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Obstetrics and Gynecology
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Orthopedics and Physical Rehabilitation
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Medicine
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Neurobiology
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Pathology
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Pediatrics
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Program in Molecular Medicine
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Radiology
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RNA Therapeutics Institute
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Surgery
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College of Engineering
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College of Natural Sciences
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Chemical Engineering
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Chemistry
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Department of Food Science
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Food Science
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Veterinary And Animal Science
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Gastroenterology
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General Surgery
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Health Informatics And Implementation Science
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Hematology/Oncology
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Maternal-Fetal Medicine
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Anatomic Pathology
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Surgical Oncology
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Vascular Surgery
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UMass Chan Medical School
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University of Massachusetts Amherst
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Akalin, Ali
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full name: Ali Akalin MD, PhD
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Simin, Karl
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Flotte, Terence
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Endowed Chair Honorary Title: Elisabeth Chair for the Dean of Medicine
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Zhu, Lihua
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Kelliher, Michelle
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Endowed Chair Honorary Title: Our Danny Cancer Fund Chair in Biomedical Research I
Post Docs: A postdoctoral position is available to study in this laboratory. Contact Dr. Kelliher for additional details.
Rotation Projects: Please visit the Kelliher Lab website at: http://labs.umassmed.edu/kelliherlab/ to learn more about our current research areas. 1. Identify genes/pathways that mediate leukemia-initiating cell survival 2. Understand the molecular basis of glucocorticoid resistance in leukemia 3. Examine contribution of RIPK1 kinase in inflammatory and autoimmune disease mouse models. 4. Reveal tissue-specific roles for RIPK1 in cell death and inflammation. Use conditional Ripk1 allele to investigate effects of Ripk1 deletion in liver, pancreas and antigen presenting cells.
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Gao, Guangping
first name: Guangping
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Endowed Chair Honorary Title: Penelope Booth Rockwell Chair in Biomedical Research
Lab URL: https://www.umassmed.edu/gaolab/
Summary: Focus: Adeno-associated virus vector mediated gene transfer for gene therapy, gene therapy of inherited neurodegenerative Canavan Disease
preferred title: Chair and Professor

Mao, Junhao
first name: Junhao
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Post Docs: Postdoctoral positions are available for this lab. Please contact Junhao Mao directly, 508-856-4149 or via email, Junhao.Mao@umassmed.edu
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webpage: https://profiles.umassmed.edu/profile/28866544

McCormick, Beth
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Endowed Chair Honorary Title: Worcester Foundation for Biomedical Research Chair II
Lab URL: https://www.umassmed.edu/mccormicklab/
Summary: Focus: Mucosal inflammation, host: pathogen interactions, and cancer biology
preferred title: Chair and Professor

Hutchinson, Lloyd
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full name: Lloyd Hutchinson PhD
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Swain, Susan
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Post Docs: An entry level postdoctoral position is open immediately in the laboratory of Dr. Susan L. Swain to study the factors that control the development and survival of CD4 and CD8 T cell memory. Graduate student experience with tissue culture, in vitro assay, flow cytometry, experience in mouse models on infectious disease and a knowledge of cellular and molecular immunology are all strongly desired.
Rotation Projects: <p >Rotations: Projects in the following areas <p >CD4 T cell memory. We can generate in vitro CD4 T cells that are for all extents and purposes identical to the memory CD4 T cells observed in vivo. In situ memory CD4 T cells persist at very low frequency and in most instances it is difficult to analyze them thoroughly using tetramer or multimer reagents both because of their low frequency and the relatively low specific affinity of the Class II reagents for the TcR. Being able to generate “recent” memory cells in vitro gives us the opportunity to analyze in detail the mechanisms by which memory CD4 T cells may contribute to secondary immunity and immune protection. Once identified. will determine if particular pathways are relevant in situ. We have discovered that memory CD4 T cells are superior in protection to those from the primary response and that they display pleitropic functions that have not been previously identified. <p > Cytotoxic CD4 Effectors. One unexpected function of CD4 T cells we identified is robust, perforin-dependent cytotoxic activity (7, 16). Cytotoxic activity by CD4 T cells has been reported in response to several infections, but its significance has not heretofore been established. We find that “Th1 polarized” CD4 effectors and more relevantly the CD4 effectors found in the lung following influenza infection, are able to kill infected or peptide-pulsed Class II-bearing targets and we find that this perforin dependent activity can work together with antibody to provide protection against lethal influenza challenge in otherwise unprimed mice (17). We also will determine when memory CD4 T cells re-express cytotoxic activity following in vivo challenge and how cytotoxic killing contributes to the memory cell mediated protection. We want to analyze how the program of cytotoxicity is induced in these “ThCTL”. <p > Memory CD4 Cells Enhance an Innate Response. Memory cells can act by becoming secondary effectors but they are best characterized by …
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Latz, Eicke
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Bergmann, Andreas
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Post Docs: Please contact the Human Resources at UMass for openings in Dr. Bergmann's lab.
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Swanson, Richard
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person in primary position: Adjunct Associate Professor
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Fitzgerald, Katherine
first name: Katherine
last name: Fitzgerald
full name: Katherine A Fitzgerald PhD
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Person ID: 202
person in primary position: Professor
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Endowed Chair Honorary Title: Worcester Foundation for Biomedical Research Chair III
Rotation Projects: Please email Kate.Fitzgerald@umassmed.edu if you are interested in rotations.
preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/28866427
webpage: https://profiles.umassmed.edu/profile/28866493

Shultz, Leonard
first name: Leonard
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Davis, Roger
first name: Roger
last name: Davis
full name: Roger J Davis PhD, FRS
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Endowed Chair Honorary Title: H. Arthur Smith Chair in Cancer Research
Rotation Projects: Rotation Projects Laboratory rotations are available to study signal mammalian transduction mechanisms. Several projects are available, including studies of protein kinase cascades, gene expression, the cell cycle, and apoptosis. Targeted gene disruption approaches in mice combined with biochemical and molecular biology studies will be examined.
preferred title: Chair and Professor
webpage: https://profiles.umassmed.edu/profile/28866429

Zierath, Juleen
first name: Juleen
last name: Zierath
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Xiang, Yang
first name: Yang
last name: Xiang
full name: Yang Xiang PhD
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Person ID: 3180
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Rotation Projects: One rotation student is expected in the lab to characterize the expression and function of Drosophila gustatory receptor 28b (Gr28b) in phototransduction and taste sensation. Please contact Dr. Yang Xiang for details.<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p> <o:p> </o:p> Yang Xiang, Ph.D. University of Massachusetts Medical School Department of Neurobiology, LRB 725 364 Plantation Street Worcester, MA 01605 USA phone: 508-856-6816 (office) e-mail: yang.xiang@umassmed.edu<o:p></o:p>
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LaFemina, Jennifer
first name: Jennifer
last name: LaFemina
full name: Jennifer LaFemina MD
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Heneka, Michael
first name: Michael
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full name: Michael Thomas Heneka MD
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Szabo, Gyongyi
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo MD, PhD
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Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
preferred title: Adjunct Professor

Simons, Jessica
first name: Jessica
last name: Simons
full name: Jessica P Simons MD, MPH
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Person ID: 3626
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Lian, Jane
first name: Jane
last name: Lian
full name: Jane B Lian PhD
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Rotello, Vincent
first name: Vincent
last name: Rotello
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Person ID: 3741
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Fissore, Rafael
first name: Rafael
last name: Fissore
full name: Rafael A Fissore DVM-PhD
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McClements, David
first name: David
last name: McClements
full name: David J McClements B.S., Ph.D.
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Person ID: 3760
person in primary position: Fergus Clydesdale Endowed Chair
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preferred title: Fergus Clydesdale Endowed Chair

Forbes, Neil
first name: Neil
last name: Forbes
full name: Neil Forbes PhD
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Person ID: 3764
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Xiao, Hang
first name: Hang
last name: Xiao
full name: Hang Xiao PhD
has faculty rank: Associate Professor
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Person ID: 3795
person in primary position: Associate Professor
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Imbalzano, Anthony
first name: Anthony
last name: Imbalzano
full name: Anthony N Imbalzano PhD
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Person ID: 507
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Post Docs: Please contact Dr. Imbalzano to discuss the possibility of a postdoctoral training.See lab research interests and publications for recent topics of research. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
Rotation Projects: Please contact Dr. Imbalzano to discuss the possibility of a rotation project. Rotation projects are generally based on current work and tailored to the interests of the student. See lab research interests and publications for recent topics. http://www.umassmed.edu/imbalzanolab/ http://www.umassmed.edu/imbalzanolab/publications/
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Greiner, Dale
first name: Dale
last name: Greiner
full name: Dale L Greiner PhD
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Person ID: 612
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Endowed Chair Honorary Title: Herman G. Berkman Chair in Diabetes Care Innovation
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Pazour, Gregory
first name: Gregory
last name: Pazour
full name: Gregory J Pazour PhD
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Person ID: 621
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Rotation Projects: Potential Rotation Projects Rotation projects in my laboratory will involve questions of how cilia are assembled and the function these organelles play in mammals. Projects vary depending on ongoing work in the laboratory and interests of the rotation student. Rotations in my laboratory can give students exposure to a range of techniques from mouse breeding and histological analysis of mouse tissues to mammalian cell culture and other cell biological techniques.
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webpage: https://profiles.umassmed.edu/profile/41661165

Whalen, Giles
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Lewis, Brian
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Endowed Chair Honorary Title: George F. Booth Chair in the Basic Sciences
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Shaw, Leslie
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Mercurio, Arthur
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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
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Pediatric Genetics
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Haynes, Cole
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Department Head
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Chair and Professor
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Fergus Clydesdale Endowed Chair
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Associate Professor
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Krieg, Arthur
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ADJUNCT ASSOCIATE PROFESSOR
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ADJUNCT PROFESSOR
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Lalani, Tasneem
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Lindberg, James
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Strauss, Kevin
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Barile, Maria
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Population and Quantitative Health Sciences
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Marya, Neil
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Johnson, Katherine
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Ruscetti, Marcus
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Biochemistry and Molecular Biotechnology
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https://profiles.umassmed.edu/profile/28866429
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Adjunct Professor
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Professor
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Professor
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Adjunct Professor
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Professor
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Professor
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Professor
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Professor
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Associate Professor
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Professor
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Professor
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Pitarresi, Jason
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Spinelli, Jessica
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Weiss, Glen
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Professor
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Chair and Professor
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Associate Professor
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Professor
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Assistant Professor
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Associate Professor
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Medicine at UMass Chan - Lahey
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Surgery at UMass Chan - Lahey
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Pathology at UMass Chan - Lahey
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Radiology at UMass Chan - Lahey
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Abdominal Imaging
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Associate Professor
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Basic Pathology
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Cardio Thoracic Radiology
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Endocrinology & Diabetes
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Health System Science
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Infectious Diseases
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Innate Immunity
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Orthopedics Research
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Pulmonary Medicine
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Adjunct Professor
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Professor
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Adjunct Professor
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Professor
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Professor
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Adjunct Professor
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Assistant Professor
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Adjunct Associate Professor
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Professor
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Assistant Professor
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Martinez, Fernando
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Professor
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Microbiology
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Chair and Professor
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Professor Emeritus
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Perrino, Carmen
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Assistant Professor
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Professor
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Nakeeb, Attila
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Professor
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Labadie, Brian
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Assistant Professor
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Instructor
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Professor
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Professor Emeritus
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Assistant Professor
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Associate Professor
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Chair And Professor
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Professor
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Associate Professor
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Professor
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Genetic and Cellular Medicine
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Assistant Professor
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Professor
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Adjunct Professor
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Assistant Professor
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Shin, Dong-Soo
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Watkins, Ammara
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Chair and Professor
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Professor
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Vyas, Jatin
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Assistant Professor
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Rieger-Christ, Kimberly
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Associate Professor
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Adjunct Professor
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