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Fiachra Emanuel Humphries PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentMedicine
AddressUMass Chan Medical School
364 Plantation Street
Worcester MA 01605
Phone508-365-4582
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentBiochemistry and Molecular Biotechnology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentCancer Biology

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentImmunology and Microbiology Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentInterdisciplinary Graduate Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentMD/PhD Program

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentNeuroscience


    Collapse Biography 
    Collapse education and training
    National University of Ireland, Maynooth, KLDARE, IrelandBSBiotechnology
    National University of Ireland, Maynooth, KLDARE, IrelandPHDImmunology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Humphries F, Fitzgerald KA. Igniting the firestorm: The inflammasome in autoinflammatory syndromes. J Allergy Clin Immunol. 2021 12; 148(6):1470-1472. PMID: 34403657.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Shmuel-Galia L, Humphries F, Lei X, Ceglia S, Wilson R, Jiang Z, Ketelut-Carneiro N, Foley SE, Pechhold S, Houghton J, Muneeruddin K, Shaffer SA, McCormick BA, Reboldi A, Ward D, Marshak-Rothstein A, Fitzgerald KA. Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells. Immunity. 2021 06 08; 54(6):1137-1153.e8. PMID: 34051146.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    3. Humphries F, Fitzgerald KA. Loosening the grip on nuclear cGAS. Nat Genet. 2020 12; 52(12):1269-1270. PMID: 33230301.
      Citations:    Fields:    Translation:Cells
    4. Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, Thompson PR, Fitzgerald KA. Succination inactivates gasdermin D and blocks pyroptosis. Science. 2020 09 25; 369(6511):1633-1637. PMID: 32820063.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    5. Humphries F, Fitzgerald KA. hnRNPA2B1: Fueling Antiviral Immunity from the Nucleus. Mol Cell. 2019 10 03; 76(1):8-10. PMID: 31585104.
      Citations:    Fields:    Translation:Cells
    6. Humphries F, Fitzgerald KA. Assembling the Inflammasome, Piece by Piece. J Immunol. 2019 09 01; 203(5):1093-1094. PMID: 31427397.
      Citations: 1     Fields:    Translation:Humans
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