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Paulo Martins MD, PhD, FAST, FEBS, FACS

TitleAssociate Professor
InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
55 Lake Avenue North S6-412
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DivisionOrgan Transplantation

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentTranslational Science

    Collapse Biography 
    Collapse education and training
    Federal University of Bahia, Salvador, , BrazilMDMedicine
    University of Medicine Berlin, Berlin, , GermanyPHD
    Collapse awards and honors
    2020AOA Honored membership, Alpha Omega Alpha Honor Society
    2020Prize for Academic Collaboration and Excellence, University of Massachusetts-UMass Memorial Hospital
    2020ASTS Mid-Level Faculty Grant, American Society of Transplantation (ASTS)
    2019Basic Science Career Development, American Society of Transplantation (AST)
    2018Rising star Award, American Society of Transplant Surgeons (ASTS)
    2018Fellow, European Board of Surgery (FEBS)
    2018Rising star Award, International Liver Transplant Society (ILTS)
    2017Fellow of The American College of Surgeons (FACS), American College of Surgeons
    2017Poster of distinction, American College of Surgeons annual meeting
    2015Fellow of American Society of Transplantation, American Society of Transplantation
    2015Vanguard Award, American Society of Transplant Surgeons
    2014Poster distinction, World Transplant Congress -ASTS/AST
    2014Faculty Development Award, University of Massachusetts
    2013John Healey Research Award , University of Massachusetts
    2009Distinguished Fellow, American Society of Transplantation
    2005AST/ESOT Research Award , Brigham and Women’s Hospital. Transplant Research Center. Harvard Medical School
    2005Best Poster Prize, German Transplantation Congress (DTG)
    2004Wolfgang-Müller-Osten Award, German Society of Surgery
    2004Ernst Von Leiden Scholarship, Berlin Cancer Society
    2004Henk Shippers Award” – Young investigator , Eurotransplant International Foundation
    2003Best Poster Award, Congress of the European Society of Transplantation
    2003“Emil Sabbaga Award” for the best oral , Portuguese-Brazilian Transplantation Congress
    2002Award for the best oral presentation in the session “Transplant/Biomaterials” , 13th European Student Congress Berlin
    20024th Prize at the European Students Conference (ESC). , Berlin-Germany
    2002German Academic Exchange Service (DAAD) PhD scholarship, Charité - Berlin University-Germany.
    1992Ranked first in the University Admission Exam, Federal University of Bahia, Brazil

    Collapse Overview 
    Collapse overview

    Professional Experience

    2001-2005: PhD, Transplant immunology, University of Berlin-Germany
    2005-2008: Post-doc research fellowship, Harvard University
    2008-2010: Hepatobiliary and Transplantation Surgery Fellowship,  New York Medical College
    2010-2012: Transplantation Surgery Fellowship, Mass General Hospital, Harvard University
    1/2012-3/2013: Instructor in Surgery, Massachusetts General Hospital, Harvard University
    3/2013-current: Assistant Professor/Transplant Surgeon, University of Massachusetts

    My research interest is on transplant immunobiology, especially on  Ischemia Reperfusion Injury, and Immunosenescence. Clinically, my research interest is on Transplant Outcome Research, more especifically on the use of  Extended Criteria Donors .

    Currently, I am looking for a qualified post-doc to work on a project on liver machine preservation using rodent models. Experience with immunological assays and microsurgery is expected.

    Collapse Rotation Projects

    Graft Treatment during Machine Perfusion Preservation

    Collapse Post Docs

    Julianna Buchwald (MD,PhD cand.)

    Isabel Bruggenwirt (MD, PhD cand))

    Jing Xu (UMass med student)

    Cristine Yao (UMass med student)

    Jessica Perry (past postdoc)

    Andrew Gillooly MD (past postdoc)

    Caroline Moore PhD (past postdoc)

    Hazel Briner MD (past postdoc)

    Sarah Sheppard MD (past postdoc)

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Jiang D, Ji T, Liu W, Bednarsch J, Selzner M, Pratschke J, Lurje G, Cao T, Brüggenwirth IMA, Martins PN, Arke Lang S, Peter Neumann U, Czigany Z. Four Decades of Clinical Liver Transplantation Research: Results of a Comprehensive Bibliometric Analysis. Transplantation. 2022 10 01; 106(10):1897-1908. PMID: 35831925.
      Citations:    Fields:    
    2. Kim IK, Martins PN, Pavlakis M, Eneanya ND, Patzer RE. Past and Present Policy Efforts in Achieving Racial Equity in Kidney Transplantation. Curr Transplant Rep. 2022; 9(2):114-118. PMID: 35646512.
    3. Bonaccorsi-Riani E, Gillooly AR, Iesari S, Brüggenwirth IMA, Ferguson CM, Komuta M, Xhema D, Daumerie A, Maistriaux L, Leuvenink H, Kupiec-Weglinski J, Porte RJ, Khvorova A, Cave DR, Gianello P, Martins PN. Delivering siRNA Compounds During HOPE to Modulate Organ Function: A Proof-of-concept Study in a Rat Liver Transplant Model. Transplantation. 2022 08 01; 106(8):1565-1576. PMID: 35581683.
      Citations:    Fields:    Translation:HumansAnimals
    4. Martins PN, Pavlakis M, Diez A. New Equations for Estimating the GFR without Race. N Engl J Med. 2022 04 28; 386(17):1670. PMID: 35476658.
      Citations:    Fields:    Translation:Humans
    5. Del Turco S, Cappello V, Tapeinos C, Moscardini A, Sabatino L, Battaglini M, Melandro F, Torri F, Martinelli C, Babboni S, Silvestrini B, Morganti R, Gemmi M, De Simone P, Martins PN, Crocetti L, Peris A, Campani D, Basta G, Ciofani G, Ghinolfi D. Cerium oxide nanoparticles administration during machine perfusion of discarded human livers: A pilot study. Liver Transpl. 2022 07; 28(7):1173-1185. PMID: 35100468.
      Citations:    Fields:    Translation:Humans
    6. Liu J, Martins PN, Bhat M, Pang L, Yeung OW, Ng KT, Spiro M, Raptis DA, Man K, Mas VR. Biomarkers and predictive models of early allograft dysfunction in liver transplantation - A systematic review of the literature, meta-analysis and expert panel recommendations. Clin Transplant. 2022 Mar 15; e14635. PMID: 35291044.
      Citations:    Fields:    
    7. Martins PN, Schlegel A, Ghinolfi D. Cold or Not So Cold?-Static Organ Preservation at 10 °C May Prolong Organ Preservation and Facilitate Transplant Logistics. Transplantation. 2022 03 01; 106(3):427-429. PMID: 35192581.
      Citations: 1     Fields:    
    8. Patzer RE, Adler JT, Harding JL, Huml A, Kim I, Ladin K, Martins PN, Mohan S, Ross-Driscoll K, Pastan SO. A Population Health Approach to Transplant Access: Challenging the Status Quo. Am J Kidney Dis. 2022 Sep; 80(3):406-415. PMID: 35227824.
      Citations:    Fields:    
    9. Czigany Z, Brüggenwirth IMA, Ekser B, Abdelrahim M, Bhat M, Bonaccorsi-Riani E, Chen A, Emamaullee J, Eymard C, Ho CM, Mas VR, Zarrinpar A, Yuksel M, Martins PN, Selzner M. What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2020-2021?-Report of the Basic and Translational Research Committee of the International Liver Transplantation Society. Transplantation. 2022 02 01; 106(2):227-233. PMID: 34856600.
      Citations: 1     Fields:    
    10. Weissenbacher A, Lindstedt S, Martins PN. Machine preservation highlights from the congress of the European Society of Organ Transplantation 2021. Artif Organs. 2022 Feb; 46(2):321-326. PMID: 35014720.
      Citations:    Fields:    Translation:Humans
    11. Buchwald JE, Martins PN. Designer organs: The future of personalized transplantation. Artif Organs. 2022 Feb; 46(2):180-190. PMID: 35014719.
      Citations:    Fields:    Translation:HumansAnimals
    12. Boteon YL, Hessheimer AJ, Brüggenwirth IMA, Boteon APCS, Padilla M, de Meijer VE, Domínguez-Gil B, Porte RJ, Perera MTPR, Martins PN. The economic impact of machine perfusion technology in liver transplantation. Artif Organs. 2022 Feb; 46(2):191-200. PMID: 34878658.
      Citations: 1     Fields:    Translation:Humans
    13. Martins PN, Clavien PA. Comment on "Making Every Liver Count Increased Transplant Yield of Donor Livers Through Normothermic Machine Perfusion". Ann Surg. 2021 12 01; 274(6):e839-e841. PMID: 33351486.
      Citations:    Fields:    Translation:Humans
    14. Kim E, Adeel A, Bozorgzadeh A, Amano S, Barry CT, Daly JS, Devuni D, Elaba Z, Houk L, Martins PN, Movahedi B, Ramanathan M, Theodoropoulos NM. Treatment of Acute Graft-versus-Host Disease in Liver Transplant Recipients. Case Rep Transplant. 2021; 2021:8981429. PMID: 34888111.
    15. Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score. Br J Surg. 2021 Nov 11; 108(11):1274-1292. PMID: 34227657.
      Citations: 3     Fields:    Translation:HumansCells
    16. Pavan-Guimaraes J, Zarrinpar A, Beduschi T, Atkinson C, Martins PN. Machine perfusion organ preservation: Highlights from the American Transplant Congress 2021. Artif Organs. 2022 Feb; 46(2):315-320. PMID: 34755348.
      Citations:    Fields:    Translation:Humans
    17. Valbuena VSM, Obayemi JE, Purnell TS, Scantlebury VP, Olthoff KM, Martins PN, Higgins RS, Blackstock DM, Dick AAS, Watkins AC, Englesbe MJ, Simpson DC. Gender and racial disparities in the transplant surgery workforce. Curr Opin Organ Transplant. 2021 10 01; 26(5):560-566. PMID: 34524181.
      Citations: 1     Fields:    Translation:Humans
    18. McClinton A, Gullo J, Martins PN, Serrano OK. Access to liver transplantation for minority populations in the United States. Curr Opin Organ Transplant. 2021 10 01; 26(5):508-512. PMID: 34354000.
      Citations:    Fields:    Translation:Humans
    19. Martins PN, Kim IK. Editorial: Disparities in transplantation access and outcomes: mind the gap! Curr Opin Organ Transplant. 2021 10 01; 26(5):498-500. PMID: 34402456.
      Citations:    Fields:    Translation:Humans
    20. SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. Br J Surg. 2021 Sep 27; 108(9):1056-1063. PMID: 33761533.
      Citations: 131     Fields:    Translation:HumansCellsPHPublic Health
    21. Boteon YL, Martins PN, Muiesan P, Schlegel A. Machine perfusion of the liver: Putting the puzzle pieces together. World J Gastroenterol. 2021 Sep 14; 27(34):5727-5736. PMID: 34629797.
      Citations: 2     Fields:    Translation:Humans
    22. Ghinolfi D, Jassem W, Martins PN. Ischemia-free liver transplantation. Is this the right answer to overpass organ shortage and post-liver transplant complications? Lancet Reg Health West Pac. 2021 Nov; 16:100263. PMID: 34590065.
    23. SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia. 2022 Jan; 77(1):28-39. PMID: 34428858.
      Citations: 15     Fields:    Translation:HumansCells
    24. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia. 2021 11; 76(11):1454-1464. PMID: 34371522.
      Citations: 10     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    25. Lei B, Sleiman MM, Cheng Q, Tu Z, Zhu P, Goddard M, Martins PN, Langerude L, Nadig S, Tomlinson S, Atkinson C. In Situ Pre-Treatment of Vascularized Composite Allografts With a Targeted Complement Inhibitor Protects Against Brain Death and Ischemia Reperfusion Induced Injuries. Front Immunol. 2021; 12:630581. PMID: 34394069.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    26. Brüggenwirth IMA, van Leeuwen OB, Porte RJ, Martins PN. The Emerging Role of Viability Testing During Liver Machine Perfusion. Liver Transpl. 2022 05; 28(5):876-886. PMID: 33963657.
      Citations: 2     Fields:    Translation:Humans
    27. Martins PN, Clavien PA, Jalan R, Ghinolfi D. A Call for Randomization in Clinical Trials of Liver Machine Perfusion Preservation. Hepatology. 2021 06; 73(6):2586-2591. PMID: 33336391.
      Citations: 1     Fields:    Translation:Humans
    28. Bonaccorsi-Riani E, Gillooly A, Brüggenwirth IMA, Martins PN. Delivery of genetic load during ex situ liver machine perfusion with potential for CRISPR-Cas9 gene editing: An innovative strategy for graft treatment. Hepatobiliary Pancreat Dis Int. 2021 Oct; 20(5):503-505. PMID: 33958293.
      Citations: 1     Fields:    Translation:Humans
    29. Martins PN, Rizzari MD, Ghinolfi D, Jochmans I, Attia M, Jalan R, Friend PJ. Design, Analysis, and Pitfalls of Clinical Trials Using Ex Situ Liver Machine Perfusion: The International Liver Transplantation Society Consensus Guidelines. Transplantation. 2021 04 01; 105(4):796-815. PMID: 33760791.
      Citations: 5     Fields:    Translation:Humans
    30. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia. 2021 06; 76(6):748-758. PMID: 33690889.
      Citations: 82     Fields:    Translation:HumansCells
    31. Ziogas IA, Martins PN, Alexopoulos SP, Matsuoka LK, Rauf MA, Geevarghese SK, Gorden LD, Karp SJ, Perkins JD, Montenovo MI. Effect of Donor Transaminase Levels on Graft Survival Following Liver Transplant: An Analysis of the Organ Procurement and Transplantation Network Database. Exp Clin Transplant. 2021 03; 19(3):250-258. PMID: 33605200.
      Citations:    Fields:    Translation:Humans
    32. Martins PN, Buchwald JE, Movahedi B, Torres U, Emhoff T, Walker J, DeBusk MG, Bozorgzadeh A. Successful treatment of complete traumatic transection of the suprahepatic inferior vena cava with veno-venous and cardiopulmonary bypass with hypothermic circulatory arrest. Hepatobiliary Pancreat Dis Int. 2021 Dec; 20(6):601-610. PMID: 33468417.
      Citations:    Fields:    Translation:Humans
    33. Navarro MED, Yao CC, Whiteley A, Movahedi B, Devuni D, Barry C, Zacharias I, Theodoropoulos NM, Bozorgzadeh A, Martins PN. Liver transplant evaluation for fulminant liver failure due to acute hepatitis A infection: Case series and literature review. Transpl Infect Dis. 2021 Apr; 23(2):e13476. PMID: 32989849.
      Citations: 3     Fields:    Translation:Humans
    34. Brüggenwirth IMA, de Meijer VE, Porte RJ, Martins PN. Viability criteria assessment during liver machine perfusion. Nat Biotechnol. 2020 11; 38(11):1260-1262. PMID: 33106683.
      Citations: 5     Fields:    Translation:Humans
    35. Brüggenwirth IMA, van Leeuwen OB, Müller M, Dutkowski P, Monbaliu D, Martins PN, Porte RJ, de Meijer VE. The importance of adequate oxygenation during hypothermic machine perfusion. JHEP Rep. 2021 Feb; 3(1):100194. PMID: 33305200.
    36. Xu J, Buchwald JE, Martins PN. Review of Current Machine Perfusion Therapeutics for Organ Preservation. Transplantation. 2020 09; 104(9):1792-1803. PMID: 32371846.
      Citations: 11     Fields:    Translation:HumansAnimals
    37. Roubil JG, Martins PN, Babak M, Bledsoe J, Bludevich BM, Barry C, Bozorgzadeh A. Resolution of Severe Graft Steatosis Before Living-Donor Liver Transplant After 86 Pounds of Weight Loss. Exp Clin Transplant. 2022 09; 20(9):874-877. PMID: 32778015.
      Citations:    Fields:    
    38. Brüggenwirth IMA, Porte RJ, Martins PN. Bile Composition as a Diagnostic and Prognostic Tool in Liver Transplantation. Liver Transpl. 2020 09; 26(9):1177-1187. PMID: 32246581.
      Citations: 3     Fields:    Translation:Humans
    39. van Leeuwen OB, Brüggenwirth IMA, Porte RJ, Martins PN. Development of a machine perfusion device for cold-to-warm machine perfusion. HPB (Oxford). 2020 09; 22(9):1368-1369. PMID: 32646807.
      Citations:    Fields:    Translation:Humans
    40. Theodoropoulos NM, Bolstorff B, Bozorgzadeh A, Brandeburg C, Cumming M, Daly JS, Ellison RT, Forsberg K, Gade L, Gibson L, Greenough T, Litvintseva AP, Mack DA, Madoff L, Martins PN, McHale E, Melvin Z, Movahedi B, Stiles T, Vallabhaneni S, Levitz SM. Candida auris outbreak involving liver transplant recipients in a surgical intensive care unit. Am J Transplant. 2020 12; 20(12):3673-3679. PMID: 32530145.
      Citations: 7     Fields:    Translation:HumansAnimalsPHPublic Health
    41. Martins PN, Buchwald JE, Mergental H, Vargas L, Quintini C. The role of normothermic machine perfusion in liver transplantation. Int J Surg. 2020 Oct; 82S:52-60. PMID: 32417462.
      Citations: 7     Fields:    Translation:Humans
    42. Dickson KM, Martins PN. Implications of liver donor age on ischemia reperfusion injury and clinical outcomes. Transplant Rev (Orlando). 2020 07; 34(3):100549. PMID: 32498978.
      Citations: 1     Fields:    Translation:Humans
    43. Pinto Marques H, Gomes da Silva S, De Martin E, Agopian VG, Martins PN. Emerging biomarkers in HCC patients: Current status. Int J Surg. 2020 Oct; 82S:70-76. PMID: 32344023.
      Citations: 13     Fields:    Translation:Humans
    44. Yao CG, Martins PN. Nanotechnology Applications in Transplantation Medicine. Transplantation. 2020 04; 104(4):682-693. PMID: 31651794.
      Citations: 8     Fields:    Translation:HumansAnimals
    45. Taner T, Martins PN, Ling Q, Ng KT, Huang KT, Eymard C, Bhat M, Bonaccorsi-Riani E, Mas VR, Selzner M, Ekser B. What Is Hot and New in Basic and Translational Science in Liver Transplantation in 2019? Report of the Basic and Translational Research Committee of the International Liver Transplantation Society. Transplantation. 2020 03; 104(3):516-521. PMID: 31815901.
      Citations: 1     Fields:    Translation:Humans
    46. Brüggenwirth IMA, van Leeuwen OB, de Vries Y, Bodewes SB, Adelmeijer J, Wiersema-Buist J, Lisman T, Martins PN, de Meijer VE, Porte RJ. Extended hypothermic oxygenated machine perfusion enables ex situ preservation of porcine livers for up to 24 hours. JHEP Rep. 2020 Apr; 2(2):100092. PMID: 32195456.
    47. Chen A, Ahmad M, Flescher A, Freeman WL, Little S, Martins PN, Veatch RM, Wightman A, Ladin K. Access to transplantation for persons with intellectual disability: Strategies for nondiscrimination. Am J Transplant. 2020 08; 20(8):2009-2016. PMID: 31873978.
      Citations: 2     Fields:    Translation:Humans
    48. Buchwald JE, Xu J, Bozorgzadeh A, Martins PN. Therapeutics administered during ex vivo liver machine perfusion: An overview. World J Transplant. 2020 Jan 18; 10(1):1-14. PMID: 32110510.
    49. Brüggenwirth IMA, Martins PN. RNA interference therapeutics in organ transplantation: The dawn of a new era. Am J Transplant. 2020 04; 20(4):931-941. PMID: 31680428.
      Citations: 8     Fields:    Translation:Humans
    50. Dolgin NH, Movahedi B, Anderson FA, Brüggenwirth IM, Martins PN, Bozorgzadeh A. Impact of recipient functional status on 1-year liver transplant outcomes. World J Transplant. 2019 Nov 20; 9(7):145-157. PMID: 31850158.
    51. Tran AP, Martins PN, Papazian ZG, Vanguri VK, Movahedi B, Fan PY, Bodziak KA, Yates JK, Sokoloff MH, Bozorgzadeh A. Transplantation of Renal Allograft After Removal of Renal Cell Carcinoma: Case Report and Review of the Literature. Exp Clin Transplant. 2021 07; 19(7):732-735. PMID: 31580237.
      Citations:    Fields:    Translation:Humans
    52. Martins PN, Selzner M, Dayangac M, Ling Q, Ng KT, Huang KT, Taner T, Mas VR, Ekser B. What Is Hot and New in Basic Science in Liver Transplantation in 2018? Report of the Basic Science Committee of the International Liver Transplantation Society. Transplantation. 2019 04; 103(4):654-659. PMID: 30801512.
      Citations:    Fields:    Translation:Humans
    53. Gillooly AR, Perry J, Martins PN. First Report of siRNA Uptake (for RNA Interference) During Ex Vivo Hypothermic and Normothermic Liver Machine Perfusion. Transplantation. 2019 03; 103(3):e56-e57. PMID: 30418428.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    54. Martins PN, Berendsen TA, Yeh H, Bruinsma BG, Izamis ML, Op den Dries S, Gillooly AR, Porte R, Yarmush ML, Uygun K, Markmann JF. Oxygenated UW Solution Decreases ATP Decay and Improves Survival After Transplantation of DCD Liver Grafts. Transplantation. 2019 02; 103(2):363-370. PMID: 30422952.
      Citations: 5     Fields:    Translation:Animals
    55. Dutkowski P, Guarrera JV, de Jonge J, Martins PN, Porte RJ, Clavien PA. Evolving Trends in Machine Perfusion for Liver Transplantation. Gastroenterology. 2019 05; 156(6):1542-1547. PMID: 30660724.
      Citations: 29     Fields:    Translation:Humans
    56. Thijssen MF, Brüggenwirth IMA, Gillooly A, Khvorova A, Kowalik TF, Martins PN. Gene Silencing With siRNA (RNA Interference): A New Therapeutic Option During Ex Vivo Machine Liver Perfusion Preservation Liver Transpl. 2019 01; 25(1):140-151. PMID: 30561891.
      Citations: 12     Fields:    Translation:Humans
    57. Bath NM, Wang X, Bledsoe JR, Thijssen M, Ahearn A, Movahedi B, Bozorgzadeh A, Martins PN. The Use of Smartphone for Liver Graft Biopsy Assessment at the Time of Procurement. Transplantation. 2018 11; 102(11):e459-e460. PMID: 30080817.
      Citations:    Fields:    Translation:Humans
    58. Brüggenwirth IMA, Moore C, Mahboub P, Thijssen MF, E X, Leuvenink HGD, Mandrekar P, Wang X, Kowalik TF, Porte RJ, Martins PN. A Comparative Study of Single and Dual Perfusion During End-ischemic Subnormothermic Liver Machine Preservation. Transplant Direct. 2018 Nov; 4(11):e400. PMID: 30534591.
    59. Costello R, Kissenpfennig A, Martins PN, McDaid J. Development of transplant immunosuppressive agents - considerations in the use of animal models. Expert Opin Drug Discov. 2018 11; 13(11):1041-1053. PMID: 30332905.
      Citations: 3     Fields:    Translation:HumansAnimals
    60. Dolgin NH, Smith AJ, Harrington SG, Movahedi B, Martins PNA, Bozorgzadeh A. Association Between Sarcopenia and Functional Status in Liver Transplant Patients. Exp Clin Transplant. 2019 10; 17(5):653-664. PMID: 30295589.
      Citations: 2     Fields:    Translation:Humans
    61. Martins PN. Transplantation of Livers From Viremic Hepatitis C Virus-Positive Donors Into Hepatitis C Virus-Negative Recipients. Hepatology. 2018 10; 68(4):1656. PMID: 29888797.
      Citations:    Fields:    Translation:HumansCells
    62. Martins PN, Gillooly AR, Movahedi B, Bozorgzadeh A. Bipolar Sealing Device Use in Pancreas Graft Preparation: A Novel Tieless Backtable Surgery Technique. Transplant Direct. 2018 Oct; 4(10):e397. PMID: 30498773.
    63. Hendrix RJ, Martins PN, Stoff JS, Ahearn A, Bozorgzadeh A, Movahedi B. Successful Renal Transplantation after Presumed Cyanide Toxicity Treated with Hydroxocobalamin and Review of the Literature. Case Rep Transplant. 2018; 2018:3753479. PMID: 30271651.
    64. Martins PN, Brüggenwirth IMA, McDaid J, Hertl M, Kawai T, Elias N, Chung RT, Markmann JF. Heat Stroke as a Cause of Liver Failure and Evaluation of Liver Transplant. Exp Clin Transplant. 2022 06; 20(6):621-626. PMID: 30119616.
      Citations: 3     Fields:    Translation:Humans
    65. Martins PN, Rawson A, Movahedi B, Brüggenwirth IMA, Dolgin NH, Martins AB, Mahboub P, Bozorgzadeh A. Single-Center Experience With Liver Transplant Using Donors With Very High Transaminase Levels. Exp Clin Transplant. 2019 08; 17(4):498-506. PMID: 30119618.
      Citations: 1     Fields:    Translation:HumansCells
    66. Quintini C, Martins PN, Shah S, Killackey M, Reed A, Guarrera J, Axelrod DA. Implementing an innovated preservation technology: The American Society of Transplant Surgeons' (ASTS) Standards Committee White Paper on Ex Situ Liver Machine Perfusion. Am J Transplant. 2018 08; 18(8):1865-1874. PMID: 29791060.
      Citations: 5     Fields:    Translation:Humans
    67. Cheng Q, Patel K, Lei B, Rucker L, Allen DP, Zhu P, Vasu C, Martins PN, Goddard M, Nadig SN, Atkinson C. Donor pretreatment with nebulized complement C3a receptor antagonist mitigates brain-death induced immunological injury post-lung transplant. Am J Transplant. 2018 10; 18(10):2417-2428. PMID: 29504277.
      Citations: 15     Fields:    Translation:HumansAnimals
    68. Martins PN, Mustian MN, MacLennan PA, Ortiz JA, Akoad M, Caicedo JC, Echeverri GJ, Gray SH, Lopez-Soler RI, Gunasekaran G, Kelly B, Mobley CM, Black SM, Esquivel C, Locke JE. Impact of the new kidney allocation system A2/A2B ? B policy on access to transplantation among minority candidates. Am J Transplant. 2018 08; 18(8):1947-1953. PMID: 29509285.
      Citations: 9     Fields:    Translation:Humans
    69. Uehara M, Solhjou Z, Banouni N, Kasinath V, Xiaqun Y, Dai L, Yilmam O, Yilmaz M, Ichimura T, Fiorina P, Martins PN, Ohori S, Guleria I, Maarouf OH, Tullius SG, McGrath MM, Abdi R. Ischemia augments alloimmune injury through IL-6-driven CD4+ alloreactivity. Sci Rep. 2018 02 06; 8(1):2461. PMID: 29410442.
      Citations: 17     Fields:    Translation:AnimalsCells
    70. Sheppard SE, Marecki HL, Psoinos CM, Movahedi B, Furman MJ, Bozorgzadeh A, Martins PN. Acute Appendicitis after Liver Transplantation: A Case Report and Review of the Literature. Int J Organ Transplant Med. 2017; 8(4):208-212. PMID: 29321837.
    71. Martins PN, Movahedi B, Bozorgzadeh A. Transplanting HCV-Infected Kidneys into Uninfected Recipients. N Engl J Med. 2017 09 14; 377(11):1104-5. PMID: 28902584.
      Citations: 2     Fields:    Translation:Humans
    72. Brüggenwirth IMA, Dolgin NH, Porte RJ, Bozorgzadeh A, Martins PNA. Donor Diabetes and Prolonged Cold Ischemia Time Synergistically Increase the Risk of Graft Failure After Liver Transplantation. Transplant Direct. 2017 Jul; 3(7):e173. PMID: 28706976.
    73. Martins PN, Kim I, Bozorgzadeh A. Allocation of organs to cognitively impaired patients. Pediatr Transplant. 2017 09; 21(6). PMID: 28574199.
      Citations:    Fields:    Translation:Humans
    74. Marecki H, Bozorgzadeh A, Porte RJ, Leuvenink HG, Uygun K, Martins PN. Liver ex situ machine perfusion preservation: A review of the methodology and results of large animal studies and clinical trials. Liver Transpl. 2017 05; 23(5):679-695. PMID: 28240817.
      Citations: 30     Fields:    Translation:HumansAnimals
    75. Costa BP, Martins P, Verissimo C, Simões M, Tomé M, Grazina M, Pimentel J, Castro-Sousa F. Intestinal dysfunction in the critical trauma patients - An early and frequent event. Nutr Hosp. 2017 Mar 30; 34(2):284-289. PMID: 28421780.
      Citations:    Fields:    Translation:Humans
    76. Dolgin NH, Martins PN, Movahedi B, Lapane KL, Anderson FA, Bozorgzadeh A. Functional status predicts postoperative mortality after liver transplantation. Clin Transplant. 2016 11; 30(11):1403-1410. PMID: 27439897.
      Citations: 23     Fields:    Translation:Humans
    77. Mahboub P, Bozorgzadeh A, Martins PN. Potential approaches to improve the outcomes of donation after cardiac death liver grafts. World J Transplant. 2016 Jun 24; 6(2):314-20. PMID: 27358776.
    78. Oltean M, Barrenäs C, Martins PN, Herlenius G, Gustafsson B, Friman S, Bennet W. Recipient Hyperbilirubinemia May Reduce Ischemia-Reperfusion Injury but Fails to Improve Outcome in Clinical Liver Transplantation. Gastroenterol Res Pract. 2016; 2016:6964856. PMID: 27313607.
    79. Dolgin NH, Movahedi B, Martins PN, Goldberg R, Lapane KL, Anderson FA, Bozorgzadeh A. Decade-Long Trends in Liver Transplant Waitlist Removal Due to Illness Severity: The Impact of Centers for Medicare and Medicaid Services Policy. J Am Coll Surg. 2016 06; 222(6):1054-65. PMID: 27178368.
      Citations: 3     Fields:    Translation:Humans
    80. Mahboub P, Ottens P, Seelen M, 't Hart N, Van Goor H, Ploeg R, Martins PN, Leuvenink H. Correction: Gradual Rewarming with Gradual Increase in Pressure during Machine Perfusion after Cold Static Preservation Reduces Kidney Ischemia Reperfusion Injury. PLoS One. 2016; 11(3):e0152006. PMID: 26977593.
      Citations: 2     Fields:    
    81. Bruinsma BG, Sridharan GV, Weeder PD, Avruch JH, Saeidi N, Özer S, Geerts S, Porte RJ, Heger M, van Gulik TM, Martins PN, Markmann JF, Yeh H, Uygun K. Metabolic profiling during ex vivo machine perfusion of the human liver. Sci Rep. 2016 Mar 03; 6:22415. PMID: 26935866.
      Citations: 43     Fields:    Translation:Humans
    82. Brüggenwirth IMA, Burlage LC, Porte RJ, Martins PN. Is single portal vein perfusion the best approach for machine preservation of liver grafts? J Hepatol. 2016 May; 64(5):1194-1195. PMID: 26836281.
      Citations: 5     Fields:    
    83. Mahboub P, Ottens P, Seelen M, 't Hart N, t Hart N, Van Goor H, Ploeg R, Martins PN, Martins P, Leuvenink H. Gradual Rewarming with Gradual Increase in Pressure during Machine Perfusion after Cold Static Preservation Reduces Kidney Ischemia Reperfusion Injury. PLoS One. 2015; 10(12):e0143859. PMID: 26630031.
      Citations: 14     Fields:    Translation:AnimalsCells
    84. Burlage LC, Karangwa SA, Lisman T, Martins PN, Porte RJ. Thrombolytic protocol minimizes ischemic-type biliary complications in liver transplantation from donation after circulatory death donors. Liver Transpl. 2015 Sep; 21(9):1231-2. PMID: 26045355.
      Citations: 2     Fields:    Translation:Humans
    85. Martins PN, Movahedi B, Bozorgzadeh A. Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases: A Paradigm Change? Ann Surg. 2015 Jul; 262(1):e12. PMID: 24424153.
      Citations: 4     Fields:    Translation:Humans
    86. Lei J, Kim JI, Shi S, Zhang X, Machaidze Z, Lee S, Schuetz C, Martins PN, Oura T, Farkash EA, Rosales IA, Smith RN, Stott R, Lee KM, Soohoo J, Boskovic S, Cappetta K, Nadazdin OM, Yamada Y, Yeh H, Kawai T, Sachs DH, Benichou G, Markmann JF. Pilot Study Evaluating Regulatory T Cell-Promoting Immunosuppression and Nonimmunogenic Donor Antigen Delivery in a Nonhuman Primate Islet Allotransplantation Model. Am J Transplant. 2015 Oct; 15(10):2739-49. PMID: 26014796.
      Citations: 17     Fields:    Translation:AnimalsCells
    87. McDaid J, Scott CJ, Kissenpfennig A, Chen H, Martins PN. The utility of animal models in developing immunosuppressive agents. Eur J Pharmacol. 2015 Jul 15; 759:295-302. PMID: 25814252.
      Citations: 3     Fields:    Translation:HumansAnimals
    88. Izamis ML, Efstathiades A, Keravnou C, Georgiadou S, Martins PN, Averkiou MA. Effects of air embolism size and location on porcine hepatic microcirculation in machine perfusion. Liver Transpl. 2014 May; 20(5):601-11. PMID: 24478135.
      Citations: 2     Fields:    Translation:Animals
    89. Bruinsma BG, Yeh H, Ozer S, Martins PN, Farmer A, Wu W, Saeidi N, Op den Dries S, Berendsen TA, Smith RN, Markmann JF, Porte RJ, Yarmush ML, Uygun K, Izamis ML. Subnormothermic machine perfusion for ex vivo preservation and recovery of the human liver for transplantation. Am J Transplant. 2014 Jun; 14(6):1400-9. PMID: 24758155.
      Citations: 69     Fields:    Translation:Humans
    90. op den Dries S, Westerkamp AC, Karimian N, Gouw AS, Bruinsma BG, Markmann JF, Lisman T, Yeh H, Uygun K, Martins PN, Porte RJ. Injury to peribiliary glands and vascular plexus before liver transplantation predicts formation of non-anastomotic biliary strictures. J Hepatol. 2014 Jun; 60(6):1172-9. PMID: 24560661.
      Citations: 45     Fields:    Translation:Humans
    91. Martins PN. Normothermic machine preservation as an approach to decrease biliary complications of DCD liver grafts. Am J Transplant. 2013 Dec; 13(12):3287-8. PMID: 24148669.
      Citations: 2     Fields:    Translation:Animals
    92. Martins PN, Tullius SG, Markmann JF. Immunosenescence and immune response in organ transplantation. Int Rev Immunol. 2014 May-Jun; 33(3):162-73. PMID: 24127845.
      Citations: 16     Fields:    Translation:Humans
    93. Martins PN, McDaid J, Markmann JF. Left accessory hepatic artery damage by a misplaced gastric band in a deceased liver donor. Transplantation. 2013 Sep; 96(6):e45-6. PMID: 24042978.
      Citations:    Fields:    Translation:Humans
    94. McDaid J, Farkash EA, Steele DJ, Martins PN, Kotton CN, Elias N, Ko DS, Colvin RB, Hertl M. Transitional cell carcinoma arising within a pediatric donor renal transplant in association with BK nephropathy. Transplantation. 2013 Mar 15; 95(5):e28-30. PMID: 23503509.
      Citations: 5     Fields:    Translation:HumansCells
    95. Martins PN, Sheiner P, Facciuto M. Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis. Hepatobiliary Pancreat Dis Int. 2012 Oct; 11(5):549-52. PMID: 23060404.
      Citations: 9     Fields:    Translation:Humans
    96. Martins PN, Markmann JF. Age-related differences in hepatic ischemia/reperfusion: gene activation, liver injury, and protective effect of melatonin. J Surg Res. 2013 Nov; 185(1):e19-21. PMID: 22964269.
      Citations: 2     Fields:    Translation:Animals
    97. Martins PN, Varma MC, Elias N, Markmann JF. Image of the month. Portal vein gas associated with pneumatosis intestinalis. Arch Surg. 2012 Mar; 147(3):291-2. PMID: 22430916.
      Citations:    Fields:    Translation:Humans
    98. Venancio SI, do Nascimento PR, Rosa TE, Salum e Morais Mde L, Martins PN, Voloschko A. [Management practices of regional referencing: a comparative study of five cases in the State of São Paulo, Brazil]. Cien Saude Colet. 2011 Sep; 16(9):3951-64. PMID: 21987339.
      Citations: 1     Fields:    Translation:Humans
    99. Martins PN, Reddy S, Martins AB, Facciuto M. Follicular dendritic cell sarcoma of the liver: unusual presentation of a rare tumor and literature review. Hepatobiliary Pancreat Dis Int. 2011 Aug; 10(4):443-5. PMID: 21813397.
      Citations: 13     Fields:    Translation:Humans
    100. Martins PN. Clinical translation of remote ischemic preconditioning of the liver. Ann Surg. 2011 Jul; 254(1):180. PMID: 21606830.
      Citations: 1     Fields:    Translation:HumansAnimals
    101. Martins PN, Chang S, Mahadevapa B, Martins AB, Sheiner P. Liver grafts from selected older donors do not have significantly more ischaemia reperfusion injury. HPB (Oxford). 2011 Mar; 13(3):212-20. PMID: 21309940.
      Citations: 6     Fields:    Translation:Humans
    102. Varma MC, Kushner YB, Ko DS, Kawai T, Martins PN, Martins P, Kaur P, Markmann JF, Kotton CN. Early onset adenovirus infection after simultaneous kidney-pancreas transplant. Am J Transplant. 2011 Mar; 11(3):623-7. PMID: 21342452.
      Citations: 6     Fields:    Translation:HumansCells
    103. Martins PN. Effects of organ donor age on alloresponse. Am J Kidney Dis. 2011 Feb; 57(2):353-4. PMID: 21251547.
      Citations:    Fields:    Translation:HumansCells
    104. Martins PN. Liver graft vascular variant with 3 extra-hepatic arteries. Hepatobiliary Pancreat Dis Int. 2010 Jun; 9(3):319-20. PMID: 20525561.
      Citations:    Fields:    Translation:Humans
    105. Martins PN, Butt K, El-Sabrout R. Richter's hernia at a Tenckhoff catheter exit site. Surg Laparosc Endosc Percutan Tech. 2010 Jun; 20(3):e136-8. PMID: 20551795.
      Citations:    Fields:    Translation:Humans
    106. Martins PN, Kim-Schluger L, Rodriguez-Davalos M, Martins AB, Krachkova N, Facciuto M, Sheiner P. Massive pulmonary and intracardiac embolism during liver transplantation. Exp Clin Transplant. 2010 Jun; 8(2):184-8. PMID: 20565378.
      Citations: 1     Fields:    Translation:Humans
    107. Martins PN. Impact of donor and recipient age on allograft tolerance. Exp Clin Transplant. 2009 Jun; 7(2):67-77. PMID: 19715510.
      Citations: 4     Fields:    Translation:HumansAnimals
    108. Reutzel-Selke A, Pratschke J, Martins PN, Denecke C, Jurisch A, Kotsch K, Pascher A, Neuhaus P, Tullius SG. Ischemic preconditioning produces systemic protective and adoptively transferable effects. Kidney Int. 2008 Sep; 74(5):622-30. PMID: 18509319.
      Citations: 4     Fields:    Translation:AnimalsCells
    109. Martins PN. Assessment of graft function in rodent models of heart transplantation. Microsurgery. 2008; 28(7):565-70. PMID: 18767132.
      Citations: 8     Fields:    Translation:Animals
    110. Martins PN, Neuhaus P. Hepatic lobectomy and segmentectomy models using microsurgical techniques. Microsurgery. 2008; 28(3):187-91. PMID: 18286652.
      Citations: 3     Fields:    Translation:Animals
    111. Kotsch K, Martins PN, Klemz R, Janssen U, Gerstmayer B, Dernier A, Reutzel-Selke A, Kuckelkorn U, Tullius SG, Volk HD. Heme oxygenase-1 ameliorates ischemia/reperfusion injury by targeting dendritic cell maturation and migration. Antioxid Redox Signal. 2007 Dec; 9(12):2049-63. PMID: 17854277.
      Citations: 23     Fields:    Translation:AnimalsCells
    112. Martins PN, Theruvath TP, Neuhaus P. Rodent models of partial hepatectomies. Liver Int. 2008 Jan; 28(1):3-11. PMID: 18028319.
      Citations: 58     Fields:    Translation:Animals
    113. Martins PN, Glanemann M, Koelble K, Weidemann H, Neuhaus P. Ileus due to severe aggravation of retroperitoneal fibrosis after sigmoidectomy. Int J Colorectal Dis. 2008 Feb; 23(2):217-8. PMID: 17440738.
      Citations:    Fields:    Translation:Humans
    114. Martins PN, Neuhaus P. Surgical anatomy of the liver, hepatic vasculature and bile ducts in the rat. Liver Int. 2007 Apr; 27(3):384-92. PMID: 17355461.
      Citations: 22     Fields:    Translation:Animals
    115. Martins PN, Benckert C, Vetzke-Schlieker W, Pratschke J, Tullius SG, Neuhaus P. Intraduodenal diverticulum associated with a double common bile duct causing recurrent pancreatitis and cholangitis: report of a case. Surg Today. 2007; 37(4):320-4. PMID: 17387566.
      Citations:    Fields:    Translation:Humans
    116. Reutzel-Selke A, Jurisch A, Denecke C, Pascher A, Martins PN, Kessler H, Tamura A, Utku N, Pratschke J, Neuhaus P, Tullius SG. Donor age intensifies the early immune response after transplantation. Kidney Int. 2007 Apr; 71(7):629-36. PMID: 17264877.
      Citations: 18     Fields:    Translation:Animals
    117. Martins PN, Montero EF. Basic microsurgery training: comments and proposal. Acta Cir Bras. 2007 Jan-Feb; 22(1):79-81. PMID: 17293955.
      Citations: 3     Fields:    Translation:Humans
    118. Martins PN, Theruvath TP. Detachable cuffs for sutureless microvascular anastomosis. Microsurgery. 2007; 27(8):678-9. PMID: 17941107.
      Citations: 1     Fields:    Translation:Animals
    119. Martins PN. Technique of kidney transplantation in mice with anti-reflux urinary reconstruction. Int Braz J Urol. 2006 Nov-Dec; 32(6):713-8; discussion 719-20. PMID: 17201950.
      Citations: 4     Fields:    Translation:Animals
    120. Martins PN, Reutzel-Selke A, Jurisch A, Denecke C, Attrot K, Pascher A, Kotsch K, Pratschke J, Neuhaus P, Volk HD, Tullius SG. Induction of carbon monoxide in donor animals prior to organ procurement reduces graft immunogenicity and inhibits chronic allograft dysfunction. Transplantation. 2006 Oct 15; 82(7):938-44. PMID: 17038910.
      Citations: 12     Fields:    Translation:AnimalsCells
    121. Martins PN, Montero EF. Organization of a microsurgery laboratory. Acta Cir Bras. 2006 May-Jun; 21(3):187-9. PMID: 16751934.
      Citations: 2     Fields:    
    122. Martins PN, Chandraker A, Tullius SG. Modifying graft immunogenicity and immune response prior to transplantation: potential clinical applications of donor and graft treatment. Transpl Int. 2006 May; 19(5):351-9. PMID: 16623870.
      Citations: 13     Fields:    Translation:Humans
    123. Martins PN. Learning curve, surgical results and operative complications for kidney transplantation in mice. Microsurgery. 2006; 26(8):590-3. PMID: 17066406.
      Citations: 5     Fields:    Translation:Animals
    124. Martins PN. Kidney transplantation in the rat: a modified technique using hydrodissection. Microsurgery. 2006; 26(7):543-6. PMID: 17001636.
      Citations: 4     Fields:    Translation:Animals
    125. Martins PN, Pratschke J, Pascher A, Fritsche L, Frei U, Neuhaus P, Tullius SG. Age and immune response in organ transplantation. Transplantation. 2005 Jan 27; 79(2):127-32. PMID: 15665758.
      Citations: 28     Fields:    Translation:Humans
    126. Martins PN, Kessler H, Jurisch A, Reutzel-Selke A, Kramer J, Pascher A, Pratschke J, Neuhaus P, Volk HD, Tullius SG. Induction of heme oxygenase-1 in the donor reduces graft immunogenicity. Transplant Proc. 2005 Jan-Feb; 37(1):384-6. PMID: 15808653.
      Citations: 9     Fields:    Translation:Animals
    127. Reutzel-Selke A, Filatenkov A, Jurisch A, Denecke C, Martins PN, Pascher A, Jonas S, Pratschke J, Neuhaus P, Tullius SG. Grafts from elderly donors elicit a stronger immune response in the early period posttransplantation: a study in a rat model. Transplant Proc. 2005 Jan-Feb; 37(1):382-3. PMID: 15808652.
      Citations: 5     Fields:    Translation:AnimalsCells
    128. Martins PN, Mashreghi MF, Reutzel-Selke A, Neuhaus P, Volk HD, Tullius SG, Kotsch K. Quantification of donor-derived DNA in serum: a new approach of acute rejection diagnosis in a rat kidney transplantation model. Transplant Proc. 2005 Jan-Feb; 37(1):87-8. PMID: 15808556.
      Citations:    Fields:    Translation:Animals
    129. Martins PN, Reuzel-Selke A, Jurisch A, Atrott K, Pascher A, Pratschke J, Buelow R, Neuhaus P, Volk HD, Tullius SG. Induction of carbon monoxide in the donor reduces graft immunogenicity and chronic graft deterioration. Transplant Proc. 2005 Jan-Feb; 37(1):379-81. PMID: 15808651.
      Citations: 11     Fields:    Translation:Animals
    130. Tullius SG, Nieminen-Kelhä M, Buelow R, Reutzel-Selke A, Martins PN, Pratschke J, Bachmann U, Lehmann M, Southard D, Iyer S, Schmidbauer G, Sawitzki B, Reinke P, Neuhaus P, Volk HD. Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1. Transplantation. 2002 Sep 15; 74(5):591-8. PMID: 12352873.
      Citations: 28     Fields:    Translation:AnimalsCells
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