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Molecular, Cell and Cancer Biology
type: Department
type: Organization

Family Medicine and Community Health
type: Department
type: Organization

Medicine
type: Department
type: Organization

Neurology
type: Department
type: Organization

Pathology
type: Department
type: Organization

Program in Molecular Medicine
type: Department
type: Organization

Radiology
type: Department
type: Organization

RNA Therapeutics Institute
type: Department
type: Organization

Surgery
type: Department
type: Organization

Work Environment
type: Department
type: Organization

College of Natural Sciences
type: Department
type: Organization

Chemistry
type: Division
type: Organization

Department of Food Science
type: Division
type: Organization

Food Science
type: Division
type: Organization

Gastroenterology
type: Division
type: Organization

Plastic Surgery
type: Division
type: Organization

Renal Medicine
type: Division
type: Organization

Biostatistics And Health Services Research
type: Division
type: Organization

Surgical Oncology
type: Division
type: Organization

Vascular Surgery
type: Division
type: Organization

School of Health And Environment
type: Division
type: Organization

UMass Chan Medical School
type: Organization

University of Massachusetts Lowell
type: Organization

University of Massachusetts Amherst
type: Organization

Mello, Craig
first name: Craig
last name: Mello
full name: Craig Mello PhD
has faculty rank: Distinguished Professor
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 1009
person in primary position: Distinguished Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Blais University Chair in Molecular Medicine
Rotation Projects: Potential Rotation Projects: There are numerous potential rotation project available in the Mello lab: Projects include: Investigation of RNAi and related mechanisms, including Piwi Argonaute pathways and their affects on fertility and epigenetic inheritance; Investigation of germline determination and cell-fate specification during embryogenesis; the exploration of CRISPR mediated genome editing tools for C. elegans and other organisms; and finally the use of CRISPR to generate C. elegans models for human genetic disease.
preferred title: Distinguished Professor
webpage: https://profiles.umassmed.edu/profile/28866500

Messina, Louis
first name: Louis
last name: Messina
full name: Louis M Messina MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 1058
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Johnnie Ray Cox Term Chair in Biomedical Research
preferred title: Professor

Flotte, Terence
first name: Terence
last name: Flotte
full name: Terence R Flotte MD
has faculty rank: Professor
latitude: 42.27721310000000
longitude: -71.76076230000000
Person ID: 1094
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Elisabeth Chair for the Dean of Medicine
preferred title: Professor

Schanzer, Andres
first name: Andres
last name: Schanzer
full name: Andres Schanzer MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 1104
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Cutler Chair in Vascular and Endovascular Surgery
preferred title: Professor

McCormick, Beth
first name: Beth
last name: McCormick
full name: Beth A McCormick PhD
has faculty rank: Chair And Professor
latitude: 42.27719870000000
longitude: -71.75921810000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1237
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Worcester Foundation for Biomedical Research Chair II
Lab URL: https://www.umassmed.edu/mccormicklab/
Summary: Focus: Mucosal inflammation, host: pathogen interactions, and cancer biology
preferred title: Chair and Professor

Harlan, David
first name: David
last name: Harlan
full name: David M Harlan MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1355
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: William and Doris Krupp Professor in Medicine
preferred title: Professor

Swain, Susan
first name: Susan
last name: Swain
full name: Susan L Swain PhD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 1360
person in primary position: Professor
type: Agent
type: Person
Post Docs: An entry level postdoctoral position is open immediately in the laboratory of Dr. Susan L. Swain to study the factors that control the development and survival of CD4 and CD8 T cell memory. Graduate student experience with tissue culture, in vitro assay, flow cytometry, experience in mouse models on infectious disease and a knowledge of cellular and molecular immunology are all strongly desired.
Rotation Projects: <p >Rotations: Projects in the following areas <p >CD4 T cell memory. We can generate in vitro CD4 T cells that are for all extents and purposes identical to the memory CD4 T cells observed in vivo. In situ memory CD4 T cells persist at very low frequency and in most instances it is difficult to analyze them thoroughly using tetramer or multimer reagents both because of their low frequency and the relatively low specific affinity of the Class II reagents for the TcR. Being able to generate “recent” memory cells in vitro gives us the opportunity to analyze in detail the mechanisms by which memory CD4 T cells may contribute to secondary immunity and immune protection. Once identified. will determine if particular pathways are relevant in situ. We have discovered that memory CD4 T cells are superior in protection to those from the primary response and that they display pleitropic functions that have not been previously identified. <p > Cytotoxic CD4 Effectors. One unexpected function of CD4 T cells we identified is robust, perforin-dependent cytotoxic activity (7, 16). Cytotoxic activity by CD4 T cells has been reported in response to several infections, but its significance has not heretofore been established. We find that “Th1 polarized” CD4 effectors and more relevantly the CD4 effectors found in the lung following influenza infection, are able to kill infected or peptide-pulsed Class II-bearing targets and we find that this perforin dependent activity can work together with antibody to provide protection against lethal influenza challenge in otherwise unprimed mice (17). We also will determine when memory CD4 T cells re-express cytotoxic activity following in vivo challenge and how cytotoxic killing contributes to the memory cell mediated protection. We want to analyze how the program of cytotoxicity is induced in these “ThCTL”. <p > Memory CD4 Cells Enhance an Innate Response. Memory cells can act by becoming secondary effectors but they are best characterized by …
preferred title: Professor

Barton, Bruce
first name: Bruce
last name: Barton
full name: Bruce A Barton PhD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1371
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Kent, Sally
first name: Sally
last name: Kent
full name: Sally C Kent PhD
has faculty rank: Associate Professor
latitude: 42.27714780000000
longitude: -71.76564580000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1405
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Latz, Eicke
first name: Eicke
last name: Latz
full name: Eicke Latz MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27985300000000
longitude: -71.79190270000000
Person ID: 153
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Fain, James
first name: James
last name: Fain
full name: James Allen Fain PhD, RN, BC-ADM, FAAN
has faculty rank: Professor
latitude: 42.27721310000000
longitude: -71.76076230000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 1881
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Fitzgerald, Katherine
first name: Katherine
last name: Fitzgerald
full name: Katherine A Fitzgerald PhD
has faculty rank: Professor
latitude: 42.27985300000000
longitude: -71.79190270000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 202
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Worcester Foundation for Biomedical Research Chair III
Rotation Projects: Please email Kate.Fitzgerald@umassmed.edu if you are interested in rotations.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866427
webpage: https://profiles.umassmed.edu/profile/28866493

Mazor, Kathleen
first name: Kathleen
last name: Mazor
full name: Kathleen Mazor EdD
has faculty rank: Professor Emeritus
latitude: 42.29218100000000
longitude: -71.76031190000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 217
person in primary position: Professor Emeritus
type: Agent
type: Person
preferred title: Professor Emeritus

Serreze, David
first name: David
last name: Serreze
full name: David V Serreze PhD
has faculty rank: Associate Professor
latitude: 44.36637960000000
longitude: -68.19692870000000
Person ID: 2838
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Shultz, Leonard
first name: Leonard
last name: Shultz
full name: Leonard Donald Shultz PhD
has faculty rank: Professor
latitude: 44.36637960000000
longitude: -68.19692870000000
Person ID: 2863
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Czech, Michael
first name: Michael
last name: Czech
full name: Michael Paul Czech PhD
has faculty rank: Professor Emeritus
latitude: 42.27913450000000
longitude: -71.76550630000000
Person ID: 289
person in primary position: Professor Emeritus
type: Agent
type: Person
Endowed Chair Honorary Title: Isadore and Fannie Foxman Chair in Medical Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Czech for additional details.
Rotation Projects: Mentoring……………………………………………………………………………………………………… The Czech laboratory is active in mentoring graduate students and postdoctoral fellows. Many former student and postdoctoral trainees of the Czech laboratory are now internationally recognized professors at major universities and medical schools. These former lab members include: Paul Pilch, Professor of Biochemistry, Boston University School of Medicine Jeffrey Pessin, Professor and Director of the Diabetes Center, Einstein College of Medicine Joan Massague, Director, Sloan Kettering Institute Roger Davis, HHMI investigator and Professor of Molecular Medicine, UMASS Medical School Silvia Corvera, Professor of Molecular Medicine, Co-Director of the MD/PhD Program, UMASS Medical School Carla Greenbaum, Vice Chair and Director of Clinical Research, Benaroya Research Institute Jes Klarlund, Professor of Ophthalmology, University of Pittsburgh Medical Center Rob Lewis, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Richard MacDonald, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Assia Shisheva, Professor of Physiology, Wayne State School of Medicine. Mark Sleeman, Professor of Physiology, Monash University, Australia John Harris, Associate Professor of Medicine, UMASS Medical School Zhen Jiang, Associate Professor of Pharmacology and Medicine, Boston University Vishu Puri, Professor of Biomedical Sciences, Ohio University Olga Gupta, Assistant Professor of Pediatrics and Medicine, University of Texas Southwestern Medical Center Tim Fitzgibbons, Assistant Professor of Medicine, UMASS Medical School Myriam Aouadi, Assistant Professor, Integrated Cardio Metabolic Centre, Karolinska Institute Adilson Guilherme, Associate Professor, University of Massachusetts Medical School Our laboratory currently offers graduate student Rotation Projects (examples below and others available) and Thesis Research …
preferred title: Professor Emeritus

Mordes, John
first name: John
last name: Mordes
full name: John P Mordes MD
has faculty rank: Professor Emeritus
latitude: 42.27636250000000
longitude: -71.76564740000000
Person ID: 305
person in primary position: Professor Emeritus
type: Agent
type: Person
preferred title: Professor Emeritus

Theurkauf, William
first name: William
last name: Theurkauf
full name: William E Theurkauf PhD
has faculty rank: Professor
latitude: 42.27694690000000
longitude: -71.76568470000000
Person ID: 306
person in primary position: Professor
type: Agent
type: Person
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Theurkauf for additional details.
Rotation Projects: Rotation Projects Proper control of cell division and accurate chromosome segregation are fundamental to cell function and normal development. Chromosome segregation errors lead to birth defects, and abnormal cell division control is associated with essentially all cancers. A major aim of research in the laboratory is to understand cell cycle control and chromosome segregation mechanisms. We use a combination of classical and molecular genetics, high-resolution in vivo imaging, and biochemical techniques to define pathways that control the cell cycle and chromosome segregation in response to environmental insult (DNA damaging agents) and developmental queues. Rotation projects focus on the role of cell cycle checkpoint and tumor suppressor pathways during the earliest stages of embryogenesis, and cell cycle control of actin and microtubule reorganization during mitosis. Through these projects, students gain exposure of the art in vivo imaging and genetic and molecular manipulations of gene function to define pathways controlling cell division and chromosome segregation. Embryonic Patterning Essentially all cells are asymmetric, with structurally distinct surfaces and polarized internal organization. This asymmetry is essential to the specialized functions cells serve within complex multi-cellular organisms . A second area of interest focuses on the mechanisms that establish cellular asymmetry. In Drosophila, the embryonic axes are specified during oogenesis through the asymmetric localization of key morphogenetic molecules within the developing oocyte. We use axis specification in the fly as a model for the processes that establish cellular asymmetry. An intact microtubule network is essential to axis specification in the fly oocyte and to polarization of somatic. We hope to define the molecular functions for microtubules in establishing cellular asymmetry. We are currently using in vivo imaging techniques to directly characterize the microtubule dependent mRNA tran…
preferred title: Professor

Zierath, Juleen
first name: Juleen
last name: Zierath
full name: Juleen R Zierath PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27587600000000
longitude: -71.76211600000000
Person ID: 3151
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

DeBenedectis, Carolynn
first name: Carolynn
last name: DeBenedectis
full name: Carolynn Michelle DeBenedectis MD
has faculty rank: Professor
latitude: 42.33637660000000
longitude: -71.10713790000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 3251
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

LaFemina, Jennifer
first name: Jennifer
last name: LaFemina
full name: Jennifer LaFemina MD
has faculty rank: Professor
latitude: 42.27525450000000
longitude: -71.76235130000000
Person ID: 3286
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Aiello, Francesco
first name: Francesco
last name: Aiello
full name: Francesco Anthony Aiello MD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 3288
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Rock, Kenneth
first name: Kenneth
last name: Rock
full name: Kenneth L Rock MD
has faculty rank: Chair And Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 332
person in primary position: Chair and Professor
type: Agent
type: Person
Endowed Chair Honorary Title: UMass Chan Medical School Chair in Biomedical Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Rock for additional details.
Rotation Projects: Potential Rotation Projects <p >Rotations are available in Dr. Rock’s laboratory for graduate students in the GSBS program. The rotation projects will explore various aspects of how the immune system carries out surveillance to detect viral infections and cancers. Among the potential areas of research are: (1) The alarm signals that alert the immune system to potential danger; (2) The initial innate immune and inflammatory response to infection or other dangerous situations; (3) The biology of the sentinel cells (e.g. dendritic cells) that sense danger and report it the adaptive immune system; (4) The mechanisms by which sentinel cells (e.g. dendritic cells) acquire and display antigens to T cells; and, (5) The antigen presentation pathways by which virally infected or cancer cells display a sampling of their expressed gene products to the activated T cells. Specific rotation projects are chosen based on the student’s interests and state/availability of the various projects in the laboratory. The goals of rotations are for the student to gain knowledge in immunology, to learn how to approach experimental problems, to learn new techniques and methods, and to actually generate data that moves our knowledge forward. In addition, the rotation provides the student the opportunity to evaluate the laboratory as a possible place to conduct their thesis research in the future.
preferred title: Chair and Professor

Khvorova, Anastasia
first name: Anastasia
last name: Khvorova
full name: Anastasia Khvorova PhD
has faculty rank: Professor
latitude: 42.27767280000000
longitude: -71.76163720000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 3413
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Remondi Family Chair in Biomedical Research
Post Docs: POSTDOCTORAL POSITION: RNAI PRECLINICAL DEVELOPMENT Excellent training opportunity for a person considering industrial carrier in drug development Oligonucleotides represent a new class of drugs, which have the promise to become a major class of future therapeutics. There are several classes of oligonucleotides which can efficiently silence genes in various tissues with acceptable level of toxicity. There are also new chemistries being developed to further improve oligonucleotide tissue distribution and cellular uptake. The successful candidate will be a key part of an intra-disciplinary team working with biologists and chemists to develop novel types of therapeutics for treatment of neurological disease, liver disease and orphan indications. The work will include compounds identification, screening, characterization, in vivo efficacy and PK/PD studies, novel assays development etc. In addition exposure and training in nucleic acid pre-clinical development, project management etc will be provided. QUALIFICATIONS: Applicants must have (or expect to obtain shortly) a Ph.D. in Chemistry, Organic Chemistry Biochemistry, Cell Biology, Molecular Biology or a related field , be bright, ambitious, independent and collaborative and ideally, have research experience in nucleic acid molecular cell biology or pharmacology.
Post Docs: RNAI MEDICINAL CHEMISTRY/ RNA OLIGONUCLEOTIDE CHEMISTRY Develop and characterize novel RNA chemistries to promote efficient oligonucleotide internalization and tissue distribution. Oligonucleotides represent a new class of drugs, which have the promise to become a major class of future therapeutics. There are several chemistries and formulations developed by us and others that effectively support oligo internalization and favorable PK/PD. In most cases in vivo efficacy is limited by (1) poor PK (2) inefficient tissue distribution (3) compound entrapment in biologically inactive intracellular compartments. The objective of future studies will be development of novel chemistries, which promote receptor mediated cellular internalization and/ or endosomal escape. The successful candidate will be responsible for the design and synthesis of novel RNA precursors, optimization of RNA synthesis and conjugation protocols and interface with the biology part of the lab. In addition, exposure to pre-clinical development programs and oligonucleotide manufacturing will be available. QUALIFICATIONS: Applicants must have (or expect to obtain shortly) a Ph.D. in Chemistry, Organic Chemistry Biochemistry, Cell Biology, Molecular Biology or a related field , be bright, ambitious, independent and collaborative and have previous experience in nucleic acid / oligonucleotide chemistry.
Post Docs: SMALL RNA TRAFFICKING Discover, characterize and adapt mechanisms of small RNA extracellular and intracellular trafficking for development of novel classes of oligonucleotide drugs. A serious limitation in realizing the potential of oligonucleotide based therapies has been the exceedingly inefficient transit of oligonucleotides from outside cells to the intracellular compartments where the biologically relevant activity happens. On the other hand, there are multiple lines of evidence supporting the notion that nature has implemented evolutionarily conserved mechanisms and pathways for efficiently trafficking small RNAs across cellular boundaries. The objective of future studies will be the systematic evaluation of mechanisms of cellular uptake of different classes of oligonucleotides and their comparison to mechanisms of native RNA trafficking using a combination of experimental approaches, including advanced RNA chemistry and high temporal and spatial resolution microscopy in living cells, Mass spectrometry, cell biology and others. The successful candidate will work closely with Victor Ambros and Silvia Corvera labs and the UMASS imaging group and receive training in RNA chemistry, biochemistry, cell biology and pre-clinical development. QUALIFICATIONS:Applicants must have (or expect to obtain shortly) a Ph.D. in Chemistry, Organic Chemistry Biochemistry, Cell Biology, Molecular Biology or a related field , be bright, ambitious, independent and collaborative and ideally, have research experience in nucleic acid molecular and cell biology
Rotation Projects: Our laboratory uses a combination of nucleic acid and oligonucleotide chemistry, biochemistry, cell biology, and pharmacology and develops and evaluate novel technologies for development of oligonucleotide therapeutics. A rotation project is available to develop and identify chemically modified self-delivering RNAi compounds for treatment of Huntington and other diseases.
preferred title: Professor

Heneka, Michael
first name: Michael
last name: Heneka
full name: Michael Thomas Heneka MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 50.70274210000000
longitude: 7.10034010000000
Person ID: 3432
person in primary position: Adjunct Professor
type: Agent
type: Person
preferred title: Adjunct Professor

Bello, Dhimiter
first name: Dhimiter
last name: Bello
full name: Dhimiter Bello ScD, MSc
has faculty rank: Associate Professor
latitude: 42.64602850000000
longitude: -71.36462360000000
Person ID: 3522
person in primary position: https://profiles.umassmed.edu/profile/16236512
type: Agent
type: Person

Verma, Ashish
first name: Ashish
last name: Verma
full name: Ashish Verma MD, MRCP, FACP, FASN, FRCP
has faculty rank: Assistant Professor
latitude: 42.27767280000000
longitude: -71.76163720000000
Person ID: 3588
person in primary position: Assistant Professor
type: Agent
type: Person
preferred title: Assistant Professor

Szabo, Gyongyi
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo MD, PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27636250000000
longitude: -71.76564740000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 36
person in primary position: Adjunct Professor
type: Agent
type: Person
Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
preferred title: Adjunct Professor

Simons, Jessica
first name: Jessica
last name: Simons
full name: Jessica P Simons MD, MPH
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
Person ID: 3626
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Rotello, Vincent
first name: Vincent
last name: Rotello
full name: Vincent Rotello PhD
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3741
person in primary position: Department Head
type: Agent
type: Person
preferred title: Department Head

McClements, David
first name: David
last name: McClements
full name: David J McClements B.S., Ph.D.
has faculty rank: Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3760
person in primary position: Fergus Clydesdale Endowed Chair
type: Agent
type: Person
preferred title: Fergus Clydesdale Endowed Chair

Xiao, Hang
first name: Hang
last name: Xiao
full name: Hang Xiao PhD
has faculty rank: Associate Professor
latitude: 42.39565560000000
longitude: -72.52196170000000
Person ID: 3795
person in primary position: Associate Professor
type: Agent
type: Person
preferred title: Associate Professor

Lawrence, Jeanne
first name: Jeanne
last name: Lawrence
Featured Videos: https://profiles.umassmed.edu/profile/28867178
full name: Jeanne B Lawrence PhD
has faculty rank: Professor
latitude: 42.27525000000000
longitude: -71.76233800000000
photo: https://profiles.umassmed.edu/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 399
person in primary position: Professor
type: Agent
type: Person
Endowed Chair Honorary Title: Leo P. and Theresa M. LaChance Chair in Medical Research
Lab URL: https://www.umassmed.edu/lawrencelab
Summary: Lawrence lab research bridges fundamental questions of developmental epigenetics with translational research into the common problem of chromosome abnormalities, particularly Down syndrome.
preferred title: Professor

Zamore, Phillip
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Endowed Chair Honorary Title: Gretchen Stone Cook Chair in Biomedical Sciences
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Zamore for additional details
Rotation Projects: Potential Rotation Projects Our laboratory uses a combination of biochemistry, cell biology, and genetics to dissect the RNAi pathway. A rotation project is available to explore the mechanisms that underlie the RNAi phenomenon or the biological pathways in which RNAi enzymes participate in flies, mice and humans.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866555
webpage: https://profiles.umassmed.edu/profile/28866537
webpage: https://profiles.umassmed.edu/profile/28866541

Crawford, Sybil
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Brehm, Michael
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Endowed Chair Honorary Title: Harvey A. Shultz Chair in Diabetes
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Greiner, Dale
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Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
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Sullivan-Bolyai, Susan
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Han, Gang
first name: Gang
last name: Han
Twitter: https://profiles.umassmed.edu/profile/28867140
full name: Gang Han PhD
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Post Docs: Positions for postdoctoral fellows are available in the laboratory of Dr. Gang Han at the Department of Biochemistry and Molecular Pharmacology of The University of Massachusetts- Medical School. Research will focus on developing novel small molecule/ nanoparticle approaches for translational biomedical sciences and molecular imaging. Qualifications: Candidates have a Ph.D degree in (1)Organic Chemistry/polymer synthesis , (2) Molecular cell biology , (3) Biophysics or (4) Biochemistry. A solid training and substantial organic synthesis, animal experiments, spectroscopy and microscopy are desired. Candidates need to have strong work ethic, creativity, and enthusiasm with proven ability to work independently and collaboratively. To apply: Applicants should submit their CV including a full publication list and sources of three reference letters by email to gang.han@umassmed.edu
Rotation Projects: Rotation projects <p >(1) Specific cell membrane component labeling using bioconjugated nanoparticles <p >(2) To develop tools for targeted and traceable siRNA delivery <p >(3) To synthesize functional nanomaterials for detecting biomarkers in biological fluids
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Basadonna, Giacomo
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Wang, Jennifer
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Shaw, Leslie
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Mercurio, Arthur
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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
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Bogdanov, Alexei
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webpage: https://profiles.umassmed.edu/profile/28866578
webpage: https://profiles.umassmed.edu/profile/28866620

Watts, Jonathan
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Seymour, Neal
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Friedmann, Peter
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UMass Chan – Baystate Regional Campus
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Hogan, Susan
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https://profiles.umassmed.edu/profile/16236512
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Fergus Clydesdale Endowed Chair
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ADJUNCT PROFESSOR
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Organ Transplantation
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Population and Quantitative Health Sciences
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Neurological Surgery
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Giatsidis, Giorgio
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last name: Giatsidis
full name: Giorgio Giatsidis MD, PhD
has faculty rank: Assistant Professor
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Post Docs: Our team welcomes applications from individuals interested in advancing clinical care, science, and education through multidisciplinary innovation and research in restorative, regenerative, and global surgery. Positions are available for national and international undergraduate, graduate (including residents), and post-graduate students with a broad range of diverse expertise and backgrounds. Please submit your request along your CV to: giorgio.giatsidis@umassmed.edu Main areas of interest * Biological Sciences (wound healing & burns, tissue engineering, scaffolds, tissue mechanobiology, angiogenesis, lymphangiogenesis, tissue regeneration [skeletal muscle, adipose tissue, skin], scarring and fibrosis, aging, tissue allotransplantation) * Clinical Sciences (trials in plastic surgery [breast reconstruction, post-bariatric surgery, burns, chronic wounds, fat grafting], microsurgery, extremity trauma and replantation, aesthetic surgery/medicine) * Global Surgery & Advocacy * Surgical Education (design and evaluation of skill courses, simulation-based training, cadaver-based training, use of Augmented Reality and Virtual Reality in surgical education) * Biomedical Engineering (design and development of devices or technologies for wound care, tissue preservation, trauma care, surgical robotics, tissue imaging, and tissue diagnostics) * Software Engineering (mHealth applications in surgery, tele-surgery) * Art sciences (Medical illustrations)
Rotation Projects: Our team is committed to provide opportunities to UMMS students to both advance their education and produce scholarly work. Committment and goals are individually discussed and tailored based on the student's interests, goals, needs, and availability. Projects are commonly designed to be led by the student under guidance, and to result in a scientific publication authored by the student. For applications please contact: giorgio.giatsidis@umassmed.edu. Areas of specific interest include (but are not limited to): - Surgical Education - Global Surgery
preferred title: Assistant Professor
webpage: https://profiles.umassmed.edu/profile/28866414

Jones, Douglas
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Biochemistry and Molecular Biotechnology
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https://profiles.umassmed.edu/profile/28867140
ProfilesRNS Plugin Searchable Data: GangHan_UMMS

Surgery at UMass Chan - Baystate
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Sirianni, Rachael
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Wali, Ravinder
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Professor
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Professor
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Moffatt-Bruce, Susan
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Stain, Steven
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Medicine at UMass Chan - Lahey
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Surgery at UMass Chan - Lahey
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Professor Emeritus
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Nepomnayshy, Dmitry
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Associate Professor
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Professor
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Basic Pathology
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Breast Imaging
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Endocrinology & Diabetes
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Health System Science
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Infectious Diseases
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Innate Immunity
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Pulmonary Medicine
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Chandraker, Anil
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Endowed Chair Honorary Title: Jack M. Wilson Chair in Biomedical Research
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Professor
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Tan Chingfen Graduate School of Nursing
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Martinez, Fernando
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Professor
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Microbiology
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Maron, Barry
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Abelson, Jonathan
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Professor
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Professor
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Population and Quantitative Health Sciences
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Genetic and Cellular Medicine
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Genetic and Cellular Medicine
type: Department
type: Organization

Chair and Professor
is primary position: true
position in department: RNA Therapeutics Institute
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Distinguished Professor
is primary position: true
position in department: RNA Therapeutics Institute
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Distinguished Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: RNA Therapeutics Institute
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: RNA Therapeutics Institute
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Program in Molecular Medicine
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor Emeritus
is primary position: true
position in department: Radiology
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Associate Professor
is primary position: true
position in department: Medicine
position in division: Endocrinology & Diabetes
sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Indes, Jeffrey
first name: Jeffrey
last name: Indes
full name: Jeffrey E Indes MD, FACS
has faculty rank: Professor
Person ID: 10248490
person in primary position: Professor
type: Agent
type: Person
preferred title: Professor

Professor Emeritus
is primary position: true
position in department: Medicine
position in division: Endocrinology & Diabetes
sort order: 1
type: Position
HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Professor
is primary position: true
position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School