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Orthopedics and Physical Rehabilitation
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Medicine
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Neurobiology
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Pathology
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Program in Molecular Medicine
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Radiation Oncology
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Radiology
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RNA Therapeutics Institute
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Systems Biology
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Urology
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College of Engineering
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College of Natural Sciences
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Chemistry
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Dept of Veterinary And Animal Science
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Electrical And Computer Engineering
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Food Science
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Veterinary & Animal Sciences; Pioneer Valley Life
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Gastroenterology
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Health Informatics And Implementation Science
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Hematology/Oncology
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UMass Chan Medical School
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University of Massachusetts Amherst
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Rando, Oliver
first name: Oliver
last name: Rando
full name: Oliver J Rando MD, PhD
has faculty rank: Professor
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Person ID: 1067
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Endowed Chair Honorary Title: Endowed Chair in Biochemistry and Molecular Biotechnology II
Post Docs: For more information about the Postdoctoral position in Dr. Rando’s lab please use the link provided. Post doc position
Rotation Projects: Rotation projects are available to study chromatin structure and function. Project 1. Measure histone dynamics in yeast. Histone dynamics play major roles in chromatin metabolism and in the inheritance of chromatin states. To measure histone replacement rates in yeast, we have created yeast strains carrying inducible epitope-tagged histones H3 and H2A. Using microarrays, we will measure histone replacement rates in a variety of mutant yeast to ascertain the role of various chromatin remodeling factors in histone exchange reactions. Project 2. Characterize mechanisms for epigenetic inheritance in yeast. We have identified a variety of genes whose expression state in yeast is epigenetically heritable. We will screen the yeast genome for genes that affect the inheritance of these expression patterns. Project 3. Measure histone dynamics in embryonic stem cells. Embryonic stem cells are pluripotent cells that can give rise to every type of cell in the adult animal. The role of chromatin structure in maintaining this pluripotent state is poorly understood, but it appears that stem cell chromatin is exceptionally labile relative to that in differentiated cells. We will create stem cell lines with inducible tagged histones to measure histone replacement rates across the mouse genome.
preferred title: Professor

Zhu, Lihua
first name: Lihua
last name: Zhu
full name: Lihua Zhu PhD
has faculty rank: Professor
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preferred title: Professor

Kelliher, Michelle
first name: Michelle
last name: Kelliher
full name: Michelle A Kelliher PhD
has faculty rank: Professor
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Person ID: 115
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Endowed Chair Honorary Title: Our Danny Cancer Fund Chair in Biomedical Research I
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Kelliher for additional details.
Rotation Projects: Please visit the Kelliher Lab website at: http://labs.umassmed.edu/kelliherlab/ to learn more about our current research areas. 1. Identify genes/pathways that mediate leukemia-initiating cell survival 2. Understand the molecular basis of glucocorticoid resistance in leukemia 3. Examine contribution of RIPK1 kinase in inflammatory and autoimmune disease mouse models. 4. Reveal tissue-specific roles for RIPK1 in cell death and inflammation. Use conditional Ripk1 allele to investigate effects of Ripk1 deletion in liver, pancreas and antigen presenting cells.
preferred title: Professor

Weng, Zhiping
first name: Zhiping
last name: Weng
full name: Zhiping Weng PhD
has faculty rank: Chair And Professor
latitude: 42.27985300000000
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Person ID: 1152
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Endowed Chair Honorary Title: Li Weibo Chair in Biomedical Research
Post Docs: The project aims to develop computational algorithms and software programs for analyzing high-throughput sequence data such as ChIP-Seq RNA-Seq small RNA sequencing data. PhD required. A strong background in computational biology especially experience with analyzing high-throughput sequencing data is highly desirable. Excellent communication and writing skills and the ability to work with experimental and computational collaborators are essential. To apply please forward CV cover letter and three references to: Zhiping.Weng@umassmed.edu
Rotation Projects: Please contact Dr. Weng for information on rotations that are available in her lab.
preferred title: Chair and Professor

Gao, Guangping
first name: Guangping
last name: Gao
full name: Guangping Gao PhD
has faculty rank: Chair And Professor
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Person ID: 1177
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Endowed Chair Honorary Title: Penelope Booth Rockwell Chair in Biomedical Research
Lab URL: https://www.umassmed.edu/gaolab/
Summary: Focus: Adeno-associated virus vector mediated gene transfer for gene therapy, gene therapy of inherited neurodegenerative Canavan Disease
preferred title: Chair and Professor

Mao, Junhao
first name: Junhao
last name: Mao
full name: Junhao Mao PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 1191
person in primary position: Professor
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Post Docs: Postdoctoral positions are available for this lab. Please contact Junhao Mao directly, 508-856-4149 or via email, Junhao.Mao@umassmed.edu
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866544

Fazzio, Thomas
first name: Thomas
last name: Fazzio
full name: Thomas G Fazzio PhD
has faculty rank: Professor
latitude: 42.27587600000000
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Person ID: 1385
person in primary position: Professor
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Post Docs: A postdoctoral position is available to study in this laboratory. Please contact Dr. Fazzio for details.
Rotation Projects: Rotation Projects <p >Rotation projects are available on any of the main topics being studied in the lab. Our recent RNAi screen identifying chromatin regulators necessary for ES cell self-renewal has opened up several new potential projects aimed at identification of the important functions of these regulators in ES cells. Alternatively, projects focusing on the mechanisms of action and regulation of Tip60-p400 complex, or examining the functions of chromatin regulators in cancer stem cells are also possible, depending on the student’s interests. Rotation projects will usually involve some combination of mammalian cell culture, cell and molecular biology, biochemistry, and genomic approaches.
preferred title: Professor

Latz, Eicke
first name: Eicke
last name: Latz
full name: Eicke Latz MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27985300000000
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Person ID: 153
person in primary position: Adjunct Professor
type: Agent
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preferred title: Adjunct Professor

Fitzgerald, Katherine
first name: Katherine
last name: Fitzgerald
full name: Katherine A Fitzgerald PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 202
person in primary position: Professor
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Endowed Chair Honorary Title: Worcester Foundation for Biomedical Research Chair III
Rotation Projects: Please email Kate.Fitzgerald@umassmed.edu if you are interested in rotations.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866427
webpage: https://profiles.umassmed.edu/profile/28866493

Shultz, Leonard
first name: Leonard
last name: Shultz
full name: Leonard Donald Shultz PhD
has faculty rank: Professor
latitude: 44.36637960000000
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Person ID: 2863
person in primary position: Professor
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preferred title: Professor

Czech, Michael
first name: Michael
last name: Czech
full name: Michael Paul Czech PhD
has faculty rank: Professor Emeritus
latitude: 42.27913450000000
longitude: -71.76550630000000
Person ID: 289
person in primary position: Professor Emeritus
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type: Person
Endowed Chair Honorary Title: Isadore and Fannie Foxman Chair in Medical Research
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Czech for additional details.
Rotation Projects: Mentoring……………………………………………………………………………………………………… The Czech laboratory is active in mentoring graduate students and postdoctoral fellows. Many former student and postdoctoral trainees of the Czech laboratory are now internationally recognized professors at major universities and medical schools. These former lab members include: Paul Pilch, Professor of Biochemistry, Boston University School of Medicine Jeffrey Pessin, Professor and Director of the Diabetes Center, Einstein College of Medicine Joan Massague, Director, Sloan Kettering Institute Roger Davis, HHMI investigator and Professor of Molecular Medicine, UMASS Medical School Silvia Corvera, Professor of Molecular Medicine, Co-Director of the MD/PhD Program, UMASS Medical School Carla Greenbaum, Vice Chair and Director of Clinical Research, Benaroya Research Institute Jes Klarlund, Professor of Ophthalmology, University of Pittsburgh Medical Center Rob Lewis, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Richard MacDonald, Professor of Biochemistry and Molecular Biology, Eppley Cancer Institute, University of Nebraska Medical Center Assia Shisheva, Professor of Physiology, Wayne State School of Medicine. Mark Sleeman, Professor of Physiology, Monash University, Australia John Harris, Associate Professor of Medicine, UMASS Medical School Zhen Jiang, Associate Professor of Pharmacology and Medicine, Boston University Vishu Puri, Professor of Biomedical Sciences, Ohio University Olga Gupta, Assistant Professor of Pediatrics and Medicine, University of Texas Southwestern Medical Center Tim Fitzgibbons, Assistant Professor of Medicine, UMASS Medical School Myriam Aouadi, Assistant Professor, Integrated Cardio Metabolic Centre, Karolinska Institute Adilson Guilherme, Associate Professor, University of Massachusetts Medical School Our laboratory currently offers graduate student Rotation Projects (examples below and others available) and Thesis Research …
preferred title: Professor Emeritus

Davis, Roger
first name: Roger
last name: Davis
full name: Roger J Davis PhD, FRS
has faculty rank: Chair And Professor
latitude: 42.27913100000000
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Person ID: 3130
person in primary position: Chair and Professor
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Endowed Chair Honorary Title: H. Arthur Smith Chair in Cancer Research
Rotation Projects: Rotation Projects Laboratory rotations are available to study signal mammalian transduction mechanisms. Several projects are available, including studies of protein kinase cascades, gene expression, the cell cycle, and apoptosis. Targeted gene disruption approaches in mice combined with biochemical and molecular biology studies will be examined.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866429

Zierath, Juleen
first name: Juleen
last name: Zierath
full name: Juleen R Zierath PhD
has faculty rank: ADJUNCT PROFESSOR
latitude: 42.27587600000000
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Person ID: 3151
person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Xiang, Yang
first name: Yang
last name: Xiang
full name: Yang Xiang PhD
has faculty rank: Associate Professor
latitude: 42.27737440000000
longitude: -71.76346650000000
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Person ID: 3180
person in primary position: Associate Professor
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Rotation Projects: One rotation student is expected in the lab to characterize the expression and function of Drosophila gustatory receptor 28b (Gr28b) in phototransduction and taste sensation. Please contact Dr. Yang Xiang for details.<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p> <o:p> </o:p> Yang Xiang, Ph.D. University of Massachusetts Medical School Department of Neurobiology, LRB 725 364 Plantation Street Worcester, MA 01605 USA phone: 508-856-6816 (office) e-mail: yang.xiang@umassmed.edu<o:p></o:p>
preferred title: Associate Professor

Khvorova, Anastasia
first name: Anastasia
last name: Khvorova
full name: Anastasia Khvorova PhD
has faculty rank: Professor
latitude: 42.27767280000000
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Person ID: 3413
person in primary position: Professor
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Endowed Chair Honorary Title: Remondi Family Chair in Biomedical Research
Post Docs: POSTDOCTORAL POSITION: RNAI PRECLINICAL DEVELOPMENT Excellent training opportunity for a person considering industrial carrier in drug development Oligonucleotides represent a new class of drugs, which have the promise to become a major class of future therapeutics. There are several classes of oligonucleotides which can efficiently silence genes in various tissues with acceptable level of toxicity. There are also new chemistries being developed to further improve oligonucleotide tissue distribution and cellular uptake. The successful candidate will be a key part of an intra-disciplinary team working with biologists and chemists to develop novel types of therapeutics for treatment of neurological disease, liver disease and orphan indications. The work will include compounds identification, screening, characterization, in vivo efficacy and PK/PD studies, novel assays development etc. In addition exposure and training in nucleic acid pre-clinical development, project management etc will be provided. QUALIFICATIONS: Applicants must have (or expect to obtain shortly) a Ph.D. in Chemistry, Organic Chemistry Biochemistry, Cell Biology, Molecular Biology or a related field , be bright, ambitious, independent and collaborative and ideally, have research experience in nucleic acid molecular cell biology or pharmacology.
Post Docs: RNAI MEDICINAL CHEMISTRY/ RNA OLIGONUCLEOTIDE CHEMISTRY Develop and characterize novel RNA chemistries to promote efficient oligonucleotide internalization and tissue distribution. Oligonucleotides represent a new class of drugs, which have the promise to become a major class of future therapeutics. There are several chemistries and formulations developed by us and others that effectively support oligo internalization and favorable PK/PD. In most cases in vivo efficacy is limited by (1) poor PK (2) inefficient tissue distribution (3) compound entrapment in biologically inactive intracellular compartments. The objective of future studies will be development of novel chemistries, which promote receptor mediated cellular internalization and/ or endosomal escape. The successful candidate will be responsible for the design and synthesis of novel RNA precursors, optimization of RNA synthesis and conjugation protocols and interface with the biology part of the lab. In addition, exposure to pre-clinical development programs and oligonucleotide manufacturing will be available. QUALIFICATIONS: Applicants must have (or expect to obtain shortly) a Ph.D. in Chemistry, Organic Chemistry Biochemistry, Cell Biology, Molecular Biology or a related field , be bright, ambitious, independent and collaborative and have previous experience in nucleic acid / oligonucleotide chemistry.
Post Docs: SMALL RNA TRAFFICKING Discover, characterize and adapt mechanisms of small RNA extracellular and intracellular trafficking for development of novel classes of oligonucleotide drugs. A serious limitation in realizing the potential of oligonucleotide based therapies has been the exceedingly inefficient transit of oligonucleotides from outside cells to the intracellular compartments where the biologically relevant activity happens. On the other hand, there are multiple lines of evidence supporting the notion that nature has implemented evolutionarily conserved mechanisms and pathways for efficiently trafficking small RNAs across cellular boundaries. The objective of future studies will be the systematic evaluation of mechanisms of cellular uptake of different classes of oligonucleotides and their comparison to mechanisms of native RNA trafficking using a combination of experimental approaches, including advanced RNA chemistry and high temporal and spatial resolution microscopy in living cells, Mass spectrometry, cell biology and others. The successful candidate will work closely with Victor Ambros and Silvia Corvera labs and the UMASS imaging group and receive training in RNA chemistry, biochemistry, cell biology and pre-clinical development. QUALIFICATIONS:Applicants must have (or expect to obtain shortly) a Ph.D. in Chemistry, Organic Chemistry Biochemistry, Cell Biology, Molecular Biology or a related field , be bright, ambitious, independent and collaborative and ideally, have research experience in nucleic acid molecular and cell biology
Rotation Projects: Our laboratory uses a combination of nucleic acid and oligonucleotide chemistry, biochemistry, cell biology, and pharmacology and develops and evaluate novel technologies for development of oligonucleotide therapeutics. A rotation project is available to develop and identify chemically modified self-delivering RNAi compounds for treatment of Huntington and other diseases.
preferred title: Professor

Heneka, Michael
first name: Michael
last name: Heneka
full name: Michael Thomas Heneka MD
has faculty rank: ADJUNCT PROFESSOR
latitude: 50.70274210000000
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Person ID: 3432
person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Golenbock, Douglas
first name: Douglas
last name: Golenbock
full name: Douglas T Golenbock MD
has faculty rank: Professor
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Person ID: 345
person in primary position: Professor
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Endowed Chair Honorary Title: Neil and Margery Blacklow Chair in Infectious Diseases and Immunology
preferred title: Professor

Epstein, Mara
first name: Mara
last name: Epstein
full name: Mara Meyer Epstein ScD, ScM
has faculty rank: Associate Professor
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Person ID: 3469
person in primary position: Associate Professor
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preferred title: Associate Professor

Szabo, Gyongyi
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo MD, PhD
has faculty rank: ADJUNCT PROFESSOR
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Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
preferred title: Adjunct Professor

Lee, Michael
first name: Michael
last name: Lee
Twitter: https://profiles.umassmed.edu/profile/28867137
full name: Michael J Lee PhD
has faculty rank: Professor
latitude: 42.26259320000000
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Person ID: 3679
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Lab URL: https://umassmed.edu/Lee-Lab
Post Docs: A postdoctoral position is available within the Lee Lab. Please see our webpage for more information. Application materials can be sent directly to Dr. Lee, and please have 3 letters of reference sent by email directly to Dr. Lee, including the applicants name in the subject line.
Rotation Projects: <?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p>We are always very excited to have students rotate in the Lee Lab! Projects are available for those interested in developing an experimental and/or computational skill set, and those interested in training across these disciplines are always encouraged to do so. By rotating in the Lee Lab, you will gain expertise in a variety of quantitative high-throughput techniques in the area of proteomics, signal transduction, network biology, and genomics. We aim to actively promote an interactive and fun atmosphere. Students will participate in various lab and PSB functions, including weekly lab meetings, weekly Systems Biology journal club, and at the end of the rotation, students will present their work to the lab/department.</o:p>
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866583

Jerry, D Joseph
first name: D Joseph
last name: Jerry
full name: D Joseph Jerry BS, MS, PhD
has faculty rank: Professor
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Lian, Jane
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Rotello, Vincent
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Xiao, Hang
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Shao, Rong
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Xia, Qiangfei
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Zamore, Phillip
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Endowed Chair Honorary Title: Gretchen Stone Cook Chair in Biomedical Sciences
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Zamore for additional details
Rotation Projects: Potential Rotation Projects Our laboratory uses a combination of biochemistry, cell biology, and genetics to dissect the RNAi pathway. A rotation project is available to explore the mechanisms that underlie the RNAi phenomenon or the biological pathways in which RNAi enzymes participate in flies, mice and humans.
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webpage: https://profiles.umassmed.edu/profile/28866555
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Castilla, Lucio
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Post Docs: The Castilla laboratory is accepting applications for postdoctoral positions. The candidates should be close to or have recently graduated with a Ph.D. or M.D./Ph.D. degree (within 1 year) in the fields of Cancer Biology, Genetics, Biochemistry, Cell Biology or related field. The candidates must also have a proven track record of productivity and research experience. Previous experience using immunocompromised and transgenic mice, in vitro and in vivo assays with small molecules or nanoparticles, or hematopoietic stem cells is preferred. We are looking for highly motivated candidates with excellent communication skills, and able to work independently and in cooperation with other members of the laboratory. Applicants should send their CV, a cover letter summarizing background and research interests, and three letters of references by electronic mail to: Dr. Lucio H. Castilla, Associate Professor University of Massachusetts Medical School Lucio.Castilla@umassmed.edu
Rotation Projects: Potential Rotation Projects<?xml:namespace prefix = u5 /><u5:p></u5:p><?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p> <u5:p> </u5:p><o:p></o:p> 1. Role of core binding factors on hematopoietic stem cell function and survival. We use molecular pharmacologic and functional approaches to study the role of the RUNX factors in self renewal and proliferation of hematopoietic stem and progenitor cells, using genetically modified mice and human progenitor cells. <u5:p></u5:p><o:p></o:p> <u5:p> </u5:p><o:p></o:p> 2. Study the molecular mechanism of leukemia initiation and maintenance. Transcription factors and components of cytokine signaling are frequently mutated in human cancer, including leukemia. These mutations deregulate the proliferation, differentiation and survival of hematopoietic stem cells. We study the role of members of RUNX and RAS protein families in the function of hematopoietic stem cell function, pre-leukemic progenitors, and leukemia-initiating cells. <u5:p></u5:p><o:p></o:p> <u5:p> </u5:p><o:p></o:p> 3. Translational research: Recent evidence suggests that inhibition of pathways activated by gene mutations can be used to eliminate leukemia cells, and not affecting normal cells. We use small molecule inhibitors of leukemia oncogenes to test whether repression of activated pathways hinder survival of leukemia initiating cells, and eliminate leukemia. We use a combination of mouse models and human leukemia cells to test the efficacy, specificity and toxicity of candidate inhibitors, as single agents or in combination with first line leukemia drugs.<u5:p></u5:p><o:p></o:p>
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Imbalzano, Anthony
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Post Docs: Please contact Dr. Imbalzano to discuss the possibility of a postdoctoral training.See lab research interests and publications for recent topics of research. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
Rotation Projects: Please contact Dr. Imbalzano to discuss the possibility of a rotation project. Rotation projects are generally based on current work and tailored to the interests of the student. See lab research interests and publications for recent topics. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
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Richter, Joel
first name: Joel
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full name: Joel Richter PhD
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Endowed Chair Honorary Title: Arthur F. Koskinas Chair in Neuroscience
Rotation Projects: Many rotation projects are available so please inquire.
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Schiffer, Celia
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full name: Celia A Schiffer PhD
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Endowed Chair Honorary Title: Arthur F. and Helen P. Koskinas Professor in Biochemistry and Molecular Biotechnology
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Ip, Yicktung
first name: Yicktung
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Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Ip for additional details.
Rotation Projects: Rotation Projects Project #1: Mechanistic study of isolated mutants that show abnormal intestinal stem cell division phenotypes. Project #2:Perform transgenic RNAi-based genetic screen for genes required for intestinal stem cell response to tissue damage.
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Greiner, Dale
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Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
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Peterson, Craig
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Endowed Chair Honorary Title: Elisabeth Chair I
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Walz, J.
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Endowed Chair Honorary Title: UMass Memorial Kaur Chair in Anesthesia and Perioperative Medicine
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Goel, Hira
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Dekker, Job
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Person ID: 759
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Endowed Chair Honorary Title: Joseph J. Byrne Chair in Biomedical Research
Rotation Projects: ? Rotation Projects Multiple rotation projects are available in several areas related to long-range gene regulation and higher order chromosome organization. Projects include thorough analyses of the biochemical mechanisms of long-range gene regulation of specific disease-related genes, as well as large-scale analyses of chromosome organization using high-throughput genomics technologies (5C and Hi-C). The lab employs a wide range of experimental approaches, including cell culture, protein biochemistry, microscopy, genomics as well computational approaches such as bioinformatics and modeling. Specific rotation projects are determined dependent on the interest of the student.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866525
webpage: https://profiles.umassmed.edu/profile/28866572

Cantor, Sharon
first name: Sharon
last name: Cantor
full name: Sharon B Cantor PhD
has faculty rank: Professor
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Person ID: 828
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Endowed Chair Honorary Title: Gladys Smith Martin Chair in Oncology
Post Docs: A post-doctoral position is available immediately to study the role of genes found in a genome-wide RNAi screen to regulate the cellular response to the chemotherapy agent, cisplatin. The goal is to determine whether these genes function as tumor suppressor and/or regulate the mechanism of DNA repair processing. The laboratory is interested in understanding the role of hereditary cancer genes of the BRCA-Fanconi anemia pathway in DNA damage repair and tumor suppression. We seek motivated candidates with a PhD and background in cancer cell biology. Experience in mouse cancer models is desirable. The exceptional training environment within the Department of Cancer Biology at UMASS Medical School offers a rigorous and interactive research environment covering several aspects of tumor biology. Applicants should have excellent communication skills, and ability to conduct research independently and as a team. To apply, please send your CV with bibliography, a brief description of research experience and contact information for at least two references via email.
Rotation Projects: The laboratory is interested in a range of DNA replication/repair-related topics including (i) Defining biomarkers of “BRCAness” that signifies deficiency in the hereditary breast/ovarian cancer genes, BRCA1 or BRCA2, (ii) Targeting BRCAness as a replication gap vulnerability, (iii) Defining why replication proficiency requires the FANCJ helicase disengage mismatch repair proteins, (iv) Determining if suppressing gaps improves the health of Fanconi anemia patient cells, (v) Hunting down the cancer vulnerability that defines curability, (vi) performing functional genomic screens to uncover mechanisms regulating chemotherapy resistance.
preferred title: Professor

FitzGerald, Thomas
first name: Thomas
last name: FitzGerald
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Endowed Chair Honorary Title: UMass Memorial Chair in Radiation Oncology
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Shaw, Leslie
first name: Leslie
last name: Shaw
full name: Leslie M Shaw PhD
has faculty rank: Professor
latitude: 42.27985300000000
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Person ID: 900
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Mercurio, Arthur
first name: Arthur
last name: Mercurio
full name: Arthur M Mercurio PhD
has faculty rank: Professor
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Person ID: 901
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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
preferred title: Professor

Anesthesiology and Perioperative Medicine
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UMass Chan – Baystate Regional Campus
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ADJUNCT ASSOCIATE PROFESSOR
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ADJUNCT PROFESSOR
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Usmani, Saad
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Population and Quantitative Health Sciences
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Lai, Jiann-Jyh
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Bloch, Boris
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Ruscetti, Marcus
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Biochemistry and Molecular Biotechnology
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Medicine at UMass Chan - Baystate
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Pitarresi, Jason
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Weiss, Glen
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https://profiles.umassmed.edu/profile/32784143
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Genomics and Computational Biology
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Surgery at UMass Chan - Lahey
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Basic Pathology
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Breast Imaging
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Endocrinology & Diabetes
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Health System Science
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Infectious Diseases
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Innate Immunity
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Orthopedics Research
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Pulmonary Medicine
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Adjunct Professor
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Professor
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Professor
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Vascular Anesthesia
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HR job title: Chair and Professor
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Professor
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Chair and Professor
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position in department: Genomics and Computational Biology
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HR job title: Chair and Professor
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Adjunct Professor
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position in division: Breast Imaging
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HR job title: Adjunct Professor
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Martinez, Fernando
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Professor
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position in division: Pulmonary Medicine
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HR job title: Professor
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Professor
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position in department: Systems Biology
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HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Infectious Diseases
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type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Hartford, Alan
first name: Alan
last name: Hartford
full name: Alan Charles Hartford MD, PhD, FACR, FASTRO
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Person ID: 10248071
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preferred title: Professor

Professor
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position in department: Radiation Oncology
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HR job title: Professor
position in organization: UMass Chan Medical School

Professor Emeritus
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position in department: Program in Molecular Medicine
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HR job title: Professor Emeritus
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Professor
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position in department: Biochemistry and Molecular Biotechnology
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HR job title: Professor
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Chair and Professor
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position in department: Anesthesiology and Perioperative Medicine
position in division: Vascular Anesthesia
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HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Instructor
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type: Faculty Rank

Professor
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type: Faculty Rank

Professor Emeritus
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type: Faculty Rank

Research Assistant Professor
sort order: 16
type: Faculty Rank

Assistant Professor
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type: Faculty Rank

Associate Professor
sort order: 10
type: Faculty Rank

Chair And Professor
sort order: 4
type: Faculty Rank

Gregory, Richard
first name: Richard
last name: Gregory
full name: Richard Gregory PhD
has faculty rank: Chair And Professor
latitude: 42.27525450000000
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Person ID: 10248239
person in primary position: Chair and Professor
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Endowed Chair Honorary Title: Eleanor Eustis Farrington Chair in Cancer Research
preferred title: Chair and Professor

Clements, Matthew
first name: Matthew
last name: Clements
full name: Matthew B Clements MD, MS
has faculty rank: Assistant Professor
latitude: 42.48526100000000
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Person ID: 10248274
person in primary position: Assistant Professor
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type: Person
preferred title: Assistant Professor

Professor
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position in department: Medicine
position in division: Endocrinology & Diabetes
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HR job title: Professor
position in organization: UMass Chan Medical School

Assistant Professor
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position in department: Surgery at UMass Chan - Lahey
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HR job title: Assistant Professor
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Associate Professor
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position in department: Medicine
position in division: Health System Science
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Genetic and Cellular Medicine
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type: Organization

Assistant Professor
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position in department: Medicine
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Molecular, Cell and Cancer Biology
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Chair and Professor
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position in department: Molecular, Cell and Cancer Biology
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sort order: 1
type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Chair and Professor
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position in department: RNA Therapeutics Institute
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sort order: 1
type: Position
HR job title: Chair and Professor
position in organization: UMass Chan Medical School

Professor
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position in department: RNA Therapeutics Institute
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: RNA Therapeutics Institute
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Surgery at UMass Chan - Lahey
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sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Shin, Dong-Soo
first name: Dong-Soo
last name: Shin
full name: Dong-Soo Shin PhD, RN
has faculty rank: ADJUNCT PROFESSOR
Person ID: 10248397
person in primary position: Adjunct Professor
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preferred title: Adjunct Professor

Vanni, Alex
first name: Alex
last name: Vanni
full name: Alex Vanni MD, FACS
has faculty rank: Professor
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Person ID: 10248404
person in primary position: Professor
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Summary: Dr. Alex J. Vanni is an internationally recognized expert in reconstructive urologic surgery and a Professor of Urology at Lahey Hospital and Medical Center, where he serves as Director of the Center for Reconstructive Urologic Surgery. He specializes in the treatment of urethral stricture disease and advanced male genitourinary reconstruction.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/111866126

Associate Professor
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position in department: Surgery at UMass Chan - Lahey
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sort order: 1
type: Position
HR job title: Associate Professor
position in organization: UMass Chan Medical School

Canes, David
first name: David
last name: Canes
full name: David Canes MD
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Person ID: 10248485
person in primary position: Associate Professor
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preferred title: Associate Professor

Chair and Professor
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position in department: Genetic and Cellular Medicine
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sort order: 1
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HR job title: Chair and Professor
position in organization: UMass Chan Medical School