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Mark Damone Johnson MD, PhD

TitleChair and Professor
Endowed TitleMaroun Semaan Chair in Neurosurgery
InstitutionUMass Chan Medical School
DepartmentNeurological Surgery
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentNeurological Surgery

    InstitutionT.H. Chan School of Medicine
    DepartmentNeuroNexus Institute

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentCancer Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMillennium MD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentNeuroscience

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentTranslational Science


    Collapse Biography 
    Collapse education and training
    Amherst College, Amherst, MA, United StatesBAChemistry
    Harvard Medical School, Boston, MA, United StatesMD
    Harvard University, Cambridge, MA, United StatesPHDNeurobiology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Arvold ND, Shi DD, Aizer AA, Norden AD, Reardon DA, Lee EQ, Nayak L, Dunn IF, Golby AJ, Johnson MD, Claus EB, Chiocca EA, Ligon KL, Wen PY, Alexander BM. Salvage re-irradiation for recurrent high-grade glioma and comparison to bevacizumab alone. J Neurooncol. 2017 Dec; 135(3):581-591. PMID: 28975467.
      Citations: 9     Fields:    Translation:Humans
    2. Hickman TT, Shuman ME, Johnson TA, Yang F, Rice RR, Rice IM, Chung EH, Wiemann R, Tinl M, Iracheta C, Chen G, Flynn P, Mondello MB, Thompson J, Meadows ME, Carroll RS, Yang HW, Xing H, Pilgrim D, Chiocca EA, Dunn IF, Golby AJ, Johnson MD. Association between shunt-responsive idiopathic normal pressure hydrocephalus and alcohol. J Neurosurg. 2017 Aug; 127(2):240-248. PMID: 27689463.
      Citations: 8     Fields:    Translation:Humans
    3. Yang F, Hickman TT, Tinl M, Iracheta C, Chen G, Flynn P, Shuman ME, Johnson TA, Rice RR, Rice IM, Wiemann R, Johnson MD. Quantitative evaluation of changes in gait after extended cerebrospinal fluid drainage for normal pressure hydrocephalus. J Clin Neurosci. 2016 Jun; 28:31-7. PMID: 26775149.
      Citations: 8     Fields:    Translation:Humans
    4. Wade JH, Alsop AT, Vertin NR, Yang H, Johnson MD, Bailey RC. Rapid, Multiplexed Phosphoprotein Profiling Using Silicon Photonic Sensor Arrays. ACS Cent Sci. 2015 Oct 28; 1(7):374-382. PMID: 26539563.
      Citations:    
    5. Kim J, Lee IH, Cho HJ, Park CK, Jung YS, Kim Y, Nam SH, Kim BS, Johnson MD, Kong DS, Seol HJ, Lee JI, Joo KM, Yoon Y, Park WY, Lee J, Park PJ, Nam DH. Spatiotemporal Evolution of the Primary Glioblastoma Genome. Cancer Cell. 2015 Sep 14; 28(3):318-28. PMID: 26373279.
      Citations: 170     Fields:    Translation:Humans
    6. Hulou MM, Cote DJ, Olubiyi OI, Smith TR, Chiocca EA, Johnson MD. Awake right hemisphere brain surgery. J Clin Neurosci. 2015 Dec; 22(12):1921-7. PMID: 26279501.
      Citations: 3     Fields:    Translation:Humans
    7. Liu Y, Alexander BM, Chen YH, Horvath MC, Aizer AA, Claus EB, Dunn IF, Golby AJ, Johnson MD, Friesen S, Mannarino EG, Wagar M, Hacker FL, Arvold ND. Salvage whole brain radiotherapy or stereotactic radiosurgery after initial stereotactic radiosurgery for 1-4 brain metastases. J Neurooncol. 2015 Sep; 124(3):429-37. PMID: 26108659.
      Citations: 9     Fields:    Translation:Humans
    8. Rahman R, Catalano PJ, Reardon DA, Norden AD, Wen PY, Lee EQ, Nayak L, Beroukhim R, Dunn IF, Golby AJ, Johnson MD, Chiocca EA, Claus EB, Alexander BM, Arvold ND. Incidence, risk factors, and reasons for hospitalization among glioblastoma patients receiving chemoradiation. J Neurooncol. 2015 Aug; 124(1):137-46. PMID: 26033544.
      Citations: 4     Fields:    Translation:Humans
    9. Ansari KI, Ogawa D, Rooj AK, Lawler SE, Krichevsky AM, Johnson MD, Chiocca EA, Bronisz A, Godlewski J. Glucose-based regulation of miR-451/AMPK signaling depends on the OCT1 transcription factor. Cell Rep. 2015 May 12; 11(6):902-909. PMID: 25937278.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    10. Arvold ND, Tanguturi SK, Aizer AA, Wen PY, Reardon DA, Lee EQ, Nayak L, Christianson LW, Horvath MC, Dunn IF, Golby AJ, Johnson MD, Claus EB, Chiocca EA, Ligon KL, Alexander BM. Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients. Int J Radiat Oncol Biol Phys. 2015 Jun 01; 92(2):384-9. PMID: 25841623.
      Citations: 22     Fields:    Translation:Humans
    11. Ramkissoon SH, Bi WL, Schumacher SE, Ramkissoon LA, Haidar S, Knoff D, Dubuc A, Brown L, Burns M, Cryan JB, Abedalthagafi M, Kang YJ, Schultz N, Reardon DA, Lee EQ, Rinne ML, Norden AD, Nayak L, Ruland S, Doherty LM, LaFrankie DC, Horvath M, Aizer AA, Russo A, Arvold ND, Claus EB, Al-Mefty O, Johnson MD, Golby AJ, Dunn IF, Chiocca EA, Trippa L, Santagata S, Folkerth RD, Kantoff P, Rollins BJ, Lindeman NI, Wen PY, Ligon AH, Beroukhim R, Alexander BM, Ligon KL. Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma. Neuro Oncol. 2015 Oct; 17(10):1344-55. PMID: 25754088.
      Citations: 26     Fields:    Translation:Humans
    12. Yang HW, Xing H, Johnson MD. A major role for microRNAs in glioblastoma cancer stem-like cells. Arch Pharm Res. 2015 Mar; 38(3):423-34. PMID: 25683176.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    13. Yang HW, Kim TM, Song SS, Menon L, Jiang X, Huang W, Black PM, Park PJ, Carroll RS, Johnson MD. A small subunit processome protein promotes cancer by altering translation. Oncogene. 2015 Aug 20; 34(34):4471-81. PMID: 25435373.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    14. Godlewski J, Krichevsky AM, Johnson MD, Chiocca EA, Bronisz A. Belonging to a network--microRNAs, extracellular vesicles, and the glioblastoma microenvironment. Neuro Oncol. 2015 May; 17(5):652-62. PMID: 25301812.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    15. Rajakesari S, Arvold ND, Jimenez RB, Christianson LW, Horvath MC, Claus EB, Golby AJ, Johnson MD, Dunn IF, Lee EQ, Lin NU, Friesen S, Mannarino EG, Wagar M, Hacker FL, Weiss SE, Alexander BM. Local control after fractionated stereotactic radiation therapy for brain metastases. J Neurooncol. 2014 Nov; 120(2):339-46. PMID: 25059451.
      Citations: 23     Fields:    Translation:Humans
    16. Aizer AA, Arvold ND, Catalano P, Claus EB, Golby AJ, Johnson MD, Al-Mefty O, Wen PY, Reardon DA, Lee EQ, Nayak L, Rinne ML, Beroukhim R, Weiss SE, Ramkissoon SH, Abedalthagafi M, Santagata S, Dunn IF, Alexander BM. Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma. Neuro Oncol. 2014 Nov; 16(11):1547-53. PMID: 24891451.
      Citations: 29     Fields:    Translation:Humans
    17. Li H, Jiang X, Yu Y, Huang W, Xing H, Agar NY, Yang HW, Yang B, Carroll RS, Johnson MD. KAP regulates ROCK2 and Cdk2 in an RNA-activated glioblastoma invasion pathway. Oncogene. 2015 Mar 12; 34(11):1432-41. PMID: 24704824.
      Citations: 17     Fields:    Translation:HumansCells
    18. Kim TM, Xi R, Luquette LJ, Park RW, Johnson MD, Park PJ. Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes. Genome Res. 2013 Feb; 23(2):217-27. PMID: 23132910.
      Citations: 75     Fields:    Translation:Humans
    19. Jiang X, Xing H, Kim TM, Jung Y, Huang W, Yang HW, Song S, Park PJ, Carroll RS, Johnson MD. Numb regulates glioma stem cell fate and growth by altering epidermal growth factor receptor and Skp1-Cullin-F-box ubiquitin ligase activity. Stem Cells. 2012 Jul; 30(7):1313-26. PMID: 22553175.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    20. Yang HW, Kim TM, Song SS, Shrinath N, Park R, Kalamarides M, Park PJ, Black PM, Carroll RS, Johnson MD. Alternative splicing of CHEK2 and codeletion with NF2 promote chromosomal instability in meningioma. Neoplasia. 2012 Jan; 14(1):20-8. PMID: 22355270.
      Citations: 22     Fields:    Translation:HumansCells
    21. Xi R, Hadjipanayis AG, Luquette LJ, Kim TM, Lee E, Zhang J, Johnson MD, Muzny DM, Wheeler DA, Gibbs RA, Kucherlapati R, Park PJ. Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):E1128-36. PMID: 22065754.
      Citations: 124     Fields:    Translation:Humans
    22. Lin N, Dunn IF, Glantz M, Allison DL, Jensen R, Johnson MD, Friedlander RM, Kesari S. Benefit of ventriculoperitoneal cerebrospinal fluid shunting and intrathecal chemotherapy in neoplastic meningitis: a retrospective, case-controlled study. J Neurosurg. 2011 Oct; 115(4):730-6. PMID: 21721878.
      Citations: 23     Fields:    Translation:Humans
    23. Kim TM, Huang W, Park R, Park PJ, Johnson MD. A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs. Cancer Res. 2011 May 01; 71(9):3387-99. PMID: 21385897.
      Citations: 113     Fields:    Translation:HumansCells
    24. Yang HW, Menon LG, Black PM, Carroll RS, Johnson MD. SNAI2/Slug promotes growth and invasion in human gliomas. BMC Cancer. 2010 Jun 17; 10:301. PMID: 20565806.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    25. Agar NY, Malcolm JG, Mohan V, Yang HW, Johnson MD, Tannenbaum A, Agar JN, Black PM. Imaging of meningioma progression by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Anal Chem. 2010 Apr 01; 82(7):2621-5. PMID: 20196536.
      Citations: 15     Fields:    Translation:Humans
    26. Kim H, Huang W, Jiang X, Pennicooke B, Park PJ, Johnson MD. Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship. Proc Natl Acad Sci U S A. 2010 Feb 02; 107(5):2183-8. PMID: 20080666.
      Citations: 120     Fields:    Translation:HumansAnimalsCells
    27. Jiang X, Yu Y, Yang HW, Agar NY, Frado L, Johnson MD. The imprinted gene PEG3 inhibits Wnt signaling and regulates glioma growth. J Biol Chem. 2010 Mar 12; 285(11):8472-80. PMID: 20064927.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    28. Dreyfuss JM, Johnson MD, Park PJ. Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers. Mol Cancer. 2009 Sep 04; 8:71. PMID: 19732454.
      Citations: 29     Fields:    Translation:Humans
    29. Yu Y, Jiang X, Schoch BS, Carroll RS, Black PM, Johnson MD. Aberrant splicing of cyclin-dependent kinase-associated protein phosphatase KAP increases proliferation and migration in glioblastoma. Cancer Res. 2007 Jan 01; 67(1):130-8. PMID: 17210692.
      Citations: 41     Fields:    Translation:HumansCells
    30. Liu F, Park PJ, Lai W, Maher E, Chakravarti A, Durso L, Jiang X, Yu Y, Brosius A, Thomas M, Chin L, Brennan C, DePinho RA, Kohane I, Carroll RS, Black PM, Johnson MD. A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma. Cancer Res. 2006 Nov 15; 66(22):10815-23. PMID: 17090523.
      Citations: 58     Fields:    Translation:HumansCells
    31. Lai WR, Johnson MD, Kucherlapati R, Park PJ. Comparative analysis of algorithms for identifying amplifications and deletions in array CGH data. Bioinformatics. 2005 Oct 01; 21(19):3763-70. PMID: 16081473.
      Citations: 162     Fields:    Translation:Cells
    32. Johnson MD, Yu LR, Conrads TP, Kinoshita Y, Uo T, McBee JK, Veenstra TD, Morrison RS. The proteomics of neurodegeneration. Am J Pharmacogenomics. 2005; 5(4):259-70. PMID: 16078862.
      Citations: 7     Fields:    Translation:HumansAnimals
    33. Black PM, Johnson MD. Surgical resection for patients with solid brain metastases: current status. J Neurooncol. 2004 Aug-Sep; 69(1-3):119-24. PMID: 15527084.
      Citations: 10     Fields:    Translation:Humans
    34. Johnson MD, Burchiel KJ. Peripheral stimulation for treatment of trigeminal postherpetic neuralgia and trigeminal posttraumatic neuropathic pain: a pilot study. Neurosurgery. 2004 Jul; 55(1):135-41; discussion 141-2. PMID: 15214982.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    35. Johnson MD, Yu LR, Conrads TP, Kinoshita Y, Uo T, Matthews JD, Lee SW, Smith RD, Veenstra TD, Morrison RS. Proteome analysis of DNA damage-induced neuronal death using high throughput mass spectrometry. J Biol Chem. 2004 Jun 18; 279(25):26685-97. PMID: 15060066.
      Citations: 11     Fields:    Translation:AnimalsCells
    36. Morrison RS, Kinoshita Y, Johnson MD, Conrads TP. Proteomics in the postgenomic age. Adv Protein Chem. 2003; 65:1-23. PMID: 12964364.
      Citations: 1     Fields:    Translation:HumansAnimals
    37. Morrison RS, Kinoshita Y, Johnson MD, Guo W, Garden GA. p53-dependent cell death signaling in neurons. Neurochem Res. 2003 Jan; 28(1):15-27. PMID: 12587660.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    38. Morrison RS, Kinoshita Y, Johnson MD, Uo T, Ho JT, McBee JK, Conrads TP, Veenstra TD. Proteomic analysis in the neurosciences. Mol Cell Proteomics. 2002 Aug; 1(8):553-60. PMID: 12376570.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    39. Johnson MD, Wu X, Aithmitti N, Morrison RS. Peg3/Pw1 is a mediator between p53 and Bax in DNA damage-induced neuronal death. J Biol Chem. 2002 Jun 21; 277(25):23000-7. PMID: 11943780.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    40. Morrison RS, Kinoshita Y, Johnson MD, Ghatan S, Ho JT, Garden G. Neuronal survival and cell death signaling pathways. Adv Exp Med Biol. 2002; 513:41-86. PMID: 12575817.
      Citations: 20     Fields:    Translation:Cells
    41. Johnson MD, Ojemann GA. The role of the human thalamus in language and memory: evidence from electrophysiological studies. Brain Cogn. 2000 Mar; 42(2):218-30. PMID: 10744921.
      Citations: 55     Fields:    Translation:Humans
    42. Johnson MD, Kinoshita Y, Xiang H, Ghatan S, Morrison RS. Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation. J Neurosci. 1999 Apr 15; 19(8):2996-3006. PMID: 10191317.
      Citations: 25     Fields:    Translation:AnimalsCells
    43. Johnson MD, Xiang H, London S, Kinoshita Y, Knudson M, Mayberg M, Korsmeyer SJ, Morrison RS. Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons. J Neurosci Res. 1998 Dec 15; 54(6):721-33. PMID: 9856857.
      Citations: 28     Fields:    Translation:AnimalsCells
    44. Johnson MD, Yee AG. Ultrastructure of electrophysiologically-characterized synapses formed by serotonergic raphe neurons in culture. Neuroscience. 1995 Aug; 67(3):609-23. PMID: 7675190.
      Citations: 9     Fields:    Translation:AnimalsCells
    45. Johnson MD. Electrophysiological and histochemical properties of postnatal rat serotonergic neurons in dissociated cell culture. Neuroscience. 1994 Dec; 63(3):775-87. PMID: 7898677.
      Citations: 7     Fields:    Translation:AnimalsCells
    46. Johnson MD. Synaptic glutamate release by postnatal rat serotonergic neurons in microculture. Neuron. 1994 Feb; 12(2):433-42. PMID: 7906530.
      Citations: 42     Fields:    Translation:AnimalsCells
    47. Johnson MD, Ma PM. Localization of NADPH diaphorase activity in monoaminergic neurons of the rat brain. J Comp Neurol. 1993 Jun 22; 332(4):391-406. PMID: 8102384.
      Citations: 14     Fields:    Translation:AnimalsCells
    48. Simpkins CO, Mazorow DL, Alailima ST, Tate EA, Sweatt W, Johnson M, Shariff K, Millar DB. Prostaglandin D2 modulates human neutrophil intracellular calcium flux and inhibits superoxide release via its ring carbonyl. Life Sci. 1990; 46(11):793-801. PMID: 2319907.
      Citations:    Fields:    Translation:HumansCells
    49. Johnson MD, Potter DD. Co-culture of dissociated hippocampal and sympathetic cells from the neonatal rat. Q J Exp Physiol. 1989 Dec; 74(7):1043-50. PMID: 2626532.
      Citations:    Fields:    Translation:AnimalsCells
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