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Gary R Ostroff PhD

TitleProfessor
InstitutionUMass Chan Medical School
DepartmentProgram in Molecular Medicine
AddressUMass Chan Medical School
373 Plantation Street Two Biotech Suite 113
Worcester MA 01605
Phone508-856-1930
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentNeuroNexus Institute

    InstitutionT.H. Chan School of Medicine
    DepartmentPediatrics

    InstitutionT.H. Chan School of Medicine
    DepartmentProgram in Molecular Medicine

    InstitutionT.H. Chan School of Medicine
    DepartmentRNA Therapeutics Institute

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMasters in Clinical Investigation

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentTranslational Science


    Collapse Biography 
    Collapse education and training
    Delaware Valley College of Science and Agriculture, Doylestown, PA, United StatesBSBiology
    University of Delaware, Newark, DE, United StatesPHDMolecular Medicine

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hoang D, Flanagan K, Ding Q, Cazeault NR, Li H, D?az-Valerio S, Rus F, Darfour EA, Kass E, Petersson KH, Nielsen MK, Liesegang H, Ostroff GR, Aroian RV. Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites. PLoS Negl Trop Dis. 2024 Oct; 18(10):e0012611. PMID: 39453964.
      Citations:    
    2. Soto ER, Rus F, Ostroff GR. Yeast Particle Encapsulation of Azole Fungicides for Enhanced Treatment of Azole-Resistant Candida albicans. J Funct Biomater. 2024 Jul 23; 15(8). PMID: 39194641.
      Citations:    
    3. Whelan AO, Flick-Smith HC, Walker NJ, Abraham A, Levitz SM, Ostroff GR, Oyston PCF. A glucan-particle based tularemia subunit vaccine induces T-cell immunity and affords partial protection in an inhalation rat infection model. PLoS One. 2024; 19(5):e0294998. PMID: 38713688.
      Citations:    
    4. Campuzano A, Pentakota KD, Liao YR, Zhang H, Wiederhold NP, Ostroff GR, Hung CY. A Recombinant Multivalent Vaccine (rCpa1) Induces Protection for C57BL/6 and HLA Transgenic Mice against Pulmonary Infection with Both Species of Coccidioides. Vaccines (Basel). 2024 Jan 09; 12(1). PMID: 38250880.
      Citations:    
    5. Soto ER, Specht CA, Lee CK, Levitz SM, Ostroff GR. One Step Purification-Vaccine Delivery System. Pharmaceutics. 2023 May 01; 15(5). PMID: 37242632.
      Citations:    
    6. Soto ER, Specht CA, Rus F, Lee CK, Abraham A, Levitz SM, Ostroff GR. An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability. J Control Release. 2023 05; 357:175-184. PMID: 36933700.
      Citations: 1     Fields:    Translation:Animals
    7. Soto ER, Rus F, Mirza Z, Ostroff GR. Yeast Particles for Encapsulation of Terpenes and Essential Oils. Molecules. 2023 Feb 28; 28(5). PMID: 36903519.
      Citations:    Fields:    Translation:Animals
    8. Wang R, Oliveira LVN, Lourenco D, Gomez CL, Lee CK, Hester MM, Mou Z, Ostroff GR, Specht CA, Levitz SM. Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases. NPJ Vaccines. 2023 Feb 02; 8(1):6. PMID: 36732332.
      Citations:    
    9. Hester MM, Oliveira LVN, Wang R, Mou Z, Lourenco D, Ostroff GR, Specht CA, Levitz SM. Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis. Front Immunol. 2022; 13:1015586. PMID: 36248898.
      Citations:    Fields:    Translation:Animals
    10. Chicca J, Cazeault NR, Rus F, Abraham A, Garceau C, Li H, Atwa SM, Flanagan K, Soto ER, Morrison MS, Gazzola D, Hu Y, Liu DR, Nielsen MK, Urban JF, Ostroff GR, Aroian RV. Efficient and Scalable Process to Produce Novel and Highly Bioactive Purified Cytosolic Crystals from Bacillus thuringiensis. Microbiol Spectr. 2022 08 31; 10(4):e0235622. PMID: 35946940.
      Citations:    Fields:    Translation:HumansAnimalsCells
    11. Soto ER, Rus F, Ostroff GR. Yeast Particles Hyper-Loaded with Terpenes for Biocide Applications. Molecules. 2022 Jun 02; 27(11). PMID: 35684516.
      Citations: 1     Fields:    Translation:Animals
    12. Hamza ZK, Hathout AS, Ostroff G, Soto E, Sabry BA, El-Hashash MA, Hassan NS, Aly SE. Assessment of the protective effect of yeast cell wall ?-glucan encapsulating humic acid nanoparticles as an aflatoxin B1 adsorbent in vivo. J Biochem Mol Toxicol. 2022 Jan; 36(1):e22941. PMID: 34726330.
      Citations: 1     Fields:    Translation:Animals
    13. Soto ER, Rus F, Li H, Garceau C, Chicca J, Elfawal M, Gazzola D, Nielsen MK, Urban JF, Aroian RV, Ostroff GR. Yeast Particle Encapsulation of Scaffolded Terpene Compounds for Controlled Terpene Release. Foods. 2021 May 27; 10(6). PMID: 34071798.
      Citations:    
    14. Chase Huizar C, Ji N, Reddick R, Ostroff GR, Forsthuber TG. Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis. Cell Immunol. 2021 08; 366:104383. PMID: 34111646.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    15. Urban JF, Nielsen MK, Gazzola D, Xie Y, Beshah E, Hu Y, Li H, Rus F, Flanagan K, Draper A, Vakalapudi S, Li RW, Ostroff GR, Aroian RV. An inactivated bacterium (paraprobiotic) expressing Bacillus thuringiensis Cry5B as a therapeutic for Ascaris and Parascaris spp. infections in large animals. One Health. 2021 Jun; 12:100241. PMID: 33889707.
      Citations:    
    16. Specht CA, Homan EJ, Lee CK, Mou Z, Gomez CL, Hester MM, Abraham A, Rus F, Ostroff GR, Levitz SM. Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles. mBio. 2021 02 22; 13(1):e0336721. PMID: 35089095.
      Citations: 10     Fields:    Translation:HumansAnimals
    17. Li H, Abraham A, Gazzola D, Hu Y, Beamer G, Flanagan K, Soto E, Rus F, Mirza Z, Draper A, Vakalapudi S, Stockman C, Bain P, Urban JF, Ostroff GR, Aroian RV. Recombinant Paraprobiotics as a New Paradigm for Treating Gastrointestinal Nematode Parasites of Humans. Antimicrob Agents Chemother. 2021 02 17; 65(3). PMID: 33318013.
      Citations: 3     Fields:    Translation:HumansAnimals
    18. Sanders J, Xie Y, Gazzola D, Li H, Abraham A, Flanagan K, Rus F, Miller M, Hu Y, Guynn S, Draper A, Vakalapudi S, Petersson KH, Zarlenga D, Li RW, Urban JF, Ostroff GR, Zajac A, Aroian RV. A new paraprobiotic-based treatment for control of Haemonchus contortus in sheep. Int J Parasitol Drugs Drug Resist. 2020 12; 14:230-236. PMID: 33242790.
      Citations: 8     Fields:    Translation:Animals
    19. O'Regan GC, Farag SH, Ostroff GR, Tabrizi SJ, Andre R. Wild-type huntingtin regulates human macrophage function. Sci Rep. 2020 10 14; 10(1):17269. PMID: 33057179.
      Citations: 6     Fields:    Translation:HumansCells
    20. Mirza Z, Soto ER, Hu Y, Nguyen TT, Koch D, Aroian RV, Ostroff GR. Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes. Molecules. 2020 Jun 27; 25(13). PMID: 32605043.
      Citations: 10     Fields:    Translation:HumansAnimals
    21. Campuzano A, Zhang H, Ostroff GR, Dos Santos Dias L, W?thrich M, Klein BS, Yu JJ, Lara HH, Lopez-Ribot JL, Hung CY. CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection. J Immunol. 2020 06 15; 204(12):3296-3306. PMID: 32358020.
      Citations: 15     Fields:    Translation:AnimalsCells
    22. Hayden CA, Landrock D, Hung CY, Ostroff G, Fake GM, Walker JH, Kier A, Howard JA. Co-Administration of Injected and Oral Vaccine Candidates Elicits Improved Immune Responses over Either Route Alone. Vaccines (Basel). 2020 Jan 21; 8(1). PMID: 31973150.
      Citations:    
    23. Dobson HE, Dias LDS, Kohn EM, Fites S, Wiesner DL, Dileepan T, Kujoth GC, Abraham A, Ostroff GR, Klein BS, W?thrich M. Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance. Mucosal Immunol. 2020 05; 13(3):518-529. PMID: 31900406.
      Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    24. Hester MM, Lee CK, Abraham A, Khoshkenar P, Ostroff GR, Levitz SM, Specht CA. Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens. Vaccine. 2020 01 16; 38(3):620-626. PMID: 31699504.
      Citations: 18     Fields:    Translation:Animals
    25. Charuchaibovorn S, Sanprasert V, Sutthanont N, Hu Y, Abraham A, Ostroff GR, Aroian RV, Jaleta TG, Lok JB, Nuchprayoon S. Bacillus thuringiensis Cry5B is Active against Strongyloides stercoralis in vitro. Am J Trop Med Hyg. 2019 11; 101(5):1177-1182. PMID: 31516117.
      Citations: 1     Fields:    Translation:AnimalsCells
    26. Abraham A, Ostroff G, Levitz SM, Oyston PCF. A novel vaccine platform using glucan particles for induction of protective responses against Francisella tularensis and other pathogens. Clin Exp Immunol. 2019 11; 198(2):143-152. PMID: 31400225.
      Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    27. Soto ER, Kim HC, Yagita H, De Jesus M, Ostroff GR. Polydopamine Coating of Glucan Particles Increases Uptake into Peyer's Patches. ACS Appl Bio Mater. 2019 Sep 16; 2(9):3748-3754. PMID: 35021348.
      Citations:    Fields:    
    28. Hayden CA, Hung CY, Zhang H, Negron A, Esquerra R, Ostroff G, Abraham A, Lopez AG, Gonzales JE, Howard JA. Maize-Produced Ag2 as a Subunit Vaccine for Valley Fever. J Infect Dis. 2019 07 19; 220(4):615-623. PMID: 31184702.
      Citations: 5     Fields:    Translation:AnimalsCellsPHPublic Health
    29. Noon JB, Schwarz EM, Ostroff GR, Aroian RV. A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection. PLoS Negl Trop Dis. 2019 04; 13(4):e0007345. PMID: 31009474.
      Citations: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    30. Hung CY, Zhang H, Castro-Lopez N, Ostroff GR, Khoshlenar P, Abraham A, Cole GT, Negron A, Forsthuber T, Peng T, Galgiani JN, Ampel NM, Yu JJ. Glucan-Chitin Particles Enhance Th17 Response and Improve Protective Efficacy of a Multivalent Antigen (rCpa1) against Pulmonary Coccidioides posadasii Infection. Infect Immun. 2018 11; 86(11). PMID: 30104216.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    31. Whelan AO, Flick-Smith HC, Homan J, Shen ZT, Carpenter Z, Khoshkenar P, Abraham A, Walker NJ, Levitz SM, Ostroff GR, Oyston PCF. Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles. PLoS One. 2018; 13(10):e0200213. PMID: 30296254.
      Citations: 10     Fields:    Translation:AnimalsCells
    32. Alexander MP, Fiering SN, Ostroff GR, Cramer RA, Mullins DW. Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung. Cancer Immunol Immunother. 2018 Nov; 67(11):1731-1742. PMID: 30167860.
      Citations: 6     Fields:    Translation:AnimalsCells
    33. Hamza Z, El-Hashash M, Aly S, Hathout A, Soto E, Sabry B, Ostroff G. Preparation and characterization of yeast cell wall beta-glucan encapsulated humic acid nanoparticles as an enhanced aflatoxin B1 binder. Carbohydr Polym. 2019 Jan 01; 203:185-192. PMID: 30318202.
      Citations: 10     Fields:    Translation:AnimalsCells
    34. Singh N, Gallagher HC, Song R, Dhinsa JK, Ostroff GR, De Jesus M. RNA isolation from Peyer's patch lymphocytes and mononuclear phagocytes to determine gene expression profiles using NanoString technology. J Biol Methods. 2018; 5(3):e95. PMID: 31453245.
      Citations:    
    35. Li Q, Nirala NK, Nie Y, Chen HJ, Ostroff G, Mao J, Wang Q, Xu L, Ip YT. Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth. Dev Cell. 2018 05 21; 45(4):433-449.e6. PMID: 29754801.
      Citations: 33     Fields:    Translation:AnimalsCells
    36. Hu Y, Nguyen TT, Lee ACY, Urban JF, Miller MM, Zhan B, Koch DJ, Noon JB, Abraham A, Fujiwara RT, Bowman DD, Ostroff GR, Aroian RV. Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure. Int J Parasitol Drugs Drug Resist. 2018 08; 8(2):287-294. PMID: 29772478.
      Citations: 11     Fields:    Translation:AnimalsCells
    37. Deepe GS, Buesing WR, Ostroff GR, Abraham A, Specht CA, Huang H, Levitz SM. Vaccination with an alkaline extract of Histoplasma capsulatum packaged in glucan particles confers protective immunity in mice. Vaccine. 2018 05 31; 36(23):3359-3367. PMID: 29729993.
      Citations: 18     Fields:    Translation:AnimalsCells
    38. Rockenstein E, Ostroff G, Dikengil F, Rus F, Mante M, Florio J, Adame A, Trinh I, Kim C, Overk C, Masliah E, Rissman RA. Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies. J Neurosci. 2018 01 24; 38(4):1000-1014. PMID: 29246926.
      Citations: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    39. Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM. Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. mBio. 2017 11 28; 8(6). PMID: 29184017.
      Citations: 39     Fields:    Translation:AnimalsCells
    40. Miller JRC, Pfister EL, Liu W, Andre R, Tr?ger U, Kennington LA, Lo K, Dijkstra S, Macdonald D, Ostroff G, Aronin N, Tabrizi SJ. Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells. Sci Rep. 2017 04 24; 7:46740. PMID: 28436437.
      Citations: 12     Fields:    Translation:HumansCells
    41. Mirza Z, Soto ER, Dikengil F, Levitz SM, Ostroff GR. Beta-Glucan Particles as Vaccine Adjuvant Carriers. Methods Mol Biol. 2017; 1625:143-157. PMID: 28584989.
      Citations: 22     Fields:    Translation:Animals
    42. Soto ER, O'Connell O, Dikengil F, Peters PJ, Clapham PR, Ostroff GR. Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages. J Drug Deliv. 2016; 2016:8520629. PMID: 27965897.
      Citations:    
    43. Specht CA, Lee CK, Huang H, Tipper DJ, Shen ZT, Lodge JK, Leszyk J, Ostroff GR, Levitz SM. Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts. mBio. 2015 Dec 22; 6(6):e01905-15. PMID: 26695631.
      Citations: 42     Fields:    Translation:AnimalsCellsPHPublic Health
    44. De Jesus M, Rodriguez AE, Yagita H, Ostroff GR, Mantis NJ. Sampling of Candida albicans and Candida tropicalis by Langerin-positive dendritic cells in mouse Peyer's patches. Immunol Lett. 2015 Nov; 168(1):64-72. PMID: 26386376.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    45. W?thrich M, Brandhorst TT, Sullivan TD, Filutowicz H, Sterkel A, Stewart D, Li M, Lerksuthirat T, LeBert V, Shen ZT, Ostroff G, Deepe GS, Hung CY, Cole G, Walter JA, Jenkins MK, Klein B. Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes. Cell Host Microbe. 2015 Apr 08; 17(4):452-65. PMID: 25800545.
      Citations: 38     Fields:    Translation:AnimalsCells
    46. Levitz SM, Huang H, Ostroff GR, Specht CA. Exploiting fungal cell wall components in vaccines. Semin Immunopathol. 2015 Mar; 37(2):199-207. PMID: 25404118.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    47. Bueter CL, Lee CK, Wang JP, Ostroff GR, Specht CA, Levitz SM. Spectrum and mechanisms of inflammasome activation by chitosan. J Immunol. 2014 Jun 15; 192(12):5943-51. PMID: 24829412.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    48. De Jesus M, Ostroff GR, Levitz SM, Bartling TR, Mantis NJ. A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling ?-glucan microparticles. PLoS One. 2014; 9(3):e91002. PMID: 24632738.
      Citations: 14     Fields:    Translation:AnimalsCells
    49. Tr?ger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Bj?rkqvist M, Ostroff GR, Aronin N, Tabrizi SJ. HTT-lowering reverses Huntington's disease immune dysfunction caused by NF?B pathway dysregulation. Brain. 2014 Mar; 137(Pt 3):819-33. PMID: 24459107.
      Citations: 84     Fields:    Translation:HumansCells
    50. Cole GT, Hung CY, Sanderson SD, Hurtgen BJ, W?thrich M, Klein BS, Deepe GS, Ostroff GR, Levitz SM. Novel strategies to enhance vaccine immunity against coccidioidomycosis. PLoS Pathog. 2013; 9(12):e1003768. PMID: 24367252.
      Citations: 20     Fields:    Translation:HumansAnimalsPHPublic Health
    51. De Smet R, Demoor T, Verschuere S, Dullaers M, Ostroff GR, Leclercq G, Allais L, Pilette C, Dierendonck M, De Geest BG, Cuvelier CA. ?-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination. J Control Release. 2013 Dec 28; 172(3):671-8. PMID: 24041710.
      Citations: 39     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    52. Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM. Characterization and optimization of the glucan particle-based vaccine platform. Clin Vaccine Immunol. 2013 Oct; 20(10):1585-91. PMID: 23945157.
      Citations: 38     Fields:    Translation:AnimalsCellsPHPublic Health
    53. Hurtgen BJ, Hung CY, Ostroff GR, Levitz SM, Cole GT. Construction and evaluation of a novel recombinant T cell epitope-based vaccine against Coccidioidomycosis. Infect Immun. 2012 Nov; 80(11):3960-74. PMID: 22949556.
      Citations: 41     Fields:    Translation:HumansAnimals
    54. Huang H, Ostroff GR, Lee CK, Agarwal S, Ram S, Rice PA, Specht CA, Levitz SM. Relative contributions of dectin-1 and complement to immune responses to particulate ?-glucans. J Immunol. 2012 Jul 01; 189(1):312-7. PMID: 22649195.
      Citations: 48     Fields:    Translation:AnimalsCells
    55. Soto ER, Caras AC, Kut LC, Castle MK, Ostroff GR. Glucan particles for macrophage targeted delivery of nanoparticles. J Drug Deliv. 2012; 2012:143524. PMID: 22013535.
      Citations:    
    56. Agarwal S, Specht CA, Haibin H, Ostroff GR, Ram S, Rice PA, Levitz SM. Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans. mBio. 2011; 2(5). PMID: 21878570.
      Citations: 24     Fields:    Translation:HumansAnimals
    57. Tesz GJ, Aouadi M, Prot M, Nicoloro SM, Boutet E, Amano SU, Goller A, Wang M, Guo CA, Salomon WE, Virbasius JV, Baum RA, O'Connor MJ, Soto E, Ostroff GR, Czech MP. Glucan particles for selective delivery of siRNA to phagocytic cells in mice. Biochem J. 2011 Jun 01; 436(2):351-62. PMID: 21418037.
      Citations: 40     Fields:    Translation:AnimalsCells
    58. Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM. Robust stimulation of humoral and cellular immune responses following vaccination with antigen-loaded beta-glucan particles. mBio. 2010 Jul 20; 1(3). PMID: 20802824.
      Citations: 60     Fields:    Translation:AnimalsCellsPHPublic Health
    59. Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature. 2009 Apr 30; 458(7242):1180-4. PMID: 19407801.
      Citations: 230     Fields:    Translation:AnimalsCells
    60. Huang H, Ostroff GR, Lee CK, Wang JP, Specht CA, Levitz SM. Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists. Infect Immun. 2009 May; 77(5):1774-81. PMID: 19273561.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    61. Soto ER, Ostroff GR. Characterization of multilayered nanoparticles encapsulated in yeast cell wall particles for DNA delivery. Bioconjug Chem. 2008 Apr; 19(4):840-8. PMID: 18376856.
      Citations: 50     Fields:    Translation:AnimalsCells
    62. Young SH, Ostroff GR, Zeidler-Erdely PC, Roberts JR, Antonini JM, Castranova V. A comparison of the pulmonary inflammatory potential of different components of yeast cell wall. J Toxicol Environ Health A. 2007 Jul; 70(13):1116-24. PMID: 17558806.
      Citations: 22     Fields:    Translation:AnimalsCells
    63. Hong F, Yan J, Baran JT, Allendorf DJ, Hansen RD, Ostroff GR, Xing PX, Cheung NK, Ross GD. Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J Immunol. 2004 Jul 15; 173(2):797-806. PMID: 15240666.
      Citations: 132     Fields:    Translation:AnimalsCells
    64. Hong F, Hansen RD, Yan J, Allendorf DJ, Baran JT, Ostroff GR, Ross GD. Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells. Cancer Res. 2003 Dec 15; 63(24):9023-31. PMID: 14695221.
      Citations: 51     Fields:    Translation:AnimalsCells
    65. Donzelli BG, Ostroff G, Harman GE. Enhanced enzymatic hydrolysis of langostino shell chitin with mixtures of enzymes from bacterial and fungal sources. Carbohydr Res. 2003 Sep 01; 338(18):1823-33. PMID: 12932365.
      Citations: 4     Fields:    Translation:AnimalsCells
    66. Kournikakis B, Mandeville R, Brousseau P, Ostroff G. Anthrax-protective effects of yeast beta 1,3 glucans. MedGenMed. 2003 Mar 21; 5(1):1. PMID: 12827062.
      Citations: 14     Fields:    Translation:AnimalsCells
    67. Niederman R, Kelderman H, Socransky S, Ostroff G, Genco C, Kent R, Stashenko P. Enhanced neutrophil emigration and Porphyromonas gingivalis reduction following PGG-glucan treatment of mice. Arch Oral Biol. 2002 Aug; 47(8):613-8. PMID: 12221019.
      Citations: 4     Fields:    Translation:AnimalsCells
    68. Bell S, Goldman VM, Bistrian BR, Arnold AH, Ostroff G, Forse RA. Effect of beta-glucan from oats and yeast on serum lipids. Crit Rev Food Sci Nutr. 1999 Mar; 39(2):189-202. PMID: 10198754.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    69. Stashenko P, Wang CY, Riley E, Wu Y, Ostroff G, Niederman R. Reduction of infection-stimulated periapical bone resorption by the biological response modifier PGG glucan. J Dent Res. 1995 Jan; 74(1):323-30. PMID: 7876425.
      Citations: 12     Fields:    Translation:AnimalsCells
    70. Onderdonk AB, Cisneros RL, Hinkson P, Ostroff G. Anti-infective effect of poly-beta 1-6-glucotriosyl-beta 1-3-glucopyranose glucan in vivo. Infect Immun. 1992 Apr; 60(4):1642-7. PMID: 1548086.
      Citations: 19     Fields:    Translation:AnimalsCells
    71. Simon ES, Toone EJ, Ostroff G, Bednarski MD, Whitesides GM. Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. Methods Enzymol. 1989; 179:275-87. PMID: 2560122.
      Citations: 2     Fields:    Translation:Cells
    72. Ostroff GR, P?ne JJ. Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis. I. Construction and analysis of B. subtilis clone banks in Escherichia coli. Mol Gen Genet. 1984; 193(2):299-305. PMID: 6319967.
      Citations: 11     Fields:    Translation:Cells
    73. Ostroff GR, P?ne JJ. Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis. II. Transfer of sequences propagated in Escherichia coli to B. subtilis. Mol Gen Genet. 1984; 193(2):306-11. PMID: 6319968.
      Citations: 11     Fields:    Translation:Cells
    74. Ostroff GR, P?ne JJ. Molecular cloning with bifunctional plasmid vectors in Bacillus subtilis: isolation of a spontaneous mutant of Bacillus subtilis with enhanced transformability for Escherichia coli-propagated chimeric plasmid DNA. J Bacteriol. 1983 Nov; 156(2):934-6. PMID: 6313628.
      Citations: 40     Fields:    Translation:Cells
    75. Lynfield YL, Ostroff G. Psoriatic flora. Arch Dermatol. 1973 Sep; 108(3):424-5. PMID: 4729769.
      Citations:    Fields:    Translation:HumansCells
    76. Lynfield YL, Ostroff G, Abraham J. Bacteria, skin sterilization, and wound healing in psoriasis. N Y State J Med. 1972 Jun 01; 72(11):1247-50. PMID: 4503897.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    77. ALLEN EG, OSTROFF G, BOVARNICK MR. Inhibition of the cytochrome reductase activity associated with menigopneumonitis virus by fatty acids derived from infected allantoic fluids. Virology. 1960 Aug; 11:737-52. PMID: 13792724.
      Citations:    Fields:    Translation:Cells
    78. LEVEEN HH, FALK G, OSTROFF G, CALEM WS. The production of ulcerative colitis by anticolon sera. Surg Forum. 1960; 11:3-5. PMID: 13761325.
      Citations:    Fields:    Translation:Humans
    79. OSTROFF G, AXELROD DR, BOVARNICK M. Antigenicity of polymers of glutamyl peptide on humans. Proc Soc Exp Biol Med. 1958 Nov; 99(2):345-7. PMID: 13601865.
      Citations: 2     Fields:    Translation:Humans
    80. SCHIER WW, ROTH A, OSTROFF G, SCHRIFT MH. Hodgkin's disease and immunity. Am J Med. 1956 Jan; 20(1):94-9. PMID: 13282926.
      Citations: 39     Fields:    Translation:Humans
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