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Mazor, Kathleen
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Chasan-Taber, Lisa
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Bertone-Johnson, Elizabeth
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Wolf, Greg
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Rosal, Milagros
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Post Docs: Postdoctoral Fellow Applications are being accepted for one position. A position is available to develop Cys2His2 zinc finger proteins (ZFPs) for the treatment of monogenic disorders. This project will focus on the creation of ZFPs with novel DNA-binding specificity to recognize sequence elements within genomic loci of therapeutic interest. In collaboration with other laboratories, we will evaluate the activity of these ZFP-based gene therapy reagents in vitro and in vivo in relevant disease models. Applicants will also have the opportunity to learn to apply Cas9 and Cas12a editing systems in vivo.
Rotation Projects: Potential Rotation Projects Improving the Precision of CRISPR/Cas9 nucleases for gene therapy applications: We are working to improve the precision of the CRISPR/Cas9 system to generate nucleases that will cleave at only a single site in the genome. These engineering efforts focus on increasing the DNA-editing precision of Cas9 and using protein engineering to introduce new properties into the nuclease. Much of this work is now transitioning to the use of Cas9 (and Cas12a) protein-RNA complexes. These modified nucleases will then be applied to patient derived cell-culture systems for the targeted repair or inactivation of disease-causing alleles. With the eventual goal of creating therapeutics for Sickle Cell Disease, beta-Thalassemia, HIV, Limb Girdle Muscular Dystrophy, Hermansky Pudlak Syndrome and other monogenic disorders. ex vivo genome editing in CD34+ HSPCs: We are developing improved Cas9 proteins for delivery ex vivo into CD34+ HSPCs for therapeutic application to sickle cell disease and beta-thalassemia. The goal is to modify the hematopoietic stem cells of a patient to complement the loss of function of the beta-globin gene and then return these cells to the patient through an autologous transplant. Development of Cys2His2 Zinc fingers proteins (ZFPs) as targeted therapeutics: We are developing artificial ZFPs for the regulation of target genes to change their gene expression profiles for therapeutic applications.
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Lemon, Stephenie
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Goldberg, Robert
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McManus, David
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Lagu, Tara
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Lindenauer, Peter
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Wint, Jeffrey
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Yonkers, Kimberly
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position in department: Surgery at UMass Chan - Baystate
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HR job title: Assistant Professor
position in organization: UMass Chan – Baystate Regional Campus

Professor
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position in department: Neurology at UMass Chan - Baystate
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sort order: 1
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HR job title: Professor
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Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Preventive And Behavioral Medicine
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HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Adjunct Assistant Professor
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position in department: Surgery at UMass Chan - Baystate
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sort order: 1
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HR job title: Adjunct Assistant Professor
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Adjunct Assistant Professor
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position in department: Dermatology
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HR job title: Adjunct Assistant Professor
position in organization: UMass Chan Medical School

Chief Information Officer
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position in department: Information Technology
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HR job title: Chief Information Officer
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Family Medicine and Community Health
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sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Medicine
position in division: Rheumatology
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Radiology
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sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Evans, Elizabeth
first name: Elizabeth
last name: Evans
full name: Elizabeth A Evans PhD
has faculty rank: ADJUNCT PROFESSOR
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person in primary position: Adjunct Professor
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Adjunct Professor
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position in department: Healthcare Delivery and Population Sciences at UMass Chan - Baystate
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sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan – Baystate Regional Campus

Driban, Jeffrey
first name: Jeffrey
last name: Driban
Featured Videos: https://profiles.umassmed.edu/profile/40402890
full name: Jeffrey B Driban PhD, AT Ret, CSCS
has faculty rank: Professor
latitude: 42.27834540000000
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Person ID: 10247494
person in primary position: Professor
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Professor
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position in division: Plastic Surgery
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HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in division: Vascular Surgery
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HR job title: Professor
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Professor
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HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Surgery
position in division: Plastic Surgery
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Walkey, Allan
first name: Allan
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full name: Allan Jay Walkey MD, MSc
has faculty rank: Professor
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Person ID: 10247602
person in primary position: Professor
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preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/104051488

Medicine at UMass Chan - Lahey
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type: Organization

Surgery at UMass Chan - Lahey
type: Department
type: Organization

https://profiles.umassmed.edu/profile/40402890
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Radiology at UMass Chan - Lahey
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type: Organization

Associate Professor
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position in department: Surgery
position in division: Vascular Surgery
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type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Population and Quantitative Health Sciences
position in division: Preventive And Behavioral Medicine
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Chair and Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
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HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Health System Science
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type: Organization

Neurointerventional Radiology
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type: Organization

Pulmonary Medicine
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Professor Emeritus
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position in division: Epidemiology
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HR job title: Professor Emeritus
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Professor
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position in division: Geriatrics
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Population and Quantitative Health Sciences
position in division: Epidemiology
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in division: Epidemiology
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in division: Epidemiology
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type: Position
HR job title: Professor
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Professor
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position in department: Population and Quantitative Health Sciences
position in division: Biostatistics And Health Services Research
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type: Position
HR job title: Professor
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Associate Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
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type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Orthopedics and Physical Rehabilitation
position in division: Sports
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type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Sports
type: Division
type: Organization

Stroke and Vascular Neurology
type: Division
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Chair and Professor
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position in department: Medicine
position in division: Cardiovascular Medicine
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type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Medicine
position in division: Health System Science
sort order: 1
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Finlay, Andrea
first name: Andrea
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Person ID: 10247736
person in primary position: Associate Professor
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Professor
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position in department: Molecular, Cell and Cancer Biology
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HR job title: Professor
position in organization: UMass Chan Medical School

Tan Chingfen Graduate School of Nursing
type: Department
type: Organization

McAlindon, Timothy
first name: Timothy
last name: McAlindon
full name: Timothy Edward McAlindon MD, MPH, MRCP
has faculty rank: Professor
latitude: 42.27222560000000
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Person ID: 10247852
person in primary position: Professor
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Dani, Sourbha
first name: Sourbha
last name: Dani
full name: Sourbha S Dani MD, MSc, GDCE, CCDS, FACC,FACP
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Person ID: 10247888
person in primary position: Associate Professor
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preferred title: Associate Professor

Associate Professor
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Martinez, Fernando
first name: Fernando
last name: Martinez
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latitude: 42.27525000000000
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Person ID: 10247895
person in primary position: Professor
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Professor
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position in department: Medicine
position in division: Pulmonary Medicine
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HR job title: Professor
position in organization: UMass Chan Medical School

Krings, Timo
first name: Timo
last name: Krings
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latitude: 42.48526100000000
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Person ID: 10247952
person in primary position: Professor
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Goldsweig, Andrew
first name: Andrew
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full name: Andrew Goldsweig MD, MS
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latitude: 42.12294230000000
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Person ID: 10248018
person in primary position: Associate Professor
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preferred title: Associate Professor

Ghogawala, Zoher
first name: Zoher
last name: Ghogawala
full name: Zoher Ghogawala MD, FACS
has faculty rank: Professor
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Person ID: 10248062
person in primary position: Professor
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preferred title: Professor

Associate Professor
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position in department: Medicine at UMass Chan - Baystate
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sort order: 1
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HR job title: Associate Professor
position in organization: UMass Chan – Baystate Regional Campus

Professor
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sort order: 1
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HR job title: Professor
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Maron, Martin
first name: Martin
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Person ID: 10248121
person in primary position: Associate Professor
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Maron, Barry
first name: Barry
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full name: Barry J Maron MD
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Person ID: 10248130
person in primary position: Adjunct Professor
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Adjunct Professor
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HR job title: Adjunct Professor
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Professor
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position in division: Rheumatology
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HR job title: Professor
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Chair and Professor
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sort order: 1
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HR job title: Chair and Professor
position in organization: UMass Chan – Baystate Regional Campus

Reynolds, Matthew
first name: Matthew
last name: Reynolds
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Person ID: 10248173
person in primary position: Professor
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preferred title: Professor

Rowin, Ethan
first name: Ethan
last name: Rowin
full name: Ethan Rowin MD, MBA
has faculty rank: Associate Professor
latitude: 42.48817480000000
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Person ID: 10248175
person in primary position: Associate Professor
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Associate Professor
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HR job title: Associate Professor
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Professor
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sort order: 1
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HR job title: Professor
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Instructor
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Professor
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type: Faculty Rank

Professor Emeritus
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type: Faculty Rank

Assistant Professor
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type: Faculty Rank

Associate Professor
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type: Faculty Rank

Chair And Professor
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Other
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type: Faculty Rank

Professor Emeritus
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position in department: Medicine
position in division: Health System Science
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HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Psychiatry and Behavioral Sciences
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Chair and Professor
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position in department: Psychiatry and Behavioral Sciences
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sort order: 1
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HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Tan Chingfen Graduate School of Nursing
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Population and Quantitative Health Sciences
position in division: Preventive And Behavioral Medicine
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Neurology
position in division: Stroke and Vascular Neurology
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type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Emergency Medicine
position in division: Research
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in division: Health Informatics And Implementation Science
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Ophthalmology and Visual Sciences
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sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Health System Science
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HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Surgery at UMass Chan - Lahey
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sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Assistant Professor
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position in department: Surgery at UMass Chan - Baystate
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sort order: 1
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HR job title: Assistant Professor
position in organization: UMass Chan – Baystate Regional Campus

Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Miller, Jonathan
first name: Jonathan
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full name: Jonathan Eitan Miller MD
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Person ID: 10248393
person in primary position: Assistant Professor
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preferred title: Assistant Professor

Shin, Dong-Soo
first name: Dong-Soo
last name: Shin
full name: Dong-Soo Shin PhD, RN
has faculty rank: ADJUNCT PROFESSOR
Person ID: 10248397
person in primary position: Adjunct Professor
type: Agent
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preferred title: Adjunct Professor

Vanni, Alex
first name: Alex
last name: Vanni
full name: Alex Vanni MD, FACS
has faculty rank: Professor
Person ID: 10248404
person in primary position: Professor
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preferred title: Professor

Associate Professor
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position in department: Medicine at UMass Chan - Lahey
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sort order: 1
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Radiology at UMass Chan - Lahey
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Healthcare Delivery and Population Sciences at UMass Chan - Baystate
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan – Baystate Regional Campus