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Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes.
Academic Article
Why?
TFEB-driven lysosomal biogenesis is pivotal for PGC1?a??-dependent renal stress resistance.
Academic Article
Why?
TFEB-driven lysosomal biogenesis is pivotal for PGC1a-dependent renal stress resistance.
Academic Article
Why?
TFEB-Mediated Pro-inflammatory Response in Murine Macrophages Induced by Acute Alpha7 Nicotinic Receptor Activation.
Academic Article
Why?
Nervous system control of intestinal host defense mediated by TFEB
Grant
Why?
A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS.
Academic Article
Why?
An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense.
Academic Article
Why?
Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.
Academic Article
Why?
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
Academic Article
Why?
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.
Academic Article
Why?
Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo.
Academic Article
Why?
HLH-30/TFEB-mediated autophagy functions in a cell-autonomous manner for epithelium intrinsic cellular defense against bacterial pore-forming toxin in C. elegans.
Academic Article
Why?
C. elegans orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB.
Academic Article
Why?
NHR-49/PPAR-a and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase.
Academic Article
Why?
PRMT-7/PRMT7 activates HLH-30/TFEB to guard plasma membrane integrity compromised by bacterial pore-forming toxins.
Academic Article
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