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Molecular, Cell and Cancer Biology
type: Department
type: Organization

Orthopedics and Physical Rehabilitation
type: Department
type: Organization

Medicine
type: Department
type: Organization

Pathology
type: Department
type: Organization

Program in Molecular Medicine
type: Department
type: Organization

Radiology
type: Department
type: Organization

RNA Therapeutics Institute
type: Department
type: Organization

Surgery
type: Department
type: Organization

College of Natural Sciences
type: Department
type: Organization

Cardiovascular Medicine
type: Division
type: Organization

Chemistry
type: Division
type: Organization

Epidemiology
type: Division
type: Organization

Food Science
type: Division
type: Organization

Vet & Animal Sciences
type: Division
type: Organization

Veterinary & Animal Sciences
type: Division
type: Organization

Gastroenterology
type: Division
type: Organization

Geriatrics
type: Division
type: Organization

Health Informatics And Implementation Science
type: Division
type: Organization

Vascular Surgery
type: Division
type: Organization

UMass Chan Medical School
type: Organization

University of Massachusetts Amherst
type: Organization

Messina, Louis
first name: Louis
last name: Messina
full name: Louis M Messina MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 1058
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Johnnie Ray Cox Term Chair in Biomedical Research
preferred title: Professor

Flotte, Terence
first name: Terence
last name: Flotte
full name: Terence R Flotte MD
has faculty rank: Professor
latitude: 42.27721310000000
longitude: -71.76076230000000
Person ID: 1094
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Elisabeth Chair for the Dean of Medicine
preferred title: Professor

Gore, Joel
first name: Joel
last name: Gore
full name: Joel M Gore MD
has faculty rank: Professor Emeritus
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 112
person in primary position: Professor Emeritus
type: Agent
type: Person
preferred title: Professor Emeritus

Zhu, Lihua
first name: Lihua
last name: Zhu
full name: Lihua Zhu PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 1134
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Baehrecke, Eric
first name: Eric
last name: Baehrecke
full name: Eric H Baehrecke PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1148
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Our Danny Cancer Fund Chair in Biomedical Research II
Post Docs: Postdoctoral positions are available for this lab. Please contact Eric Baehrecke directly, 508-856-6733 or via email, Eric.Baehrecke@umassmed.edu
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866477

Kelliher, Michelle
first name: Michelle
last name: Kelliher
full name: Michelle A Kelliher PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 115
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Our Danny Cancer Fund Chair in Biomedical Research I
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Kelliher for additional details.
Rotation Projects: Please visit the Kelliher Lab website at: http://labs.umassmed.edu/kelliherlab/ to learn more about our current research areas. 1. Identify genes/pathways that mediate leukemia-initiating cell survival 2. Understand the molecular basis of glucocorticoid resistance in leukemia 3. Examine contribution of RIPK1 kinase in inflammatory and autoimmune disease mouse models. 4. Reveal tissue-specific roles for RIPK1 in cell death and inflammation. Use conditional Ripk1 allele to investigate effects of Ripk1 deletion in liver, pancreas and antigen presenting cells.
preferred title: Professor

Ambros, Victor
first name: Victor
last name: Ambros
full name: Victor R Ambros PhD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1164
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Silverman Chair in Natural Sciences
Rotation Projects: Rotations <p >Project 1: Genetic screens for proteins that modify or regulate the activity of microRNAs in C. elegans.
preferred title: Professor

Gao, Guangping
first name: Guangping
last name: Gao
full name: Guangping Gao PhD
has faculty rank: Chair And Professor
latitude: 42.27714780000000
longitude: -71.76564580000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1177
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Penelope Booth Rockwell Chair in Biomedical Research
Lab URL: https://www.umassmed.edu/gaolab/
Summary: Focus: Adeno-associated virus vector mediated gene transfer for gene therapy, gene therapy of inherited neurodegenerative Canavan Disease
preferred title: Chair and Professor

Mao, Junhao
first name: Junhao
last name: Mao
full name: Junhao Mao PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
Person ID: 1191
person in primary position: Professor
type: Agent
type: Person
Post Docs: Postdoctoral positions are available for this lab. Please contact Junhao Mao directly, 508-856-4149 or via email, Junhao.Mao@umassmed.edu
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866544

Kim, Jason
first name: Jason
last name: Kim
email address: 58C26ZrU2RKPa77JyAcHbVy72ngcdw==
full name: Jason K Kim PhD
has faculty rank: Professor
latitude: 42.27714780000000
longitude: -71.76564580000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1215
person in primary position: Professor
type: Agent
type: Person
Rotation Projects: Lab rotations are currently available in this lab. Please contact Dr. Kim.
Summary: My research for almost 30 years has focused on obesity, insulin resistance, and type 2 diabetes and explores the molecular link between inflammation and insulin resistance using transgenic mice with elegant in vivo metabolic experiments and molecular approaches. My research also investigates the role of inflammation and altered metabolism in diabetic heart disease.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866556

Kiefe, Catarina
first name: Catarina
last name: Kiefe
full name: Catarina I Kiefe PhD, MD
has faculty rank: Professor
latitude: 42.27767280000000
longitude: -71.76163720000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1282
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Melvin S. and Sandra L. Cutler Chair in Biomedical Research
preferred title: Professor

Swain, Susan
first name: Susan
last name: Swain
full name: Susan L Swain PhD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 1360
person in primary position: Professor
type: Agent
type: Person
Post Docs: An entry level postdoctoral position is open immediately in the laboratory of Dr. Susan L. Swain to study the factors that control the development and survival of CD4 and CD8 T cell memory. Graduate student experience with tissue culture, in vitro assay, flow cytometry, experience in mouse models on infectious disease and a knowledge of cellular and molecular immunology are all strongly desired.
Rotation Projects: <p >Rotations: Projects in the following areas <p >CD4 T cell memory. We can generate in vitro CD4 T cells that are for all extents and purposes identical to the memory CD4 T cells observed in vivo. In situ memory CD4 T cells persist at very low frequency and in most instances it is difficult to analyze them thoroughly using tetramer or multimer reagents both because of their low frequency and the relatively low specific affinity of the Class II reagents for the TcR. Being able to generate “recent” memory cells in vitro gives us the opportunity to analyze in detail the mechanisms by which memory CD4 T cells may contribute to secondary immunity and immune protection. Once identified. will determine if particular pathways are relevant in situ. We have discovered that memory CD4 T cells are superior in protection to those from the primary response and that they display pleitropic functions that have not been previously identified. <p > Cytotoxic CD4 Effectors. One unexpected function of CD4 T cells we identified is robust, perforin-dependent cytotoxic activity (7, 16). Cytotoxic activity by CD4 T cells has been reported in response to several infections, but its significance has not heretofore been established. We find that “Th1 polarized” CD4 effectors and more relevantly the CD4 effectors found in the lung following influenza infection, are able to kill infected or peptide-pulsed Class II-bearing targets and we find that this perforin dependent activity can work together with antibody to provide protection against lethal influenza challenge in otherwise unprimed mice (17). We also will determine when memory CD4 T cells re-express cytotoxic activity following in vivo challenge and how cytotoxic killing contributes to the memory cell mediated protection. We want to analyze how the program of cytotoxicity is induced in these “ThCTL”. <p > Memory CD4 Cells Enhance an Innate Response. Memory cells can act by becoming secondary effectors but they are best characterized by …
preferred title: Professor

Gao, Fen-Biao
first name: Fen-Biao
last name: Gao
full name: Fen-Biao Gao PhD
has faculty rank: Professor
latitude: 42.27694690000000
longitude: -71.76568470000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1368
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Governor Paul Cellucci Chair in Neuroscience Research
Lab URL: https://www.umassmed.edu/fen-biaogaolab
Rotation Projects: Project 1: Dervelop RNA-based therapies for frontotemporal dementia (FTD) and related disroders. Project 2: Study pathogenic mechanisms of FTD and related disorders in mouse models.
Summary: Our lab uses a combination of molecular, cellular, genetic, and behavioral approaches to further dissect the pathogenic mechanisms of Frontotemporal Dementia and Amyotrophic Lateral Sclerosis with a focus on mutant CHMP2B, progranulin and C9ORF72. We will identify common underlying pathways as potential targets for therapeutic interventions.
preferred title: Professor

Latz, Eicke
first name: Eicke
last name: Latz
full name: Eicke Latz MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27985300000000
longitude: -71.79190270000000
Person ID: 153
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Bergmann, Andreas
first name: Andreas
last name: Bergmann
full name: Andreas Bergmann PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
Person ID: 1651
person in primary position: Professor
type: Agent
type: Person
Post Docs: Please contact the Human Resources at UMass for openings in Dr. Bergmann's lab.
preferred title: Professor

Trivedi, Chinmay
first name: Chinmay
last name: Trivedi
Twitter: https://profiles.umassmed.edu/profile/28867131
full name: Chinmay M Trivedi MD, PhD
has faculty rank: Professor
latitude: 42.27834540000000
longitude: -71.76387620000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1655
person in primary position: Professor
type: Agent
type: Person
Lab URL: https://www.umassmed.edu/trivedilab/
Post Docs: A Postdoctoral position is available in the Trivedi lab to study roles of novel chromatin and epigenetic modifications during cardiovascular development and disease (for details of our research: The Journal of Clinical Investigation, Science Advances, Journal of Experimental Medicine, ATVB, Human Molecular Genetics, Journal of Biological Chemistry). Candidates with a PhD in Biochemistry, Molecular Biology, Stem Cell Biology or Developmental Biology are encouraged to apply. Previous experience with mice handling and biochemistry-molecular biology-epigenetics related techniques such as ChIP-seq is strongly desired. Candidate will be required to learn new techniques in the area of translational biology to advance their project.
Rotation Projects: Rotation Projects: Please contact Chinmay Trivedi (chinmay.trivedi@umassmed.edu) for information regarding potential rotation projects (for details - research performed by graduate students in the trivedi lab: The Journal of Clinical Investigation, Science Advances, Journal of Experimental Medicine, JCI Insight, ATVB, Human Molecular Genetics, Journal of Biological Chemistry). We will develop a specific rotation project based on student's interest, background, and goals of the rotation. Students can rotate either for a half- or full-semester.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866584

Luban, Jeremy
first name: Jeremy
last name: Luban
full name: Jeremy Luban MD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1684
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: David J. Freelander Memorial Professor in AIDS Research
Post Docs: PostDoc Position available
Rotation Projects: Lab rotation position is available
preferred title: Professor

Fitzgerald, Katherine
first name: Katherine
last name: Fitzgerald
full name: Katherine A Fitzgerald PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 202
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Worcester Foundation for Biomedical Research Chair III
Rotation Projects: Please email Kate.Fitzgerald@umassmed.edu if you are interested in rotations.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866427
webpage: https://profiles.umassmed.edu/profile/28866493

Corvera, Silvia
first name: Silvia
last name: Corvera
full name: Silvia Corvera MD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 220
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Endowed Chair in Diabetes Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Corvera for additional details.
Rotation Projects: Rotation Projects Our rotation projects are in the area of diabetes and obesity, and we are interested in basic mechanisms of cell proliferation, differentiation and communication. Diabetes is highly correlated with obesity, but why obesity causes disease in some humans and not others is not understood. Amazingly, we still don’t understand how adipose tissue grows in human adults. A better understanding of this fascinating process can give us insight into basic mechanisms of cell growth, differentiation and communication, as well as mechanisms of disease, not only diabetes but also cancer and developmental defects. During your rotation, you will work on an important piece of a larger project, that has a well-defined outcome. Thus, your successful completion of the rotation project will allow you to be included at the time of publication of the work. Project 1: Adipose tissue is not only formed by adipocytes, but by other cells such as endothelial, mural and immune cells. Also, there are multiple kinds of adipocytes with different functions. We have recently developed conditions to develop adipose tissue from humans in-vitro (adipose tissue “organoids”). From this tissue we have been able to separated single cells, and find that they grow into different kinds of clones. We are now conducting RNAseq on >300 of those clones, to determine how many cell types exist in human adipose tissue, and what their roles are. In this rotation, you will be able to analyze RNAseq data to define what genes characterize these cells, and you will use virus transduction to create immortalized cells for further study. Project 2: Adipose tissue has many functions besides storing and releasing lipids. It also has to coordinate metabolism in the whole body. We have found that human “beige” adipose tissue, which is found in people who are metabolically healthy, expresses genes for secreted factors that communicate with the immune system and the brain. These include IL-33 and enkephalins. In t…
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866593

Shultz, Leonard
first name: Leonard
last name: Shultz
full name: Leonard Donald Shultz PhD
has faculty rank: Professor
latitude: 44.36637960000000
longitude: -68.19692870000000
Person ID: 2863
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Czech, Michael
first name: Michael
last name: Czech
full name: Michael Paul Czech PhD
has faculty rank: Professor Emeritus
latitude: 42.27913450000000
longitude: -71.76550630000000
Person ID: 289
person in primary position: Professor Emeritus
type: Agent
type: Person
Endowed Chair Honorary Title: Isadore and Fannie Foxman Chair in Medical Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Czech for additional details.
Rotation Projects: Mentoring……………………………………………………………………………………………………… The Czech laboratory is active in mentoring graduate students and postdoctoral fellows. Many former student and postdoctoral trainees of the Czech laboratory are now internationally recognized professors at major universities and medical schools. These former lab members include: Paul Pilch, Professor of Biochemistry, Boston University School of Medicine Jeffrey Pessin, Professor and Director of the Diabetes Center, Einstein College of Medicine Joan Massague, Director, Sloan Kettering Institute Roger Davis, HHMI investigator and Professor of Molecular Medicine, UMASS Medical School Silvia Corvera, Professor of Molecular Medicine, Co-Director of the MD/PhD Program, UMASS Medical School Carla Greenbaum, Vice Chair and Director of Clinical Research, Benaroya Research Institute Jes Klarlund, Professor of Ophthalmology, University of Pittsburgh Medical Center Rob Lewis, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Richard MacDonald, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Assia Shisheva, Professor of Physiology, Wayne State School of Medicine. Mark Sleeman, Professor of Physiology, Monash University, Australia John Harris, Associate Professor of Medicine, UMASS Medical School Zhen Jiang, Associate Professor of Pharmacology and Medicine, Boston University Vishu Puri, Professor of Biomedical Sciences, Ohio University Olga Gupta, Assistant Professor of Pediatrics and Medicine, University of Texas Southwestern Medical Center Tim Fitzgibbons, Assistant Professor of Medicine, UMASS Medical School Myriam Aouadi, Assistant Professor, Integrated Cardio Metabolic Centre, Karolinska Institute Adilson Guilherme, Associate Professor, University of Massachusetts Medical School Our laboratory currently offers graduate student Rotation Projects (examples below and others available) and Thesis Research …
preferred title: Professor Emeritus

Dobson, James
first name: James
last name: Dobson
full name: James G Dobson PhD
has faculty rank: Professor Emeritus
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 303
person in primary position: Professor Emeritus
type: Agent
type: Person
preferred title: Professor Emeritus

Davis, Roger
first name: Roger
last name: Davis
full name: Roger J Davis PhD, FRS
has faculty rank: Chair And Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 3130
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: H. Arthur Smith Chair in Cancer Research
Rotation Projects: Rotation Projects Laboratory rotations are available to study signal mammalian transduction mechanisms. Several projects are available, including studies of protein kinase cascades, gene expression, the cell cycle, and apoptosis. Targeted gene disruption approaches in mice combined with biochemical and molecular biology studies will be examined.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866429

Zierath, Juleen
first name: Juleen
last name: Zierath
full name: Juleen R Zierath PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 3151
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Heneka, Michael
first name: Michael
last name: Heneka
full name: Michael Thomas Heneka MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 50.70274210000000
longitude: 7.10034010000000
Person ID: 3432
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Golenbock, Douglas
first name: Douglas
last name: Golenbock
full name: Douglas T Golenbock MD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 345
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Neil and Margery Blacklow Chair in Infectious Diseases and Immunology
preferred title: Professor

Szabo, Gyongyi
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo MD, PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27636250000000
longitude: -71.76564740000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 36
person in primary position: Adjunct Professor
type: Agent
type: Person
Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
preferred title: Adjunct Professor

Lian, Jane
first name: Jane
last name: Lian
full name: Jane B Lian PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27723620000000
longitude: -71.76070940000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 370
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Osborne, Barbara
first name: Barbara
last name: Osborne
full name: Barbara A Osborne PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3725
person in primary position: MCB Director
type: Agent
type: Person
preferred title: MCB Director

Rotello, Vincent
first name: Vincent
last name: Rotello
full name: Vincent Rotello PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3741
person in primary position: Department Head
type: Agent
type: Person
preferred title: Department Head

Visconti, Pablo
first name: Pablo
last name: Visconti
full name: Pablo Visconti PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3766
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Mager, Jesse
first name: Jesse
last name: Mager
full name: Jesse Mager PhD
has faculty rank: Associate Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3787
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Pederson, Thoru
first name: Thoru
last name: Pederson
full name: Thoru Pederson PhD
has faculty rank: Professor Emeritus
latitude: 42.28050130000000
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person in primary position: Professor Emeritus
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Endowed Chair Honorary Title: Vitold Arnett Professor of Cell Biology
Rotation Projects: Background for Student Rotation Projects <p >See Politz, Hogan and Pederson (2009) and Politz et al. (2005) in the above list. The novel microRNA work may be the most suitable for student rotations. Potential Rotation Projects <p >Are the nucleolar microRNAs pri-, pre- or mature? <p >Are they complexed with other nucleolar RNAs? <p >Do the cell cycle related proteins in the nucleolus exist as heterotypic complexes? <p >Does the nucleolus of human embryonic stem cells also share these features (which we have so far looked for, and found, only in transformed human cell lines)? <p >Can vanadium tagging be used to detect specific proteins by electron microscopy, perhaps exceeding the limitations of immuno-EM?
preferred title: Professor Emeritus

Xiao, Hang
first name: Hang
last name: Xiao
full name: Hang Xiao PhD
has faculty rank: Associate Professor
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person in primary position: Associate Professor
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preferred title: Associate Professor

Donahue, J.
first name: J.
last name: Donahue
full name: J. Kevin Donahue MD
has faculty rank: Professor
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Person ID: 3838
person in primary position: Professor
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Endowed Chair Honorary Title: David J. and Barbara D. Milliken Professor in Preventive Cardiology
preferred title: Professor

Tisminetzky, Mayra
first name: Mayra
last name: Tisminetzky
full name: Mayra S Tisminetzky MPH, MD, PhD
has faculty rank: Associate Professor
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Person ID: 3857
person in primary position: Associate Professor
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Summary: Associate Professor in the Division of Geriatric Medicine in the Department of Medicine at UMMS Chan. Her research focuses on the magnitude, management, and clinical outcomes associated with the presence of multiple chronic conditions in older adults (MCC). I have been awarded a NIA RO1 grant to examine the treatment patterns of selected therapies in patients with heart failure and MCC.
preferred title: Associate Professor

Brehm, Michael
first name: Michael
last name: Brehm
full name: Michael A Brehm PhD
has faculty rank: Professor
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Person ID: 474
person in primary position: Professor
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Endowed Chair Honorary Title: Harvey A. Shultz Chair in Diabetes
preferred title: Professor

Imbalzano, Anthony
first name: Anthony
last name: Imbalzano
full name: Anthony N Imbalzano PhD
has faculty rank: Professor
latitude: 42.27767280000000
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Person ID: 507
person in primary position: Professor
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Post Docs: Please contact Dr. Imbalzano to discuss the possibility of a postdoctoral training.See lab research interests and publications for recent topics of research. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
Rotation Projects: Please contact Dr. Imbalzano to discuss the possibility of a rotation project. Rotation projects are generally based on current work and tailored to the interests of the student. See lab research interests and publications for recent topics. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
preferred title: Professor

Richter, Joel
first name: Joel
last name: Richter
Featured Videos: https://profiles.umassmed.edu/profile/28867186
full name: Joel Richter PhD
has faculty rank: Professor
latitude: 42.27913100000000
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Person ID: 554
person in primary position: Professor
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Endowed Chair Honorary Title: Arthur F. Koskinas Chair in Neuroscience
Rotation Projects: Many rotation projects are available so please inquire.
preferred title: Professor

McCollum, Dannel
first name: Dannel
last name: McCollum
full name: Dannel McCollum PhD
has faculty rank: Professor
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Person ID: 561
person in primary position: Professor
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. McCollum for additional details.
Rotation Projects: Rotation Projects Analog sensitive LATS kinase: The goal of this project is to use CRISPR based genome modification to make mutations in the endogenous LATS kinase that cause it to be inhibited by a synthetic ATP analog. This will allow LATS kinase activity to be turned on and off using the ATP analog. The analog sensitive cell line will be a valuable tool for studying Hippo pathway responses to various stimuli and will be used to test whether dephosphorylation of LATS substrates is an important regulatory mechanism. This project will also set the stage for future experiments to create mice that have analog sensitive versions of LATS. These mice will be used to test whether LATS inhibition is a viable treatment for regenerative therapies for the heart, gut, pancreas and other organs. TRIP6 and Angiomotin interacting proteins: We know that cells monitor their mechanical environment by sensing F-actin levels and by measuring tension at cell-cell junctions. We have identified angiomotins as sensors for F-actin and the TRIP6 protein as part of a tension sensor at cell-cell junctions. However, to understand how these sensors work, we need know the network of proteins that they each interact with, and how those networks change in response to mechanical perturbations. To do this we will fuse each sensor to the promiscuous biotin ligase protein BirA, and express the fusion proteins in cells under various conditions. The biotin ligase will label proteins in close proximity with biotin. Labeled proteins will be purified and analyzed by mass spectrometry, and the spectrum of interacting partners under different conditions will be compared.
preferred title: Professor

Ip, Yicktung
first name: Yicktung
last name: Ip
full name: Yicktung T Ip PhD
has faculty rank: Professor
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Person ID: 609
person in primary position: Professor
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Ip for additional details.
Rotation Projects: Rotation Projects Project #1: Mechanistic study of isolated mutants that show abnormal intestinal stem cell division phenotypes. Project #2:Perform transgenic RNAi-based genetic screen for genes required for intestinal stem cell response to tissue damage.
preferred title: Professor

Greiner, Dale
first name: Dale
last name: Greiner
full name: Dale L Greiner PhD
has faculty rank: Professor
latitude: 42.27913100000000
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Person ID: 612
person in primary position: Professor
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Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
preferred title: Professor

Pazour, Gregory
first name: Gregory
last name: Pazour
full name: Gregory J Pazour PhD
has faculty rank: Professor
latitude: 42.27913100000000
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Person ID: 621
person in primary position: Professor
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Rotation Projects: Potential Rotation Projects Rotation projects in my laboratory will involve questions of how cilia are assembled and the function these organelles play in mammals. Projects vary depending on ongoing work in the laboratory and interests of the rotation student. Rotations in my laboratory can give students exposure to a range of techniques from mouse breeding and histological analysis of mouse tissues to mammalian cell culture and other cell biological techniques.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/41661165

Craig, Roger
first name: Roger
last name: Craig
full name: Roger W Craig PhD
has faculty rank: Professor
latitude: 42.27525000000000
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Person ID: 73
person in primary position: Professor
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Craig for additional details.
Rotation Projects: Potential Rotation Projects Project #1: Lipid-Layer Protein Crystallization for Electron Microscopy.While individual protein molecules can be readily visualized by EM, structural information is greatly enhanced if the molecules can by crystallized into 2-dimensional ordered arrays. Methods for achieving this are well established, making use of lipid monolayers at an air-water interface. Follow literature methods to crystallize "standard" proteins using the lipid-layer method. Observe results by electron microscopy following negative staining. If time permits, carry out preliminary image processing of micrographs and/or crystallization of unknown proteins. Techniques to be learned: lipid layer crystallization methods; grid preparation; use of electron microscope; image processing.
preferred title: Professor

Lawson, Nathan
first name: Nathan
last name: Lawson
full name: Nathan Lawson PhD
has faculty rank: Professor
latitude: 42.27587600000000
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Person ID: 755
person in primary position: Professor
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Rotation Projects: Rotation Projects Please contact Nathan Lawson (nathan.lawson@umassmed.edu) for information regarding potential rotation projects. For information concerning recent research in the lab, please see:lawsonlab.umassmed.edu/research.html
preferred title: Professor

Goldberg, Robert
first name: Robert
last name: Goldberg
full name: Robert Joel Goldberg PhD
has faculty rank: Professor Emeritus
latitude: 42.27525000000000
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Person ID: 78
person in primary position: Professor Emeritus
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preferred title: Professor Emeritus

Shaw, Leslie
first name: Leslie
last name: Shaw
full name: Leslie M Shaw PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 900
person in primary position: Professor
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preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866558

Mercurio, Arthur
first name: Arthur
last name: Mercurio
full name: Arthur M Mercurio PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
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Person ID: 901
person in primary position: Professor
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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
preferred title: Professor

Guertin, David
first name: David
last name: Guertin
Twitter: https://profiles.umassmed.edu/profile/28867128
full name: David A Guertin PhD
has faculty rank: Professor
latitude: 42.27913100000000
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Person ID: 99
person in primary position: Professor
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr.Guertin for additional details.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866529

McManus, David
first name: David
last name: McManus
full name: David D McManus MD
has faculty rank: Chair And Professor
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Person ID: 994
person in primary position: Chair and Professor
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Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
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UMass Chan – Baystate Regional Campus
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Shim, Jae-Hyuck
first name: Jae-Hyuck
last name: Shim
full name: Jae-Hyuck Shim PhD
has faculty rank: Professor
latitude: 42.27767280000000
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Person ID: 4421
person in primary position: Professor
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Post Docs: Jungmin Kim
Post Docs: Zheni Stavre
Post Docs: Chujiao Lin
Post Docs: Sachin Ramdas
Post Docs: Aijaz John
Post Docs: Yeon-Suk Yang
Post Docs: Eun-Hye Son
Post Docs: Zhihao Chen
Post Docs: Tadatoshi Sato
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866423

Associate Professor
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ADJUNCT PROFESSOR
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Balsam, Leora
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Population and Quantitative Health Sciences
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Lotfi, Amir
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Biochemistry and Molecular Biotechnology
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Lin, Honghuang
first name: Honghuang
last name: Lin
full name: Honghuang Lin PhD
has faculty rank: Professor
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Medicine at UMass Chan - Baystate
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Professor
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Adjunct Professor
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Professor
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Professor
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Professor
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Adjunct Professor
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Professor
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Professor
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Professor Emeritus
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Professor
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Professor
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Professor
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Professor
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Professor
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Chair and Professor
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Professor
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Professor
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Medicine at UMass Chan - Lahey
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Emergency Medicine at UMass Chan - Lahey
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Radiology at UMass Chan - Lahey
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Basic Pathology
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Endocrinology & Diabetes
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Health System Science
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Infectious Diseases
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Innate Immunity
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Orthopedics Research
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Professor Emeritus
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Professor
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Adjunct Professor
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Professor
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Professor
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Professor
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Professor
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Adjunct Professor
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Professor
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Cardio Thoracic Surgery
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Chair and Professor
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https://profiles.umassmed.edu/profile/41661165
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Professor
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Professor
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Professor
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Microbiology
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Professor Emeritus
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Professor
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Goldsweig, Andrew
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Wang, Erik
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Assistant Professor
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Associate Professor
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Maron, Martin
first name: Martin
last name: Maron
full name: Martin S Maron MD, MSPH
has faculty rank: Associate Professor
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Person ID: 10248121
person in primary position: Associate Professor
type: Agent
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preferred title: Associate Professor

Maron, Barry
first name: Barry
last name: Maron
full name: Barry J Maron MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.48526100000000
longitude: -71.20221980000000
Person ID: 10248130
person in primary position: Adjunct Professor
type: Agent
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preferred title: Adjunct Professor

Adjunct Professor
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position in department: Medicine at UMass Chan - Lahey
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HR job title: Adjunct Professor
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Professor
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position in department: Program in Molecular Medicine
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor Emeritus
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position in department: Program in Molecular Medicine
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HR job title: Professor Emeritus
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Professor
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HR job title: Professor
position in organization: UMass Chan Medical School

Rowin, Ethan
first name: Ethan
last name: Rowin
full name: Ethan Rowin MD, MBA
has faculty rank: Associate Professor
latitude: 42.48817480000000
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Person ID: 10248175
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Associate Professor
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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type: Faculty Rank

Professor Emeritus
sort order: 8
type: Faculty Rank

Assistant Professor
sort order: 13
type: Faculty Rank

Associate Professor
sort order: 10
type: Faculty Rank

Chair And Professor
sort order: 4
type: Faculty Rank

Professor
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position in department: Medicine
position in division: Endocrinology & Diabetes
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Health System Science
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Genetic and Cellular Medicine
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Cardiovascular Medicine
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Genetic and Cellular Medicine
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Professor
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position in department: Molecular, Cell and Cancer Biology
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: RNA Therapeutics Institute
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Shin, Dong-Soo
first name: Dong-Soo
last name: Shin
full name: Dong-Soo Shin PhD, RN
has faculty rank: ADJUNCT PROFESSOR
Person ID: 10248397
person in primary position: Adjunct Professor
type: Agent
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preferred title: Adjunct Professor

Professor
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position in department: Program in Molecular Medicine
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Molecular, Cell and Cancer Biology
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Medicine at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Chair and Professor
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position in department: Genetic and Cellular Medicine
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sort order: 1
type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Professor Emeritus
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position in department: Biochemistry and Molecular Biotechnology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Associate Professor
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position in department: Medicine
position in division: Geriatrics
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School