Health Informatics And Implementation Science
Biostatistics And Health Services Research
Donna M. and Robert J. Manning Chair in Obstetrics and Gynecology
Melvin S. and Sandra L. Cutler Chair in Biomedical Research
Potential Rotation Projects Proteostasis regulators, HSF1, HSP70 and HSP90 in liver disease: Determine the expression and function in different cell types of the liver during acute and chronic liver injury using in vivo and in vitro models. Subsequently, we will test the relevance of the expression of these proteins in activation of intracellular signaling molecules involved in induction of fatty liver, inflammation and fibrosis. Role of chemokines in liver disease: CC-chemokines particularly CCL2/MCP-1, is significantly increased in serum as well as in the liver parenchyma in patients with alcoholic hepatitis. We test the role of MCP-1 in induction of fatty acid synthesis or metabolism and inflammation in the alcoholic liver. Our studies will also investigate the role of MCP-1 directed migration of immune cells in the liver contributing to injury.
Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
Rotation projects are available related to microbiota-gut brain axis and antibiotic usage and the sequelae of antibiotic use in hospitalized patients which include Clostridium difficile and multi-drug resistant organism infection and colonization.
Associate Professor in the Division of Geriatric Medicine in the Department of Medicine at UMMS Chan. Her research focuses on the magnitude, management, and clinical outcomes associated with the presence of multiple chronic conditions in older adults (MCC). I have been awarded a NIA RO1 grant to examine the treatment patterns of selected therapies in patients with heart failure and MCC.
Richard M. Haidack Professor in Medicine
Brian Silver MD, FRCPC, FAHA, FAAN, FANA
Population and Quantitative Health Sciences
Emergency Medicine at UMass Chan - Baystate
Healthcare Delivery and Population Sciences at UMass Chan - Baystate
Worcester Foundation for Biomedical Research Chair I
Susan D Moffatt-Bruce MD, PhD, FRCSC, MBOE, MBA,FACS
Emergency Medicine at UMass Chan - Lahey
Sourbha S Dani MD, MSc, GDCE, CCDS, FACC,FACP
Dr. Wilcox trained in EM at the Harvard Affiliated EM Residency, then completed an Anesthesia Critical Care fellowship. In addition to the ED, she has attended in Surgical, Medical, and Cardiac ICUs. She joined Lahey Hospital in 2022 as the Medical Director of the 5C Medical ICU. She is Vice Chair for Academic Affairs and a Professor of Medicine. She is the Associate CMO for Boston MedFlight.
Advisory links alcohol consumption to cancers: Here's how Worcester feels about the report
EMCrit 181 – Pulmonary Hypertension and Right Ventricular Failure with Susan Wilcox
HarvardX: Mechanical Ventilation for COVID-19
CritCases 7 Pulmonary Hypertension – A Fine Balance
Academic Life in Emergency Medicine: The Myth of Vasopressors and Ischemia
ACEP COVID-19 Field Guide: ICU Care in the Emergency Department
Podcast summary of articles from the June 2021 edition of the Journal of Emergency Medicine