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Health Informatics And Implementation Science
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Preventive And Behavioral Medicine
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Renal Medicine
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Biostatistics And Health Services Research
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Rheumatology
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Biostatistics And Epidemiology
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UMass Chan Medical School
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University of Massachusetts Amherst
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Pagoto, Sherry
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Tjia, Jennifer
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Gore, Joel
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Allison, Jeroan
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Hayman, Laura
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Bertone-Johnson, Elizabeth
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Boyer, Katherine
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Rosal, Milagros
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Wolfe, Scot
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Post Docs: Postdoctoral Fellow Applications are being accepted for one position. A position is available to develop Cys2His2 zinc finger proteins (ZFPs) for the treatment of monogenic disorders. This project will focus on the creation of ZFPs with novel DNA-binding specificity to recognize sequence elements within genomic loci of therapeutic interest. In collaboration with other laboratories, we will evaluate the activity of these ZFP-based gene therapy reagents in vitro and in vivo in relevant disease models. Applicants will also have the opportunity to learn to apply Cas9 and Cas12a editing systems in vivo.
Rotation Projects: Potential Rotation Projects Improving the Precision of CRISPR/Cas9 nucleases for gene therapy applications: We are working to improve the precision of the CRISPR/Cas9 system to generate nucleases that will cleave at only a single site in the genome. These engineering efforts focus on increasing the DNA-editing precision of Cas9 and using protein engineering to introduce new properties into the nuclease. Much of this work is now transitioning to the use of Cas9 (and Cas12a) protein-RNA complexes. These modified nucleases will then be applied to patient derived cell-culture systems for the targeted repair or inactivation of disease-causing alleles. With the eventual goal of creating therapeutics for Sickle Cell Disease, beta-Thalassemia, HIV, Limb Girdle Muscular Dystrophy, Hermansky Pudlak Syndrome and other monogenic disorders. ex vivo genome editing in CD34+ HSPCs: We are developing improved Cas9 proteins for delivery ex vivo into CD34+ HSPCs for therapeutic application to sickle cell disease and beta-thalassemia. The goal is to modify the hematopoietic stem cells of a patient to complement the loss of function of the beta-globin gene and then return these cells to the patient through an autologous transplant. Development of Cys2His2 Zinc fingers proteins (ZFPs) as targeted therapeutics: We are developing artificial ZFPs for the regulation of target genes to change their gene expression profiles for therapeutic applications.
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Lemon, Stephenie
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Ayers, David
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Goldberg, Robert
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McManus, David
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Seymour, Neal
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Research
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UMass Chan – Baystate Regional Campus
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Lagu, Tara
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Usmani, Saad
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Ophthalmology and Visual Sciences
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Population and Quantitative Health Sciences
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Stevens, Elise
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Associate Professor
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Joint Replacement
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Adjunct Professor
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Driban, Jeffrey
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Professor
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Professor
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Professor
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Walkey, Allan
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Medicine at UMass Chan - Lahey
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Surgery at UMass Chan - Lahey
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https://profiles.umassmed.edu/profile/40402890
ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury
ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA
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ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA Characteristics of Accelerated Hand Osteoarthritis Earlier Than Early Osteoarthritis (OA): Pre-OA Illness
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ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA Characteristics of Accelerated Hand Osteoarthritis Earlier Than Early Osteoarthritis (OA): Pre-OA Illness The Inverse OARSI-OMERACT Criteria for Knee OA Current State of the OAI & Intro to the Knowledgebase
ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA Characteristics of Accelerated Hand Osteoarthritis Earlier Than Early Osteoarthritis (OA): Pre-OA Illness Current State of the OAI & Intro to the Knowledgebase The Inverse OARSI-OMERACT Criteria for Knee OA
ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA Characteristics of Accelerated Hand Osteoarthritis Current State of the OAI & Intro to the Knowledgebase Earlier Than Early Osteoarthritis (OA): Pre-OA Illness The Inverse OARSI-OMERACT Criteria for Knee OA
ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA Current State of the OAI & Intro to the Knowledgebase Characteristics of Accelerated Hand Osteoarthritis Earlier Than Early Osteoarthritis (OA): Pre-OA Illness The Inverse OARSI-OMERACT Criteria for Knee OA
ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Current State of the OAI & Intro to the Knowledgebase Playing the Long Game: Consensus for Preventing OA Characteristics of Accelerated Hand Osteoarthritis Earlier Than Early Osteoarthritis (OA): Pre-OA Illness The Inverse OARSI-OMERACT Criteria for Knee OA
ProfilesRNS Plugin Searchable Data: Preventing Osteoarthritis After an ACL Injury Current State of the OAI & Intro to the Knowledgebase Playing the Long Game: Consensus for Preventing OA Earlier Than Early Osteoarthritis (OA): Pre-OA Illness Characteristics of Accelerated Hand Osteoarthritis The Inverse OARSI-OMERACT Criteria for Knee OA
ProfilesRNS Plugin Searchable Data: Current State of the OAI & Intro to the Knowledgebase Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA Earlier Than Early Osteoarthritis (OA): Pre-OA Illness Characteristics of Accelerated Hand Osteoarthritis The Inverse OARSI-OMERACT Criteria for Knee OA
ProfilesRNS Plugin Searchable Data: Current State of the OAI & Intro to the Knowledgebase Preventing Osteoarthritis After an ACL Injury Earlier Than Early Osteoarthritis (OA): Pre-OA Illness Playing the Long Game: Consensus for Preventing OA Characteristics of Accelerated Hand Osteoarthritis The Inverse OARSI-OMERACT Criteria for Knee OA
ProfilesRNS Plugin Searchable Data: Current State of the OAI & Intro to the Knowledgebase Earlier Than Early Osteoarthritis (OA): Pre-OA Illness Preventing Osteoarthritis After an ACL Injury Playing the Long Game: Consensus for Preventing OA Characteristics of Accelerated Hand Osteoarthritis The Inverse OARSI-OMERACT Criteria for Knee OA

Radiology at UMass Chan - Lahey
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Professor
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Distinguished Professor and Chair Emeritus
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Chair and Professor
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Professor
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Professor
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Cardio Thoracic Radiology
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Health System Science
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Neurointerventional Radiology
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Pulmonary Medicine
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Chandraker, Anil
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Endowed Chair Honorary Title: Jack M. Wilson Chair in Biomedical Research
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Professor Emeritus
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Professor
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Professor
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Professor
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Professor
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Professor
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Professor
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Professor
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Associate Professor
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Assistant Professor
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Stroke and Vascular Neurology
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Chair and Professor
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Associate Professor
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position in division: Health System Science
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position in organization: UMass Chan Medical School

Finlay, Andrea
first name: Andrea
last name: Finlay
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latitude: 42.27525000000000
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Professor
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position in division: https://profiles.umassmed.edu/profile/15590085
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Tan Chingfen Graduate School of Nursing
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McAlindon, Timothy
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latitude: 42.27222560000000
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Martinez, Fernando
first name: Fernando
last name: Martinez
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latitude: 42.27525000000000
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Person ID: 10247895
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Professor
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position in division: Pulmonary Medicine
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position in organization: UMass Chan Medical School

Wilcox, Susan
first name: Susan
last name: Wilcox
full name: Susan Renee Wilcox MD
has faculty rank: Professor
latitude: 42.48526100000000
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media links: https://profiles.umassmed.edu/profile/66924043
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media links: https://profiles.umassmed.edu/profile/66923911
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Summary: Dr. Wilcox trained in EM at the Harvard Affiliated EM Residency, then completed an Anesthesia Critical Care fellowship. In addition to the ED, she has attended in Surgical, Medical, and Cardiac ICUs. She joined Lahey Hospital in 2022 as the Medical Director of the 5C Medical ICU. She is Vice Chair for Academic Affairs and a Professor of Medicine. She is the Associate CMO for Boston MedFlight.
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Professor
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position in division: https://profiles.umassmed.edu/profile/15590085
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Krings, Timo
first name: Timo
last name: Krings
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Goldsweig, Andrew
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latitude: 42.12294230000000
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Ghogawala, Zoher
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has faculty rank: Professor
latitude: 42.48526100000000
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Person ID: 10248062
person in primary position: Professor
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Associate Professor
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position in department: Medicine at UMass Chan - Baystate
position in division: https://profiles.umassmed.edu/profile/15590085
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position in organization: UMass Chan – Baystate Regional Campus

Professor
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Professor Emeritus
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Maron, Martin
first name: Martin
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full name: Martin S Maron MD, MSPH
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latitude: 42.48526100000000
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Person ID: 10248121
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Maron, Barry
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Adjunct Professor
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Professor
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Chair and Professor
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Reynolds, Matthew
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latitude: 42.48526100000000
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Rowin, Ethan
first name: Ethan
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latitude: 42.48817480000000
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Person ID: 10248175
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Abelson, Jonathan
first name: Jonathan
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latitude: 42.48526100000000
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Person ID: 10248179
person in primary position: Associate Professor
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Associate Professor
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Professor
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Instructor
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Professor
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Professor Emeritus
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Assistant Professor
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Associate Professor
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Chair And Professor
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Professor Emeritus
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position in division: Health System Science
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Psychiatry and Behavioral Sciences
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Chair and Professor
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Professor
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sort order: 1
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Professor
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position in department: Population and Quantitative Health Sciences
position in division: Preventive And Behavioral Medicine
sort order: 1
type: Position
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position in organization: UMass Chan Medical School

Associate Professor
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position in department: Neurology
position in division: Stroke and Vascular Neurology
sort order: 1
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position in organization: UMass Chan Medical School

Professor
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position in department: Emergency Medicine
position in division: Research
sort order: 1
type: Position
HR job title: Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Medicine
position in division: Renal Medicine
sort order: 1
type: Position
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position in organization: UMass Chan Medical School

Professor
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position in department: Ophthalmology and Visual Sciences
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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Professor
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position in department: Medicine
position in division: Health System Science
sort order: 1
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position in organization: UMass Chan Medical School

https://profiles.umassmed.edu/profile/66923911
publication date: 2016
type: URLLink
label: https://emcrit.org/emcrit/pulmonary-hypertension-right-ventricular-failure/
link anchor text: EMCrit 181 – Pulmonary Hypertension and Right Ventricular Failure with Susan Wilcox

https://profiles.umassmed.edu/profile/66923959
publication date: 2020
type: URLLink
label: https://www.edx.org/learn/healthcare/harvard-university-mechanical-ventilation-for-covid-19
link anchor text: HarvardX: Mechanical Ventilation for COVID-19

https://profiles.umassmed.edu/profile/66924015
publication date: 2017
type: URLLink
label: https://emergencymedicinecases.com/pulmonary-hypertension/
link anchor text: CritCases 7 Pulmonary Hypertension – A Fine Balance

https://profiles.umassmed.edu/profile/66924043
publication date: 2018
type: URLLink
label: https://www.aliem.com/2018/06/myth-vasopressors-ischemia/
link anchor text: Academic Life in Emergency Medicine: The Myth of Vasopressors and Ischemia

https://profiles.umassmed.edu/profile/66924060
publication date: 2020
type: URLLink
label: https://www.acep.org/corona/covid-19-field-guide/treatment/icu-care-in-the-emergency-department/
link anchor text: ACEP COVID-19 Field Guide: ICU Care in the Emergency Department

https://profiles.umassmed.edu/profile/66924233
publication date: 2021
type: URLLink
label: https://podcasts.apple.com/us/podcast/jem-june-2021-podcast-summary/id1141686910
link anchor text: Podcast summary of articles from the June 2021 edition of the Journal of Emergency Medicine

Associate Professor
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position in department: Surgery at UMass Chan - Lahey
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sort order: 1
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
type: Position
HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Surgery at UMass Chan - Lahey
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Shin, Dong-Soo
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Vanni, Alex
first name: Alex
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full name: Alex Vanni MD, FACS
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Person ID: 10248404
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Summary: Dr. Alex J. Vanni is an internationally recognized expert in reconstructive urologic surgery and a Professor of Urology at Lahey Hospital and Medical Center, where he serves as Director of the Center for Reconstructive Urologic Surgery. He specializes in the treatment of urethral stricture disease and advanced male genitourinary reconstruction.
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webpage: https://profiles.umassmed.edu/profile/111866126

Associate Professor
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Professor
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