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Ashley R Brown PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
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    Other Positions
    InstitutionT.H. Chan School of Medicine

    Collapse Biography 
    Collapse education and training
    Boston University, Boston, MA, United StatesBAPsychology
    University of North Carolina, Greensboro, Greensboro, NC, United StatesMAPsychology
    University of North Carolina, Greensboro, Greensboro, NC, United StatesPHD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lawler AJ, Ramamurthy E, Brown AR, Shin N, Kim Y, Toong N, Kaplow IM, Wirthlin M, Zhang X, Phan BN, Fox GA, Wade K, He J, Ozturk BE, Byrne LC, Stauffer WR, Fish KN, Pfenning AR. Machine learning sequence prioritization for cell type-specific enhancer design. Elife. 2022 May 16; 11. PMID: 35576146.
      Citations:    Fields:    Translation:AnimalsCells
    2. Kaplow IM, Schäffer DE, Wirthlin ME, Lawler AJ, Brown AR, Kleyman M, Pfenning AR. Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin. BMC Genomics. 2022 Apr 11; 23(1):291. PMID: 35410163.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Brown AR, Wodzanowski KA, Santiago CC, Hyland SN, Follmar JL, Asare-Okai P, Grimes CL. Protected N-Acetyl Muramic Acid Probes Improve Bacterial Peptidoglycan Incorporation via Metabolic Labeling. ACS Chem Biol. 2021 10 15; 16(10):1908-1916. PMID: 34506714.
      Citations: 2     Fields:    Translation:Cells
    4. Srinivasan C, Phan BN, Lawler AJ, Ramamurthy E, Kleyman M, Brown AR, Kaplow IM, Wirthlin ME, Pfenning AR. Addiction-Associated Genetic Variants Implicate Brain Cell Type- and Region-Specific Cis-Regulatory Elements in Addiction Neurobiology. J Neurosci. 2021 10 27; 41(43):9008-9030. PMID: 34462306.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    5. Lawler AJ, Brown AR, Bouchard RS, Toong N, Kim Y, Velraj N, Fox G, Kleyman M, Kang B, Gittis AH, Pfenning AR. Cell Type-Specific Oxidative Stress Genomic Signatures in the Globus Pallidus of Dopamine-Depleted Mice. J Neurosci. 2020 12 09; 40(50):9772-9783. PMID: 33188066.
      Citations: 3     Fields:    Translation:AnimalsCells
    6. Brown AR, Gordon RA, Hyland SN, Siegrist MS, Grimes CL. Chemical Biology Tools for Examining the Bacterial Cell Wall. Cell Chem Biol. 2020 08 20; 27(8):1052-1062. PMID: 32822617.
      Citations: 4     Fields:    Translation:Cells
    7. Ukaegbu OI, DeMeester KE, Liang H, Brown AR, Jones ZS, Grimes CL. Utility of bacterial peptidoglycan recycling enzymes in the chemoenzymatic synthesis of valuable UDP sugar substrates. Methods Enzymol. 2020; 638:1-26. PMID: 32416908.
      Citations:    Fields:    Translation:Cells
    8. Aeppli M, Vranic S, Kaegi R, Kretzschmar R, Brown AR, Voegelin A, Hofstetter TB, Sander M. Decreases in Iron Oxide Reducibility during Microbial Reductive Dissolution and Transformation of Ferrihydrite. Environ Sci Technol. 2019 Aug 06; 53(15):8736-8746. PMID: 31339302.
      Citations: 2     Fields:    Translation:Cells
    9. D'Ambrosio EA, Drake WR, Mashayekh S, Ukaegbu OI, Brown AR, Grimes CL. Modulation of the NOD-like receptors NOD1 and NOD2: A chemist's perspective. Bioorg Med Chem Lett. 2019 05 15; 29(10):1153-1161. PMID: 30890292.
      Citations: 4     Fields:    Translation:HumansCells
    10. MeGraw VE, Brown AR, Boothman C, Goodacre R, Morris K, Sigee D, Anderson L, Lloyd JR. A Novel Adaptation Mechanism Underpinning Algal Colonization of a Nuclear Fuel Storage Pond. mBio. 2018 06 26; 9(3). PMID: 29946053.
      Citations: 6     Fields:    Translation:AnimalsCells
    11. Simonelli V, Leuzzi G, Basile G, D'Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E. Crosstalk between mismatch repair and base excision repair in human gastric cancer. Oncotarget. 2017 Oct 17; 8(49):84827-84840. PMID: 29156686.
      Citations: 9     Fields:    
    12. Brown AR, Correa E, Xu Y, AlMasoud N, Pimblott SM, Goodacre R, Lloyd JR. Phenotypic Characterisation of Shewanella oneidensis MR-1 Exposed to X-Radiation. PLoS One. 2015; 10(6):e0131249. PMID: 26098880.
      Citations: 1     Fields:    Translation:Cells
    13. Brown AR, Boothman C, Pimblott SM, Lloyd JR. The impact of gamma radiation on sediment microbial processes. Appl Environ Microbiol. 2015 Jun 15; 81(12):4014-25. PMID: 25841009.
      Citations: 2     Fields:    Translation:CellsPHPublic Health
    14. Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase ?. Nat Commun. 2014 Nov 26; 5:5513. PMID: 25423885.
      Citations: 50     Fields:    Translation:HumansCells
    15. Brown AR, Wincott PL, LaVerne JA, Small JS, Vaughan DJ, Pimblott SM, Lloyd JR. The impact of ? radiation on the bioavailability of Fe(III) minerals for microbial respiration. Environ Sci Technol. 2014 Sep 16; 48(18):10672-80. PMID: 25195952.
      Citations: 4     Fields:    Translation:CellsPHPublic Health
    16. Nagaria P, Svilar D, Brown AR, Wang XH, Sobol RW, Wyatt MD. SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress. Mutat Res. 2013 Mar-Apr; 743-744:26-32. PMID: 23253900.
      Citations: 9     Fields:    Translation:HumansCells
    17. Svilar D, Dyavaiah M, Brown AR, Tang JB, Li J, McDonald PR, Shun TY, Braganza A, Wang XH, Maniar S, St Croix CM, Lazo JS, Pollack IF, Begley TJ, Sobol RW. Alkylation sensitivity screens reveal a conserved cross-species functionome. Mol Cancer Res. 2012 Dec; 10(12):1580-96. PMID: 23038810.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    18. Thurman RJ, Brown AR, Ferre RM. Progressive foot swelling and pain. Posttraumatic dorsalis pedis pseudoaneurysm. Ann Emerg Med. 2012 Jun; 59(6):556, 560. PMID: 22626020.
      Citations: 1     Fields:    Translation:Humans
    19. Goellner EM, Grimme B, Brown AR, Lin YC, Wang XH, Sugrue KF, Mitchell L, Trivedi RN, Tang JB, Sobol RW. Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. Cancer Res. 2011 Mar 15; 71(6):2308-17. PMID: 21406402.
      Citations: 67     Fields:    Translation:HumansCells
    20. Tang JB, Svilar D, Trivedi RN, Wang XH, Goellner EM, Moore B, Hamilton RL, Banze LA, Brown AR, Sobol RW. N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. Neuro Oncol. 2011 May; 13(5):471-86. PMID: 21377995.
      Citations: 57     Fields:    Translation:HumansCells
    21. Kothandapani A, Dangeti VS, Brown AR, Banze LA, Wang XH, Sobol RW, Patrick SM. Novel role of base excision repair in mediating cisplatin cytotoxicity. J Biol Chem. 2011 Apr 22; 286(16):14564-74. PMID: 21357694.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    22. Lisovich A, Chandran UR, Lyons-Weiler MA, LaFramboise WA, Brown AR, Jakacki RI, Pollack IF, Sobol RW. A novel SNP analysis method to detect copy number alterations with an unbiased reference signal directly from tumor samples. BMC Med Genomics. 2011 Jan 26; 4:14. PMID: 21269491.
      Citations: 3     Fields:    Translation:Humans
    23. Jelezcova E, Trivedi RN, Wang XH, Tang JB, Brown AR, Goellner EM, Schamus S, Fornsaglio JL, Sobol RW. Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. Mutat Res. 2010 Apr 01; 686(1-2):57-67. PMID: 20096707.
      Citations: 18     Fields:    Translation:AnimalsCells
    24. Tang JB, Goellner EM, Wang XH, Trivedi RN, St Croix CM, Jelezcova E, Svilar D, Brown AR, Sobol RW. Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage. Mol Cancer Res. 2010 Jan; 8(1):67-79. PMID: 20068071.
      Citations: 42     Fields:    Translation:HumansCells
    25. Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH. DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst). 2010 Feb 04; 9(2):109-19. PMID: 20006562.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    26. Taioli E, Ragin C, Wang XH, Chen J, Langevin SM, Brown AR, Gollin SM, Garte S, Sobol RW. Recurrence in oral and pharyngeal cancer is associated with quantitative MGMT promoter methylation. BMC Cancer. 2009 Oct 06; 9:354. PMID: 19807915.
      Citations: 25     Fields:    Translation:HumansCells
    27. Yoshizawa K, Jelezcova E, Brown AR, Foley JF, Nyska A, Cui X, Hofseth LJ, Maronpot RM, Wilson SH, Sepulveda AR, Sobol RW. Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. PLoS One. 2009 Aug 05; 4(8):e6493. PMID: 19654874.
      Citations: 11     Fields:    Translation:AnimalsCells
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