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Brendan Michael O'Leary PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentProgram in Molecular Medicine
AddressUniversity of Massachusetts Medical School
55 Lake Ave North
Worcester MA 01605
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentProgram in Molecular Medicine

    Collapse Biography 
    Collapse education and training
    Middlebury College, Middlebury, VT, United StatesBAChemistry
    Massachusetts Institute of Technology, Cambridge, MA, United StatesPHDOrganic Chemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ivanova A, O Leary B, Signorelli S, Falconet D, Moyankova D, Whelan J, Djilianov D, Murcha MW. Mitochondrial activity and biogenesis during resurrection of Haberlea rhodopensis. New Phytol. 2022 Jul 24. PMID: 35872573.
      Citations:    Fields:    
    2. Oh GGK, O'Leary BM, Signorelli S, Millar AH. Alternative oxidase (AOX) 1a and 1d limit proline-induced oxidative stress and aid salinity recovery in Arabidopsis. Plant Physiol. 2022 03 04; 188(3):1521-1536. PMID: 34919733.
      Citations: 3     Fields:    Translation:AnimalsCells
    3. O'Leary BM. Guarding the gates: TOR mediates guard cell starch degradation to control stomatal opening. Plant Cell. 2022 03 04; 34(3):953-954. PMID: 35243511.
      Citations:    Fields:    Translation:AnimalsCells
    4. O'Leary BM. Survival or starvation: SnRK1 controls rate of resource use in pre-photosynthetic seedlings. Plant Cell. 2022 01 20; 34(1):501-502. PMID: 35226745.
      Citations:    Fields:    Translation:Animals
    5. O'Leary BM, Oh GGK, Millar AH. High-Throughput Oxygen Consumption Measurements in Leaf Tissue Using Oxygen Sensitive Fluorophores. Methods Mol Biol. 2022; 2363:63-75. PMID: 34545486.
      Citations: 1     Fields:    Translation:Cells
    6. O'Leary BM. Swapping acids: the ins and outs of plant mitochondrial metabolism. Plant Cell. 2021 12 03; 33(12):3608-3609. PMID: 35231126.
      Citations:    Fields:    Translation:AnimalsCells
    7. O'Leary BM. Circular permutation of concanavalin A: why the rarest protein modification in nature came to be. Plant Cell. 2021 08 31; 33(8):2521-2522. PMID: 35233625.
      Citations:    Fields:    
    8. O'Leary BM. Playing with Pyr: alternate sources of mitochondrial pyruvate fuel plant respiration. Plant Cell. 2021 08 31; 33(8):2519-2520. PMID: 35233626.
      Citations:    Fields:    Translation:AnimalsCells
    9. Amin ND, Senturk G, Costaguta G, Driscoll S, O'Leary B, Bonanomi D, Pfaff SL. A hidden threshold in motor neuron gene networks revealed by modulation of miR-218 dose. Neuron. 2021 10 20; 109(20):3252-3267.e6. PMID: 34450025.
      Citations: 2     Fields:    Translation:AnimalsCells
    10. Broda M, Khan K, O'Leary B, Pružinská A, Lee CP, Millar AH, Van Aken O. Increased expression of ANAC017 primes for accelerated senescence. Plant Physiol. 2021 08 03; 186(4):2205-2221. PMID: 33914871.
      Citations: 2     Fields:    Translation:Animals
    11. O'Leary BM. Artificial sweetening: domestication of carbohydrate mobilization in watermelon. Plant Cell. 2021 07 02; 33(5):1405-1406. PMID: 35234949.
      Citations:    Fields:    Translation:Animals
    12. O'Leary BM. The Lure of Lignin: Deciphering High-value Lignin Formation in Seed Coats. Plant Cell. 2020 12; 32(12):3652-3653. PMID: 33077492.
      Citations: 1     Fields:    Translation:AnimalsCells
    13. O'Leary BM, Scafaro AP, Fenske R, Duncan O, Ströher E, Petereit J, Millar AH. Rubisco lysine acetylation occurs at very low stoichiometry in mature Arabidopsis leaves: implications for regulation of enzyme function. Biochem J. 2020 10 16; 477(19):3885-3896. PMID: 32959870.
      Citations: 1     Fields:    Translation:AnimalsCells
    14. O'Leary BM. Feasting While Fasting: How Autophagy Helps Maize Survive Carbon Starvation. Plant Cell. 2020 09; 32(9):2663-2664. PMID: 32665306.
      Citations:    Fields:    Translation:AnimalsCells
    15. O'Leary BM. Breaking the Mold: Reduced Protein Storage in Brassica napus Seed Triggers Unexpected Structural Changes. Plant Cell. 2020 07; 32(7):2077-2078. PMID: 32385104.
      Citations:    Fields:    Translation:Animals
    16. O'Leary B, Plaxton WC. Multifaceted functions of post-translational enzyme modifications in the control of plant glycolysis. Curr Opin Plant Biol. 2020 06; 55:28-37. PMID: 32200227.
      Citations: 6     Fields:    Translation:AnimalsCells
    17. Salih KJ, Duncan O, Li L, O'Leary B, Fenske R, Trösch J, Millar AH. Impact of oxidative stress on the function, abundance, and turnover of the Arabidopsis 80S cytosolic ribosome. Plant J. 2020 07; 103(1):128-139. PMID: 32027433.
      Citations: 6     Fields:    Translation:AnimalsCells
    18. O'Leary BM. Another Brick in the Plant Cell Wall: Characterization of Arabidopsis CSLD3 Function in Cell Wall Synthesis. Plant Cell. 2020 05; 32(5):1359-1360. PMID: 32169958.
      Citations:    Fields:    Translation:AnimalsCells
    19. O'Leary BM. The Case of Virus-Induced Plant Autophagy: Cui Bono? Plant Cell. 2020 04; 32(4):805-806. PMID: 32051212.
      Citations:    Fields:    Translation:Cells
    20. O'Leary BM, Oh GGK, Lee CP, Millar AH. Metabolite Regulatory Interactions Control Plant Respiratory Metabolism via Target of Rapamycin (TOR) Kinase Activation. Plant Cell. 2020 03; 32(3):666-682. PMID: 31888967.
      Citations: 17     Fields:    Translation:AnimalsCells
    21. O'Leary BM, Asao S, Millar AH, Atkin OK. Core principles which explain variation in respiration across biological scales. New Phytol. 2019 04; 222(2):670-686. PMID: 30394553.
      Citations: 19     Fields:    Translation:AnimalsCells
    22. O'Leary BM, Lee CP, Atkin OK, Cheng R, Brown TB, Millar AH. Variation in Leaf Respiration Rates at Night Correlates with Carbohydrate and Amino Acid Supply. Plant Physiol. 2017 Aug; 174(4):2261-2273. PMID: 28615345.
      Citations: 17     Fields:    Translation:AnimalsCells
    23. Scafaro AP, Negrini ACA, O'Leary B, Rashid FAA, Hayes L, Fan Y, Zhang Y, Chochois V, Badger MR, Millar AH, Atkin OK. The combination of gas-phase fluorophore technology and automation to enable high-throughput analysis of plant respiration. Plant Methods. 2017; 13:16. PMID: 28344635.
    24. O'Leary BM, Neale HC, Geilfus CM, Jackson RW, Arnold DL, Preston GM. Early changes in apoplast composition associated with defence and disease in interactions between Phaseolus vulgaris and the halo blight pathogen Pseudomonas syringae Pv. phaseolicola. Plant Cell Environ. 2016 10; 39(10):2172-84. PMID: 27239727.
      Citations: 34     Fields:    Translation:AnimalsCells
    25. O'Leary BM, Rico A, McCraw S, Fones HN, Preston GM. The infiltration-centrifugation technique for extraction of apoplastic fluid from plant leaves using Phaseolus vulgaris as an example. J Vis Exp. 2014 Dec 19; (94). PMID: 25549068.
      Citations: 32     Fields:    Translation:AnimalsCells
    26. O'Leary B, Preston GM, Sweetlove LJ. Increased ?-cyanoalanine nitrilase activity improves cyanide tolerance and assimilation in Arabidopsis. Mol Plant. 2014 Jan; 7(1):231-43. PMID: 23825089.
      Citations: 8     Fields:    Translation:AnimalsPHPublic Health
    27. O'Leary B, Park J, Plaxton WC. The remarkable diversity of plant PEPC (phosphoenolpyruvate carboxylase): recent insights into the physiological functions and post-translational controls of non-photosynthetic PEPCs. Biochem J. 2011 May 15; 436(1):15-34. PMID: 21524275.
      Citations: 88     Fields:    Translation:AnimalsCells
    28. O'Leary B, Rao SK, Plaxton WC. Phosphorylation of bacterial-type phosphoenolpyruvate carboxylase at Ser425 provides a further tier of enzyme control in developing castor oil seeds. Biochem J. 2011 Jan 01; 433(1):65-74. PMID: 20950272.
      Citations: 6     Fields:    Translation:AnimalsCells
    29. Uhrig RG, O'Leary B, Spang HE, MacDonald JA, She YM, Plaxton WC. Coimmunopurification of phosphorylated bacterial- and plant-type phosphoenolpyruvate carboxylases with the plastidial pyruvate dehydrogenase complex from developing castor oil seeds. Plant Physiol. 2008 Mar; 146(3):1346-57. PMID: 18184736.
      Citations: 12     Fields:    Translation:AnimalsCells
    30. Szabo T, O'Leary BM, Rebek J. Self-Assembling Sieves. Angew Chem Int Ed Engl. 1998 Dec 31; 37(24):3410-3413. PMID: 29711288.
      Citations:    Fields:    
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