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Yan Hu PhD

TitleAssistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentProgram in Molecular Medicine
AddressBiotech II
373 Plantation Street, Suite 219
Worcester MA 01605-2377
Phone508-856-8129
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentProgram in Molecular Medicine


    Collapse Biography 
    Collapse education and training
    Qufu Normal University, Jining, , ChinaBS
    Wuhan University, Wuhan, , ChinaPHD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Durmaz E, Hu Y, Aroian RV, Klaenhammer TR. Intracellular and Extracellular Expression of Bacillus thuringiensis Crystal Protein Cry5B in Lactococcus lactis for Use as an Anthelminthic. Appl Environ Microbiol. 2015 Dec 18; 82(4):1286-94. PMID: 26682852.
      View in: PubMed
    2. Schwarz EM, Hu Y, Antoshechkin I, Miller MM, Sternberg PW, Aroian RV. Erratum: the genome and transcriptome of the zoonotic hookworm Ancylostoma ceylanicum identify infection-specific gene families. Nat Genet. 2015 Jun; 47(6):689. PMID: 26018900.
      View in: PubMed
    3. Wu CC, Hu Y, Miller M, Aroian RV, Sailor MJ. Protection and Delivery of Anthelmintic Protein Cry5B to Nematodes Using Mesoporous Silicon Particles. ACS Nano. 2015 Jun 23; 9(6):6158-67. PMID: 25950754.
      View in: PubMed
    4. Somvanshi VS, Ellis BL, Hu Y, Aroian RV. Nitazoxanide: nematicidal mode of action and drug combination studies. Mol Biochem Parasitol. 2014 Jan; 193(1):1-8. PMID: 24412397.
      View in: PubMed
    5. Hu Y, Ellis BL, Yiu YY, Miller MM, Urban JF, Shi LZ, Aroian RV. An extensive comparison of the effect of anthelmintic classes on diverse nematodes. PLoS One. 2013; 8(7):e70702. PMID: 23869246.
      View in: PubMed
    6. Hu Y, Miller MM, Derman AI, Ellis BL, Monnerat RG, Pogliano J, Aroian RV. Bacillus subtilis strain engineered for treatment of soil-transmitted helminth diseases. Appl Environ Microbiol. 2013 Sep; 79(18):5527-32. PMID: 23835175.
      View in: PubMed
    7. Urban JF, Hu Y, Miller MM, Scheib U, Yiu YY, Aroian RV. Bacillus thuringiensis-derived Cry5B has potent anthelmintic activity against Ascaris suum. PLoS Negl Trop Dis. 2013; 7(6):e2263. PMID: 23818995.
      View in: PubMed
    8. Hui F, Scheib U, Hu Y, Sommer RJ, Aroian RV, Ghosh P. Structure and glycolipid binding properties of the nematicidal protein Cry5B. Biochemistry. 2012 Dec 11; 51(49):9911-21. PMID: 23150986.
      View in: PubMed
    9. Hu Y, Zhan B, Keegan B, Yiu YY, Miller MM, Jones K, Aroian RV. Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms. PLoS Negl Trop Dis. 2012; 6(11):e1900. PMID: 23145203.
      View in: PubMed
    10. Hu Y, Aroian RV. Bacterial pore-forming proteins as anthelmintics. Invert Neurosci. 2012 Jun; 12(1):37-41. PMID: 22562659.
      View in: PubMed
    11. Kho MF, Bellier A, Balasubramani V, Hu Y, Hsu W, Nielsen-LeRoux C, McGillivray SM, Nizet V, Aroian RV. The pore-forming protein Cry5B elicits the pathogenicity of Bacillus sp. against Caenorhabditis elegans. PLoS One. 2011; 6(12):e29122. PMID: 22216181.
      View in: PubMed
    12. Balla KM, Lugo-Villarino G, Spitsbergen JM, Stachura DL, Hu Y, BaƱuelos K, Romo-Fewell O, Aroian RV, Traver D. Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants. Blood. 2010 Nov 11; 116(19):3944-54. PMID: 20713961.
      View in: PubMed
    13. Hu Y, Platzer EG, Bellier A, Aroian RV. Discovery of a highly synergistic anthelmintic combination that shows mutual hypersusceptibility. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):5955-60. PMID: 20231450.
      View in: PubMed
    14. Hu Y, Georghiou SB, Kelleher AJ, Aroian RV. Bacillus thuringiensis Cry5B protein is highly efficacious as a single-dose therapy against an intestinal roundworm infection in mice. PLoS Negl Trop Dis. 2010 Mar 02; 4(3):e614. PMID: 20209154.
      View in: PubMed
    15. Hu Y, Xiao SH, Aroian RV. The new anthelmintic tribendimidine is an L-type (levamisole and pyrantel) nicotinic acetylcholine receptor agonist. PLoS Negl Trop Dis. 2009; 3(8):e499. PMID: 19668355.
      View in: PubMed
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