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Professor
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position in organization: UMass Chan Medical School

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Xue, Wen
first name: Wen
last name: Xue
full name: Wen Xue PhD
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Person ID: 3974
person in primary position: Professor
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Post Docs: We are looking for postdoc candidates with experience in cancer biology, mouse models and genome-engineering. Please email CV and 3 letters of recommendation to Wen.Xue@umassmed.edu.
Rotation Projects: Our lab uses CRISPR tools to speed up cancer gene discovery and disease gene repair. Rotation projects are available to explore experimental techniques such as molecular cloning of CRISPR plasmids, measuring genome-editing efficiency, dissecting mice, and processing of mouse tumor/tissue for histology.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866638

Molecular, Cell and Cancer Biology
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Orthopedics and Physical Rehabilitation
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Family Medicine and Community Health
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Medicine
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Neurology
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Pathology
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Program in Molecular Medicine
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Radiation Oncology
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Radiology
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RNA Therapeutics Institute
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Surgery
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Urology
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Information Technology
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College of Natural Sciences
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Cardiovascular Medicine
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Epidemiology
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Food Science
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Gastroenterology
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Geriatrics
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Health Informatics And Implementation Science
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Hematology/Oncology
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Anatomic Pathology
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Rheumatology
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Vascular Surgery
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UMass Chan Medical School
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University of Massachusetts Amherst
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Rando, Oliver
first name: Oliver
last name: Rando
full name: Oliver J Rando MD, PhD
has faculty rank: Professor
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Endowed Chair Honorary Title: Endowed Chair in Biochemistry and Molecular Biotechnology II
Post Docs: For more information about the Postdoctoral position in Dr. Rando’s lab please use the link provided. Post doc position
Rotation Projects: Rotation projects are available to study chromatin structure and function. Project 1. Measure histone dynamics in yeast. Histone dynamics play major roles in chromatin metabolism and in the inheritance of chromatin states. To measure histone replacement rates in yeast, we have created yeast strains carrying inducible epitope-tagged histones H3 and H2A. Using microarrays, we will measure histone replacement rates in a variety of mutant yeast to ascertain the role of various chromatin remodeling factors in histone exchange reactions. Project 2. Characterize mechanisms for epigenetic inheritance in yeast. We have identified a variety of genes whose expression state in yeast is epigenetically heritable. We will screen the yeast genome for genes that affect the inheritance of these expression patterns. Project 3. Measure histone dynamics in embryonic stem cells. Embryonic stem cells are pluripotent cells that can give rise to every type of cell in the adult animal. The role of chromatin structure in maintaining this pluripotent state is poorly understood, but it appears that stem cell chromatin is exceptionally labile relative to that in differentiated cells. We will create stem cell lines with inducible tagged histones to measure histone replacement rates across the mouse genome.
preferred title: Professor

Schanzer, Andres
first name: Andres
last name: Schanzer
full name: Andres Schanzer MD
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Endowed Chair Honorary Title: Cutler Chair in Vascular and Endovascular Surgery
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Ambros, Victor
first name: Victor
last name: Ambros
full name: Victor R Ambros PhD
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latitude: 42.27913100000000
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Person ID: 1164
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Endowed Chair Honorary Title: Silverman Chair in Natural Sciences
Rotation Projects: Rotations <p >Project 1: Genetic screens for proteins that modify or regulate the activity of microRNAs in C. elegans.
preferred title: Professor

Gao, Guangping
first name: Guangping
last name: Gao
full name: Guangping Gao PhD
has faculty rank: Chair And Professor
latitude: 42.27714780000000
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Person ID: 1177
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Endowed Chair Honorary Title: Penelope Booth Rockwell Chair in Biomedical Research
Lab URL: https://www.umassmed.edu/gaolab/
Summary: Focus: Adeno-associated virus vector mediated gene transfer for gene therapy, gene therapy of inherited neurodegenerative Canavan Disease
preferred title: Chair and Professor

Brown, Robert
first name: Robert
last name: Brown
full name: Robert H Brown MD, DPhil
has faculty rank: Professor
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Person ID: 1239
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Endowed Chair Honorary Title: Donna M. and Robert J. Manning Chair in Neurosciences
Lab URL: https://www.umassmed.edu/brownlab/
Summary: Dr. Brown’s laboratory has focused on the identification of gene defects that elucidate the molecular pathogenesis of selected neuromuscular diseases including amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig’s disease), muscular dystrophy, adrenoleukodystrophy, hereditary neuropathy and hyperkalemic periodic paralysis.
preferred title: Professor

Hutchinson, Lloyd
first name: Lloyd
last name: Hutchinson
Featured Videos: https://profiles.umassmed.edu/profile/28867192
full name: Lloyd Hutchinson PhD
has faculty rank: Associate Professor
latitude: 42.27672100000000
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Person ID: 1241
person in primary position: Associate Professor
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Gao, Fen-Biao
first name: Fen-Biao
last name: Gao
full name: Fen-Biao Gao PhD
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Person ID: 1368
person in primary position: Professor
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Endowed Chair Honorary Title: Governor Paul Cellucci Chair in Neuroscience Research
Lab URL: https://www.umassmed.edu/fen-biaogaolab
Rotation Projects: Project 1: Dervelop RNA-based therapies for frontotemporal dementia (FTD) and related disroders. Project 2: Study pathogenic mechanisms of FTD and related disorders in mouse models.
Summary: Our lab uses a combination of molecular, cellular, genetic, and behavioral approaches to further dissect the pathogenic mechanisms of Frontotemporal Dementia and Amyotrophic Lateral Sclerosis with a focus on mutant CHMP2B, progranulin and C9ORF72. We will identify common underlying pathways as potential targets for therapeutic interventions.
preferred title: Professor

Mazor, Kathleen
first name: Kathleen
last name: Mazor
full name: Kathleen Mazor EdD
has faculty rank: Professor Emeritus
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Person ID: 217
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Shultz, Leonard
first name: Leonard
last name: Shultz
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Zierath, Juleen
first name: Juleen
last name: Zierath
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person in primary position: Adjunct Professor
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Lapane, Kate
first name: Kate
last name: Lapane
full name: Kate L Lapane PhD
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latitude: 42.27587600000000
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Person ID: 3252
person in primary position: Professor
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Puri, Ajit
first name: Ajit
last name: Puri
full name: Ajit Singh Puri MD, DM, DMRE
has faculty rank: Professor
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longitude: -71.76233800000000
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Person ID: 3253
person in primary position: Professor
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preferred title: Professor

Henninger, Nils
first name: Nils
last name: Henninger
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full name: Nils Henninger MD, PhD
has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 3265
person in primary position: Associate Professor
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Summary: Dr. Henninger is a vascular neurologist with research interest in the neurobiology of axonal injury associated with traumatic brain injury and its contribution to functional outcome.
preferred title: Associate Professor

Heneka, Michael
first name: Michael
last name: Heneka
full name: Michael Thomas Heneka MD
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latitude: 50.70274210000000
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Person ID: 3432
person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Szabo, Gyongyi
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo MD, PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27636250000000
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Person ID: 36
person in primary position: Adjunct Professor
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Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
preferred title: Adjunct Professor

Lian, Jane
first name: Jane
last name: Lian
full name: Jane B Lian PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27723620000000
longitude: -71.76070940000000
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Person ID: 370
person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Xiao, Hang
first name: Hang
last name: Xiao
full name: Hang Xiao PhD
has faculty rank: Associate Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3795
person in primary position: Associate Professor
type: Agent
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preferred title: Associate Professor

Wolf, Greg
first name: Greg
last name: Wolf
Twitter: https://profiles.umassmed.edu/profile/28867023
full name: Greg Wolf
has faculty rank: Other
latitude: 42.28346030000000
longitude: -71.72665900000000
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Person ID: 3864
person in primary position: Chief Information Officer
type: Agent
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preferred title: Chief Information Officer
webpage: https://profiles.umassmed.edu/profile/28866533

Zamore, Phillip
first name: Phillip
last name: Zamore
full name: Phillip D Zamore PhD
has faculty rank: Chair And Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
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Person ID: 418
person in primary position: Chair and Professor
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Endowed Chair Honorary Title: Gretchen Stone Cook Chair in Biomedical Sciences
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Zamore for additional details
Rotation Projects: Potential Rotation Projects Our laboratory uses a combination of biochemistry, cell biology, and genetics to dissect the RNAi pathway. A rotation project is available to explore the mechanisms that underlie the RNAi phenomenon or the biological pathways in which RNAi enzymes participate in flies, mice and humans.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866555
webpage: https://profiles.umassmed.edu/profile/28866537
webpage: https://profiles.umassmed.edu/profile/28866541

Goldberg, Robert
first name: Robert
last name: Goldberg
full name: Robert Joel Goldberg PhD
has faculty rank: Professor Emeritus
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Person ID: 78
person in primary position: Professor Emeritus
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FitzGerald, Thomas
first name: Thomas
last name: FitzGerald
full name: Thomas J FitzGerald MD
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latitude: 42.27525000000000
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Person ID: 85
person in primary position: Chair and Professor
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Endowed Chair Honorary Title: UMass Memorial Chair in Radiation Oncology
preferred title: Chair and Professor

Shaw, Leslie
first name: Leslie
last name: Shaw
full name: Leslie M Shaw PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 900
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webpage: https://profiles.umassmed.edu/profile/28866558

Mercurio, Arthur
first name: Arthur
last name: Mercurio
full name: Arthur M Mercurio PhD
has faculty rank: Professor
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Person ID: 901
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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
preferred title: Professor

McManus, David
first name: David
last name: McManus
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latitude: 42.27525000000000
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Person ID: 994
person in primary position: Chair and Professor
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Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
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UMass Chan – Baystate Regional Campus
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Ito Fukunaga, Mayuko
first name: Mayuko
last name: Ito Fukunaga
full name: Mayuko Ito Fukunaga MD, FCCP
has faculty rank: Assistant Professor
latitude: 42.27525000000000
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Person ID: 4585
person in primary position: Assistant Professor
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preferred title: Assistant Professor

Singh, Sonal
first name: Sonal
last name: Singh
full name: Sonal Singh MD, MPH
has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 4649
person in primary position: Associate Professor
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preferred title: Associate Professor
webpage: https://profiles.umassmed.edu/profile/28866602

Johnson, Mark
first name: Mark
last name: Johnson
full name: Mark Damone Johnson MD, PhD
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latitude: 42.27525000000000
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Person ID: 4642
person in primary position: Chair and Professor
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Endowed Chair Honorary Title: Maroun Semaan Chair in Neurosurgery
preferred title: Chair and Professor

Mittal, Kriti
first name: Kriti
last name: Mittal
full name: Kriti Mittal MD
has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 4703
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preferred title: Associate Professor

Associate Professor
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position in department: College of Natural Sciences
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position in organization: University of Massachusetts Amherst

Lindenauer, Peter
first name: Peter
last name: Lindenauer
full name: Peter K Lindenauer MD, MSc
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latitude: 42.12711190000000
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Emmerick, Isabel
first name: Isabel
last name: Emmerick
full name: Isabel Cristina Martins Emmerick PhD
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ADJUNCT PROFESSOR
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Lou, Feiran
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Gurwitz, Jerry
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latitude: 42.27525000000000
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Person ID: 5308
person in primary position: Professor
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Endowed Chair Honorary Title: Dr. John Meyers Professor in Primary Care Medicine
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Sorokin, Igor
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Usmani, Saad
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latitude: 42.07492460000000
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Population and Quantitative Health Sciences
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Neurological Surgery
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Bankier, Alexander
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last name: Bankier
full name: Alexander A. Bankier MD, PhD
has faculty rank: Professor
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Person ID: 5766
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Nason, Katie
first name: Katie
last name: Nason
full name: Katie Nason MD, MPH
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latitude: 42.12294230000000
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Person ID: 10246713
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Biochemistry and Molecular Biotechnology
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Lin, Honghuang
first name: Honghuang
last name: Lin
full name: Honghuang Lin PhD
has faculty rank: Professor
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https://profiles.umassmed.edu/profile/28866533
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https://profiles.umassmed.edu/profile/28866537
type: URLLink
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Medicine at UMass Chan - Lahey
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Shin, Dong-Soo
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