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Protein Transport
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Protein Phosphatase 1
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Combinatorial Chemistry Techniques
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DNA-Binding Proteins
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Cyclin-Dependent Kinase 6
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Antigens
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Humans
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Aged, 80 and over
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Prostatic Neoplasms
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HeLa Cells
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Genes, Tumor Suppressor
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Cell Nucleus
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S Phase
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COS Cells
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DNA Helicases
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Nitric Oxide
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p300-CBP Transcription Factors
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Retinoblastoma Protein
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Microarray Analysis
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Imidazoles
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Pyrazoles
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Fluorescent Antibody Technique
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Cell Survival
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Benzimidazoles
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Gonadal Steroid Hormones
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Down-Regulation
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Androgen Antagonists
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Treatment Outcome
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Protein Kinase Inhibitors
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Chromatin Immunoprecipitation
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Amino Acid Substitution
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Progesterone
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Animals
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Oncogene Proteins
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Carrier Proteins
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Aged
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Proto-Oncogene Proteins c-bcl-2
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Chromosomal Proteins, Non-Histone
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Cell Cycle Proteins
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Trans-Activators
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Amino Acid Sequence
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Two-Hybrid System Techniques
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Methylation
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CDC2 Protein Kinase
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Mice, Knockout
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Saccharomyces cerevisiae
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Cohort Studies
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Receptors, Retinoic Acid
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Antibodies
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MeSH semantic group name: Chemicals & Drugs
number of authors: 118
number of publications: 188
uniqueness weight: 0.925929
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Antineoplastic Agents
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MeSH semantic group name: Chemicals & Drugs
number of authors: 255
number of publications: 682
uniqueness weight: 0.669146
type: Concept

Pyrazines
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MeSH semantic group name: Chemicals & Drugs
number of authors: 29
number of publications: 37
uniqueness weight: 0.972547
type: Concept

Nuclear Proteins
MeSH DescriptorUI: D009687
MeSH semantic group name: Chemicals & Drugs
number of authors: 224
number of publications: 794
uniqueness weight: 0.705784
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Blotting, Western
MeSH DescriptorUI: D015153
MeSH semantic group name: Phenomena
MeSH semantic group name: Procedures
number of authors: 294
number of publications: 621
uniqueness weight: 0.893479
type: Concept

Bone Neoplasms
MeSH DescriptorUI: D001859
MeSH semantic group name: Disorders
number of authors: 60
number of publications: 129
uniqueness weight: 0.892512
type: Concept

Prostatic Hyperplasia
MeSH DescriptorUI: D011470
MeSH semantic group name: Disorders
number of authors: 16
number of publications: 35
uniqueness weight: 0.959768
type: Concept

Enhancer Elements, Genetic
MeSH DescriptorUI: D004742
MeSH semantic group name: Chemicals & Drugs
number of authors: 67
number of publications: 120
uniqueness weight: 0.931151
type: Concept

Genetic Predisposition to Disease
MeSH DescriptorUI: D020022
MeSH semantic group name: Physiology
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number of publications: 743
uniqueness weight: 0.73831
type: Concept

Pyrimidines
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MeSH semantic group name: Chemicals & Drugs
number of authors: 98
number of publications: 146
uniqueness weight: 0.924563
type: Concept

Jumonji Domain-Containing Histone Demethylases
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MeSH semantic group name: Chemicals & Drugs
number of authors: 15
number of publications: 19
uniqueness weight: 0.98715
type: Concept

Tumor Cells, Cultured
MeSH DescriptorUI: D014407
MeSH semantic group name: Anatomy
number of authors: 169
number of publications: 466
uniqueness weight: 0.929233
type: Concept

Mutant Proteins
MeSH DescriptorUI: D050505
MeSH semantic group name: Chemicals & Drugs
number of authors: 80
number of publications: 106
uniqueness weight: 0.954997
type: Concept

Prostate-Specific Antigen
MeSH DescriptorUI: D017430
MeSH semantic group name: Chemicals & Drugs
number of authors: 47
number of publications: 84
uniqueness weight: 0.955332
type: Concept

Chromatography, Liquid
MeSH DescriptorUI: D002853
MeSH semantic group name: Procedures
number of authors: 82
number of publications: 130
uniqueness weight: 0.955542
type: Concept

Up-Regulation
MeSH DescriptorUI: D015854
MeSH semantic group name: Physiology
number of authors: 214
number of publications: 379
uniqueness weight: 0.900468
type: Concept

Phenylthiohydantoin
MeSH DescriptorUI: D010669
MeSH semantic group name: Chemicals & Drugs
number of authors: 2
number of publications: 4
uniqueness weight: 0.999098
type: Concept

Chromatin
MeSH DescriptorUI: D002843
MeSH semantic group name: Anatomy
MeSH semantic group name: Chemicals & Drugs
MeSH semantic group name: Physiology
number of authors: 134
number of publications: 643
uniqueness weight: 0.693311
type: Concept

Feedback, Physiological
MeSH DescriptorUI: D025461
MeSH semantic group name: Phenomena
number of authors: 49
number of publications: 60
uniqueness weight: 0.968994
type: Concept

Mice
MeSH DescriptorUI: D051379
MeSH semantic group name: Living Beings
number of authors: 826
number of publications: 11215
uniqueness weight: 0.370155
type: Concept

Neoplastic Processes
MeSH DescriptorUI: D009385
MeSH semantic group name: Disorders
number of authors: 3
number of publications: 3
uniqueness weight: 0.998463
type: Concept

DNA Primers
MeSH DescriptorUI: D017931
MeSH semantic group name: Chemicals & Drugs
number of authors: 162
number of publications: 301
uniqueness weight: 0.943266
type: Concept

Cyclin-Dependent Kinase 4
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MeSH semantic group name: Chemicals & Drugs
number of authors: 14
number of publications: 18
uniqueness weight: 0.986037
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Genetic Variation
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MeSH semantic group name: Phenomena
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number of publications: 401
uniqueness weight: 0.828896
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Models, Biological
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MeSH semantic group name: Devices
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number of publications: 1217
uniqueness weight: 0.669928
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Proto-Oncogene Proteins c-mdm2
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 33
uniqueness weight: 0.980732
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Adenocarcinoma
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MeSH semantic group name: Disorders
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number of publications: 361
uniqueness weight: 0.780796
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Transcription, Genetic
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MeSH semantic group name: Physiology
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number of publications: 923
uniqueness weight: 0.72165
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Phosphotyrosine
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 25
uniqueness weight: 0.988891
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Neoplasms, Hormone-Dependent
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MeSH semantic group name: Disorders
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number of publications: 12
uniqueness weight: 0.994339
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Naphthoquinones
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 7
uniqueness weight: 0.996731
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E2F1 Transcription Factor
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 19
uniqueness weight: 0.984769
type: Concept

Mice, Inbred ICR
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MeSH semantic group name: Living Beings
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number of publications: 35
uniqueness weight: 0.991118
type: Concept

Pyridines
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 117
uniqueness weight: 0.920987
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Immediate-Early Proteins
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 46
uniqueness weight: 0.970276
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Lysine
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 93
uniqueness weight: 0.960387
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Cyclic GMP
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 33
uniqueness weight: 0.977541
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Proto-Oncogene Proteins c-akt
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 219
uniqueness weight: 0.893
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Enzyme Activation
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MeSH semantic group name: Physiology
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number of publications: 391
uniqueness weight: 0.924026
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Computational Biology
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MeSH semantic group name: Occupations
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number of publications: 364
uniqueness weight: 0.834257
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Male
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MeSH semantic group name: Physiology
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number of publications: 31073
uniqueness weight: 0.224534
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Prostate
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MeSH semantic group name: Anatomy
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number of publications: 122
uniqueness weight: 0.910011
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Mutation
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number of publications: 2679
uniqueness weight: 0.537024
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Consensus Sequence
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MeSH semantic group name: Concepts & Ideas
MeSH semantic group name: Genes & Molecular Sequences
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number of publications: 31
uniqueness weight: 0.993535
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Pyridones
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 43
uniqueness weight: 0.960293
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Cyclin-Dependent Kinase 9
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 8
uniqueness weight: 0.997431
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Mice, Transgenic
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Cytoplasm
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BRCA2 Protein
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number of publications: 19
uniqueness weight: 0.971971
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Receptor, Insulin
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 52
uniqueness weight: 0.972051
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Neoplasm Invasiveness
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number of publications: 287
uniqueness weight: 0.918766
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Drug Synergism
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uniqueness weight: 0.966479
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Antineoplastic Agents, Hormonal
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number of publications: 40
uniqueness weight: 0.963696
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Signal Transduction
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Female
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Xenograft Model Antitumor Assays
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RNA, Messenger
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Protein Structure, Secondary
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Cell Proliferation
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Time Factors
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BRCA1 Protein
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Membrane Transport Proteins
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Protein Structure, Tertiary
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Adaptor Proteins, Signal Transducing
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Dihydrotestosterone
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Proto-Oncogene Proteins c-myc
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Inhibitory Concentration 50
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Histone Demethylases
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number of publications: 28
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Physical Conditioning, Animal
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uniqueness weight: 0.950082
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Genes, Reporter
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Gene Expression Regulation, Enzymologic
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Retinoblastoma Binding Proteins
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Bridged Bicyclo Compounds, Heterocyclic
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Transcription Factor AP-1
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uniqueness weight: 0.97723
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DNA Damage
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Positive Transcriptional Elongation Factor B
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Receptor Protein-Tyrosine Kinases
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Epigenesis, Genetic
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Guanylate Cyclase
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Reverse Transcriptase Polymerase Chain Reaction
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RNA Polymerase II
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Adenine
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Response Elements
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Inhibitor of Apoptosis Proteins
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DNA, Neoplasm
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Carcinoma
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G1 Phase
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Luciferases
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Structural Homology, Protein
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Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
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Spiro Compounds
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Protein Kinase C-alpha
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Binding Sites
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Transcription Factors
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Testosterone
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Dehydroepiandrosterone
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Gene Knockout Techniques
MeSH DescriptorUI: D055786
MeSH semantic group name: Procedures
number of authors: 82
number of publications: 101
uniqueness weight: 0.96192
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Base Sequence
MeSH DescriptorUI: D001483
MeSH semantic group name: Chemicals & Drugs
MeSH semantic group name: Genes & Molecular Sequences
number of authors: 348
number of publications: 1346
uniqueness weight: 0.813092
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Amino Acid Motifs
MeSH DescriptorUI: D020816
MeSH semantic group name: Concepts & Ideas
number of authors: 99
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uniqueness weight: 0.950077
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Tissue Array Analysis
MeSH DescriptorUI: D046888
MeSH semantic group name: Procedures
number of authors: 29
number of publications: 39
uniqueness weight: 0.984738
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Zebrafish
MeSH DescriptorUI: D015027
MeSH semantic group name: Living Beings
number of authors: 87
number of publications: 373
uniqueness weight: 0.76613
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Histone-Lysine N-Methyltransferase
MeSH DescriptorUI: D011495
MeSH semantic group name: Chemicals & Drugs
number of authors: 30
number of publications: 39
uniqueness weight: 0.977558
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Transcriptional Activation
MeSH DescriptorUI: D015533
MeSH semantic group name: Physiology
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uniqueness weight: 0.920527
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Orchiectomy
MeSH DescriptorUI: D009919
MeSH semantic group name: Procedures
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uniqueness weight: 0.990459
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SOX9 Transcription Factor
MeSH DescriptorUI: D055758
MeSH semantic group name: Chemicals & Drugs
number of authors: 9
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uniqueness weight: 0.993303
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Nerve Tissue Proteins
MeSH DescriptorUI: D009419
MeSH semantic group name: Chemicals & Drugs
number of authors: 179
number of publications: 432
uniqueness weight: 0.813293
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Castration
MeSH DescriptorUI: D002369
MeSH semantic group name: Procedures
number of authors: 11
number of publications: 43
uniqueness weight: 0.996854
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Cell Line, Tumor
MeSH DescriptorUI: D045744
MeSH semantic group name: Anatomy
number of authors: 389
number of publications: 1611
uniqueness weight: 0.711241
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Receptors, Cytoplasmic and Nuclear
MeSH DescriptorUI: D018160
MeSH semantic group name: Chemicals & Drugs
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number of publications: 151
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Immunoblotting
MeSH DescriptorUI: D015151
MeSH semantic group name: Procedures
number of authors: 116
number of publications: 207
uniqueness weight: 0.96211
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Phosphorylation
MeSH DescriptorUI: D010766
MeSH semantic group name: Phenomena
number of authors: 308
number of publications: 977
uniqueness weight: 0.809191
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Matrix Metalloproteinases
MeSH DescriptorUI: D020782
MeSH semantic group name: Chemicals & Drugs
number of authors: 15
number of publications: 17
uniqueness weight: 0.989213
type: Concept

Medicine
type: Department
type: Organization

UMass Chan Medical School
type: Organization

ADJUNCT ASSOCIATE PROFESSOR
sort order: 44
type: Faculty Rank

Cell Plasticity
MeSH DescriptorUI: D000066670
number of authors: 17
number of publications: 24
uniqueness weight: 0.974574
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Poly(ADP-ribose) Polymerase Inhibitors
MeSH DescriptorUI: D000067856
number of authors: 19
number of publications: 26
uniqueness weight: 0.969419
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Dutasteride
MeSH DescriptorUI: D000068538
number of authors: 3
number of publications: 4
uniqueness weight: 0.998544
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Enhancer of Zeste Homolog 2 Protein
MeSH DescriptorUI: D000071221
number of authors: 15
number of publications: 17
uniqueness weight: 0.990571
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Transcriptional Regulator ERG
MeSH DescriptorUI: D000071230
number of authors: 7
number of publications: 9
uniqueness weight: 0.996191
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Soluble Guanylyl Cyclase
MeSH DescriptorUI: D000071756
number of authors: 3
number of publications: 4
uniqueness weight: 0.998552
type: Concept

NIMA-Interacting Peptidylprolyl Isomerase
MeSH DescriptorUI: D000072340
number of authors: 5
number of publications: 5
uniqueness weight: 0.998171
type: Concept

Promyelocytic Leukemia Zinc Finger Protein
MeSH DescriptorUI: D000075722
number of authors: 3
number of publications: 3
uniqueness weight: 0.999586
type: Concept

Demethylation
MeSH DescriptorUI: D000073398
number of authors: 4
number of publications: 4
uniqueness weight: 0.99827
type: Concept

Transcription Factor 4
MeSH DescriptorUI: D000073940
number of authors: 3
number of publications: 3
uniqueness weight: 0.999061
type: Concept

Rapamycin-Insensitive Companion of mTOR Protein
MeSH DescriptorUI: D000076226
number of authors: 4
number of publications: 12
uniqueness weight: 0.992321
type: Concept

HEK293 Cells
MeSH DescriptorUI: D057809
MeSH semantic group name: Anatomy
number of authors: 244
number of publications: 629
uniqueness weight: 0.834218
type: Concept

Androgen Receptor Antagonists
MeSH DescriptorUI: D059002
MeSH semantic group name: Chemicals & Drugs
number of authors: 4
number of publications: 8
uniqueness weight: 0.99628
type: Concept

Single-Cell Analysis
MeSH DescriptorUI: D059010
MeSH semantic group name: Procedures
number of authors: 79
number of publications: 127
uniqueness weight: 0.892502
type: Concept

Cell Cycle Checkpoints
MeSH DescriptorUI: D059447
MeSH semantic group name: Physiology
number of authors: 31
number of publications: 48
uniqueness weight: 0.970106
type: Concept

Transcriptome
MeSH DescriptorUI: D059467
MeSH semantic group name: Concepts & Ideas
MeSH semantic group name: Genes & Molecular Sequences
number of authors: 208
number of publications: 409
uniqueness weight: 0.756774
type: Concept

TOR Serine-Threonine Kinases
MeSH DescriptorUI: D058570
MeSH semantic group name: Chemicals & Drugs
number of authors: 65
number of publications: 129
uniqueness weight: 0.929401
type: Concept

Epithelial-Mesenchymal Transition
MeSH DescriptorUI: D058750
MeSH semantic group name: Physiology
number of authors: 48
number of publications: 83
uniqueness weight: 0.94951
type: Concept

5-alpha Reductase Inhibitors
MeSH DescriptorUI: D058891
MeSH semantic group name: Chemicals & Drugs
number of authors: 8
number of publications: 11
uniqueness weight: 0.98787
type: Concept

Cellular Reprogramming
MeSH DescriptorUI: D065150
MeSH semantic group name: Physiology
number of authors: 38
number of publications: 42
uniqueness weight: 0.974418
type: Concept

Cytochrome P-450 Enzyme Inhibitors
MeSH DescriptorUI: D065607
MeSH semantic group name: Chemicals & Drugs
number of authors: 6
number of publications: 6
uniqueness weight: 0.996388
type: Concept

Proteolysis
MeSH DescriptorUI: D059748
MeSH semantic group name: Physiology
number of authors: 85
number of publications: 159
uniqueness weight: 0.899543
type: Concept

Wnt Signaling Pathway
MeSH DescriptorUI: D060449
MeSH semantic group name: Physiology
number of authors: 67
number of publications: 85
uniqueness weight: 0.927954
type: Concept

Polycomb Repressive Complex 2
MeSH DescriptorUI: D063151
MeSH semantic group name: Chemicals & Drugs
number of authors: 13
number of publications: 17
uniqueness weight: 0.992706
type: Concept

Mitochondrial Dynamics
MeSH DescriptorUI: D063154
MeSH semantic group name: Physiology
number of authors: 9
number of publications: 10
uniqueness weight: 0.992953
type: Concept

CRISPR-Cas Systems
MeSH DescriptorUI: D064113
MeSH semantic group name: Physiology
number of authors: 121
number of publications: 370
uniqueness weight: 0.741149
type: Concept

Prostatic Neoplasms, Castration-Resistant
MeSH DescriptorUI: D064129
MeSH semantic group name: Disorders
number of authors: 17
number of publications: 46
uniqueness weight: 0.9371
type: Concept

Heterografts
MeSH DescriptorUI: D064593
MeSH semantic group name: Anatomy
number of authors: 40
number of publications: 68
uniqueness weight: 0.975691
type: Concept

ErbB Receptors
MeSH DescriptorUI: D066246
MeSH semantic group name: Chemicals & Drugs
number of authors: 79
number of publications: 127
uniqueness weight: 0.928632
type: Concept