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Evelyn A Kurt-Jones PhD

InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
364 Plantation Street LRB
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DivisionInfectious Diseases

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentImmunology and Microbiology Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program

    Collapse Biography 
    Collapse education and training
    Tufts University, Medford, MA, United StatesBSBiology
    University of Connecticut, Storrs, CT, United StatesPHDBiomedical Science and Immunol

    Collapse Overview 
    Collapse overview

    Regulation of the innate immune response and its impact on disease

    Evelyn Kurt-JonesResearch in my laboratory is focused on the role of receptor-mediated events in the pathogenesis of infectious and inflammatory processes. The discovery of the Toll-like receptors (TLRs) and their importance in the regulation of host responses to infection has focused attention on the complex interplay between pathogen genes and these host innate immune proteins in determining the outcome of infection. Our studies have demonstrated that pathogen-TLR interactions contribute to early control of infection (macrophage activation, type I interferon), recruitment of immune effector cells (chemokines) and the development of a sustained adaptive immune response (T and B cell activation and maturation). We have focused on host- and pathogen-derived proteins that regulate the magnitude and duration of the innate inflammatory response during viral infection and the impact of these factors on disease severity. Recently we have examined the role of innate immunity in the wound healing and the recruitment of stem cells involved in the regeneration of mucosal tissues. These studies point to the key role of innate immune receptor-triggered pathways in the initiation of healing and repair of damaged tissues following microbial or chemical insults as well as their significant role in disease pathogenesis.

    Collapse Rotation Projects

    Potential Rotation Projects

    1. Expression of Toll-like receptors: Patterns of TLR expression in normal cells. Control of TLR receptor expression by environmental factors and cytokines. TLR expression in diseased tissues.

    2. Role of TLRs in disease pathogenesis: Use of knockout and genetically defined animals to study the role of TLRs in the control of bacterial or viral diseases.

    3. Structure-function studies of TLR signaling: Assessing the signaling activity of wild type and mutant TLRs (altered by site-directed mutageneis) using transient transfection and luciferase reporter gene analysis.

    Collapse Post Docs
    We are seeking a post-doctoral fellow to study toll/interleukin 1 receptors and their role in inflammatory disease pathogenesis using human cells and mouse models.

    Candidates should have a Ph.D. or M.D. degree, or have completed degree requirements. Experience in immunology, molecular biology and/or biochemistry and publication of papers in the areas of cytokine biology, receptor biochemistry and/or cell signaling required.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Besteman SB, Phung E, Raeven HHM, Amatngalim GD, Rumpret M, Crabtree J, Schepp RM, Rodenburg LW, Siemonsma SG, Verleur N, van Slooten R, Duran K, van Haaften GW, Beekman JM, Chang LA, Meyaard L, van der Bruggen T, Berbers GAM, Derksen N, Nierkens S, Morabito KM, Ruckwardt TJ, Kurt-Jones EA, Golenbock D, Graham BS, Bont LJ. Recurrent Respiratory Syncytial Virus Infection in a CD14-Deficient Patient. J Infect Dis. 2022 08 24; 226(2):258-269. PMID: 35429403.
      Citations: 3     Fields:    Translation:HumansCells
    2. Pereira M, Durso DF, Bryant CE, Kurt-Jones EA, Silverman N, Golenbock DT, Gazzinelli RT. The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways. Cell Rep. 2022 08 16; 40(7):111225. PMID: 35977521.
      Citations: 6     Fields:    Translation:HumansCells
    3. Chang CW, Parsi KM, Somasundaran M, Vanderleeden E, Liu P, Cruz J, Cousineau A, Finberg RW, Kurt-Jones EA. A Newly Engineered A549 Cell Line Expressing ACE2 and TMPRSS2 Is Highly Permissive to SARS-CoV-2, Including the Delta and Omicron Variants. Viruses. 2022 06 23; 14(7). PMID: 35891350.
      Citations: 17     Fields:    Translation:HumansCells
    4. Crabtree JN, Caffrey DR, de Souza Silva L, Kurt-Jones EA, Dobbs K, Dent A, Fitzgerald KA, Golenbock DT. Lymphocyte crosstalk is required for monocyte-intrinsic trained immunity to Plasmodium falciparum. J Clin Invest. 2022 06 01; 132(11). PMID: 35642634.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    5. Kurt-Jones EA, Dudek TE, Watanabe D, Mandell L, Che J, Zhou S, Cao L, Greenough T, Babcock GJ, Diaz F, Oh HS, Zhou C, Finberg RW, Knipe DM. Expression of SARS coronavirus 1 spike protein from a herpesviral vector induces innate immune signaling and neutralizing antibody responses. Virology. 2021 07; 559:165-172. PMID: 33930819.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    6. Michael BD, Bricio-Moreno L, Sorensen EW, Miyabe Y, Lian J, Solomon T, Kurt-Jones EA, Luster AD. Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis. Cell Rep. 2020 09 15; 32(11):108150. PMID: 32937134.
      Citations: 44     Fields:    Translation:AnimalsCells
    7. Fulham MA, Ratna A, Gerstein RM, Kurt-Jones EA, Mandrekar P. Alcohol-induced adipose tissue macrophage phenotypic switching is independent of myeloid Toll-like receptor 4 expression. Am J Physiol Cell Physiol. 2019 10 01; 317(4):C687-C700. PMID: 31268779.
      Citations: 5     Fields:    Translation:AnimalsCells
    8. Koupenova M, Corkrey HA, Vitseva O, Manni G, Pang CJ, Clancy L, Yao C, Rade J, Levy D, Wang JP, Finberg RW, Kurt-Jones EA, Freedman JE. The role of platelets in mediating a response to human influenza infection. Nat Commun. 2019 04 16; 10(1):1780. PMID: 30992428.
      Citations: 139     Fields:    Translation:HumansAnimalsCells
    9. Bazzone LE, King M, MacKay CR, Kyawe PP, Meraner P, Lindstrom D, Rojas-Quintero J, Owen CA, Wang JP, Brass AL, Kurt-Jones EA, Finberg RW. A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection. mBio. 2019 02 05; 10(1). PMID: 30723129.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    10. Koupenova M, Mick E, Corkrey HA, Huan T, Clancy L, Shah R, Benjamin EJ, Levy D, Kurt-Jones EA, Tanriverdi K, Freedman JE. Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population. Sci Rep. 2018 04 23; 8(1):6397. PMID: 29686252.
      Citations: 3     Fields:    Translation:HumansCells
    11. Gallego-Marin C, Schrum JE, Andrade WA, Shaffer SA, Giraldo LF, Lasso AM, Kurt-Jones EA, Fitzgerald KA, Golenbock DT. Cyclic GMP-AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria. J Immunol. 2018 01 15; 200(2):768-774. PMID: 29212905.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    12. Kalantari P, Harandi OF, Agarwal S, Rus F, Kurt-Jones EA, Fitzgerald KA, Caffrey DR, Golenbock DT. miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN). J Biol Chem. 2017 04 07; 292(14):5634-5644. PMID: 28209713.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    13. Kurt-Jones EA, Orzalli MH, Knipe DM. Innate Immune Mechanisms and Herpes Simplex Virus Infection and Disease. Adv Anat Embryol Cell Biol. 2017; 223:49-75. PMID: 28528439.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    14. Iracheta-Vellve A, Petrasek J, Gyongyosi B, Satishchandran A, Lowe P, Kodys K, Catalano D, Calenda CD, Kurt-Jones EA, Fitzgerald KA, Szabo G. Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes. J Biol Chem. 2016 Dec 23; 291(52):26794-26805. PMID: 27810900.
      Citations: 70     Fields:    Translation:AnimalsCells
    15. Andrade WA, Firon A, Schmidt T, Hornung V, Fitzgerald KA, Kurt-Jones EA, Trieu-Cuot P, Golenbock DT, Kaminski PA. Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production. Cell Host Microbe. 2016 Jul 13; 20(1):49-59. PMID: 27414497.
      Citations: 65     Fields:    Translation:Cells
    16. Andrade WA, Agarwal S, Mo S, Shaffer SA, Dillard JP, Schmidt T, Hornung V, Fitzgerald KA, Kurt-Jones EA, Golenbock DT. Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4. Cell Rep. 2016 06 14; 15(11):2438-48. PMID: 27264171.
      Citations: 38     Fields:    Translation:HumansCells
    17. Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, Blanco JC, Vogel SN. Novel strategies for targeting innate immune responses to influenza. Mucosal Immunol. 2016 09; 9(5):1173-82. PMID: 26813341.
      Citations: 50     Fields:    Translation:AnimalsCells
    18. Schattgen SA, Gao G, Kurt-Jones EA, Fitzgerald KA. Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2. J Immunol. 2016 Jan 01; 196(1):29-33. PMID: 26590313.
      Citations: 22     Fields:    Translation:AnimalsCells
    19. Ermert D, Shaughnessy J, Joeris T, Kaplan J, Pang CJ, Kurt-Jones EA, Rice PA, Ram S, Blom AM. Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors. PLoS Pathog. 2015 Jul; 11(7):e1005043. PMID: 26200783.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    20. Iracheta-Vellve A, Petrasek J, Satishchandran A, Gyongyosi B, Saha B, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice. J Hepatol. 2015 Nov; 63(5):1147-55. PMID: 26100496.
      Citations: 61     Fields:    Translation:AnimalsCells
    21. Petrasek J, Iracheta-Vellve A, Saha B, Satishchandran A, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease. J Leukoc Biol. 2015 Aug; 98(2):249-56. PMID: 25934928.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    22. Zeldovich KB, Liu P, Renzette N, Foll M, Pham ST, Venev SV, Gallagher GR, Bolon DN, Kurt-Jones EA, Jensen JD, Caffrey DR, Schiffer CA, Kowalik TF, Wang JP, Finberg RW. Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment. Mol Biol Evol. 2015 Jun; 32(6):1519-32. PMID: 25713211.
      Citations: 10     Fields:    Translation:AnimalsCells
    23. Hendricks GL, Velazquez L, Pham S, Qaisar N, Delaney JC, Viswanathan K, Albers L, Comolli JC, Shriver Z, Knipe DM, Kurt-Jones EA, Fygenson DK, Trevejo JM, Wang JP, Finberg RW. Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses. Antiviral Res. 2015 Apr; 116:34-44. PMID: 25637710.
      Citations: 8     Fields:    Translation:AnimalsCells
    24. Thompson MR, Sharma S, Atianand M, Jensen SB, Carpenter S, Knipe DM, Fitzgerald KA, Kurt-Jones EA. Interferon ?-inducible protein (IFI) 16 transcriptionally regulates type i interferons and other interferon-stimulated genes and controls the interferon response to both DNA and RNA viruses. J Biol Chem. 2014 Aug 22; 289(34):23568-81. PMID: 25002588.
      Citations: 70     Fields:    Translation:HumansCells
    25. Davaro F, Forde SD, Garfield M, Jiang Z, Halmen K, Tamburro ND, Kurt-Jones E, Fitzgerald KA, Golenbock DT, Wang D. 3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1? interferes with mature IL-1? signaling. J Biol Chem. 2014 Jun 06; 289(23):16214-22. PMID: 24790079.
      Citations: 13     Fields:    Translation:AnimalsCells
    26. Koupenova M, Vitseva O, MacKay CR, Beaulieu LM, Benjamin EJ, Mick E, Kurt-Jones EA, Ravid K, Freedman JE. Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis. Blood. 2014 Jul 31; 124(5):791-802. PMID: 24755410.
      Citations: 129     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    27. Csak T, Pillai A, Ganz M, Lippai D, Petrasek J, Park JK, Kodys K, Dolganiuc A, Kurt-Jones EA, Szabo G. Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis. Liver Int. 2014 Oct; 34(9):1402-13. PMID: 24650018.
      Citations: 34     Fields:    Translation:AnimalsCells
    28. Severa M, Islam SA, Waggoner SN, Jiang Z, Kim ND, Ryan G, Kurt-Jones E, Charo I, Caffrey DR, Boyartchuk VL, Luster AD, Fitzgerald KA. The transcriptional repressor BLIMP1 curbs host defenses by suppressing expression of the chemokine CCL8. J Immunol. 2014 Mar 01; 192(5):2291-304. PMID: 24477914.
      Citations: 19     Fields:    Translation:AnimalsCells
    29. MacKay CR, Wang JP, Kurt-Jones EA. Dicer's role as an antiviral: still an enigma. Curr Opin Immunol. 2014 Feb; 26:49-55. PMID: 24556400.
      Citations: 15     Fields:    Translation:HumansAnimals
    30. Renzette N, Caffrey DR, Zeldovich KB, Liu P, Gallagher GR, Aiello D, Porter AJ, Kurt-Jones EA, Bolon DN, Poh YP, Jensen JD, Schiffer CA, Kowalik TF, Finberg RW, Wang JP. Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro. J Virol. 2014 Jan; 88(1):272-81. PMID: 24155392.
      Citations: 27     Fields:    Translation:AnimalsCells
    31. Petrasek J, Iracheta-Vellve A, Csak T, Satishchandran A, Kodys K, Kurt-Jones EA, Fitzgerald KA, Szabo G. STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease. Proc Natl Acad Sci U S A. 2013 Oct 08; 110(41):16544-9. PMID: 24052526.
      Citations: 197     Fields:    Translation:AnimalsCells
    32. Lippai D, Bala S, Csak T, Kurt-Jones EA, Szabo G. Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice. PLoS One. 2013; 8(8):e70945. PMID: 23951048.
      Citations: 67     Fields:    Translation:AnimalsCells
    33. Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G. Alcohol-induced IL-1? in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation. J Leukoc Biol. 2013 Jul; 94(1):171-82. PMID: 23625200.
      Citations: 107     Fields:    Translation:AnimalsCells
    34. Vaine CA, Patel MK, Zhu J, Lee E, Finberg RW, Hayward RC, Kurt-Jones EA. Tuning innate immune activation by surface texturing of polymer microparticles: the role of shape in inflammasome activation. J Immunol. 2013 Apr 01; 190(7):3525-32. PMID: 23427254.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    35. Hendricks GL, Weirich KL, Viswanathan K, Li J, Shriver ZH, Ashour J, Ploegh HL, Kurt-Jones EA, Fygenson DK, Finberg RW, Comolli JC, Wang JP. Sialylneolacto-N-tetraose c (LSTc)-bearing liposomal decoys capture influenza A virus. J Biol Chem. 2013 Mar 22; 288(12):8061-8073. PMID: 23362274.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    36. Horan KA, Hansen K, Jakobsen MR, Holm CK, S?by S, Unterholzner L, Thompson M, West JA, Iversen MB, Rasmussen SB, Ellermann-Eriksen S, Kurt-Jones E, Landolfo S, Damania B, Melchjorsen J, Bowie AG, Fitzgerald KA, Paludan SR. Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors. J Immunol. 2013 Mar 01; 190(5):2311-9. PMID: 23345332.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    37. Soberman RJ, MacKay CR, Vaine CA, Ryan GB, Cerny AM, Thompson MR, Nikolic B, Primo V, Christmas P, Sheiffele P, Aronov L, Knipe DM, Kurt-Jones EA. CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2. PLoS One. 2012; 7(10):e47740. PMID: 23082204.
      Citations: 17     Fields:    Translation:AnimalsCells
    38. Petrasek J, Bala S, Csak T, Lippai D, Kodys K, Menashy V, Barrieau M, Min SY, Kurt-Jones EA, Szabo G. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. J Clin Invest. 2012 Oct; 122(10):3476-89. PMID: 22945633.
      Citations: 326     Fields:    Translation:AnimalsCells
    39. Zhou S, Cerny AM, Fitzgerald KA, Kurt-Jones EA, Finberg RW. Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection. J Virol. 2012 Oct; 86(20):11254-65. PMID: 22875973.
      Citations: 20     Fields:    Translation:AnimalsCells
    40. Wills-Karp M, Rani R, Dienger K, Lewkowich I, Fox JG, Perkins C, Lewis L, Finkelman FD, Smith DE, Bryce PJ, Kurt-Jones EA, Wang TC, Sivaprasad U, Hershey GK, Herbert DR. Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. J Exp Med. 2012 Mar 12; 209(3):607-22. PMID: 22329990.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    41. Young JL, Mora A, Cerny A, Czech MP, Woda B, Kurt-Jones EA, Finberg RW, Corvera S. CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone. PLoS One. 2012; 7(1):e29688. PMID: 22253759.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    42. Patel MK, Trombly MI, Kurt-Jones EA. Innate immune responses to Helicobacter pylori infection: an overview. Methods Mol Biol. 2012; 921:205-7. PMID: 23015506.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    43. Patel MK, Ryan GN, Cerny AM, Kurt-Jones EA. Methods for in vivo and in vitro analysis of innate immune responses to Helicobacter pylori infection. Methods Mol Biol. 2012; 921:209-25. PMID: 23015507.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    44. Wang JP, Bowen GN, Zhou S, Cerny A, Zacharia A, Knipe DM, Finberg RW, Kurt-Jones EA. Role of specific innate immune responses in herpes simplex virus infection of the central nervous system. J Virol. 2012 Feb; 86(4):2273-81. PMID: 22171256.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    45. Kriesel JD, Jones BB, Matsunami N, Patel MK, St Pierre CA, Kurt-Jones EA, Finberg RW, Leppert M, Hobbs MR. C21orf91 genotypes correlate with herpes simplex labialis (cold sore) frequency: description of a cold sore susceptibility gene. J Infect Dis. 2011 Dec 01; 204(11):1654-62. PMID: 22039568.
      Citations: 17     Fields:    Translation:HumansCells
    46. St Pierre CA, Leonard D, Corvera S, Kurt-Jones EA, Finberg RW. Antibodies to cell surface proteins redirect intracellular trafficking pathways. Exp Mol Pathol. 2011 Dec; 91(3):723-32. PMID: 21819978.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    47. Thompson MR, Kaminski JJ, Kurt-Jones EA, Fitzgerald KA. Pattern recognition receptors and the innate immune response to viral infection. Viruses. 2011 06; 3(6):920-40. PMID: 21994762.
      Citations: 352     Fields:    Translation:HumansAnimalsCells
    48. Csak T, Velayudham A, Hritz I, Petrasek J, Levin I, Lippai D, Catalano D, Mandrekar P, Dolganiuc A, Kurt-Jones E, Szabo G. Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice. Am J Physiol Gastrointest Liver Physiol. 2011 Mar; 300(3):G433-41. PMID: 21233280.
      Citations: 117     Fields:    Translation:AnimalsCells
    49. Petrasek J, Dolganiuc A, Csak T, Nath B, Hritz I, Kodys K, Catalano D, Kurt-Jones E, Mandrekar P, Szabo G. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology. 2011 Feb; 53(2):649-60. PMID: 21274885.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    50. St Pierre CA, Chan M, Iwakura Y, Ayers DC, Kurt-Jones EA, Finberg RW. Periprosthetic osteolysis: characterizing the innate immune response to titanium wear-particles. J Orthop Res. 2010 Nov; 28(11):1418-24. PMID: 20872576.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    51. McGinnes LW, Gravel KA, Finberg RW, Kurt-Jones EA, Massare MJ, Smith G, Schmidt MR, Morrison TG. Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteins. J Virol. 2011 Jan; 85(1):366-77. PMID: 20980510.
      Citations: 55     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    52. Melo MB, Kasperkovitz P, Cerny A, K?nen-Waisman S, Kurt-Jones EA, Lien E, Beutler B, Howard JC, Golenbock DT, Gazzinelli RT. UNC93B1 mediates host resistance to infection with Toxoplasma gondii. PLoS Pathog. 2010 Aug 26; 6(8):e1001071. PMID: 20865117.
      Citations: 38     Fields:    Translation:AnimalsCells
    53. Petrasek J, Dolganiuc A, Csak T, Kurt-Jones EA, Szabo G. Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology. 2011 Feb; 140(2):697-708.e4. PMID: 20727895.
      Citations: 64     Fields:    Translation:AnimalsCells
    54. van Lint AL, Murawski MR, Goodbody RE, Severa M, Fitzgerald KA, Finberg RW, Knipe DM, Kurt-Jones EA. Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling. J Virol. 2010 Oct; 84(20):10802-11. PMID: 20686034.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    55. Houghton J, Li H, Fan X, Liu Y, Liu JH, Rao VP, Poutahidis T, Taylor CL, Jackson EA, Hewes C, Lyle S, Cerny A, Bowen G, Cerny J, Moore N, Kurt-Jones EA, Erdman SE. Mutations in bone marrow-derived stromal stem cells unmask latent malignancy. Stem Cells Dev. 2010 Aug; 19(8):1153-66. PMID: 20199238.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    56. Zhou S, Cerny AM, Bowen G, Chan M, Knipe DM, Kurt-Jones EA, Finberg RW. Discovery of a novel TLR2 signaling inhibitor with anti-viral activity. Antiviral Res. 2010 Sep; 87(3):295-306. PMID: 20603154.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    57. Zhou S, Cerny AM, Zacharia A, Fitzgerald KA, Kurt-Jones EA, Finberg RW. Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus. J Virol. 2010 Sep; 84(18):9452-62. PMID: 20592086.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    58. Coles AH, Gannon H, Cerny A, Kurt-Jones E, Jones SN. Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity. Proc Natl Acad Sci U S A. 2010 Jun 22; 107(25):11423-8. PMID: 20534538.
      Citations: 30     Fields:    Translation:AnimalsCells
    59. Wang JP, Cerny A, Asher DR, Kurt-Jones EA, Bronson RT, Finberg RW. MDA5 and MAVS mediate type I interferon responses to coxsackie B virus. J Virol. 2010 Jan; 84(1):254-60. PMID: 19846534.
      Citations: 91     Fields:    Translation:AnimalsCells
    60. Murawski MR, McGinnes LW, Finberg RW, Kurt-Jones EA, Massare MJ, Smith G, Heaton PM, Fraire AE, Morrison TG. Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology. J Virol. 2010 Jan; 84(2):1110-23. PMID: 19889768.
      Citations: 81     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    61. Hong EG, Ko HJ, Cho YR, Kim HJ, Ma Z, Yu TY, Friedline RH, Kurt-Jones E, Finberg R, Fischer MA, Granger EL, Norbury CC, Hauschka SD, Philbrick WM, Lee CG, Elias JA, Kim JK. Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes. 2009 Nov; 58(11):2525-35. PMID: 19690064.
      Citations: 185     Fields:    Translation:AnimalsCells
    62. Stoicov C, Fan X, Liu JH, Bowen G, Whary M, Kurt-Jones E, Houghton J. T-bet knockout prevents Helicobacter felis-induced gastric cancer. J Immunol. 2009 Jul 01; 183(1):642-9. PMID: 19535625.
      Citations: 14     Fields:    Translation:AnimalsCells
    63. Li H, Fan X, Stoicov C, Liu JH, Zubair S, Tsai E, Ste Marie R, Wang TC, Lyle S, Kurt-Jones E, Houghton J. Human and mouse colon cancer utilizes CD95 signaling for local growth and metastatic spread to liver. Gastroenterology. 2009 Sep; 137(3):934-44, 944.e1-4. PMID: 19524576.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    64. Sharif R, Dawra R, Wasiluk K, Phillips P, Dudeja V, Kurt-Jones E, Finberg R, Saluja A. Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice. Gut. 2009 Jun; 58(6):813-9. PMID: 19201771.
      Citations: 80     Fields:    Translation:AnimalsCells
    65. Zhou S, Kurt-Jones EA, Cerny AM, Chan M, Bronson RT, Finberg RW. MyD88 intrinsically regulates CD4 T-cell responses. J Virol. 2009 Feb; 83(4):1625-34. PMID: 19052080.
      Citations: 34     Fields:    Translation:AnimalsCells
    66. Murawski MR, Bowen GN, Cerny AM, Anderson LJ, Haynes LM, Tripp RA, Kurt-Jones EA, Finberg RW. Respiratory syncytial virus activates innate immunity through Toll-like receptor 2. J Virol. 2009 Feb; 83(3):1492-500. PMID: 19019963.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    67. Tu S, Bhagat G, Cui G, Takaishi S, Kurt-Jones EA, Rickman B, Betz KS, Penz-Oesterreicher M, Bjorkdahl O, Fox JG, Wang TC. Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell. 2008 Nov 04; 14(5):408-19. PMID: 18977329.
      Citations: 406     Fields:    Translation:AnimalsCells
    68. Hritz I, Velayudham A, Dolganiuc A, Kodys K, Mandrekar P, Kurt-Jones E, Szabo G. Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion. Hepatology. 2008 Oct; 48(4):1342-7. PMID: 18798338.
      Citations: 17     Fields:    Translation:AnimalsCells
    69. Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc A, Kodys K, Kurt-Jones E, Szabo G. The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. Hepatology. 2008 Oct; 48(4):1224-31. PMID: 18792393.
      Citations: 220     Fields:    Translation:AnimalsCells
    70. Liu X, Fitzgerald K, Kurt-Jones E, Finberg R, Knipe DM. Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11335-9. PMID: 18682563.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    71. Wang JP, Bowen GN, Padden C, Cerny A, Finberg RW, Newburger PE, Kurt-Jones EA. Toll-like receptor-mediated activation of neutrophils by influenza A virus. Blood. 2008 Sep 01; 112(5):2028-34. PMID: 18544685.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    72. Zhou S, Halle A, Kurt-Jones EA, Cerny AM, Porpiglia E, Rogers M, Golenbock DT, Finberg RW. Lymphocytic choriomeningitis virus (LCMV) infection of CNS glial cells results in TLR2-MyD88/Mal-dependent inflammatory responses. J Neuroimmunol. 2008 Feb; 194(1-2):70-82. PMID: 18295350.
      Citations: 48     Fields:    Translation:AnimalsCells
    73. Thornley TB, Phillips NE, Beaudette-Zlatanova BC, Markees TG, Bahl K, Brehm MA, Shultz LD, Kurt-Jones EA, Mordes JP, Welsh RM, Rossini AA, Greiner DL. Type 1 IFN mediates cross-talk between innate and adaptive immunity that abrogates transplantation tolerance. J Immunol. 2007 Nov 15; 179(10):6620-9. PMID: 17982052.
      Citations: 40     Fields:    Translation:AnimalsCells
    74. Li H, Fan X, Kovi RC, Jo Y, Moquin B, Konz R, Stoicov C, Kurt-Jones E, Grossman SR, Lyle S, Rogers AB, Montrose M, Houghton J. Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: a model of age-related tumorigenesis in mice. Cancer Res. 2007 Nov 15; 67(22):10889-98. PMID: 18006834.
      Citations: 85     Fields:    Translation:AnimalsCells
    75. Sarangi PP, Kim B, Kurt-Jones E, Rouse BT. Innate recognition network driving herpes simplex virus-induced corneal immunopathology: role of the toll pathway in early inflammatory events in stromal keratitis. J Virol. 2007 Oct; 81(20):11128-38. PMID: 17686871.
      Citations: 54     Fields:    Translation:AnimalsCells
    76. Finberg RW, Kurt-Jones EA. Tolls: you pay them on the way in and on the way out! J Infect Dis. 2007 Aug 15; 196(4):497-8. PMID: 17624831.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    77. Wang JP, Kurt-Jones EA, Finberg RW. Innate immunity to respiratory viruses. Cell Microbiol. 2007 Jul; 9(7):1641-6. PMID: 17506818.
      Citations: 25     Fields:    Translation:HumansCells
    78. Zhou S, Kurt-Jones EA, Fitzgerald KA, Wang JP, Cerny AM, Chan M, Finberg RW. Role of MyD88 in route-dependent susceptibility to vesicular stomatitis virus infection. J Immunol. 2007 Apr 15; 178(8):5173-81. PMID: 17404300.
      Citations: 20     Fields:    Translation:AnimalsCells
    79. Wang JP, Asher DR, Chan M, Kurt-Jones EA, Finberg RW. Cutting Edge: Antibody-mediated TLR7-dependent recognition of viral RNA. J Immunol. 2007 Mar 15; 178(6):3363-7. PMID: 17339429.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    80. Finberg RW, Wang JP, Kurt-Jones EA. Toll like receptors and viruses. Rev Med Virol. 2007 Jan-Feb; 17(1):35-43. PMID: 17146842.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    81. Kurt-Jones EA, Cao L, Sandor F, Rogers AB, Whary MT, Nambiar PR, Cerny A, Bowen G, Yan J, Takaishi S, Chi AL, Reed G, Houghton J, Fox JG, Wang TC. Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses. Infect Immun. 2007 Jan; 75(1):471-80. PMID: 17101660.
      Citations: 43     Fields:    Translation:AnimalsCells
    82. Velayudham A, Hritz I, Dolganiuc A, Mandrekar P, Kurt-Jones E, Szabo G. Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury. J Hepatol. 2006 Dec; 45(6):813-24. PMID: 16935388.
      Citations: 23     Fields:    Translation:Animals
    83. Szomolanyi-Tsuda E, Liang X, Welsh RM, Kurt-Jones EA, Finberg RW. Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo. J Virol. 2006 May; 80(9):4286-91. PMID: 16611887.
      Citations: 66     Fields:    Translation:AnimalsCells
    84. Finberg RW, Kurt-Jones EA. CD14: chaperone or matchmaker? Immunity. 2006 Feb; 24(2):127-9. PMID: 16473824.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    85. Romics L, Dolganiuc A, Velayudham A, Kodys K, Mandrekar P, Golenbock D, Kurt-Jones E, Szabo G. Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes. J Leukoc Biol. 2005 Dec; 78(6):1255-64. PMID: 16204620.
      Citations: 15     Fields:    Translation:AnimalsCells
    86. Wang JP, Kurt-Jones EA, Shin OS, Manchak MD, Levin MJ, Finberg RW. Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2. J Virol. 2005 Oct; 79(20):12658-66. PMID: 16188968.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    87. Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, Finberg RW, Tarakhovsky A, Vogel SN, Belkaid Y, Kurt-Jones EA, Karp CL. Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol. 2005 Jun; 6(6):571-8. PMID: 15852007.
      Citations: 160     Fields:    Translation:HumansAnimalsCells
    88. Zhou S, Kurt-Jones EA, Mandell L, Cerny A, Chan M, Golenbock DT, Finberg RW. MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection. Eur J Immunol. 2005 Mar; 35(3):822-30. PMID: 15724245.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    89. Kurt-Jones EA, Belko J, Yu C, Newburger PE, Wang J, Chan M, Knipe DM, Finberg RW. The role of toll-like receptors in herpes simplex infection in neonates. J Infect Dis. 2005 Mar 01; 191(5):746-8. PMID: 15688290.
      Citations: 42     Fields:    Translation:HumansCells
    90. Divanovic S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, Finberg RW, Tarakhovsky A, Vogel SN, Belkaid Y, Kurt-Jones EA, Karp CL. Inhibition of TLR-4/MD-2 signaling by RP105/MD-1. J Endotoxin Res. 2005; 11(6):363-8. PMID: 16303092.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    91. Finberg RW, Knipe DM, Kurt-Jones EA. Herpes simplex virus and toll-like receptors. Viral Immunol. 2005; 18(3):457-65. PMID: 16212524.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    92. Finberg RW, Kurt-Jones EA. Viruses and Toll-like receptors. Microbes Infect. 2004 Dec; 6(15):1356-60. PMID: 15596120.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    93. Dolganiuc A, Oak S, Kodys K, Golenbock DT, Finberg RW, Kurt-Jones E, Szabo G. Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation. Gastroenterology. 2004 Nov; 127(5):1513-24. PMID: 15521019.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
    94. Mandell L, Moran AP, Cocchiarella A, Houghton J, Taylor N, Fox JG, Wang TC, Kurt-Jones EA. Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4. Infect Immun. 2004 Nov; 72(11):6446-54. PMID: 15501775.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    95. Murphy TJ, Paterson HM, Kriynovich S, Zang Y, Kurt-Jones EA, Mannick JA, Lederer JA. Linking the "two-hit" response following injury to enhanced TLR4 reactivity. J Leukoc Biol. 2005 Jan; 77(1):16-23. PMID: 15496450.
      Citations: 33     Fields:    Translation:AnimalsCells
    96. Kurt-Jones EA, Chan M, Zhou S, Wang J, Reed G, Bronson R, Arnold MM, Knipe DM, Finberg RW. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A. 2004 Feb 03; 101(5):1315-20. PMID: 14739339.
      Citations: 266     Fields:    Translation:HumansAnimalsCells
    97. Kurt-Jones EA, Sandor F, Ortiz Y, Bowen GN, Counter SL, Wang TC, Finberg RW. Use of murine embryonic fibroblasts to define Toll-like receptor activation and specificity. J Endotoxin Res. 2004; 10(6):419-24. PMID: 15588425.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    98. Finberg RW, Re F, Popova L, Golenbock DT, Kurt-Jones EA. Cell activation by Toll-like receptors: role of LBP and CD14. J Endotoxin Res. 2004; 10(6):413-8. PMID: 15588424.
      Citations: 12     Fields:    Translation:HumansCells
    99. Sandor F, Latz E, Re F, Mandell L, Repik G, Golenbock DT, Espevik T, Kurt-Jones EA, Finberg RW. Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling. J Cell Biol. 2003 Sep 15; 162(6):1099-110. PMID: 12975352.
      Citations: 36     Fields:    Translation:HumansCells
    100. Compton T, Kurt-Jones EA, Boehme KW, Belko J, Latz E, Golenbock DT, Finberg RW. Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J Virol. 2003 Apr; 77(8):4588-96. PMID: 12663765.
      Citations: 276     Fields:    Translation:HumansAnimalsCells
    101. Malley R, Henneke P, Morse SC, Cieslewicz MJ, Lipsitch M, Thompson CM, Kurt-Jones E, Paton JC, Wessels MR, Golenbock DT. Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1966-71. PMID: 12569171.
      Citations: 272     Fields:    Translation:AnimalsCells
    102. Kurt-Jones EA, Mandell L, Whitney C, Padgett A, Gosselin K, Newburger PE, Finberg RW. Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils. Blood. 2002 Sep 01; 100(5):1860-8. PMID: 12176910.
      Citations: 97     Fields:    Translation:HumansCells
    103. Haynes LM, Moore DD, Kurt-Jones EA, Finberg RW, Anderson LJ, Tripp RA. Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus. J Virol. 2001 Nov; 75(22):10730-7. PMID: 11602714.
      Citations: 193     Fields:    Translation:AnimalsCells
    104. Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, Finberg RW. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol. 2000 Nov; 1(5):398-401. PMID: 11062499.
      Citations: 585     Fields:    Translation:HumansAnimalsCells
    105. Asea A, Kraeft SK, Kurt-Jones EA, Stevenson MA, Chen LB, Finberg RW, Koo GC, Calderwood SK. HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med. 2000 Apr; 6(4):435-42. PMID: 10742151.
      Citations: 489     Fields:    Translation:HumansCells
    106. Kol A, Lichtman AH, Finberg RW, Libby P, Kurt-Jones EA. Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. J Immunol. 2000 Jan 01; 164(1):13-7. PMID: 10604986.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    107. Solomon KR, Kurt-Jones EA, Saladino RA, Stack AM, Dunn IF, Ferretti M, Golenbock D, Fleisher GR, Finberg RW. Heterotrimeric G proteins physically associated with the lipopolysaccharide receptor CD14 modulate both in vivo and in vitro responses to lipopolysaccharide. J Clin Invest. 1998 Dec 01; 102(11):2019-27. PMID: 9835628.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    108. Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science. 1997 Feb 28; 275(5304):1320-3. PMID: 9036860.
      Citations: 968     Fields:    Translation:HumansAnimalsCells
    109. Hafler DA, Chofflon M, Kurt-Jones E, Weiner HL. Interleukin-1 corrects the defective autologous mixed lymphocyte response in multiple sclerosis. Clin Immunol Immunopathol. 1991 Jan; 58(1):115-25. PMID: 1670583.
      Citations: 3     Fields:    Translation:HumansCells
    110. Leung DY, Cotran RS, Kurt-Jones E, Burns JC, Newburger JW, Pober JS. Endothelial cell activation and high interleukin-1 secretion in the pathogenesis of acute Kawasaki disease. Lancet. 1989 Dec 02; 2(8675):1298-302. PMID: 2480498.
      Citations: 90     Fields:    Translation:Humans
    111. Leung DY, Cotran RS, Kurt-Jones E, Burns JC, Newburger JW, Pober JS. Endothelial activation in the pathogenesis of Kawasaki disease. Trans Assoc Am Physicians. 1989; 102:131-8. PMID: 2484114.
      Citations: 2     Fields:    Translation:Humans
    112. Kurt-Jones EA, Liano D, HayGlass KA, Benacerraf B, Sy MS, Abbas AK. The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice. J Immunol. 1988 Jun 01; 140(11):3773-8. PMID: 2453554.
      Citations: 66     Fields:    Translation:AnimalsCells
    113. Kurt-Jones EA, Hamberg S, Ohara J, Paul WE, Abbas AK. Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness. J Exp Med. 1987 Dec 01; 166(6):1774-87. PMID: 2960773.
      Citations: 70     Fields:    Translation:AnimalsCells
    114. Kurt-Jones EA, Fiers W, Pober JS. Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts. J Immunol. 1987 Oct 01; 139(7):2317-24. PMID: 3116078.
      Citations: 46     Fields:    Translation:HumansCells
    115. Lichtman AH, Kurt-Jones EA, Abbas AK. B-cell stimulatory factor 1 and not interleukin 2 is the autocrine growth factor for some helper T lymphocytes. Proc Natl Acad Sci U S A. 1987 Feb; 84(3):824-7. PMID: 2949327.
      Citations: 31     Fields:    Translation:AnimalsCells
    116. Kurt-Jones EA, Virgin HW, Unanue ER. In vivo and in vitro expression of macrophage membrane interleukin 1 in response to soluble and particulate stimuli. J Immunol. 1986 Jul 01; 137(1):10-4. PMID: 3086442.
      Citations: 20     Fields:    Translation:AnimalsCells
    117. Kurt-Jones EA, Virgin HW, Unanue ER. Relationship of macrophage Ia and membrane IL 1 expression to antigen presentation. J Immunol. 1985 Dec; 135(6):3652-4. PMID: 3934262.
      Citations: 20     Fields:    Translation:AnimalsCells
    118. Virgin HW, Kurt-Jones EA, Wittenberg GF, Unanue ER. Immune complex effects on murine macrophages. II. Immune complex effects on activated macrophages cytotoxicity, membrane IL 1, and antigen presentation. J Immunol. 1985 Dec; 135(6):3744-9. PMID: 3877753.
      Citations: 5     Fields:    Translation:AnimalsCells
    119. Kurt-Jones EA, Kiely JM, Unanue ER. Conditions required for expression of membrane IL 1 on B cells. J Immunol. 1985 Sep; 135(3):1548-50. PMID: 3874900.
      Citations: 22     Fields:    Translation:AnimalsCells
    120. Kurt-Jones EA, Beller DI, Mizel SB, Unanue ER. Identification of a membrane-associated interleukin 1 in macrophages. Proc Natl Acad Sci U S A. 1985 Feb; 82(4):1204-8. PMID: 3919388.
      Citations: 129     Fields:    Translation:AnimalsCells
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