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Rohit Sharma PhD

TitleAdjunct Assistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMedicine
AddressUniversity of Massachusetts Medical School
55 Lake Ave North
Worcester MA 01605
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMedicine
    DivisionDiabetes


    Collapse Biography 
    Collapse education and training
    Panjab University, Chandigargh, CH, IndiaBSBiochemistry
    Panjab University, Chandigargh, CH, IndiaMSBiochemistry
    Postgraduate Institute of Medical Education and Research, Chandigargh, CH, IndiaPHDMolecular Biology & Biochem

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Snyder JT, Darko C, Sharma RB, Alonso LC. Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse ß-Cells. Front Endocrinol (Lausanne). 2021; 12:734079. PMID: 34531828.
      View in: PubMed
    2. Sharma RB, Snyder JT, Alonso LC. Atf6a impacts cell number by influencing survival, death and proliferation. Mol Metab. 2019 Sep; 27S:S69-S80. PMID: 31500833.
      View in: PubMed
    3. Pawaria S, Nündel K, Gao KM, Moses S, Busto P, Holt K, Sharma RB, Brehm MA, Gravallese EM, Socolovsky M, Christ A, Marshak-Rothstein A. The Role of IFN?-Producing Th1 Cells in a Type I IFN-Independent Murine Model of Autoinflammation Resulting from DNase II-Deficiency. Arthritis Rheumatol. 2019 Aug 28. PMID: 31464028.
      View in: PubMed
    4. Sharma RB, Darko C, Zheng X, Gablaski B, Alonso LC. DNA Damage Does Not Cause BrdU Labeling of Mouse or Human Beta Cells. Diabetes. 2019 Mar 04. PMID: 30833468.
      View in: PubMed
    5. Kong Y, Sharma RB, Ly S, Stamateris RE, Jesdale WM, Alonso LC. CDKN2A/B T2D GWAS Risk-SNPs Impact Locus Gene Expression and Proliferation in Human Islets. Diabetes. 2018 Feb 06. PMID: 29432124.
      View in: PubMed
    6. Roth Flach RJ, Danai LV, DiStefano MT, Kelly M, Menendez LG, Jurczyk A, Sharma RB, Jung DY, Kim JH, Kim JK, Bortell R, Alonso LC, Czech MP. Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia. J Biol Chem. 2016 Jul 29; 291(31):16221-30. PMID: 27226575.
      View in: PubMed
    7. Kong Y, Sharma RB, Nwosu BU, Alonso LC. Islet biology, the CDKN2A/B locus and type 2 diabetes risk. Diabetologia. 2016 Aug; 59(8):1579-93. PMID: 27155872.
      View in: PubMed
    8. Choudhury SR, Fitzpatrick Z, Harris AF, Maitland SA, Ferreira JS, Zhang Y, Ma S, Sharma RB, Gray-Edwards HL, Johnson JA, Johnson AK, Alonso LC, Punzo C, Wagner KR, Maguire CA, Kotin RM, Martin DR, Sena-Esteves M. In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy. Mol Ther. 2016 Aug; 24(7):1247-57. PMID: 27117222.
      View in: PubMed
    9. Stamateris RE, Sharma RB, Kong Y, Ebrahimpour P, Panday D, Ranganath P, Zou B, Levitt H, Parambil NA, O'Donnell CP, García-Ocaña A, Alonso LC. Glucose Induces Mouse ß-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor. Diabetes. 2016 Apr; 65(4):981-95. PMID: 26740601.
      View in: PubMed
    10. Sharma RB, O'Donnell AC, Stamateris RE, Ha B, McCloskey KM, Reynolds PR, Arvan P, Alonso LC. Insulin demand regulates ß cell number via the unfolded protein response. J Clin Invest. 2015 Oct 1; 125(10):3831-46. PMID: 26389675.
      View in: PubMed
    11. Singamsetty S, Shah FA, Guo L, Watanabe Y, McDonald S, Sharma R, Zhang Y, Alonso LC, O'Donnell CP, McVerry BJ. Early initiation of low-level parenteral dextrose induces an accelerated diabetic phenotype in septic C57BL/6J mice. Appl Physiol Nutr Metab. 2016 Jan; 41(1):12-9. PMID: 26624964.
      View in: PubMed
    12. Sharma RB, Alonso LC. Lipotoxicity in the pancreatic beta cell: not just survival and function, but proliferation as well? Curr Diab Rep. 2014 Jun; 14(6):492. PMID: 24740729.
      View in: PubMed
    13. Sharma RB, Wang Q, Khillan JS. Amplification of tumor inducing putative cancer stem cells (CSCs) by vitamin A/retinol from mammary tumors. Biochem Biophys Res Commun. 2013 Jul 12; 436(4):625-31. PMID: 23764401.
      View in: PubMed
    14. Stamateris RE, Sharma RB, Hollern DA, Alonso LC. Adaptive ß-cell proliferation increases early in high-fat feeding in mice, concurrent with metabolic changes, with induction of islet cyclin D2 expression. Am J Physiol Endocrinol Metab. 2013 Jul 1; 305(1):E149-59. PMID: 23673159.
      View in: PubMed
    15. Qiu W, Wang X, Buchanan M, He K, Sharma R, Zhang L, Wang Q, Yu J. ADAR1 is essential for intestinal homeostasis and stem cell maintenance. Cell Death Dis. 2013 Apr 18; 4:e599. PMID: 23598411; PMCID: PMC3641348.
      View in: PubMed, PubMed Central
    16. Yu S, Sharma R, Nie D, Jiao H, Im HJ, Lai Y, Zhao Z, Zhu K, Fan J, Chen D, Wang Q, Xiao G. ADAR1 ablation decreases bone mass by impairing osteoblast function in mice. Gene. 2013 Jan 15; 513(1):101-10. PMID: 23123729; PMCID: PMC3514579.
      View in: PubMed, PubMed Central
    17. Bhatia H, Sharma R, Dawes J, Khillan JS. Maintenance of feeder free anchorage independent cultures of ES and iPS cells by retinol/vitamin A. J Cell Biochem. 2012 Sep; 113(9):3002-10. PMID: 22566007.
      View in: PubMed
    18. Sharma R, Wang Y, Zhou P, Steinman RA, Wang Q. An essential role of RNA editing enzyme ADAR1 in mouse skin. J Dermatol Sci. 2011 Oct; 64(1):70-2. PMID: 21788117.
      View in: PubMed
    19. Arora SK, Sharma R, Kaur G, Bhoria P, Sharma M, Luthra-Guptasarma M. Towards an indirect screening technique facilitating detection of cellular populations bearing specific cell surface markers. Biotechnol Prog. 2010 Nov-Dec; 26(6):1544-50. PMID: 20878645.
      View in: PubMed
    20. Taurog JD, Dorris ML, Satumtira N, Tran TM, Sharma R, Dressel R, van den Brandt J, Reichardt HM. Spondylarthritis in HLA-B27/human beta2-microglobulin-transgenic rats is not prevented by lack of CD8. Arthritis Rheum. 2009 Jul; 60(7):1977-84. PMID: 19565478.
      View in: PubMed
    21. Sharma R, Vasishta RK, Sen RK, Luthra-Guptasarma M. Refolding of HLA-B27 heavy chains in the absence of beta2m yields stable high molecular weight (HMW) protein forms displaying native-like as well as non-native-like conformational features: implications for autoimmune disease. Biochim Biophys Acta. 2007 Dec; 1772(11-12):1258-69. PMID: 18036353.
      View in: PubMed
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