Header Logo

Darren James Lee PhD

TitleAssociate Professor
InstitutionUMass Chan Medical School
DepartmentOphthalmology and Visual Sciences
AddressUMass Chan Medical School
55 Lake Avenue North
Worcester MA 01655
vCardDownload vCard
    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentNeuroNexus Institute

    InstitutionT.H. Chan School of Medicine
    DepartmentOphthalmology and Visual Sciences

    InstitutionMorningside Graduate School of Biomedical Sciences
    DepartmentImmunology and Microbiology Program

    InstitutionMorningside Graduate School of Biomedical Sciences

    Collapse Biography 
    Collapse education and training
    University of California, Davis, Davis, CA, United StatesBS
    University of New Hampshire Durham, Durham, NH, United StatesPHD

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Teabagy S, Wood E, Bilsbury E, Doherty S, Janardhana P, Lee DJ. Ocular immunosuppressive microenvironment and novel drug delivery for control of uveitis. Adv Drug Deliv Rev. 2023 07; 198:114869. PMID: 37172782.
      Citations:    Fields:    Translation:Humans
    2. Peters K, McDonald T, Muhammad F, Walsh M, Drenen K, Montieth A, Stephen Foster C, Lee DJ. A2Ar-dependent PD-1+ and TIGIT+ Treg cells have distinct homing requirements to suppress autoimmune uveitis in mice. Mucosal Immunol. 2023 08; 16(4):422-431. PMID: 37164238.
      Citations: 1     Fields:    Translation:AnimalsCells
    3. McDonald T, Muhammad F, Peters K, Lee DJ. Combined Deficiency of the Melanocortin 5 Receptor and Adenosine 2A Receptor Unexpectedly Provides Resistance to Autoimmune Disease in a CD8+ T Cell-Dependent Manner. Front Immunol. 2021; 12:742154. PMID: 34867964.
      Citations: 2     Fields:    Translation:AnimalsCells
    4. Lee DJ, Xu H, Taylor AW. Editorial: Retinal Immunobiology and Retinopathy. Front Immunol. 2021; 12:758375. PMID: 34539681.
      Citations: 1     Fields:    Translation:HumansCells
    5. Muhammad F, Avalos PN, Mursalin MH, Ma JX, Callegan MC, Lee DJ. Kallistatin Attenuates Experimental Autoimmune Uveitis by Inhibiting Activation of T Cells. Front Immunol. 2020; 11:975. PMID: 32508841.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Muhammad F, Wang D, McDonald T, Walsh M, Drenen K, Montieth A, Foster CS, Lee DJ. TIGIT+ A2Ar-Dependent anti-uveitic Treg cells are a novel subset of Tregs associated with resolution of autoimmune uveitis. J Autoimmun. 2020 07; 111:102441. PMID: 32201225.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    7. Lee DJ. The relationship between TIGIT+ regulatory T cells and autoimmune disease. Int Immunopharmacol. 2020 Jun; 83:106378. PMID: 32172208.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    8. Muhammad F, Wang D, Montieth A, Lee S, Preble J, Foster CS, Larson TA, Ding K, Dvorak JD, Lee DJ. PD-1+ melanocortin receptor dependent-Treg cells prevent autoimmune disease. Sci Rep. 2019 11 15; 9(1):16941. PMID: 31729418.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    9. Muhammad FY, Peters K, Wang D, Lee DJ. Exacerbation of autoimmune uveitis by obesity occurs through the melanocortin 5 receptor. J Leukoc Biol. 2019 10; 106(4):879-887. PMID: 31287586.
      Citations: 7     Fields:    Translation:AnimalsCells
    10. Muhammad F, Trivett A, Wang D, Lee DJ. Tissue-specific production of MicroRNA-155 inhibits melanocortin 5 receptor-dependent suppressor macrophages to promote experimental autoimmune uveitis. Eur J Immunol. 2019 11; 49(11):2074-2082. PMID: 31177529.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    11. Lee DJ, Preble J, Lee S, Foster CS, Taylor AW. MC5r and A2Ar Deficiencies During Experimental Autoimmune Uveitis Identifies Distinct T cell Polarization Programs and a Biphasic Regulatory Response. Sci Rep. 2016 11 25; 6:37790. PMID: 27886238.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    12. Lee DJ. Intraocular Implants for the Treatment of Autoimmune Uveitis. J Funct Biomater. 2015 Jul 31; 6(3):650-66. PMID: 26264035.
    13. Lee DJ, Taylor AW. Recovery from experimental autoimmune uveitis promotes induction of antiuveitic inducible Tregs. J Leukoc Biol. 2015 Jun; 97(6):1101-9. PMID: 25877928.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    14. Lee DJ, Taylor AW. Both MC5r and A2Ar are required for protective regulatory immunity in the spleen of post-experimental autoimmune uveitis in mice. J Immunol. 2013 Oct 15; 191(8):4103-11. PMID: 24043903.
      Citations: 44     Fields:    Translation:AnimalsCells
    15. Lee DJ, Taylor AW. Following EAU recovery there is an associated MC5r-dependent APC induction of regulatory immunity in the spleen. Invest Ophthalmol Vis Sci. 2011 Nov 17; 52(12):8862-7. PMID: 21989727.
      Citations: 24     Fields:    Translation:AnimalsCells
    16. Lee DJ, Biros DJ, Taylor AW. Injection of an alpha-melanocyte stimulating hormone expression plasmid is effective in suppressing experimental autoimmune uveitis. Int Immunopharmacol. 2009 Aug; 9(9):1079-86. PMID: 19426838.
      Citations: 29     Fields:    Translation:HumansAnimals
    Lee's Networks
    Click the
    buttons for more information and interactive visualizations!
    Concepts (94)
    Co-Authors (1)
    Similar People (60)
    Same Department Expand Description
    Physical Neighbors