2):226-9.
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393.
|
Stein JL, Thrall CL, Park WD, Mans RJ, Stein GS. Hybridization analysis of histone messenger RNA: association with polyribosomes during the cell cycle. Science. 1975 Aug 15; 189(4202):557-8.
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394.
|
Stein GS, Mans RJ, Gabbay EJ, Stein JL, Davis J, Adawadkar PD. Evidence for fidelity of chromatin reconstitution. Biochemistry. 1975 May 6; 14(9):1859-66.
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395.
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Stein GS, Park WD, Thrall CL, Mans RJ, Stein JL. Cell cycle stage-specific transcription of histone genes. Biochem Biophys Res Commun. 1975 Apr 21; 63(4):945-9.
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396.
|
Thrall CL, Park WD, Rashba HW, Stein JL, Mans RJ, Stein GS. In vitro synthesis of DNA complementary to polyadenylated histone messenger RNA. Biochem Biophys Res Commun. 1974 Dec 23; 61(4):1443-9.
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