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Erica Ollmann Saphire PhD

TitleAdjunct Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMicrobiology and Physiological Systems
AddressLa Jolla Institute for Immunology
94230 Athena Circle
La Jolla CA 92037
Phone858-784-8602
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMicrobiology and Physiological Systems


    Collapse Biography 
    Collapse education and training
    Rice University, Houston, TX, United StatesBABiochemistry/Cell Biology
    Scripps Research Institute, La Jolla, CA, United StatesPHDMolecular Biology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. King LB, Milligan JC, West BR, Schendel SL, Ollmann Saphire E. Achieving cross-reactivity with pan-ebolavirus antibodies. Curr Opin Virol. 2019 Mar 15; 34:140-148. PMID: 30884329.
      View in: PubMed
    2. Saphire EO, Schendel SL, Gunn BM, Milligan JC, Alter G. Antibody-mediated protection against Ebola virus. Nat Immunol. 2018 Nov; 19(11):1169-1178. PMID: 30333617.
      View in: PubMed
    3. Bramble MS, Hoff N, Gilchuk P, Mukadi P, Lu K, Doshi RH, Steffen I, Nicholson BP, Lipson A, Vashist N, Sinai C, Spencer D, Olinger G, Wemakoy EO, Illunga BK, Pettitt J, Logue J, Marchand J, Varughese J, Bennett RS, Jahrling P, Cavet G, Serafini T, Ollmann Saphire E, Vilain E, Muyembe-Tamfum JJ, Hensely LE, Simmons G, Crowe JE, Rimoin AW. Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors. J Infect Dis. 2018 Aug 13. PMID: 30107445.
      View in: PubMed
    4. Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 2018 Aug 09; 174(4):938-952.e13. PMID: 30096313.
      View in: PubMed
    5. Amanat F, Duehr J, Oestereich L, Hastie KM, Ollmann Saphire E, Krammer F. Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses. mSphere. 2018 May-Jun; 3(3). PMID: 29720525.
      View in: PubMed
    6. Galan-Navarro C, Rincon-Restrepo M, Zimmer G, Ollmann Saphire E, Hubbell JA, Hirosue S, Swartz MA, Kunz S. Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein. Virology. 2017 12; 512:161-171. PMID: 28963882.
      View in: PubMed
    7. Wasserman H, Saphire EO. More than Meets the Eye: Hidden Structures in the Proteome. Annu Rev Virol. 2016 09 29; 3(1):373-386. PMID: 27482901.
      View in: PubMed
    8. Saphire EO, Aman MJ. Feverish Quest for Ebola Immunotherapy: Straight or Cocktail? Trends Microbiol. 2016 09; 24(9):684-686. PMID: 27338027.
      View in: PubMed
    9. Burton DR, Saphire EO. Swift antibodies to counter emerging viruses. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10082-3. PMID: 26261336; PMCID: PMC4547222.
    10. Saphire EO. New Advances in the Effort against Ebola. Cell Host Microbe. 2015 May 13; 17(5):545-7. PMID: 25974296.
      View in: PubMed
    11. Saphire EO. An update on the use of antibodies against the filoviruses. Immunotherapy. 2013 Nov; 5(11):1221-33. PMID: 24188676; PMCID: PMC4465755.
    12. Stanfield RL, Ghiara JB, Ollmann Saphire E, Profy AT, Wilson IA. Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop. Virology. 2003 Oct 10; 315(1):159-73. PMID: 14592768.
      View in: PubMed
    13. Pantophlet R, Ollmann Saphire E, Poignard P, Parren PW, Wilson IA, Burton DR. Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120. J Virol. 2003 Jan; 77(1):642-58. PMID: 12477867; PMCID: PMC140633.
    14. Scanlan CN, Pantophlet R, Wormald MR, Ollmann Saphire E, Stanfield R, Wilson IA, Katinger H, Dwek RA, Rudd PM, Burton DR. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120. J Virol. 2002 Jul; 76(14):7306-21. PMID: 12072529; PMCID: PMC136327.
    15. Saphire EO. Structure-based drug design. IDrugs. 2002 Jul; 5(7):658-61. PMID: 14686344.
      View in: PubMed
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