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Ana L Maldonado-Contreras PhD

TitleAssistant Professor
Endowed TitleMarcellette G. Williams Scholar
InstitutionUMass Chan Medical School
DepartmentMicrobiology and Physiological Systems
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMicrobiology and Physiological Systems

    InstitutionT.H. Chan School of Medicine
    DepartmentPopulation and Quantitative Health Sciences

    InstitutionT.H. Chan School of Medicine
    DepartmentProgram in Microbial Dynamics

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentImmunology and Microbiology Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program


    Collapse Biography 
    Collapse education and training
    University of Zulia, Maracaibo, , VenezuelaBAEducation
    Instituto Universitario de Tecnologia, Caracas, , VenezuelaMSMicrobiology
    University of Puerto Rico, Cayey, PR, United StatesPHDMicrobiology
    Collapse awards and honors
    2013 - 2015Charles A. King Trust Postdoctoral Fellowship Program, The Medical Foundation Division
    2016 - 2019Research Scholar Award, American Gastroenterological Association
    2015 - 2020Faculty Diversity Scholar, Office of Faculty Affairs- UMMS

    Collapse Overview 
    Collapse Summary
    Focus: Gastrointestinal microbiome, diet-microbiome interaction

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Maldonado-Contreras A. Food as Treatment of Inflammatory Bowel Diseases. Infect Immun. 2022 05 19; 90(5):e0058321. PMID: 35323020.
      Citations: 1     Fields:    Translation:Humans
    2. Olendzki B, Bucci V, Cawley C, Maserati R, McManus M, Olednzki E, Madziar C, Chiang D, Ward DV, Pellish R, Foley C, Bhattarai S, McCormick BA, Maldonado-Contreras A. Dietary manipulation of the gut microbiome in inflammatory bowel disease patients: Pilot study. Gut Microbes. 2022 Jan-Dec; 14(1):2046244. PMID: 35311458.
      Citations:    Fields:    Translation:Humans
    3. Meza-Segura M, Birtley JR, Maldonado-Contreras A, Mueller C, Simin KJ, Stern LJ, McCormick BA. SepA Enhances Shigella Invasion of Epithelial Cells by Degrading Alpha-1 Antitrypsin and Producing a Neutrophil Chemoattractant. mBio. 2021 12 21; 12(6):e0283321. PMID: 34724811.
      Citations: 2     Fields:    Translation:HumansCells
    4. Foley SE, Tuohy C, Dunford M, Grey MJ, De Luca H, Cawley C, Szabady RL, Maldonado-Contreras A, Houghton JM, Ward DV, Mrsny RJ, McCormick BA. Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis. Microbiome. 2021 09 07; 9(1):183. PMID: 34493329.
      Citations: 1     Fields:    Translation:HumansAnimals
    5. Maldonado-Contreras A, Noel SE, Ward DV, Velez M, Mangano KM. Associations between Diet, the Gut Microbiome, and Short-Chain Fatty Acid Production among Older Caribbean Latino Adults. J Acad Nutr Diet. 2020 12; 120(12):2047-2060.e6. PMID: 32798072.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    6. Maldonado-Contreras A, Ferrer L, Cawley C, Crain S, Bhattarai S, Toscano J, Ward DV, Hoffman A. Dysbiosis in a canine model of human fistulizing Crohn's disease. Gut Microbes. 2020 11 09; 12(1):1785246. PMID: 32730134.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    7. Peter I, Maldonado-Contreras A, Eisele C, Frisard C, Simpson S, Nair N, Rendon A, Hawkins K, Cawley C, Debebe A, Tarassishin L, White S, Dubinsky M, Stone J, Clemente JC, Sabino J, Torres J, Hu J, Colombel JF, Olendzki B. A dietary intervention to improve the microbiome composition of pregnant women with Crohn's disease and their offspring: The MELODY (Modulating Early Life Microbiome through Dietary Intervention in Pregnancy) trial design. Contemp Clin Trials Commun. 2020 Jun; 18:100573. PMID: 32617430.
      Citations:    
    8. Zhao M, Chiriboga D, Olendzki B, Xie B, Li Y, McGonigal LJ, Maldonado-Contreras A, Ma Y. Substantial Increase in Compliance with Saturated Fatty Acid Intake Recommendations after One Year Following the American Heart Association Diet. Nutrients. 2018 Oct 12; 10(10). PMID: 30322012.
      Citations: 3     Fields:    Translation:Humans
    9. Maldonado-Contreras A, Birtley JR, Boll E, Zhao Y, Mumy KL, Toscano J, Ayehunie S, Reinecker HC, Stern LJ, McCormick BA. Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation. Gut Microbes. 2017 11 02; 8(6):544-560. PMID: 28598765.
      Citations: 17     Fields:    Translation:HumansCells
    10. Maldonado-Contreras A, Gerstein RM. Editorial: No Trp, no B: surprising connectivity of diet, microbiome, aging, and adaptive immunity. J Leukoc Biol. 2017 04; 101(4):807-809. PMID: 28366880.
      Citations: 1     Fields:    Translation:Humans
    11. Maldonado-Contreras A, Mane SP, Zhang XS, Pericchi L, Alarcón T, Contreras M, Linz B, Blaser MJ, Domínguez-Bello MG. Phylogeographic evidence of cognate recognition site patterns and transformation efficiency differences in H. pylori: theory of strain dominance. BMC Microbiol. 2013 Sep 19; 13:211. PMID: 24050390.
      Citations: 2     Fields:    Translation:HumansCells
    12. Maldonado-Contreras AL, McCormick BA. Intestinal epithelial cells and their role in innate mucosal immunity. Cell Tissue Res. 2011 Jan; 343(1):5-12. PMID: 21104188.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    13. Srikanth CV, Wall DM, Maldonado-Contreras A, Shi H, Zhou D, Demma Z, Mumy KL, McCormick BA. Salmonella pathogenesis and processing of secreted effectors by caspase-3. Science. 2010 Oct 15; 330(6002):390-393. PMID: 20947770.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    14. Maldonado-Contreras A, Goldfarb KC, Godoy-Vitorino F, Karaoz U, Contreras M, Blaser MJ, Brodie EL, Dominguez-Bello MG. Structure of the human gastric bacterial community in relation to Helicobacter pylori status. ISME J. 2011 Apr; 5(4):574-9. PMID: 20927139.
      Citations: 113     Fields:    Translation:HumansCells
    15. Mane SP, Dominguez-Bello MG, Blaser MJ, Sobral BW, Hontecillas R, Skoneczka J, Mohapatra SK, Crasta OR, Evans C, Modise T, Shallom S, Shukla M, Varon C, Mégraud F, Maldonado-Contreras AL, Williams KP, Bassaganya-Riera J. Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses. J Bacteriol. 2010 Jun; 192(12):3078-92. PMID: 20400544.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    16. Marini E, Maldonado-Contreras AL, Cabras S, Hidalgo G, Buffa R, Marin A, Floris G, Racugno W, Pericchi LR, Castellanos ME, Gröschl M, Blaser MJ, Domínguez-Bello MG. Helicobacter pylori and intestinal parasites are not detrimental to the nutritional status of Amerindians. Am J Trop Med Hyg. 2007 Mar; 76(3):534-40. PMID: 17360880.
      Citations: 12     Fields:    Translation:HumansCells
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