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Obstetrics and Gynecology
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School of Public Health and Health Sciences
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Family Medicine and Community Health
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Medicine
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Neurobiology
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Program in Molecular Medicine
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RNA Therapeutics Institute
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College of Nursing
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Cardiovascular Medicine
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Chemistry
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Electrical And Computer Engineering
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Epidemiology
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Food Science
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Psychology And Neuroscience & Behavior Program
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Public Health
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School of Nursing
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Gastroenterology
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Geriatrics
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Health Informatics And Implementation Science
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Hematology/Oncology
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Maternal-Fetal Medicine
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Preventive And Behavioral Medicine
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Rheumatology
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Biostatistics And Epidemiology
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UMass Chan Medical School
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University of Massachusetts Amherst
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Pagoto, Sherry
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Moore Simas, Tiffany
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Kiefe, Catarina
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Ware, John
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Chair and Professor
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Latz, Eicke
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Fitzgerald, Katherine
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Endowed Chair Honorary Title: Worcester Foundation for Biomedical Research Chair III
Rotation Projects: Please email Kate.Fitzgerald@umassmed.edu if you are interested in rotations.
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webpage: https://profiles.umassmed.edu/profile/28866427
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Shultz, Leonard
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Armstrong, Elizabeth
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Davis, Roger
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Endowed Chair Honorary Title: H. Arthur Smith Chair in Cancer Research
Rotation Projects: Rotation Projects Laboratory rotations are available to study signal mammalian transduction mechanisms. Several projects are available, including studies of protein kinase cascades, gene expression, the cell cycle, and apoptosis. Targeted gene disruption approaches in mice combined with biochemical and molecular biology studies will be examined.
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Zierath, Juleen
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Xiang, Yang
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Rotation Projects: One rotation student is expected in the lab to characterize the expression and function of Drosophila gustatory receptor 28b (Gr28b) in phototransduction and taste sensation. Please contact Dr. Yang Xiang for details.<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p> <o:p> </o:p> Yang Xiang, Ph.D. University of Massachusetts Medical School Department of Neurobiology, LRB 725 364 Plantation Street Worcester, MA 01605 USA phone: 508-856-6816 (office) e-mail: yang.xiang@umassmed.edu<o:p></o:p>
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Lapane, Kate
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Heneka, Michael
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Szabo, Gyongyi
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Post Docs: Immediate opening! Two postdoctoral positions are available immediately to study cellular andmolecular mechanisms resulting in immunosuppression after alcohol use. Thefocus of this research is the role of monocytes and dendritic cells indecreased antigen-specific T cell activation after alcohol use.Intracellular signalling mechanisms resulting in decreased NF-kBactivation and inflammatory cytokine induction after acute alcoholconsumption are being investigated. Please contact Dr. Szabo for details.
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Hayman, Laura
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Chasan-Taber, Lisa
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Jacelon, Cynthia
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Bertone-Johnson, Elizabeth
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Rotello, Vincent
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Xiao, Hang
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Spencer, Rebecca
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Whitcomb, Brian
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Xia, Qiangfei
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Crawford, Sybil
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Harris, John
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Endowed Chair Honorary Title: Lambi and Sarah Adams Chair in Genetic Research
Rotation Projects: Rotations: Targeting the IFN-?-chemokine axis for treatment of vitiligo: We are using our newly developed mouse model and human tissues from patients with vitiligo to identify the cytokines and chemokines that are expressed within the depigmenting skin and which skin cells produce them. We are using genetically modified mouse strains (knockouts, conditional knockouts, fluorescent reporter strains), and cytokine and chemokine neutralizing antibodies to identify the key proteins required for disease. This data will permit us to rationally develop and test new therapeutic agents. Understanding the proinflammatory signals generated by melanocytes under cellular stress. Melanocytes from vitiligo patients have intrinsic abnormalities, including cellular stress evidenced by increased production of reactive oxygen species (ROS) and activation of the unfolded protein response (UPR). The immune system has evolved to recognize this stress as damage-associated molecular patterns (DAMPs), which activate innate immunity. We are using human cells and tissues to determine how cellular stress, innate immunity, and adaptive immunity cooperate to initiate and perpetuate depigmentation in vitiligo. Developing a humanized mouse model of immune-skin interactions to serve as a pre-clinical bridge to clinical studies: We are developing a humanized mouse model of skin disease that consists of an immunodeficient mouse strain as a host for an autologous human skin graft and immune reconstitution in order to study mechanisms of inflammation in the skin, including allergic contact dermatitis, response to infection, tumor immunotherapy, and autoimmunity, all within a fully human environment. This model system will act as a pre-clinical bridge between mouse models and human clinical trials, providing an opportunity to test new treatments on human cells and tissues prior to initiating trials on patients. Tracking real-time autoreactive T cell migration and interactions within the skin: We are usin…
Rotation Projects: Rotations: Targeting the IFN-g-chemokine axis for treatment of vitiligo: We are using our newly developed mouse model and human tissues from patients with vitiligo to identify the cytokines and chemokines that are expressed within the depigmenting skin and which skin cells produce them. We are using genetically modified mouse strains (knockouts, conditional knockouts, fluorescent reporter strains), and cytokine and chemokine neutralizing antibodies to identify the key proteins required for disease. This data will permit us to rationally develop and test new therapeutic agents. Understanding the proinflammatory signals generated by melanocytes under cellular stress. Melanocytes from vitiligo patients have intrinsic abnormalities, including cellular stress evidenced by increased production of reactive oxygen species (ROS) and activation of the unfolded protein response (UPR). The immune system has evolved to recognize this stress as damage-associated molecular patterns (DAMPs), which activate innate immunity. We are using human cells and tissues to determine how cellular stress, innate immunity, and adaptive immunity cooperate to initiate and perpetuate depigmentation in vitiligo. Developing a humanized mouse model of immune-skin interactions to serve as a pre-clinical bridge to clinical studies: We are developing a humanized mouse model of skin disease that consists of an immunodeficient mouse strain as a host for an autologous human skin graft and immune reconstitution in order to study mechanisms of inflammation in the skin, including allergic contact dermatitis, response to infection, tumor immunotherapy, and autoimmunity, all within a fully human environment. This model system will act as a pre-clinical bridge between mouse models and human clinical trials, providing an opportunity to test new treatments on human cells and tissues prior to initiating trials on patients. Tracking autoreactive T cell interactions within the skin: We are using fluorescently tagged C…
Summary: Interests: Vitiligo, autoimmunity, immunology, translational research
preferred title: Adjunct Professor

Goldberg, Robert
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Byatt, Nancy
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Mercurio, Arthur
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Rotation Projects: <p >Rotation Projects <p >Rotation projects are designed to expose students to the molecular cell biology of solid tumors and to provide them with an appreciation for translational cancer research. Specific rotation projects, which are focused on the major themes of the lab, include: <p >Function and Regulation of Integrins (Cell Adhesion Receptors) in Cancer Epigenetic mechanisms that regulate integrin gene expression in human cancers Regulation of integrin expression and function during the EMT Role of specfic microRNAs (miRs) in regulating integrin function and signaling Contribution of integrins to carcinoma progression using mouse models of breast carcinoma <p >Vascular Endothelial Growth Factor (VEGF) Signaling, EMT and Carcinoma Progression Function and expression of VEGF receptors in carcinoma cells Regulation of VEGF transcription in response to EMT stimuli Role of miRs in regulating VEGF receptors and signaling Contribution of VEGF signaling to the behavior of aggressive, de-differentiated carcinomas <p >Nuclear Hormone Receptors and EMT Role of estrogen receptors in regulating the EMT Regulation of VEGF transcription by estrogen receptors
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McManus, David
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Endowed Chair Honorary Title: Richard M. Haidack Professor in Medicine
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Friedmann, Peter
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UMass Chan – Baystate Regional Campus
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Dermatology
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Singh, Sonal
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Mittal, Kriti
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Professor
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Lindenauer, Peter
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ADJUNCT ASSISTANT PROFESSOR
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Usmani, Saad
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Ophthalmology and Visual Sciences
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Population and Quantitative Health Sciences
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Yonkers, Kimberly
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person in primary position: Chair and Professor
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Sacha, Caitlin
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Matteson, Kristen
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latitude: 42.27287580000000
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https://profiles.umassmed.edu/profile/28866493
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Family Medicine at UMass Chan - Baystate
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Healthcare Delivery and Population Sciences at UMass Chan - Baystate
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Medicine at UMass Chan - Baystate
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Adjunct Professor
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position in organization: UMass Chan Medical School

Adjunct Professor
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Adjunct Professor
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Instructor
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Professor
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Adjunct Professor
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Mullen, Alan
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Endowed Chair Honorary Title: Mary C. DeFeudis Chair in Biomedical Research
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Lee, Darren
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latitude: 42.27525000000000
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Person ID: 10247152
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webpage: https://profiles.umassmed.edu/profile/35298484

Weiss, Glen
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has faculty rank: Associate Professor
latitude: 42.27525000000000
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Person ID: 10247163
person in primary position: Associate Professor
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Nasser-Ghodsi, Navine
first name: Navine
last name: Nasser-Ghodsi
full name: Navine Nasser-Ghodsi MD
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latitude: 42.27525000000000
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Person ID: 10247184
person in primary position: Assistant Professor
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Associate Professor
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Chair and Professor
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position in department: Program in Molecular Medicine
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HR job title: Chair and Professor
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https://profiles.umassmed.edu/profile/34727929
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https://profiles.umassmed.edu/profile/35298484
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Assistant Professor
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position in department: Medicine
position in division: Gastroenterology
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position in organization: UMass Chan Medical School

Associate Professor
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sort order: 1
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Professor
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HR job title: Professor
position in organization: UMass Chan Medical School

Wilkie, Gianna
first name: Gianna
last name: Wilkie
full name: Gianna L Wilkie MD, MSCI
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latitude: 42.27222560000000
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Person ID: 10247561
person in primary position: Assistant Professor
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preferred title: Assistant Professor

Associate Professor
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position in department: Neurobiology
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sort order: 1
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Whelan, Anna
first name: Anna
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full name: Anna Rosalie Whelan MD, FACOG
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latitude: 42.27222560000000
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Person ID: 10247584
person in primary position: Assistant Professor
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preferred title: Assistant Professor

Walkey, Allan
first name: Allan
last name: Walkey
full name: Allan Jay Walkey MD, MSc
has faculty rank: Professor
latitude: 42.27525000000000
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Person ID: 10247602
person in primary position: Professor
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preferred title: Professor
webpage: https://profiles.umassmed.edu/profile/104051488

Medicine at UMass Chan - Lahey
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Surgery at UMass Chan - Lahey
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Pathology at UMass Chan - Lahey
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Radiology at UMass Chan - Lahey
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Associate Professor
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position in department: Obstetrics and Gynecology
position in division: Maternal-Fetal Medicine
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position in organization: UMass Chan Medical School

Endocrinology & Diabetes
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Health System Science
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Infectious Diseases
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Innate Immunity
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Pulmonary Medicine
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Reproductive
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Professor Emeritus
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position in division: Epidemiology
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Adjunct Professor
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Professor
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Professor
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Professor
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Adjunct Professor
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Assistant Professor
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position in division: Maternal-Fetal Medicine
sort order: 1
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position in organization: UMass Chan Medical School

Professor
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Assistant Professor
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position in division: Maternal-Fetal Medicine
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Ob/Gyn General
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Chair and Professor
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position in department: Medicine
position in division: Cardiovascular Medicine
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position in organization: UMass Chan Medical School

Tan Chingfen Graduate School of Nursing
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Chung, Joohyun
first name: Joohyun
last name: Chung
full name: Joohyun Chung PhD, MStat, RN
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latitude: 42.39152670000000
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Person ID: 10247836
person in primary position: Adjunct Assistant Professor
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Adjunct Assistant Professor
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position in department: Medicine at UMass Chan - Baystate
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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HR job title: Adjunct Assistant Professor
position in organization: UMass Chan – Baystate Regional Campus

McAlindon, Timothy
first name: Timothy
last name: McAlindon
full name: Timothy Edward McAlindon MD, MPH, MRCP
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latitude: 42.27222560000000
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Person ID: 10247852
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Martinez, Fernando
first name: Fernando
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has faculty rank: Chair And Professor
latitude: 42.27525000000000
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Person ID: 10247895
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Endowed Chair Honorary Title: Joseph D. Early Chair in Biomedical Research
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Instructor
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position in department: Family Medicine at UMass Chan - Baystate
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HR job title: Instructor
position in organization: UMass Chan – Baystate Regional Campus

Abu, Hawa
first name: Hawa
last name: Abu
full name: Hawa Ozien Abu MD, PhD, MPH
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latitude: 42.27525000000000
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Person ID: 10247945
person in primary position: Assistant Professor
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preferred title: Assistant Professor

Krings, Timo
first name: Timo
last name: Krings
full name: Timo Krings MD, PhD, FRCP
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latitude: 42.48526100000000
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Person ID: 10247952
person in primary position: Professor
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Perrino, Carmen
first name: Carmen
last name: Perrino
full name: Carmen Perrino MD
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latitude: 42.48526100000000
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Person ID: 10248039
person in primary position: Assistant Professor
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Assistant Professor
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sort order: 1
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HR job title: Assistant Professor
position in organization: UMass Chan Medical School

Professor Emeritus
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HR job title: Professor Emeritus
position in organization: UMass Chan Medical School

Wu, Meng-Ju
first name: Meng-Ju
last name: Wu
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full name: Meng-Ju Wu PhD
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latitude: 42.27525000000000
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Person ID: 10248072
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Lab URL: https://www.mjwulab.org/
Summary: We focus on how changes in metabolism and epigenetics contribute to cancer development and immune system evasion. Using techniques such as mouse models, cellular immunology and functional genomics, we aim to uncover mechanisms that allow cancers to escape immune detection and develop new therapeutic strategies. We aim to develop novel, more effective, and personalized cancer therapies.
preferred title: Assistant Professor

Maron, Martin
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latitude: 42.48526100000000
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Maron, Barry
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latitude: 42.48526100000000
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Person ID: 10248130
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Adjunct Professor
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Professor
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position in department: Medicine
position in division: Rheumatology
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HR job title: Professor
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https://profiles.umassmed.edu/profile/56473360
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Chair and Professor
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position in department: Healthcare Delivery and Population Sciences at UMass Chan - Baystate
position in division: https://profiles.umassmed.edu/profile/15590085
sort order: 1
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position in organization: UMass Chan – Baystate Regional Campus

Reynolds, Matthew
first name: Matthew
last name: Reynolds
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has faculty rank: Professor
latitude: 42.48526100000000
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Person ID: 10248173
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Professor
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Assistant Professor
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Instructor
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Professor
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Professor Emeritus
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Assistant Professor
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Associate Professor
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Chair And Professor
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Clements, Matthew
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latitude: 42.48526100000000
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Person ID: 10248274
person in primary position: Assistant Professor
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Professor
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Assistant Professor
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sort order: 1
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position in organization: UMass Chan Medical School

Psychiatry and Behavioral Sciences
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Chair and Professor
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sort order: 1
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Professor
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sort order: 1
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position in organization: UMass Chan Medical School

Professor
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position in department: Tan Chingfen Graduate School of Nursing
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sort order: 1
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Chair and Professor
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position in department: Obstetrics and Gynecology
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sort order: 1
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Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
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Associate Professor
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position in division: Health System Science
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Adjunct Assistant Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
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position in organization: UMass Chan Medical School

Sim, Jin-ah
first name: Jin-ah
last name: Sim
full name: Jin-ah Sim PhD
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Person ID: 10248291
person in primary position: Adjunct Assistant Professor
type: Agent
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Assistant Professor
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position in division: Geriatrics
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position in organization: UMass Chan Medical School

Professor
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sort order: 1
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Adjunct Professor
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position in department: Population and Quantitative Health Sciences
position in division: Health Informatics And Implementation Science
sort order: 1
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position in organization: UMass Chan Medical School

Shin, Dong-Soo
first name: Dong-Soo
last name: Shin
full name: Dong-Soo Shin PhD, RN
has faculty rank: ADJUNCT PROFESSOR
Person ID: 10248397
person in primary position: Adjunct Professor
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Associate Professor
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position in department: Medicine at UMass Chan - Lahey
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sort order: 1
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HR job title: Associate Professor
position in organization: UMass Chan Medical School

Professor
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position in department: Radiology at UMass Chan - Lahey
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sort order: 1
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HR job title: Professor
position in organization: UMass Chan Medical School

Adjunct Professor
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position in department: Dermatology
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sort order: 1
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HR job title: Adjunct Professor
position in organization: UMass Chan Medical School

Assistant Professor
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position in division: Gastroenterology
sort order: 1
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position in organization: UMass Chan Medical School

Associate Professor
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position in department: Medicine
position in division: Hematology/Oncology
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position in organization: UMass Chan Medical School