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Professor
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position in department: Medicine
position in division: Hematology/Oncology
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HR job title: Professor
position in organization: UMass Chan Medical School

Karlsson, Elinor
first name: Elinor
last name: Karlsson
full name: Elinor Kathryn Karlsson PhD
has faculty rank: Associate Professor
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Person ID: 4050
person in primary position: Associate Professor
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type: Person
Endowed Chair Honorary Title: Dr. Eileen L. Berman and Stanley I. Berman Foundation Chair in Biomedical Research
Lab URL: http://karlssonlab.org
preferred title: Associate Professor

Molecular, Cell and Cancer Biology
type: Department
type: Organization

School of Public Health and Health Sciences
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type: Organization

Medicine
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Neurology
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Pediatrics
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Program in Molecular Medicine
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Radiology
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Surgery
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Systems Biology
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Information Technology
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College of Natural Sciences
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Cardiovascular Medicine
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Epidemiology
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Food Science
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Vet & Animal Sciences
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Veterinary & Animal Sciences
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Gastroenterology
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Geriatrics
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Health Informatics And Implementation Science
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Hematology/Oncology
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Biostatistics And Health Services Research
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Rheumatology
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Vascular Surgery
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Biostatistics And Epidemiology
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UMass Chan Medical School
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University of Massachusetts Amherst
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Messina, Louis
first name: Louis
last name: Messina
full name: Louis M Messina MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 1058
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Johnnie Ray Cox Term Chair in Biomedical Research
preferred title: Professor

Rando, Oliver
first name: Oliver
last name: Rando
full name: Oliver J Rando MD, PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 1067
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Endowed Chair in Biochemistry and Molecular Biotechnology II
Post Docs: For more information about the Postdoctoral position in Dr. Rando’s lab please use the link provided. Post doc position
Rotation Projects: Rotation projects are available to study chromatin structure and function. Project 1. Measure histone dynamics in yeast. Histone dynamics play major roles in chromatin metabolism and in the inheritance of chromatin states. To measure histone replacement rates in yeast, we have created yeast strains carrying inducible epitope-tagged histones H3 and H2A. Using microarrays, we will measure histone replacement rates in a variety of mutant yeast to ascertain the role of various chromatin remodeling factors in histone exchange reactions. Project 2. Characterize mechanisms for epigenetic inheritance in yeast. We have identified a variety of genes whose expression state in yeast is epigenetically heritable. We will screen the yeast genome for genes that affect the inheritance of these expression patterns. Project 3. Measure histone dynamics in embryonic stem cells. Embryonic stem cells are pluripotent cells that can give rise to every type of cell in the adult animal. The role of chromatin structure in maintaining this pluripotent state is poorly understood, but it appears that stem cell chromatin is exceptionally labile relative to that in differentiated cells. We will create stem cell lines with inducible tagged histones to measure histone replacement rates across the mouse genome.
preferred title: Professor

Flotte, Terence
first name: Terence
last name: Flotte
full name: Terence R Flotte MD
has faculty rank: Professor
latitude: 42.27721310000000
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Person ID: 1094
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Elisabeth Chair for the Dean of Medicine
preferred title: Professor

Schanzer, Andres
first name: Andres
last name: Schanzer
full name: Andres Schanzer MD
has faculty rank: Professor
latitude: 42.27525000000000
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Person ID: 1104
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Cutler Chair in Vascular and Endovascular Surgery
preferred title: Professor

Kelliher, Michelle
first name: Michelle
last name: Kelliher
full name: Michelle A Kelliher PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 115
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Our Danny Cancer Fund Chair in Biomedical Research I
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Kelliher for additional details.
Rotation Projects: Please visit the Kelliher Lab website at: http://labs.umassmed.edu/kelliherlab/ to learn more about our current research areas. 1. Identify genes/pathways that mediate leukemia-initiating cell survival 2. Understand the molecular basis of glucocorticoid resistance in leukemia 3. Examine contribution of RIPK1 kinase in inflammatory and autoimmune disease mouse models. 4. Reveal tissue-specific roles for RIPK1 in cell death and inflammation. Use conditional Ripk1 allele to investigate effects of Ripk1 deletion in liver, pancreas and antigen presenting cells.
preferred title: Professor

Weng, Zhiping
first name: Zhiping
last name: Weng
full name: Zhiping Weng PhD
has faculty rank: Chair And Professor
latitude: 42.27985300000000
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Person ID: 1152
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Li Weibo Chair in Biomedical Research
Post Docs: The project aims to develop computational algorithms and software programs for analyzing high-throughput sequence data such as ChIP-Seq RNA-Seq small RNA sequencing data. PhD required. A strong background in computational biology especially experience with analyzing high-throughput sequencing data is highly desirable. Excellent communication and writing skills and the ability to work with experimental and computational collaborators are essential. To apply please forward CV cover letter and three references to: Zhiping.Weng@umassmed.edu
Rotation Projects: Please contact Dr. Weng for information on rotations that are available in her lab.
preferred title: Chair and Professor

Kiefe, Catarina
first name: Catarina
last name: Kiefe
full name: Catarina I Kiefe PhD, MD
has faculty rank: Professor
latitude: 42.27767280000000
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Person ID: 1282
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Melvin S. and Sandra L. Cutler Chair in Biomedical Research
preferred title: Professor

Bailey, Jeffrey
first name: Jeffrey
last name: Bailey
full name: Jeffrey A Bailey MD, PhD
has faculty rank: ADJUNCT ASSOCIATE PROFESSOR
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 1283
person in primary position: Adjunct Associate Professor
type: Agent
type: Person
Post Docs: The lab is currently looking for motivated postdoctoral scholars with backgrounds in genomics and computational biology. Please email the PI.
Rotation Projects: Rotation projects are available related to malaria and Burkitt lymphoma. Our projects range from genetic epidemiology to directed genomics studying human, parasite and tumor.
preferred title: Adjunct Associate Professor
webpage: https://profiles.umassmed.edu/profile/28866617

Ware, John
first name: John
last name: Ware
full name: John E Ware PhD
has faculty rank: Professor Emeritus
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 1336
person in primary position: Professor Emeritus
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type: Person
preferred title: Professor Emeritus

Barton, Bruce
first name: Bruce
last name: Barton
full name: Bruce A Barton PhD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 1371
person in primary position: Professor
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preferred title: Professor

Shultz, Leonard
first name: Leonard
last name: Shultz
full name: Leonard Donald Shultz PhD
has faculty rank: Professor
latitude: 44.36637960000000
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Person ID: 2863
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Zierath, Juleen
first name: Juleen
last name: Zierath
full name: Juleen R Zierath PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27587600000000
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Person ID: 3151
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Lapane, Kate
first name: Kate
last name: Lapane
full name: Kate L Lapane PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
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Person ID: 3252
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Puri, Ajit
first name: Ajit
last name: Puri
full name: Ajit Singh Puri MD, DM, DMRE
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
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Person ID: 3253
person in primary position: Professor
type: Agent
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preferred title: Professor

Henninger, Nils
first name: Nils
last name: Henninger
email address: w8ip9dqS9xWMQqXDzAY0dVS+h24VZ+hbL+eK
full name: Nils Henninger MD, PhD
has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 3265
person in primary position: Associate Professor
type: Agent
type: Person
Summary: Dr. Henninger is a vascular neurologist with research interest in the neurobiology of axonal injury associated with traumatic brain injury and its contribution to functional outcome.
preferred title: Associate Professor

Heneka, Michael
first name: Michael
last name: Heneka
full name: Michael Thomas Heneka MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 50.70274210000000
longitude: 7.10034010000000
Person ID: 3432
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Harrold, Leslie
first name: Leslie
last name: Harrold
full name: Leslie R Harrold MD, MPH
has faculty rank: Associate Professor
latitude: 42.27767280000000
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Person ID: 357
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Chasan-Taber, Lisa
first name: Lisa
last name: Chasan-Taber
full name: Lisa Chasan-Taber MPH, ScD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3699
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Bertone-Johnson, Elizabeth
first name: Elizabeth
last name: Bertone-Johnson
full name: Elizabeth R Bertone-Johnson ScD SM
has faculty rank: Associate Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3724
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Osborne, Barbara
first name: Barbara
last name: Osborne
full name: Barbara A Osborne PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3725
person in primary position: MCB Director
type: Agent
type: Person
preferred title: MCB Director

Minter, Lisa
first name: Lisa
last name: Minter
full name: Lisa M Minter BS, PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3753
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Pederson, Thoru
first name: Thoru
last name: Pederson
full name: Thoru Pederson PhD
has faculty rank: Professor Emeritus
latitude: 42.28050130000000
longitude: -71.76534550000000
Person ID: 379
person in primary position: Professor Emeritus
type: Agent
type: Person
Endowed Chair Honorary Title: Vitold Arnett Professor of Cell Biology
Rotation Projects: Background for Student Rotation Projects <p >See Politz, Hogan and Pederson (2009) and Politz et al. (2005) in the above list. The novel microRNA work may be the most suitable for student rotations. Potential Rotation Projects <p >Are the nucleolar microRNAs pri-, pre- or mature? <p >Are they complexed with other nucleolar RNAs? <p >Do the cell cycle related proteins in the nucleolus exist as heterotypic complexes? <p >Does the nucleolus of human embryonic stem cells also share these features (which we have so far looked for, and found, only in transformed human cell lines)? <p >Can vanadium tagging be used to detect specific proteins by electron microscopy, perhaps exceeding the limitations of immuno-EM?
preferred title: Professor Emeritus

Xiao, Hang
first name: Hang
last name: Xiao
full name: Hang Xiao PhD
has faculty rank: Associate Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3795
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Wolf, Greg
first name: Greg
last name: Wolf
Twitter: https://profiles.umassmed.edu/profile/28867023
full name: Greg Wolf
has faculty rank: Other
latitude: 42.28346030000000
longitude: -71.72665900000000
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Person ID: 3864
person in primary position: Chief Information Officer
type: Agent
type: Person
preferred title: Chief Information Officer
webpage: https://profiles.umassmed.edu/profile/28866533

Rogaev, Evgeny
first name: Evgeny
last name: Rogaev
full name: Evgeny I Rogaev PhD
has faculty rank: Professor
latitude: 42.27380970000000
longitude: -71.76834340000000
Person ID: 39
person in primary position: Professor
type: Agent
type: Person
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Rogaev for additional details.
preferred title: Professor

Houghton, Jeanmarie
first name: Jeanmarie
last name: Houghton
full name: Jeanmarie Houghton MD, PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
Person ID: 457
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Brehm, Michael
first name: Michael
last name: Brehm
full name: Michael A Brehm PhD
has faculty rank: Professor
latitude: 42.27694690000000
longitude: -71.76568470000000
Person ID: 474
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Harvey A. Shultz Chair in Diabetes
preferred title: Professor

Wolfe, Scot
first name: Scot
last name: Wolfe
full name: Scot Wolfe PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 595
person in primary position: Professor
type: Agent
type: Person
Post Docs: Postdoctoral Fellow Applications are being accepted for one position. A position is available to develop Cys2His2 zinc finger proteins (ZFPs) for the treatment of monogenic disorders. This project will focus on the creation of ZFPs with novel DNA-binding specificity to recognize sequence elements within genomic loci of therapeutic interest. In collaboration with other laboratories, we will evaluate the activity of these ZFP-based gene therapy reagents in vitro and in vivo in relevant disease models. Applicants will also have the opportunity to learn to apply Cas9 and Cas12a editing systems in vivo.
Rotation Projects: Potential Rotation Projects Improving the Precision of CRISPR/Cas9 nucleases for gene therapy applications: We are working to improve the precision of the CRISPR/Cas9 system to generate nucleases that will cleave at only a single site in the genome. These engineering efforts focus on increasing the DNA-editing precision of Cas9 and using protein engineering to introduce new properties into the nuclease. Much of this work is now transitioning to the use of Cas9 (and Cas12a) protein-RNA complexes. These modified nucleases will then be applied to patient derived cell-culture systems for the targeted repair or inactivation of disease-causing alleles. With the eventual goal of creating therapeutics for Sickle Cell Disease, beta-Thalassemia, HIV, Limb Girdle Muscular Dystrophy, Hermansky Pudlak Syndrome and other monogenic disorders. ex vivo genome editing in CD34+ HSPCs: We are developing improved Cas9 proteins for delivery ex vivo into CD34+ HSPCs for therapeutic application to sickle cell disease and beta-thalassemia. The goal is to modify the hematopoietic stem cells of a patient to complement the loss of function of the beta-globin gene and then return these cells to the patient through an autologous transplant. Development of Cys2His2 Zinc fingers proteins (ZFPs) as targeted therapeutics: We are developing artificial ZFPs for the regulation of target genes to change their gene expression profiles for therapeutic applications.
preferred title: Professor

Greiner, Dale
first name: Dale
last name: Greiner
full name: Dale L Greiner PhD
has faculty rank: Professor
latitude: 42.27913100000000
longitude: -71.76550320000000
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Person ID: 612
person in primary position: Professor
type: Agent
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Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
preferred title: Professor

Dekker, Job
first name: Job
last name: Dekker
full name: Job Dekker PhD
has faculty rank: Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 759
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Joseph J. Byrne Chair in Biomedical Research
Rotation Projects: ? Rotation Projects Multiple rotation projects are available in several areas related to long-range gene regulation and higher order chromosome organization. Projects include thorough analyses of the biochemical mechanisms of long-range gene regulation of specific disease-related genes, as well as large-scale analyses of chromosome organization using high-throughput genomics technologies (5C and Hi-C). The lab employs a wide range of experimental approaches, including cell culture, protein biochemistry, microscopy, genomics as well computational approaches such as bioinformatics and modeling. Specific rotation projects are determined dependent on the interest of the student.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866525
webpage: https://profiles.umassmed.edu/profile/28866572

Cerny, Jan
first name: Jan
last name: Cerny
full name: Jan Cerny MD, PhD
has faculty rank: Professor
latitude: 42.27525000000000
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Person ID: 777
person in primary position: Professor
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Goldberg, Robert
first name: Robert
last name: Goldberg
full name: Robert Joel Goldberg PhD
has faculty rank: Professor Emeritus
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Person ID: 78
person in primary position: Professor Emeritus
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preferred title: Professor Emeritus

Shaw, Leslie
first name: Leslie
last name: Shaw
full name: Leslie M Shaw PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 900
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webpage: https://profiles.umassmed.edu/profile/28866558

McManus, David
first name: David
last name: McManus
full name: David D McManus MD
has faculty rank: Chair And Professor
latitude: 42.27525000000000
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Person ID: 994
person in primary position: Chair and Professor
type: Agent
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Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
preferred title: Chair and Professor

Pediatric Genetics
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Friedmann, Peter
first name: Peter
last name: Friedmann
full name: Peter D Friedmann MD, MPH, DFASAM, FACP
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Person ID: 4333
person in primary position: Professor
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UMass Chan – Baystate Regional Campus
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Professor
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position in organization: University of Massachusetts Amherst

Associate Professor
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position in department: College of Natural Sciences
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position in organization: University of Massachusetts Amherst

Associate Professor
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HR job title: Associate Professor
position in organization: University of Massachusetts Amherst

MCB Director
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HR job title: MCB Director
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Professor
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Walkey, Allan
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Servais, Elliot
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McAlindon, Timothy
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Krings, Timo
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Maron, Martin
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Maron, Barry
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Shin, Dong-Soo
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person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Watkins, Ammara
first name: Ammara
last name: Watkins
full name: Ammara Abbasi Watkins MD, MPH
has faculty rank: Assistant Professor
Person ID: 10248403
person in primary position: Assistant Professor
type: Agent
type: Person
preferred title: Assistant Professor

Professor
is primary position: true
position in department: Program in Molecular Medicine
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Associate Professor
is primary position: true
position in department: Medicine at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Radiology at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor Emeritus
is primary position: true
position in department: Biochemistry and Molecular Biotechnology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

https://profiles.umassmed.edu/profile/88314388
publication date: 2025
type: URLLink
label: https://www.onclive.com/view/ihc-testing-may-enable-expedited-identification-of-tp53-mutant-mds-and-aml
link anchor text: OncLive with Dr. Patel and Dr. Gerber: p53 Immunohistochemistry

https://profiles.umassmed.edu/profile/89429665
publication date: 2025
type: URLLink
label: https://www.onclive.com/view/dr-patel-on-the-p53-ihc-positivity-as-potential-surrogate-for-multi-hit-tp53-mutations-in-mds-and-aml
link anchor text: Early Identification of TP53-Mutant MDS and AML Using p53 Immunostaining

https://profiles.umassmed.edu/profile/89429727
publication date: 2023
type: URLLink
label: https://journals.lww.com/oncology-times/blog/onlinefirst/pages/post.aspx
link anchor text: Point-of-Care p53 IHC Unveils TP53-Mutant MDS/AML

https://profiles.umassmed.edu/profile/89429786
publication date: 2025
type: URLLink
label: https://trial.medpath.com/news/61960d9f316e3daa/ihc-testing-enables-rapid-tp53-mutation-detection-in
link anchor text: IHC Enables Rapid Identification of TP53-Mutant MDS/AML

Chair and Associate Professor
is primary position: true
position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Chair and Associate Professor
position in organization: UMass Chan Medical School

Adjunct Associate Professor
is primary position: true
position in department: Medicine
position in division: Infectious Diseases
sort order: 1
type: Position
HR job title: Adjunct Associate Professor
position in organization: UMass Chan Medical School

https://profiles.umassmed.edu/profile/95558627
publication date: 2025
type: URLLink
label: https://ashpublications.org/ashclinicalnews/news/8743/p53-IHC-Testing-May-Be-Reliable-Surrogate-for
link anchor text: ASH Clinical News: p53 Immunohistochemistry for TP53-Mutant MDS/AML

Adjunct Professor
is primary position: true
position in department: Pediatrics
position in division: Pediatric Genetics
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

https://profiles.umassmed.edu/profile/99769701
publication date: 2025
type: URLLink
label: https://journals.lww.com/oncology-times/fulltext/2025/11000/immunostaining_offers_shortcut_to_detect_high_risk.20.aspx
link anchor text: p53 Immunostain in TP53-Mutant MDS and AML