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Robert J Nicolosi BS, MS, PhD

TitleAdjunct Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMedicine
AddressUniversity of Massachusetts Lowell
3 Solomont Way, Suite 4
Lowell MA 01854
Phone508-934-4501
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMedicine
    DivisionCardiovascular Medicine


    Collapse Biography 
    Collapse education and training
    Saint Anselm College, Manchester, NH, United StatesBSBiology
    University of New Hampshire Durham, Durham, NH, United StatesMSZoology
    University of New Hampshire Durham, Durham, NH, United StatesPH DZoology/Biochemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Ockene IS, Tellez TL, Rosal MC, Reed GW, Mordes J, Merriam PA, Olendzki BC, Handelman G, Nicolosi R, Ma Y. Outcomes of a Latino community-based intervention for the prevention of diabetes: the Lawrence Latino Diabetes Prevention Project. Am J Public Health. 2012 Feb; 102(2):336-42. PMID: 22390448.
      View in: PubMed
    2. Kakumanu S, Tagne JB, Wilson TA, Nicolosi RJ. A nanoemulsion formulation of dacarbazine reduces tumor size in a xenograft mouse epidermoid carcinoma model compared to dacarbazine suspension. Nanomedicine. 2011 Jun; 7(3):277-83. PMID: 21215333.
      View in: PubMed
    3. Vishwanathan R, Gendron CM, Goodrow-Kotyla EF, Wilson TA, Nicolosi RJ. Increased consumption of dietary cholesterol, lutein, and zeaxanthin as egg yolks does not decrease serum concentrations and lipoprotein distribution of other carotenoids, retinol, and tocopherols. Nutr Res. 2010 Nov; 30(11):747-55. PMID: 21130293.
      View in: PubMed
    4. Edmund AR, Kambalapally S, Wilson TA, Nicolosi RJ. Encapsulation of cadmium selenide quantum dots using a self-assembling nanoemulsion (SANE) reduces their in vitro toxicity. Toxicol In Vitro. 2011 Feb; 25(1):185-90. PMID: 21044677.
      View in: PubMed
    5. Vishwanathan R, Goodrow-Kotyla EF, Wooten BR, Wilson TA, Nicolosi RJ. Consumption of 2 and 4 egg yolks/d for 5 wk increases macular pigment concentrations in older adults with low macular pigment taking cholesterol-lowering statins. Am J Clin Nutr. 2009 Nov; 90(5):1272-9. PMID: 19759170.
      View in: PubMed
    6. Tagne JB, Kakumanu S, Nicolosi RJ. Nanoemulsion preparations of the anticancer drug dacarbazine significantly increase its efficacy in a xenograft mouse melanoma model. Mol Pharm. 2008 Nov-Dec; 5(6):1055-63. PMID: 19434855.
      View in: PubMed
    7. Kuo F, Subramanian B, Kotyla T, Wilson TA, Yoganathan S, Nicolosi RJ. Nanoemulsions of an anti-oxidant synergy formulation containing gamma tocopherol have enhanced bioavailability and anti-inflammatory properties. Int J Pharm. 2008 Nov 3; 363(1-2):206-13. PMID: 18718513.
      View in: PubMed
    8. Subramanian B, Kuo F, Ada E, Kotyla T, Wilson T, Yoganathan S, Nicolosi R. Enhancement of anti-inflammatory property of aspirin in mice by a nano-emulsion preparation. Int Immunopharmacol. 2008 Nov; 8(11):1533-9. PMID: 18625344.
      View in: PubMed
    9. Tagne JB, Kakumanu S, Ortiz D, Shea T, Nicolosi RJ. A nanoemulsion formulation of tamoxifen increases its efficacy in a breast cancer cell line. Mol Pharm. 2008 Mar-Apr; 5(2):280-6. PMID: 18171014.
      View in: PubMed
    10. Kuo F, Kotyla T, Wilson T, Kifle L, Panagiotou T, Gruverman I, Tagne JB, Shea T, Nicolosi R. A nanoemulsion of an anti-oxidant synergy formulation reduces tumor growth rate in neuroblastoma-bearing nude mice. J Exp Ther Oncol. 2007; 6(2):129-35. PMID: 17407971.
      View in: PubMed
    11. Wenzel AJ, Gerweck C, Barbato D, Nicolosi RJ, Handelman GJ, Curran-Celentano J. A 12-wk egg intervention increases serum zeaxanthin and macular pigment optical density in women. J Nutr. 2006 Oct; 136(10):2568-73. PMID: 16988128.
      View in: PubMed
    12. Goodrow EF, Wilson TA, Houde SC, Vishwanathan R, Scollin PA, Handelman G, Nicolosi RJ. Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrations. J Nutr. 2006 Oct; 136(10):2519-24. PMID: 16988120.
      View in: PubMed
    13. Wilson TA, Nicolosi RJ, Woolfrey B, Kritchevsky D. Rice bran oil and oryzanol reduce plasma lipid and lipoprotein cholesterol concentrations and aortic cholesterol ester accumulation to a greater extent than ferulic acid in hypercholesterolemic hamsters. J Nutr Biochem. 2007 Feb; 18(2):105-12. PMID: 16713234.
      View in: PubMed
    14. Wilson TA, Kritchevsky D, Kotyla T, Nicolosi RJ. Structured triglycerides containing caprylic (8:0) and oleic (18:1) fatty acids reduce blood cholesterol concentrations and aortic cholesterol accumulation in hamsters. Biochim Biophys Acta. 2006 Mar; 1761(3):345-9. PMID: 16580874.
      View in: PubMed
    15. Wilson TA, Nicolosi RJ, Saati A, Kotyla T, Kritchevsky D. Conjugated linoleic acid isomers reduce blood cholesterol levels but not aortic cholesterol accumulation in hypercholesterolemic hamsters. Lipids. 2006 Jan; 41(1):41-8. PMID: 16555470.
      View in: PubMed
    16. Wilson TA, Nicolosi RJ, Kotyla T, Sundram K, Kritchevsky D. Different palm oil preparations reduce plasma cholesterol concentrations and aortic cholesterol accumulation compared to coconut oil in hypercholesterolemic hamsters. J Nutr Biochem. 2005 Oct; 16(10):633-40. PMID: 16081272.
      View in: PubMed
    17. Ausman LM, Rong N, Nicolosi RJ. Hypocholesterolemic effect of physically refined rice bran oil: studies of cholesterol metabolism and early atherosclerosis in hypercholesterolemic hamsters. J Nutr Biochem. 2005 Sep; 16(9):521-9. PMID: 16115540.
      View in: PubMed
    18. Ma Y, Chiriboga D, Olendzki BC, Nicolosi R, Merriam PA, Ockene IS. Effect of soy protein containing isoflavones on blood lipids in moderately hypercholesterolemic adults: a randomized controlled trial. J Am Coll Nutr. 2005 Aug; 24(4):275-85. PMID: 16093405.
      View in: PubMed
    19. Shea TB, Ortiz D, Nicolosi RJ, Kumar R, Watterson AC. Nanosphere-mediated delivery of vitamin E increases its efficacy against oxidative stress resulting from exposure to amyloid beta. J Alzheimers Dis. 2005 Aug; 7(4):297-301. PMID: 16131731.
      View in: PubMed
    20. Binkoski AE, Kris-Etherton PM, Wilson TA, Mountain ML, Nicolosi RJ. Balance of unsaturated fatty acids is important to a cholesterol-lowering diet: comparison of mid-oleic sunflower oil and olive oil on cardiovascular disease risk factors. J Am Diet Assoc. 2005 Jul; 105(7):1080-6. PMID: 15983524.
      View in: PubMed
    21. Wilson TA, Nicolosi RJ, Delaney B, Chadwell K, Moolchandani V, Kotyla T, Ponduru S, Zheng GH, Hess R, Knutson N, Curry L, Kolberg L, Goulson M, Ostergren K. Reduced and high molecular weight barley beta-glucans decrease plasma total and non-HDL-cholesterol in hypercholesterolemic Syrian golden hamsters. J Nutr. 2004 Oct; 134(10):2617-22. PMID: 15465756.
      View in: PubMed
    22. Kumar R, Chen MH, Parmar VS, Samuelson LA, Kumar J, Nicolosi R, Yoganathan S, Watterson AC. Supramolecular assemblies based on copolymers of PEG600 and functionalized aromatic diesters for drug delivery applications. J Am Chem Soc. 2004 Sep 1; 126(34):10640-4. PMID: 15327322.
      View in: PubMed
    23. Nicolosi RJ, Woolfrey B, Wilson TA, Scollin P, Handelman G, Fisher R. Decreased aortic early atherosclerosis and associated risk factors in hypercholesterolemic hamsters fed a high- or mid-oleic acid oil compared to a high-linoleic acid oil. J Nutr Biochem. 2004 Sep; 15(9):540-7. PMID: 15350986.
      View in: PubMed
    24. Kritchevsky D, Tepper SA, Wright S, Czarnecki SK, Wilson TA, Nicolosi RJ. Conjugated linoleic acid isomer effects in atherosclerosis: growth and regression of lesions. Lipids. 2004 Jul; 39(7):611-6. PMID: 15588017.
      View in: PubMed
    25. Ockene IS, Chiriboga DE, Stanek EJ, Harmatz MG, Nicolosi R, Saperia G, Well AD, Freedson P, Merriam PA, Reed G, Ma Y, Matthews CE, Hebert JR. Seasonal variation in serum cholesterol levels: treatment implications and possible mechanisms. Arch Intern Med. 2004 Apr 26; 164(8):863-70. PMID: 15111372.
      View in: PubMed
    26. Alexaki A, Wilson TA, Atallah MT, Handelman G, Nicolosi RJ. Hamsters fed diets high in saturated fat have increased cholesterol accumulation and cytokine production in the aortic arch compared with cholesterol-fed hamsters with moderately elevated plasma non-HDL cholesterol concentrations. J Nutr. 2004 Feb; 134(2):410-5. PMID: 14747681.
      View in: PubMed
    27. Volicer BJ, Quattrocchi N, Candelieri R, Nicolosi R. Health and weight perceptions of obese students. Nurse Pract. 2003 Nov; 28(11):13-4. PMID: 14657737.
      View in: PubMed
    28. Wilson TA, Foxall TL, Nicolosi RJ. Doxazosin, an alpha-1 antagonist, prevents further progression of the advanced atherosclerotic lesion in hypercholesterolemic hamsters. Metabolism. 2003 Oct; 52(10):1240-5. PMID: 14564673.
      View in: PubMed
    29. Handelman GJ, Rosales LM, Barbato D, Luscher J, Adhikarla R, Nicolosi RJ, Finkelstein FO, Ronco C, Kaysen GA, Hoenich NA, Levin NW. Breath ethane in dialysis patients and control subjects. Free Radic Biol Med. 2003 Jul 1; 35(1):17-23. PMID: 12826252.
      View in: PubMed
    30. Yoganathan S, Nicolosi R, Wilson T, Handelman G, Scollin P, Tao R, Binford P, Orthoefer F. Antagonism of croton oil inflammation by topical emu oil in CD-1 mice. Lipids. 2003 Jun; 38(6):603-7. PMID: 12934669.
      View in: PubMed
    31. Delaney B, Nicolosi RJ, Wilson TA, Carlson T, Frazer S, Zheng GH, Hess R, Ostergren K, Haworth J, Knutson N. Beta-glucan fractions from barley and oats are similarly antiatherogenic in hypercholesterolemic Syrian golden hamsters. J Nutr. 2003 Feb; 133(2):468-75. PMID: 12566485.
      View in: PubMed
    32. Shea TB, Rogers E, Ashline D, Ortiz D, Duarte N, Wilson TO, Nicolosi RJ, Sheu MS. Vitamin E deficiency does not induce compensatory antioxidant increases in central nervous system tissue of apolipoprotein E-deficient mice. J Alzheimers Dis. 2003 Feb; 5(1):9-14. PMID: 12590161.
      View in: PubMed
    33. Kritchevsky D, Tepper SA, Wright S, Czarnecki SK, Wilson TA, Nicolosi RJ. Cholesterol vehicle in experimental atherosclerosis 24: avocado oil. J Am Coll Nutr. 2003 Feb; 22(1):52-5. PMID: 12569114.
      View in: PubMed
    34. Reece SM, Holcroft C, Faul M, Quattrocchi N, Nicolosi R. A look at asthma care in a university setting. Nurse Pract. 2002 Dec; 27(12):35-42. PMID: 12493948.
      View in: PubMed
    35. Shea TB, Ekinci FJ, Ortiz D, Dawn-Linsley M, Wilson TO, Nicolosi RJ. Efficacy of vitamin E, phosphatidyl choline, and pyruvate on buffering neuronal degeneration and oxidative stress in cultured cortical neurons and in central nervous tissue of apolipoprotein E-deficient mice. Free Radic Biol Med. 2002 Jul 15; 33(2):276-82. PMID: 12106823.
      View in: PubMed
    36. Nicolosi RJ, Wilson TA, Handelman G, Foxall T, Keaney JF, Vita JA. Decreased aortic early atherosclerosis in hypercholesterolemic hamsters fed oleic acid-rich TriSun oil compared to linoleic acid-rich sunflower oil. J Nutr Biochem. 2002 Jul; 13(7):392-402. PMID: 12121826.
      View in: PubMed
    37. Nicolosi RJ, Wilson TA, Lawton C, Handelman GJ. Dietary effects on cardiovascular disease risk factors: beyond saturated fatty acids and cholesterol. J Am Coll Nutr. 2001 Oct; 20(5 Suppl):421S-427S; discussion 440S-442S. PMID: 11603652.
      View in: PubMed
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