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Scott A. Loiler PHD

TitleAdjunct Assistant Professor
InstitutionUniversity of Massachusetts Medical School
DepartmentMicrobiology and Physiological Systems
AddressResearch Institute at Nationwide Children's Hospital
700 Children's Dr, WA3012
Columbus OH 43205
Phone614-722-2739
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    Other Positions
    InstitutionUMMS - School of Medicine
    DepartmentMicrobiology and Physiological Systems


    Collapse Biography 
    Collapse education and training
    Rutgers University, New Brunswick, NJ, United StatesBA
    University of Massachusetts Medical School, Worcester, MA, United StatesPHD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Aalbers CJ, Bevaart L, Loiler S, de Cortie K, Wright JF, Mingozzi F, Tak PP, Vervoordeldonk MJ. Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-ß (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis. PLoS One. 2015; 10(6):e0130612. PMID: 26107769; PMCID: PMC4479517.
    2. Ngo D, Beaulieu E, Gu R, Leaney A, Santos L, Fan H, Yang Y, Kao W, Xu J, Escriou V, Loiler S, Vervoordeldonk MJ, Morand EF. Divergent effects of endogenous and exogenous glucocorticoid-induced leucine zipper in animal models of inflammation and arthritis. Arthritis Rheum. 2013 May; 65(5):1203-12. PMID: 23335223.
      View in: PubMed
    3. Liqun Wang R, McLaughlin T, Cossette T, Tang Q, Foust K, Campbell-Thompson M, Martino A, Cruz P, Loiler S, Mueller C, Flotte TR. Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery. Mol Ther. 2009 Jan; 17(1):81-7. PMID: 18941444.
      View in: PubMed
    4. Pasarica M, Loiler S, Dhurandhar NV. Acute effect of infection by adipogenic human adenovirus Ad36. Arch Virol. 2008; 153(11):2097-102. PMID: 18830560; PMCID: PMC2744363.
    5. Rogers PM, Fusinski KA, Rathod MA, Loiler SA, Pasarica M, Shaw MK, Kilroy G, Sutton GM, McAllister EJ, Mashtalir N, Gimble JM, Holland TC, Dhurandhar NV. Human adenovirus Ad-36 induces adipogenesis via its E4 orf-1 gene. Int J Obes (Lond). 2008 Mar; 32(3):397-406. PMID: 17984979.
      View in: PubMed
    6. Loiler SA, Tang Q, Clarke T, Campbell-Thompson ML, Chiodo V, Hauswirth W, Cruz P, Perret-Gentil M, Atkinson MA, Ramiya VK, Flotte TR. Localized gene expression following administration of adeno-associated viral vectors via pancreatic ducts. Mol Ther. 2005 Sep; 12(3):519-27. PMID: 15979413.
      View in: PubMed
    7. Virella-Lowell I, Zusman B, Foust K, Loiler S, Conlon T, Song S, Chesnut KA, Ferkol T, Flotte TR. Enhancing rAAV vector expression in the lung. J Gene Med. 2005 Jul; 7(7):842-50. PMID: 15838934.
      View in: PubMed
    8. Chen S, Kapturczak M, Loiler SA, Zolotukhin S, Glushakova OY, Madsen KM, Samulski RJ, Hauswirth WW, Campbell-Thompson M, Berns KI, Flotte TR, Atkinson MA, Tisher CC, Agarwal A. Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors. Hum Gene Ther. 2005 Feb; 16(2):235-47. PMID: 15761263.
      View in: PubMed
    9. Mohiuddin I, Loiler S, Zolotukhin I, Byrne BJ, Flotte TR, Snyder RO. Herpesvirus-based infectious titering of recombinant adeno-associated viral vectors. Mol Ther. 2005 Feb; 11(2):320-6. PMID: 15668144.
      View in: PubMed
    10. Burkhardt BR, Loiler SA, Anderson JA, Kilberg MS, Crawford JM, Flotte TR, Goudy KS, Ellis TM, Atkinson M. Glucose-responsive expression of the human insulin promoter in HepG2 human hepatoma cells. Ann N Y Acad Sci. 2003 Nov; 1005:237-41. PMID: 14679068.
      View in: PubMed
    11. Loiler SA, Conlon TJ, Song S, Tang Q, Warrington KH, Agarwal A, Kapturczak M, Li C, Ricordi C, Atkinson MA, Muzyczka N, Flotte TR. Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver. Gene Ther. 2003 Sep; 10(18):1551-8. PMID: 12907946.
      View in: PubMed
    12. DiFronzo NL, Frieder M, Loiler SA, Pham QN, Holland CA. Duplication of U3 sequences in the long terminal repeat of mink cell focus-inducing viruses generates redundancies of transcription factor binding sites important for the induction of thymomas. J Virol. 2003 Mar; 77(5):3326-33. PMID: 12584358; PMCID: PMC149780.
    13. Zolotukhin S, Potter M, Zolotukhin I, Sakai Y, Loiler S, Fraites TJ, Chiodo VA, Phillipsberg T, Muzyczka N, Hauswirth WW, Flotte TR, Byrne BJ, Snyder RO. Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods. 2002 Oct; 28(2):158-67. PMID: 12413414.
      View in: PubMed
    14. Flotte T, Agarwal A, Wang J, Song S, Fenjves ES, Inverardi L, Chesnut K, Afione S, Loiler S, Wasserfall C, Kapturczak M, Ellis T, Nick H, Atkinson M. Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors. Diabetes. 2001 Mar; 50(3):515-20. PMID: 11246870.
      View in: PubMed
    15. Hernandez YJ, Wang J, Kearns WG, Loiler S, Poirier A, Flotte TR. Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model. J Virol. 1999 Oct; 73(10):8549-58. PMID: 10482608.
      View in: PubMed
    16. Loiler SA, DiFronzo NL, Holland CA. Gene transfer to human cells using retrovirus vectors produced by a new polytropic packaging cell line. J Virol. 1997 Jun; 71(6):4825-8. PMID: 9151879; PMCID: PMC191707.
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